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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:insulin
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Accession:XCO:0000245 term browser browse the term
Definition:A protein hormone formed from proinsulin in the beta cells of the pancreatic islets of Langerhans. The major fuel-regulating hormone, it is secreted into the blood in response to a rise in concentration of blood glucose or amino acids. Insulin promotes the storage of glucose and the uptake of amino acids, increases protein and lipid synthesis, and inhibits lipolysis and gluconeogenesis.



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insulin term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Gluco11 Glucose level QTL 11 IDA RGD PMID:15752738 RGD:1357415 NCBI chr 4:85,379,421...167,139,601 JBrowse link
Q Gluco12 Glucose level QTL12 IDA RGD PMID:15752738 RGD:1357415 NCBI chr 4:5,218,392...29,593,287 JBrowse link
Q Gluco16 Glucose level QTL 16 IDA RGD PMID:9171835 RGD:61078 NCBI chr 4:1...30,372,989 JBrowse link
Q Gluco17 Glucose level QTL 17 IDA RGD PMID:9171835 RGD:61078
Q Gluco3 Glucose level QTL 3 IDA RGD PMID:9171835 RGD:61078
Q Gluco4 Glucose level QTL 4 IDA RGD PMID:9171835 RGD:61078 NCBI chr 4:1...33,250,345 JBrowse link
Q Gluco5 Glucose level QTL 5 IDA RGD PMID:9171835 RGD:61078 NCBI chr 4:1...33,250,345 JBrowse link

Related Phenotype Data for Term "insulin" (XCO:0000245)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:

Term paths to the root
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  experimental condition 2376
    chemical 712
      chemical with specified structure 560
        peptide/protein 106
          peptide hormone 15
            insulin 7
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