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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:phenobarbital
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Accession:XCO:0001203 term browser browse the term
Definition:This is any condition in which the main influencing factor is phenobarbital, a barbiturate that acts as a nonselective central nervous system depressant. Phenobarbital potentiates GABA action on GABA-A receptors, modulates chloride currents through receptor channels, and inhibits glutamate induced depolarizations.
Synonyms:exact_synonym: Luminal;   phenobarb;   phenobarbitone
 xref: CID:4763;   MESH:D010634


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  experimental condition 2376
    therapeutic agent 101
      anticonvulsant 16
        phenobarbital 0
          sodium phenobarbital 0
Path 2
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  experimental condition 2376
    chemical 1266
      chemical with specified function 517
        antianxiety agent 0
          phenobarbital 0
            sodium phenobarbital 0
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