blood interleukin-6 amount - Ontology Report

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VERTEBRATE TRAIT ONTOLOGY - ANNOTATIONS

The Vertebrate Trait Ontology (VT) is being developed as a collaborative effort between the Rat Genome Database at the Medical College of Wisconsin (RGD, http://rgd.mcw.edu), Mouse Genome Informatics at the Jackson Laboratory (http://www.informatics.jax.org/) and the Animal QTL database at Iowa State University (http://www.animalgenome.org/cgi-bin/QTLdb/index). For more information about this vocabulary, or to request additions or changes, please contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:	blood interleukin-6 amount	go back to main search page
Accession:	VT:0008595	browse the term
Definition:	The proportion, quantity, or volume in whole blood, serum, or plasma of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts.
Synonyms:	related_synonym:	circulating B-cell differentiation factor level; circulating B-cell differentiation factor-2 level; circulating B-cell stimulatory factor 2 level; circulating BSF-2 level; circulating IFN-beta 2 level; circulating IL-6 level; circulating IL6 level; circulating MGI-2 level; circulating hepatocyte-stimulating factor level; circulating hybridoma growth factor level; circulating interleukin-6 level; circulating myeloid differentiation-inducing protein level; circulating plasmacytoma growth factor level

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QTL (3) Strains (2)

blood interleukin-6 amount

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Apr3

Acute phase response QTL 3

RGD

NCBI chr10:15,275,955...60,275,955

Acute phase response QTL 5

RGD

NCBI chr12:1...44,503,507

Acute phase response QTL 6

RGD

NCBI chr14:1...41,131,407

Term paths to the root

Path 1
Term	Annotations
vertebrate trait	2911
organism trait	1162
homeostasis trait	700
blood homeostasis trait	540
blood molecular composition trait	540
blood protein amount	57
blood interleukin amount	5
blood interleukin-6 amount	5
Path 2
Term	Annotations
vertebrate trait	2911
organism trait	1162
homeostasis trait	700
molecule homeostasis trait	367
protein amount	184
blood protein amount	57
immune serum protein amount	11
cytokine amount	8
interleukin amount	5
blood interleukin amount	5
blood interleukin-6 amount	5

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