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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:enzyme inhibitor
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Accession:XCO:0000523 term browser browse the term
Definition:This is any condition in which the main influencing factor is a chemical which decreases or interferes with the activity of an enzyme, a protein that catalyzes chemical reactions of other substances without itself being destroyed or altered upon completion of the reactions.


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captopril term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q BpQTLcluster5 Blood pressure QTL cluster 5 IDA RGD PMID:10779487 RGD:68932 NCBI chr 4:62,933,508...114,921,294 JBrowse link
NG-nitroarginine methyl ester term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Bp194 Blood pressure QTL 194 IDA RGD PMID:14532335 RGD:727992 NCBI chr17:2,115,149...34,551,001 JBrowse link
Q Bp251 Blood pressure QTL 251 IDA RGD PMID:12545249 RGD:1303389 NCBI chr 3:14,489,145...121,056,321 JBrowse link
Q Bp255 Blood pressure QTL 255 IDA RGD PMID:12545249 RGD:1303389 NCBI chr 1:191,019,702...246,062,233 JBrowse link
Q Bp259 Blood pressure QTL 259 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 1:210,702,053...260,522,016 JBrowse link
Q Bp260 Blood pressure QTL 260 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 1:151,162,766...225,824,951 JBrowse link
Q Bp261 Blood pressure QTL 261 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 5:90,067,849...128,034,027 JBrowse link
Q Bp262 Blood pressure QTL 262 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 8:27,205,715...99,103,503 JBrowse link
Q Bp263 Blood pressure QTL 263 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 8:93,965,141...123,900,184 JBrowse link
Q Bp264 Blood pressure QTL 264 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 3:14,489,145...121,056,321 JBrowse link
Q Bp265 Blood pressure QTL 265 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 7:83,591,953...134,666,232 JBrowse link
Q Bp266 Blood pressure QTL 266 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 7:83,591,953...134,666,232 JBrowse link
Q Bw47 Body weight QTL 47 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 1:90,508,614...180,359,386 JBrowse link
Q Bw48 Body weight QTL 48 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:157,142,078...211,086,598 JBrowse link
Q Bw49 Body weight QTL 49 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,652...157,142,078 JBrowse link
Q Bw50 Body weight QTL 50 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,652...157,142,078 JBrowse link
Q Bw51 Body weight QTL 51 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 8:51,351,728...107,062,046 JBrowse link
Q Cm38 Cardiac mass QTL 38 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,423...157,142,209 JBrowse link
Q Cm39 Cardiac mass QTL 39 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,423...157,142,209 JBrowse link
Q Cm40 Cardiac mass QTL 40 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 8:27,205,715...99,103,503 JBrowse link
Q Cm41 Cardiac mass QTL 41 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,423...203,928,301 JBrowse link
Q Cm42 Cardiac mass QTL 42 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,423...203,928,301 JBrowse link
Q Kidm22 Kidney mass QTL 22 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 1:210,702,053...240,947,965 JBrowse link
Q Kidm23 Kidney mass QTL 23 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,423...157,142,209 JBrowse link
Q Kidm24 Kidney mass QTL 24 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,423...157,142,209 JBrowse link
Q Kidm25 Kidney mass QTL 25 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 5:90,067,849...128,034,027 JBrowse link
Q Kidm26 Kidney mass QTL 26 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 8:27,205,715...99,103,503 JBrowse link
Q Kidm27 Kidney mass QTL 27 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,423...157,142,209 JBrowse link
Q Kidm28 Kidney mass QTL 28 IDA RGD PMID:14640890 RGD:1303386 NCBI chr 2:25,413,423...157,142,209 JBrowse link
Q Rf10 Renal function QTL 10 IDA RGD PMID:14532335 RGD:727992 NCBI chr 3:161,192,952...169,034,231 JBrowse link
Q Rf23 Renal function QTL 23 IDA RGD PMID:14532335 RGD:727992 NCBI chr15:40,631,268...98,288,169 JBrowse link
Q Rf43 Renal function QTL 43 IDA RGD PMID:11721057 RGD:70849 NCBI chr17:15,330,613...23,017,269 JBrowse link
Q Rf52 Renal function QTL 52 IDA RGD PMID:16541022 RGD:1578626 NCBI chr 1:232,156,370...259,647,894 JBrowse link
Q Rf53 Renal function QTL 53 IDA RGD PMID:16541022 RGD:1578626 NCBI chr 3:56,395,968...161,299,569 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  experimental condition 2376
    chemical 712
      chemical with specified function 517
        inhibitor 40
          enzyme inhibitor 34
            5-aza-2′-deoxycytidine 0
            AMG-8718 0
            DL-α-aminoadipate 0
            JZL184 0
            Medica 16 0
            NB-360 0
            NG-nitroarginine methyl ester + 33
            UNC0638 0
            amprenavir 0
            angiotensin converting enzyme inhibitor + 1
            atorvastatin 0
            caffeine + 0
            diclofenac 0
            dipyridamole 0
            esomeprazole 0
            everolimus 0
            hirudin 0
            imperatorin 0
            indomethacin 0
            letrozole 0
            levofloxacin 0
            lumiracoxib 0
            methimazole 0
            methylene blue 0
            metyrapone + 0
            nabumetone 0
            naproxen 0
            nevirapine 0
            nicotinamide + 0
            pefloxacin 0
            pentoxifylline 0
            perhexiline maleate 0
            protease inhibitor + 0
            protein kinase inhibitor + 0
            proton pump inhibitor + 0
            quinidine + 0
            rolipram 0
            saxagliptin + 0
            semaxanib 0
            tacrine 0
            telmisartan 0
            thapsigargin 0
            tolcapone 0
            troglitazone 0
            trovafloxacin 0
            ximelagatran 0
            zafirlukast 0
paths to the root