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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:immunosuppressive agent
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Accession:XCO:0000636 term browser browse the term
Definition:This is any condition in which the main influencing factor is an agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Synonyms:xref: CHEBI:35705

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Path 1
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  experimental condition 0
    therapeutic agent 0
      immunosuppressive agent 0
        5-fluorouracil 0
        cyclophosphamide 0
        cyclosporine A 0
        dexamethasone + 0
Path 2
Term Annotations click to browse term
  experimental condition 0
    chemical 0
      chemical with specified function 0
        immunosuppressive agent 0
          5-fluorouracil 0
          cyclophosphamide 0
          cyclosporine A 0
          dexamethasone + 0
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