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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:troglitazone
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Accession:XCO:0001254 term browser browse the term
Definition:This is any condition in which the main influencing factor is troglitazone, a hypoglycemic agent that was taken off the market due to hepatotoxicity issues. Troglitazone is also an antioxidant, a vasodilator agent, an anticonvulsant, an anticoagulant, an antineoplastic agent, and a long-chain-fatty-acid--CoA ligase inhibitor.
Synonyms:exact_synonym: 5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione
 xref: CHEBI:9753;   MESH:D000077288;   PMID:32119089


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  experimental condition 2376
    therapeutic agent 101
      antineoplastic agent 21
        troglitazone 0
Path 2
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  experimental condition 2376
    chemical 1266
      chemical with specified function 517
        vasoactive chemical 58
          vasodilator 40
            troglitazone 0
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