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antihypertensive agent +   
benzothiadiazine +     
diuretic +   
(2R,3S,2'R)-nadolol +   
(R)-nicardipine +   
(S)-nicardipine +   
(S)-timolol (anhydrous) +   
(S)-timolol hemihydrate 
(S)-timolol maleate 
2-hydroxyoleic acid 
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine  
3-fluoro-6a,7,8,9,10,11-hexahydro-6H-azepino[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide 
4-hydroxychalcone  
6-chloro-1,1-dioxo-3-[(prop-2-enylthio)methyl]-3,4-dihydro-2H-1$l^\{6\},2,4-benzothiadiazine-7-sulfonamide 
6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1$l^\{6\},2,4-benzothiadiazine-7-sulfonamide 
6-O-galloyl-beta-D-glucose 
7-chloro-3-methyl-3,4-dihydro-2H-1$l^\{6\},2,4-benzothiadiazine 1,1-dioxide 
acebutolol  
acebutolol hydrochloride 
acetazolamide +   
ACT-132577 +   
ajmalicine  
alfuzosin +   
aliskiren +   
aliskiren fumarate 
alpha-methyl-L-dopa +   
alpha-methyl-L-dopa ethyl ester 
alpha-methyl-L-tyrosine 
alprenolol +   
amiloride +   
amiloride hydrochloride +  
amiloride hydrochloride dihydrate 
amlodipine +   
amlodipine benzenesulfonate +  
angiotensin (1-9) 
angiotensin (1-9) dizwitterion 
apelin-13 
aquaretic +   
atenolol +   
auraptene  
azilsartan +   
azilsartan kamedoxomil 
azilsartan medoxomil 
BAY 41-2272 
bemetizide 
bendroflumethiazide +   
bentazone  
benzthiazide 
Benzylhydrochlorothiazide 
bepridil +   
beraprost  
beraprost sodium 
betaxolol +   
betaxolol hydrochloride +  
bethanidine +  
bethanidine sulfate 
bevantolol +   
bevantolol hydrochloride +  
bexagliflozin  
bimatoprost 
bisoprolol +   
bopindolol  
bosentan +   
bretylium +   
bretylium tosylate  
brimonidine +   
bumetanide  
butizide 
Byvalson 
caffeine +   
camostat  
camostat mesylate 
candesartan  
captopril +   
carmoxirole  
carmoxirole hydrochloride 
carteolol  
carteolol hydrochloride 
carvedilol  
cassaine 
chlormerodrin +  
chlorothiazide 
cilazapril +   
cilazapril monohydrate  
cilnidipine  
cinaciguat  
cleistanthin A 
cleistanthin B +  
clonidine +   
colforsin daropate 
colforsin daropate hydrochloride  
corilagin  
cyclothiazide  
3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.
debrisoquin +   
diazoxide  
diltiazem  
diltiazem hydrochloride 
dorzolamide +   
dorzolamide hydrochloride  
doxazosin +   
droxidopa 
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor +   
efonidipine 
enalapril +   
enalapril maleate 
enalaprilat (anhydrous) +   
enalaprilat dihydrate  
enrasentan  
epitizide 
eplerenone  
eprosartan +   
eprosartan methanesulfonate 
Ethiazide 
ethoxzolamide  
fasudil  
fasudil hydrochloride +  
fasudil hydrochloride hydrate 
felodipine  
fenoldopam  
flumethiazide 
fluprostenol +   
forasartan 
forskolin +   
fosinopril  
fosinopril sodium 
fosinoprilat +   
G-1 
grayanotoxin I 
GSK2181236A  
guanadrel 
guanadrel sulfate 
guanethidine +   
guanethidine monosulfate +  
guanethidine sulfate 
HU-308  
hydralazine +   
hydralazine hydrochloride 
hydrochlorothiazide  
hydroflumethiazide 
imidapril +   
imidaprilat  
indanomycin 
indapamide  
irbesartan  
isoamyl nitrite 
isopropyl unoprostone 
kaempferide +   
ketanserin  
ketanserin tartrate 
labetalol  
latanoprost  
latanoprost free acid +   
lisinopril dihydrate  
lofexidine 
loop diuretic +   
losartan +   
macitentan  
mebutizide 
Methyclothiazide 
metipranolol  
metipranolol hydrochloride 
metolazone  
metoprolol  
minoxidil  
morin  
nadolol  
nebivolol  
nebivolol hydrochloride +  
nelociguat 
nerolidol +   
nicardipine  
nimodipine  
nisoldipine  
nitrendipine  
norverapamil  
oleuropein +   
olmesartan  
osmotic diuretic +   
palmitoyl ethanolamide  
pentamethonium +  
pentamethonium bromide 
pentolinium tartrate  
perindopril  
perindopril arginine +  
perindopril erbumine 
perindoprilat 
pindolol +   
Polythiazide 
potassium citrate (anhydrous) +   
potassium citrate monohydrate  
potassium nitrite 
praliciguat 
pratosartan 
prazosin +   
Prestalia 
propranolol +   
quinapril 
quinapril hydrochloride  
quinaprilat  
quinethazone 
remikiren 
rescinnamine  
reserpine  
riociguat  
rottlerin  
scoparone  
sodium nitrite  
solasodine +   
sotagliflozin 
sparsentan 
spirapril  
spiraprilat +   
spironolactone  
teclothiazide 
telmisartan  
terazosin +   
tienilic acid  
tolazoline  
torasemide +   
trandolapril  
trandolaprilat +   
travoprost 
treprostinil +   
triamterene  
trichlormethiazide  
trimethaphan +   
trimethaphan camsylate 
trimethoprim +   
U50488  
U69593  
unoprostone +  
valsartan +   
verapamil  
vericiguat 
vincamine  
visnagin 
xyloketal B 
zibotentan 
zolasartan 

Synonyms
Exact Synonyms: 3-(bicyclo[2.2.1]hept-5-en-2-yl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Related Synonyms: 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ;   6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide ;   6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ;   Formula=C14H16ClN3O4S2 ;   InChI=1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20) ;   InChIKey=BOCUKUHCLICSIY-UHFFFAOYSA-N ;   SMILES=NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C2CC3CC2C=C3)cc1Cl ;   ciclotiazida ;   cyclothiazidum
Alternate IDs: CHEBI:47361 ;   CHEBI:598653
Xrefs: Beilstein:722843 ;   CAS:2259-96-3 ;   DrugBank:DB00606 ;   Drug_Central:761 ;   KEGG:C12685 ;   KEGG:D01256 ;   LINCS:LSM-4421
Xref Mesh: MESH:C004639
Xrefs: PDBeChem:CYZ ;   PMID:19338354 ;   Patent:US3275625 ;   Wikipedia:Cyclothiazide

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