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VERTEBRATE TRAIT ONTOLOGY - ANNOTATIONS

The Vertebrate Trait Ontology (VT) is being developed as a collaborative effort between the Rat Genome Database at the Medical College of Wisconsin (RGD, http://rgd.mcw.edu), Mouse Genome Informatics at the Jackson Laboratory (http://www.informatics.jax.org/) and the Animal QTL database at Iowa State University (http://www.animalgenome.org/cgi-bin/QTLdb/index). For more information about this vocabulary, or to request additions or changes, please contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:tumor necrosis factor amount
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Accession:VT:0008752 term browser browse the term
Definition:The proportion, quantity, or volume of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium.
Synonyms:exact_synonym: TNF level;   TNFA level;   cachectin level;   tumor necrosis factor alpha level;   tumor necrosis factor level


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blood tumor necrosis factor amount term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Eae35 Experimental allergic encephalomyelitis QTL 35 IDA RGD PMID:24312603 RGD:8662358 NCBI chr 4:100,834,579...103,761,084 JBrowse link
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  vertebrate trait 2911
    organism trait 1162
      homeostasis trait 700
        blood homeostasis trait 540
          blood molecular composition trait 540
            blood protein amount 57
              immune serum protein amount 11
                cytokine amount 8
                  tumor necrosis factor amount 3
                    blood tumor necrosis factor amount 3
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