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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:multigenerational maternal exposure to hyperglycemia
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Accession:XCO:0001530 term browser browse the term
Definition:This is any condition in which the main influencing factor is any maternal exposure to hyperglycemia (blood glucose level > 180 mg/dl) that has multigenerational effects. This is a condition typically studied to determine the effect of maternal (F0) hyperglycemia exposure on the F1 offspring, but can also affect the F2 generation by direct effects on the germline of the gestating or preweaning F1 offspring. The maternal exposure may be any time before pregnancy (pregestational) up to the time of weaning of offspring.
Synonyms:exact_synonym: multigenerational maternal exposure to high blood glucose;   multigenerational maternal exposure to high blood sugar
 xref: PMID:32595139


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  experimental condition 2376
    chemical 1266
      chemical with specified structure 1131
        carbohydrate 193
          monosaccharide 93
            glucose 91
              multigenerational maternal exposure to hyperglycemia 0
                gestational maternal exposure to hyperglycemia 0
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