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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:mutation inducing chemical
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Accession:XCO:0000205 term browser browse the term
Definition:An agent that causes or increases the frequency of permanent, heritable changes in the DNA sequence or chromosomal structure of a cell or organism.
Synonyms:exact_synonym: mutagen
 related_synonym: mutation inducing agent


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1,2-dimethylhydrazine term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Colcr1 Colorectal carcinoma resistance QTL 1 IDA 3.0E-4 4.3 RGD PMID:17510081 RGD:1625309 NCBI chr 4:8,428,551...30,449,094 JBrowse link
Q Colcr2 Colorectal carcinoma resistance QTL 2 IDA 0.0197 6.57 RGD PMID:17510081 RGD:1625309 NCBI chr15:2,315,759...47,315,759 JBrowse link
Q Colcr3 Colorectal carcinoma resistance QTL 3 IDA 7.0E-6 5.02 RGD PMID:17510081 RGD:1625309 NCBI chr18:1...25,022,372 JBrowse link
Q Colcr4 Colorectal carcinoma resistance QTL4 IDA 7.0E-4 3.71 RGD PMID:17510081 RGD:1625309 NCBI chr 6:30,937,632...75,937,632 JBrowse link
Q Colcr5 Colorectal carcinoma resistance QTL 5 IDA 9.0E-4 3.18 RGD PMID:17510081 RGD:1625309 NCBI chr 6:98,944,780...143,944,780 JBrowse link
Q Colcr6 Colorectal carcinoma resistance QTL 6 IDA 0.0126 2.9 RGD PMID:17510081 RGD:1625309 NCBI chr15:83,700,787...108,192,169 JBrowse link
Q Colcr7 Colorectal carcinoma resistance QTL 7 IDA 0.0044 3.35 RGD PMID:17510081 RGD:1625309 NCBI chr17:2,120,843...22,087,569 JBrowse link
Q Colcr8 Colorectal carcinoma resistance QTL 8 IDA 0.0014 3.1 RGD PMID:17510081 RGD:1625309 NCBI chr18:31,990,891...76,990,891 JBrowse link
Q Colcr9 Colorectal carcinoma resistance QTL 9 IDA 0.0024 2.97 RGD PMID:17510081 RGD:1625309 NCBI chr20:1...33,724,594 JBrowse link
Q Colcs1 Colorectal carcinoma susceptibility QTL 1 IDA 0.0055 2.99 RGD PMID:17510081 RGD:1625309 NCBI chr 5:160,071,170...172,129,029 JBrowse link
2-acetamidofluorene term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Hcar1 Hepatocarcinoma resistance QTL 1 IDA 1.0E-4 3.4 RGD PMID:10493520 RGD:619598 NCBI chr10:6,661,118...35,509,383 JBrowse link
Q Hcar10 Hepatocarcinoma resistance QTL 10 IDA 2.9 RGD PMID:12154055 RGD:629566 NCBI chr 8:49,610,204...68,373,388 JBrowse link
Q Hcar11 Hepatocarcinoma resistance QTL 11 IDA 4.4 RGD PMID:12154055 RGD:629566 NCBI chr 6:46,050,607...116,278,722 JBrowse link
Q Hcar12 Hepatocarcinoma resistance QTL 12 IDA 2.6 RGD PMID:12154055 RGD:629566 NCBI chr 3:49,872,657...138,829,559 JBrowse link
Q Hcar13 Hepatocarcinoma resistance QTL 13 IDA 4.3 RGD PMID:15185337 RGD:737884 NCBI chr 4:1...33,538,816 JBrowse link
Q Hcar14 Hepatocarcinoma resistance QTL 14 IDA 4.3 RGD PMID:15185337 RGD:737884 NCBI chr18:57,825,243...85,493,247 JBrowse link
Q Hcar2 Hepatocarcinoma resistance QTL 2 IDA 3.0E-4 3.1 RGD PMID:10493520 RGD:619598 NCBI chr 4:84,349,032...129,349,032 JBrowse link
Q Hcar3 Hepatocarcinoma resistance QTL 3 IDA 5.0E-4 2.9 RGD PMID:10493520 RGD:619598 NCBI chr 8:62,982,864...107,982,864 JBrowse link
Q Hcar9 Hepatocarcinoma resistance QTL 9 IDA 3.7 RGD PMID:12154055 RGD:629566 NCBI chr 4:106,848,959...168,870,974 JBrowse link
Q Hcas1 Hepatocarcinoma susceptibility QTL 1 IDA 0.001 3.9 RGD PMID:10493520 RGD:619598 NCBI chr 7:93,302,009...131,686,183 JBrowse link
Q Hcas2 Hepatocarcinoma susceptibility QTL 2 IDA 1.0E-4 3.0 RGD PMID:10493520 RGD:619598 NCBI chr 1:7,746,118...52,746,118 JBrowse link
Q Hcas3 Hepatocarcinoma susceptibility QTL 3 IDA 4.9 RGD PMID:12154055 RGD:629566 NCBI chr 1:153,679,879...232,414,077 JBrowse link
Q Hcas4 Hepatocarcinoma susceptibility QTL 4 IDA 4.43 RGD PMID:12154055 RGD:629566 NCBI chr16:4,234,212...53,708,481 JBrowse link
Q Hcas5 Hepatocarcinoma susceptibility QTL 5 IDA 3.12 RGD PMID:15185337 RGD:737884 NCBI chr 1:185,857,683...270,518,180 JBrowse link
Q Hcas6 Hepatocarcinoma susceptibility QTL 6 IDA 2.93 RGD PMID:15185337 RGD:737884 NCBI chr14:39,411,170...87,582,095 JBrowse link
Q Hcas7 Hepatocarcinoma susceptibility QTL 7 IDA 2.91 RGD PMID:15185337 RGD:737884 NCBI chr15:2,315,759...53,331,089 JBrowse link
Q Lnnr1 Liver neoplastic nodule remodeling QTL 1 IDA 0.001 3.85 RGD PMID:12672032 RGD:629574 NCBI chr 7:36,178,764...81,178,764 JBrowse link
Q Lnnr2 Liver neoplastic nodule remodeling QTL 2 IDA 5.0E-4 2.9 RGD PMID:12672032 RGD:629574 NCBI chr 1:243,953,669...270,518,180 JBrowse link
Q Lnnr3 Liver neoplastic nodule remodeling QTL 3 IDA 2.94 RGD PMID:15185337 RGD:737884 NCBI chr 2:1...42,977,529 JBrowse link
Q Lnnr4 Liver neoplastic nodule remodeling QTL 4 IDA 3.64 RGD PMID:15185337 RGD:737884 NCBI chr13:1...34,785,618 JBrowse link
Q Lnnr5 Liver neoplastic nodule remodeling QTL 5 IDA 3.29 RGD PMID:15185337 RGD:737884 NCBI chr13:62,424,592...88,113,509 JBrowse link
Q Lnnr6 Liver neoplastic nodule remodeling QTL 6 IDA 3.3 RGD PMID:15185337 RGD:737884 NCBI chr13:65,613,454...109,350,286 JBrowse link
4-nitroquinoline N-oxide term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Tcas10 Tongue tumor susceptibility QTL 10 IDA 3.12 RGD PMID:11429048 RGD:634723 NCBI chr10:31,796,281...76,796,281 JBrowse link
Q Tcas11 Tongue tumor susceptibility QTL 11 IDA 4.12 RGD PMID:16527513 RGD:1578522 NCBI chr 5:51,657,967...166,600,247 JBrowse link
Q Tcas2 Tongue tumor susceptibility QTL 2 IDA 4.93 RGD PMID:11429048 RGD:634723 NCBI chr 1:201,915,593...208,479,939 JBrowse link
Q Tcas3 Tongue tumor susceptibility QTL 3 IDA 6.88 RGD PMID:11429048 RGD:634723 NCBI chr 4:11,706,604...92,690,519 JBrowse link
Q Tcas4 Tongue tumor susceptibility QTL 4 IDA 7.29 RGD PMID:11429048 RGD:634723 NCBI chr14:17,906,726...54,251,504 JBrowse link
Q Tcas5 Tongue tumor susceptibility QTL 5 IDA 10.04 RGD PMID:11429048 RGD:634723
Q Tcas6 Tongue tumor susceptibility QTL 6 IDA 6.85 RGD PMID:11429048 RGD:634723 NCBI chr 1:102,359,314...153,680,016 JBrowse link
Q Tcas7 Tongue tumor susceptibility QTL 7 IDA 0.001 RGD PMID:15876484 RGD:1358147 NCBI chr19:41,722,546...74,246,245 JBrowse link
Q Tcas8 Tongue tumor susceptibility QTL 8 IDA 3.47 RGD PMID:11429048 RGD:634723 NCBI chr 5:15,707,451...60,707,451 JBrowse link
Q Tcas9 Tongue tumor susceptibility QTL 9 IDA 3.29 RGD PMID:11429048 RGD:634723
controlled 4-nitroquinoline N-oxide content drinking water term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Tcas1 Tongue tumor susceptibility QTL 1 IDA 6.08 RGD PMID:9563479 RGD:61091 NCBI chr19:19,220,689...64,220,689 JBrowse link
Q Tcat1 Tongue tumor resistance QTL 1 IDA 3.3 RGD PMID:9563479 RGD:61091 NCBI chr 1:108,680,016...153,680,016 JBrowse link
controlled N-methyl-N'-nitro-N-nitrosoguanidine content drinking water term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Gcr1 Gastric cancer resistance QTL 1 IDA 2.7 RGD PMID:10706129 RGD:69698 NCBI chr 4:103,834,277...148,834,277 JBrowse link
Q Gcr2 Gastric cancer resistance QTL 2 IDA 2.6 RGD PMID:10706129 RGD:69698 NCBI chr 3:29,056,275...47,904,329 JBrowse link
Q Gcr3 Gastric cancer resistance QTL 3 IDA 2.3 RGD PMID:10706129 RGD:69698 NCBI chr16:17,730,818...72,536,785 JBrowse link
Q Gcs1 Gastric cancer susceptibility QTL1 IDA 3.8 RGD PMID:10706129 RGD:69698 NCBI chr15:82,714,037...106,778,197 JBrowse link
controlled N-propyl-N-nitrosourea content drinking water term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Tls1 T-lymphoma susceptibility QTL 1 IDA 0.001 0.0 RGD PMID:10360666 RGD:619600
Q Tls2 T-lymphoma susceptibility QTL 2 IDA 0.001 0.0 RGD PMID:10360666 RGD:619600 NCBI chr 7:82,111,382...132,099,989 JBrowse link
Q Tls3 T-lymphoma susceptibility QTL 3 IDA 1.0E-4 0.0 RGD PMID:10360666 RGD:619600 NCBI chr10:27,587,226...96,099,902 JBrowse link
N-ethyl-N-nitrosourea term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Schws1 Schwannoma susceptibility QTL 1 IDA 0.0041 RGD PMID:16003739 RGD:1559300 NCBI chr10:40,535,708...107,713,808 JBrowse link
Q Schws2 Schwannoma susceptibility QTL 2 IDA 0.029 RGD PMID:16003739 RGD:1559300 NCBI chr 1:153,788,989...198,788,989 JBrowse link
Q Schws3 Schwannoma susceptibility QTL 3 IDA 0.001 RGD PMID:16003739 RGD:1559300 NCBI chr 3:139,299,381...184,299,381 JBrowse link
Q Schws4 Schwannoma susceptibility QTL 4 IDA 0.0078 RGD PMID:16003739 RGD:1559300 NCBI chr 6:78,204,640...123,204,640 JBrowse link
Q Schws5 Schwannoma susceptibility QTL 5 IDA 0.0351 RGD PMID:16003739 RGD:1559300 NCBI chr13:64,497,900...109,350,286 JBrowse link
Q Schws6 Schwannoma susceptibility QTL 6 IDA 0.0069 RGD PMID:16003739 RGD:1559300 NCBI chr15:60,213,984...105,213,984 JBrowse link
Q Schws7 Schwannoma susceptibility QTL 7 IDA 0.0115 RGD PMID:16003739 RGD:1559300
Q Schws8 Schwannoma susceptibility QTL 8 IDA RGD PMID:25303613 RGD:11566050 NCBI chr 6:100,704,576...101,593,851 JBrowse link
Q Schws9 Schwannoma susceptibility QTL 9 IDA RGD PMID:25303613 RGD:11566050 NCBI chr 6:101,593,607...146,593,607 JBrowse link
N-methyl-N-nitrosourea term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Mcs30 Mammary carcinoma susceptibility QTL 30 IDA 8.62 RGD PMID:24023717 RGD:7327193 NCBI chr12:5,633,306...50,633,306 JBrowse link
N-nitrosodiethylamine term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Hcar1 Hepatocarcinoma resistance QTL 1 IDA 1.0E-4 3.4 RGD PMID:10493520 RGD:619598 NCBI chr10:6,661,118...35,509,383 JBrowse link
Q Hcar10 Hepatocarcinoma resistance QTL 10 IDA 2.9 RGD PMID:12154055 RGD:629566 NCBI chr 8:49,610,204...68,373,388 JBrowse link
Q Hcar11 Hepatocarcinoma resistance QTL 11 IDA 4.4 RGD PMID:12154055 RGD:629566 NCBI chr 6:46,050,607...116,278,722 JBrowse link
Q Hcar12 Hepatocarcinoma resistance QTL 12 IDA 2.6 RGD PMID:12154055 RGD:629566 NCBI chr 3:49,872,657...138,829,559 JBrowse link
Q Hcar13 Hepatocarcinoma resistance QTL 13 IDA 4.3 RGD PMID:15185337 RGD:737884 NCBI chr 4:1...33,538,816 JBrowse link
Q Hcar14 Hepatocarcinoma resistance QTL 14 IDA 4.3 RGD PMID:15185337 RGD:737884 NCBI chr18:57,825,243...85,493,247 JBrowse link
Q Hcar2 Hepatocarcinoma resistance QTL 2 IDA 3.0E-4 3.1 RGD PMID:10493520 RGD:619598 NCBI chr 4:84,349,032...129,349,032 JBrowse link
Q Hcar3 Hepatocarcinoma resistance QTL 3 IDA 5.0E-4 2.9 RGD PMID:10493520 RGD:619598 NCBI chr 8:62,982,864...107,982,864 JBrowse link
Q Hcar9 Hepatocarcinoma resistance QTL 9 IDA 3.7 RGD PMID:12154055 RGD:629566 NCBI chr 4:106,848,959...168,870,974 JBrowse link
Q Hcas1 Hepatocarcinoma susceptibility QTL 1 IDA 0.001 3.9 RGD PMID:10493520 RGD:619598 NCBI chr 7:93,302,009...131,686,183 JBrowse link
Q Hcas2 Hepatocarcinoma susceptibility QTL 2 IDA 1.0E-4 3.0 RGD PMID:10493520 RGD:619598 NCBI chr 1:7,746,118...52,746,118 JBrowse link
Q Hcas3 Hepatocarcinoma susceptibility QTL 3 IDA 4.9 RGD PMID:12154055 RGD:629566 NCBI chr 1:153,679,879...232,414,077 JBrowse link
Q Hcas4 Hepatocarcinoma susceptibility QTL 4 IDA 4.43 RGD PMID:12154055 RGD:629566 NCBI chr16:4,234,212...53,708,481 JBrowse link
Q Hcas5 Hepatocarcinoma susceptibility QTL 5 IDA 3.12 RGD PMID:15185337 RGD:737884 NCBI chr 1:185,857,683...270,518,180 JBrowse link
Q Hcas6 Hepatocarcinoma susceptibility QTL 6 IDA 2.93 RGD PMID:15185337 RGD:737884 NCBI chr14:39,411,170...87,582,095 JBrowse link
Q Hcas7 Hepatocarcinoma susceptibility QTL 7 IDA 2.91 RGD PMID:15185337 RGD:737884 NCBI chr15:2,315,759...53,331,089 JBrowse link
Q Hcas8 Hepatocarcinoma susceptibility QTL 8 IDA RGD PMID:17079458 RGD:1599590 NCBI chr16:16,278,184...27,244,292 JBrowse link
Q Lnnr1 Liver neoplastic nodule remodeling QTL 1 IDA 0.001 3.85 RGD PMID:12672032 RGD:629574 NCBI chr 7:36,178,764...81,178,764 JBrowse link
Q Lnnr2 Liver neoplastic nodule remodeling QTL 2 IDA 5.0E-4 2.9 RGD PMID:12672032 RGD:629574 NCBI chr 1:243,953,669...270,518,180 JBrowse link
Q Lnnr3 Liver neoplastic nodule remodeling QTL 3 IDA 2.94 RGD PMID:15185337 RGD:737884 NCBI chr 2:1...42,977,529 JBrowse link
Q Lnnr4 Liver neoplastic nodule remodeling QTL 4 IDA 3.64 RGD PMID:15185337 RGD:737884 NCBI chr13:1...34,785,618 JBrowse link
Q Lnnr5 Liver neoplastic nodule remodeling QTL 5 IDA 3.29 RGD PMID:15185337 RGD:737884 NCBI chr13:62,424,592...88,113,509 JBrowse link
Q Lnnr6 Liver neoplastic nodule remodeling QTL 6 IDA 3.3 RGD PMID:15185337 RGD:737884 NCBI chr13:65,613,454...109,350,286 JBrowse link
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Term Annotations click to browse term
  experimental condition 2376
    chemical 1266
      chemical with specified function 517
        mutation inducing chemical 62
          1,2-dimethylhydrazine 10
          2-acetamidofluorene + 22
          4-nitroquinoline N-oxide + 12
          N-ethyl-N-nitrosourea 9
          N-methyl-N'-nitro-N-nitrosoguanidine + 4
          N-methyl-N-nitrosourea 1
          N-nitrosodiethylamine 23
          N-propyl-N-nitrosourea + 3
          cisplatin + 0
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