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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:nicotine
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Accession:XCO:0001049 term browser browse the term
Definition:This is any condition in which the main influencing factor is nicotine, a highly toxic alkaloid. Nicotine is a racemate composed of equimolar amounts of (R)- and (S)-nicotine. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.
Synonyms:exact_synonym: (R,S)-nicotine;   (RS)-nicotine;   rac-3-(1-methylpyrrolidin-2-yl)pyridine
 xref: PMID:23874651


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  experimental condition 0
    chemical 0
      chemical with specified function 0
        toxic substance 0
          toxin 0
            neurotoxin 0
              nicotine 0
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