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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:antineoplastic drug pathway
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Accession:PW:0002367 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs used in the treatment of various cancers. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.


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aromatase inhibitor pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO RGD PMID:18695261 RGD:5130880 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
axitinib pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt1 FMS-like tyrosine kinase 1 ISO RGD PMID:22170007 RGD:6907361 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Flt4 FMS-like tyrosine kinase 4 ISO RGD PMID:22170007 RGD:6907361 NCBI chr11:49,500,506...49,543,566
Ensembl chr11:49,500,090...49,543,566 		JBrowse link
G Kdr kinase insert domain protein receptor ISO RGD PMID:22170007 RGD:6907361 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
axitinib pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO RGD PMID:22170007 RGD:6907361 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO RGD PMID:22170007 RGD:6907361 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO RGD PMID:22170007 RGD:6907361 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO RGD PMID:22170007 RGD:6907361 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO RGD PMID:22170007 RGD:6907361 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
bevacizumab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt1 FMS-like tyrosine kinase 1 ISO SMPDB SMP:00420 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Kdr kinase insert domain protein receptor ISO SMPDB SMP:00420 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO SMPDB SMP:00420 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
capecitabine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cda cytidine deaminase ISO SMPDB SMP:00469 NCBI chr 4:138,065,839...138,095,623
Ensembl chr 4:138,065,735...138,095,303 		JBrowse link
G Ces1d carboxylesterase 1D ISO SMPDB SMP:00469 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 ISO SMPDB SMP:00469 NCBI chr 7:80,763,017...80,820,164
Ensembl chr 7:80,764,547...80,820,164 		JBrowse link
G Tymp thymidine phosphorylase ISO SMPDB SMP:00469 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242 		JBrowse link
G Tyms thymidylate synthase ISO SMPDB SMP:00469 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
capecitabine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cda cytidine deaminase ISO SMPDB SMP:00607 NCBI chr 4:138,065,839...138,095,623
Ensembl chr 4:138,065,735...138,095,303 		JBrowse link
G Ces1d carboxylesterase 1D ISO SMPDB SMP:00607 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 ISO SMPDB SMP:00607 NCBI chr 7:80,763,017...80,820,164
Ensembl chr 7:80,764,547...80,820,164 		JBrowse link
G Tymp thymidine phosphorylase ISO SMPDB SMP:00607 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242 		JBrowse link
G Tyms thymidylate synthase ISO SMPDB SMP:00607 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
cetuximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO SMPDB SMP:00474 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
cisplatin drug pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atox1 antioxidant 1 copper chaperone ISO RGD PMID:23936210 RGD:8548474 NCBI chr11:55,337,463...55,352,034
Ensembl chr11:55,337,467...55,352,065 		JBrowse link
G Atp7a ATPase, copper transporting, alpha polypeptide ISO RGD PMID:22796517 RGD:8548473 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532 		JBrowse link
G Atp7b ATPase, copper transporting, beta polypeptide ISO RGD PMID:22796517 RGD:8548473 NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321 		JBrowse link
G Hmgb1 high mobility group box 1 ISO RGD PMID:20046924 RGD:8548475 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Slc31a1 solute carrier family 31, member 1 ISO RGD PMID:22796517 PMID:23123662 RGD:8548473, RGD:8549769 NCBI chr 4:62,278,821...62,310,006
Ensembl chr 4:62,278,964...62,310,006 		JBrowse link
G Ssrp1 structure specific recognition protein 1 ISO RGD PMID:20046924 RGD:8548475 NCBI chr 2:84,867,519...84,877,453
Ensembl chr 2:84,867,578...84,877,453 		JBrowse link
G Tbp TATA box binding protein ISO RGD PMID:20046924 RGD:8548475 NCBI chr17:15,720,150...15,737,689
Ensembl chr17:15,720,150...15,748,641 		JBrowse link
G Ubtf upstream binding transcription factor, RNA polymerase I ISO RGD PMID:20046924 RGD:8548475 NCBI chr11:102,195,393...102,214,738
Ensembl chr11:102,195,386...102,210,568 		JBrowse link
G Ybx1 Y box protein 1 ISO RGD PMID:20046924 RGD:8548475 NCBI chr 4:119,134,524...119,153,462
Ensembl chr 4:119,135,178...119,151,801 		JBrowse link
cyclophosphamide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 ISO SMPDB SMP:00447 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 ISO SMPDB SMP:00447 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247 		JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 ISO SMPDB SMP:00447 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 ISO SMPDB SMP:00447 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00447 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO SMPDB SMP:00447 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO SMPDB SMP:00447 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO SMPDB SMP:00447 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO SMPDB SMP:00447 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00447 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 ISO SMPDB SMP:00447 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
cyclophosphamide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 ISO SMPDB SMP:00604 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 ISO SMPDB SMP:00604 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247 		JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 ISO SMPDB SMP:00604 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 ISO SMPDB SMP:00604 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00604 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO SMPDB SMP:00604 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO SMPDB SMP:00604 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO SMPDB SMP:00604 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO SMPDB SMP:00604 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00604 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 ISO SMPDB SMP:00604 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
docetaxel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00435 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 ISO SMPDB SMP:00435 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO SMPDB SMP:00435 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO SMPDB SMP:00435 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 ISO SMPDB SMP:00435 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372 		JBrowse link
G Tuba1b tubulin, alpha 1B ISO SMPDB SMP:00435 NCBI chr15:98,829,310...98,832,271
Ensembl chr15:98,829,306...98,832,446 		JBrowse link
G Tubb1 tubulin, beta 1 class VI ISO SMPDB SMP:00435 NCBI chr 2:174,292,388...174,300,173
Ensembl chr 2:174,292,488...174,299,675 		JBrowse link
doxorubicin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Top2a topoisomerase (DNA) II alpha ISO RGD PMID:25895646 RGD:10395260 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Top2b topoisomerase (DNA) II beta ISO RGD PMID:25895646 RGD:10395260 NCBI chr14:6,038,976...6,104,585
Ensembl chr14:6,034,301...6,104,584 		JBrowse link
doxorubicin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 ISO SMPDB SMP:00650 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 ISO RGD PMID:21048526 RGD:10395261 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 ISO SMPDB
RGD		 PMID:21048526 PMID:19442138 SMP:00650, RGD:10395261, RGD:10395262 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877 		JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 ISO SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO SMPDB
RGD		 PMID:21048526 PMID:19442138 SMP:00650, RGD:10395261, RGD:10395262 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393 		JBrowse link
G Cbr3 carbonyl reductase 3 ISO SMPDB
RGD		 PMID:21048526 PMID:19442138 SMP:00650, RGD:10395261, RGD:10395262 NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 ISO SMPDB SMP:00650 NCBI chr 1:171,062,426...171,078,956
Ensembl chr 1:171,062,422...171,078,957 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 ISO SMPDB SMP:00650 NCBI chr 2:90,724,971...90,735,065
Ensembl chr 2:90,724,978...90,735,171 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 ISO SMPDB SMP:00650 NCBI chr10:80,084,939...80,092,628
Ensembl chr10:80,084,955...80,092,628 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO SMPDB
RGD		 PMID:19442138 SMP:00650, RGD:10395262 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 ISO SMPDB
RGD		 PMID:19442138 SMP:00650, RGD:10395262 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO SMPDB SMP:00650 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Ralbp1 ralA binding protein 1 ISO SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr17:66,155,410...66,192,750
Ensembl chr17:66,155,413...66,192,793 		JBrowse link
G Slc22a16 solute carrier family 22 (organic cation transporter), member 16 ISO SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr10:40,446,317...40,480,128
Ensembl chr10:40,446,332...40,480,128 		JBrowse link
G Xdh xanthine dehydrogenase ISO SMPDB
RGD		 PMID:19442138 SMP:00650, RGD:10395262 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
erlotinib pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00472 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO SMPDB SMP:00472 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Egfr epidermal growth factor receptor ISO SMPDB SMP:00472 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
etoposide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00442 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 ISO SMPDB SMP:00442 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00442 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00442 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00442 NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00442 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 ISO SMPDB SMP:00442 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa5 heat shock protein 5 ISO SMPDB SMP:00442 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hyou1 hypoxia up-regulated 1 ISO SMPDB SMP:00442 NCBI chr 9:44,290,840...44,303,662
Ensembl chr 9:44,290,787...44,303,666 		JBrowse link
G Mpo myeloperoxidase ISO SMPDB SMP:00442 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Pdia2 protein disulfide isomerase associated 2 ISO SMPDB SMP:00442 NCBI chr17:26,414,973...26,418,108
Ensembl chr17:26,414,973...26,418,061 		JBrowse link
G Pdia4 protein disulfide isomerase associated 4 ISO SMPDB SMP:00442 NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364 		JBrowse link
G Pdia6 protein disulfide isomerase associated 6 ISO SMPDB SMP:00442 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771 		JBrowse link
G Ppib peptidylprolyl isomerase B ISO SMPDB SMP:00442 NCBI chr 9:65,967,451...65,973,911
Ensembl chr 9:65,967,504...65,973,905 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00442 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00442 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 ISO SMPDB SMP:00442 NCBI chr16:16,948,002...16,950,247
Ensembl chr16:16,948,002...16,950,247 		JBrowse link
G Top2a topoisomerase (DNA) II alpha ISO SMPDB SMP:00442 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Top2b topoisomerase (DNA) II beta ISO SMPDB SMP:00442 NCBI chr14:6,038,976...6,104,585
Ensembl chr14:6,034,301...6,104,584 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO SMPDB SMP:00442 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
etoposide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00601 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 ISO SMPDB SMP:00601 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00601 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00601 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00601 NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00601 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 ISO SMPDB SMP:00601 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa5 heat shock protein 5 ISO SMPDB SMP:00601 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hyou1 hypoxia up-regulated 1 ISO SMPDB SMP:00601 NCBI chr 9:44,290,840...44,303,662
Ensembl chr 9:44,290,787...44,303,666 		JBrowse link
G Mpo myeloperoxidase ISO SMPDB SMP:00601 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Pdia2 protein disulfide isomerase associated 2 ISO SMPDB SMP:00601 NCBI chr17:26,414,973...26,418,108
Ensembl chr17:26,414,973...26,418,061 		JBrowse link
G Pdia4 protein disulfide isomerase associated 4 ISO SMPDB SMP:00601 NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364 		JBrowse link
G Pdia6 protein disulfide isomerase associated 6 ISO SMPDB SMP:00601 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771 		JBrowse link
G Ppib peptidylprolyl isomerase B ISO SMPDB SMP:00601 NCBI chr 9:65,967,451...65,973,911
Ensembl chr 9:65,967,504...65,973,905 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00601 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00601 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 ISO SMPDB SMP:00601 NCBI chr16:16,948,002...16,950,247
Ensembl chr16:16,948,002...16,950,247 		JBrowse link
G Top2a topoisomerase (DNA) II alpha ISO SMPDB SMP:00601 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Top2b topoisomerase (DNA) II beta ISO SMPDB SMP:00601 NCBI chr14:6,038,976...6,104,585
Ensembl chr14:6,034,301...6,104,584 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO SMPDB SMP:00601 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
gefitinib pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO SMPDB
RGD		 PMID:19733976 SMP:00473, RGD:5135288 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
gefitinib pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO RGD PMID:19733976 RGD:5135288 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO RGD PMID:19733976 RGD:5135288 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO RGD PMID:19733976 RGD:5135288 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 ISO RGD PMID:19733976 RGD:5135288 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO RGD PMID:19733976 RGD:5135288 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
gemcitabine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 ISO SMPDB SMP:00446 NCBI chr 4:114,817,810...114,844,425
Ensembl chr 4:114,816,533...114,844,438 		JBrowse link
G Ctps1 cytidine 5'-triphosphate synthase 1 ISO SMPDB SMP:00446 NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473 		JBrowse link
G Dck deoxycytidine kinase ISO SMPDB SMP:00446 NCBI chr 5:88,912,872...88,931,136
Ensembl chr 5:88,912,855...88,931,140 		JBrowse link
G Dctd dCMP deaminase ISO SMPDB SMP:00446 NCBI chr 8:48,552,127...48,594,702
Ensembl chr 8:48,552,127...48,606,268 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO SMPDB SMP:00446 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347 		JBrowse link
G Nt5c 5',3'-nucleotidase, cytosolic ISO SMPDB SMP:00446 NCBI chr11:115,381,251...115,382,659
Ensembl chr11:115,381,246...115,382,688 		JBrowse link
G Rrm1 ribonucleotide reductase M1 ISO SMPDB SMP:00446 NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978 		JBrowse link
G Rrm2 ribonucleotide reductase M2 ISO SMPDB SMP:00446 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145 		JBrowse link
G Rrm2b ribonucleotide reductase M2 B (TP53 inducible) ISO SMPDB SMP:00446 NCBI chr15:37,924,196...37,961,562
Ensembl chr15:37,924,196...37,961,562 		JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 ISO SMPDB SMP:00446 NCBI chr 7:80,763,017...80,820,164
Ensembl chr 7:80,764,547...80,820,164 		JBrowse link
G Slc28a3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 ISO SMPDB SMP:00446 NCBI chr13:58,701,121...58,758,691
Ensembl chr13:58,693,213...58,758,691 		JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 ISO SMPDB SMP:00446 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532 		JBrowse link
G Tyms thymidylate synthase ISO SMPDB SMP:00446 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
gemcitabine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 ISO SMPDB SMP:00603 NCBI chr 4:114,817,810...114,844,425
Ensembl chr 4:114,816,533...114,844,438 		JBrowse link
G Ctps1 cytidine 5'-triphosphate synthase 1 ISO SMPDB SMP:00603 NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473 		JBrowse link
G Dck deoxycytidine kinase ISO SMPDB SMP:00603 NCBI chr 5:88,912,872...88,931,136
Ensembl chr 5:88,912,855...88,931,140 		JBrowse link
G Dctd dCMP deaminase ISO SMPDB SMP:00603 NCBI chr 8:48,552,127...48,594,702
Ensembl chr 8:48,552,127...48,606,268 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO SMPDB SMP:00603 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347 		JBrowse link
G Nt5c 5',3'-nucleotidase, cytosolic ISO SMPDB SMP:00603 NCBI chr11:115,381,251...115,382,659
Ensembl chr11:115,381,246...115,382,688 		JBrowse link
G Rrm1 ribonucleotide reductase M1 ISO SMPDB SMP:00603 NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978 		JBrowse link
G Rrm2 ribonucleotide reductase M2 ISO SMPDB SMP:00603 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145 		JBrowse link
G Rrm2b ribonucleotide reductase M2 B (TP53 inducible) ISO SMPDB SMP:00603 NCBI chr15:37,924,196...37,961,562
Ensembl chr15:37,924,196...37,961,562 		JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 ISO SMPDB SMP:00603 NCBI chr 7:80,763,017...80,820,164
Ensembl chr 7:80,764,547...80,820,164 		JBrowse link
G Slc28a3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 ISO SMPDB SMP:00603 NCBI chr13:58,701,121...58,758,691
Ensembl chr13:58,693,213...58,758,691 		JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 ISO SMPDB SMP:00603 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532 		JBrowse link
G Tyms thymidylate synthase ISO SMPDB SMP:00603 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
ifosfamide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 ISO SMPDB SMP:00448 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 ISO SMPDB SMP:00448 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247 		JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 ISO SMPDB SMP:00448 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 ISO SMPDB SMP:00448 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00448 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO SMPDB SMP:00448 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO SMPDB SMP:00448 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO SMPDB SMP:00448 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00448 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00448 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
ifosfamide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 ISO SMPDB SMP:00605 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 ISO SMPDB SMP:00605 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247 		JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 ISO SMPDB SMP:00605 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 ISO SMPDB SMP:00605 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00605 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO SMPDB SMP:00605 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO SMPDB SMP:00605 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO SMPDB SMP:00605 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00605 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00605 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
irinotecan pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00433 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 ISO SMPDB SMP:00433 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO SMPDB SMP:00433 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO SMPDB SMP:00433 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Bche butyrylcholinesterase ISO SMPDB SMP:00433 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Ces1d carboxylesterase 1D ISO SMPDB SMP:00433 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Ces2h carboxylesterase 2H ISO SMPDB SMP:00433 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00433 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00433 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00433 NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00433 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 ISO SMPDB SMP:00433 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa5 heat shock protein 5 ISO SMPDB SMP:00433 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hyou1 hypoxia up-regulated 1 ISO SMPDB SMP:00433 NCBI chr 9:44,290,840...44,303,662
Ensembl chr 9:44,290,787...44,303,666 		JBrowse link
G Pdia2 protein disulfide isomerase associated 2 ISO SMPDB SMP:00433 NCBI chr17:26,414,973...26,418,108
Ensembl chr17:26,414,973...26,418,061 		JBrowse link
G Pdia4 protein disulfide isomerase associated 4 ISO SMPDB SMP:00433 NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364 		JBrowse link
G Pdia6 protein disulfide isomerase associated 6 ISO SMPDB SMP:00433 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771 		JBrowse link
G Ppib peptidylprolyl isomerase B ISO SMPDB SMP:00433 NCBI chr 9:65,967,451...65,973,911
Ensembl chr 9:65,967,504...65,973,905 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 ISO SMPDB SMP:00433 NCBI chr16:16,948,002...16,950,247
Ensembl chr16:16,948,002...16,950,247 		JBrowse link
G Top1 topoisomerase (DNA) I ISO SMPDB SMP:00433 NCBI chr 2:160,487,901...160,564,684
Ensembl chr 2:160,487,808...160,564,684 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO SMPDB SMP:00433 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 ISO SMPDB SMP:00433 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 ISO SMPDB SMP:00433 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
irinotecan pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00600 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 ISO SMPDB SMP:00600 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO SMPDB SMP:00600 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO SMPDB SMP:00600 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Bche butyrylcholinesterase ISO SMPDB SMP:00600 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Ces1d carboxylesterase 1D ISO SMPDB SMP:00600 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Ces2h carboxylesterase 2H ISO SMPDB SMP:00600 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00600 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00600 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00600 NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00600 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 ISO SMPDB SMP:00600 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa5 heat shock protein 5 ISO SMPDB SMP:00600 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hyou1 hypoxia up-regulated 1 ISO SMPDB SMP:00600 NCBI chr 9:44,290,840...44,303,662
Ensembl chr 9:44,290,787...44,303,666 		JBrowse link
G Pdia2 protein disulfide isomerase associated 2 ISO SMPDB SMP:00600 NCBI chr17:26,414,973...26,418,108
Ensembl chr17:26,414,973...26,418,061 		JBrowse link
G Pdia4 protein disulfide isomerase associated 4 ISO SMPDB SMP:00600 NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364 		JBrowse link
G Pdia6 protein disulfide isomerase associated 6 ISO SMPDB SMP:00600 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771 		JBrowse link
G Ppib peptidylprolyl isomerase B ISO SMPDB SMP:00600 NCBI chr 9:65,967,451...65,973,911
Ensembl chr 9:65,967,504...65,973,905 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 ISO SMPDB SMP:00600 NCBI chr16:16,948,002...16,950,247
Ensembl chr16:16,948,002...16,950,247 		JBrowse link
G Top1 topoisomerase (DNA) I ISO SMPDB SMP:00600 NCBI chr 2:160,487,901...160,564,684
Ensembl chr 2:160,487,808...160,564,684 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO SMPDB SMP:00600 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 ISO SMPDB SMP:00600 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 ISO SMPDB SMP:00600 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
mercaptopurine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP-binding cassette, sub-family C member 4 ISO SMPDB SMP:00428 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 ISO SMPDB SMP:00428 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144 		JBrowse link
G Ada adenosine deaminase ISO SMPDB SMP:00428 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159 		JBrowse link
G Adcy10 adenylate cyclase 10 ISO SMPDB SMP:00428 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
G Adk adenosine kinase ISO SMPDB SMP:00428 NCBI chr14:21,102,622...21,498,637
Ensembl chr14:21,102,642...21,498,637 		JBrowse link
G Adsl adenylosuccinate lyase ISO SMPDB SMP:00428 NCBI chr15:80,832,691...80,855,148
Ensembl chr15:80,832,691...80,855,147 		JBrowse link
G Adss2 adenylosuccinate synthase 2 ISO SMPDB SMP:00428 NCBI chr 1:177,590,742...177,624,064
Ensembl chr 1:177,590,528...177,624,077 		JBrowse link
G Ak1 adenylate kinase 1 ISO SMPDB SMP:00428 NCBI chr 2:32,511,770...32,525,070
Ensembl chr 2:32,511,770...32,525,070 		JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 ISO SMPDB SMP:00428 NCBI chr 3:102,981,330...103,007,038
Ensembl chr 3:102,981,330...103,007,036 		JBrowse link
G Aox1 aldehyde oxidase 1 ISO SMPDB SMP:00428 NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572 		JBrowse link
G Aprt adenine phosphoribosyl transferase ISO SMPDB SMP:00428 NCBI chr 8:123,301,376...123,303,646
Ensembl chr 8:123,301,374...123,303,648 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 ISO SMPDB SMP:00428 NCBI chr19:32,649,958...32,717,187
Ensembl chr19:32,649,038...32,717,186 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO SMPDB SMP:00428 NCBI chr 1:71,596,315...71,618,562
Ensembl chr 1:71,596,309...71,618,790 		JBrowse link
G Dguok deoxyguanosine kinase ISO SMPDB SMP:00428 NCBI chr 6:83,457,199...83,483,887
Ensembl chr 6:83,457,199...83,483,951 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 ISO SMPDB SMP:00428 NCBI chr12:84,420,649...84,455,803
Ensembl chr12:84,420,631...84,455,803 		JBrowse link
G Entpd8 ectonucleoside triphosphate diphosphohydrolase 8 ISO SMPDB SMP:00428 NCBI chr 2:24,969,308...24,975,731
Ensembl chr 2:24,970,316...24,975,728 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase ISO SMPDB SMP:00428 NCBI chr16:91,418,283...91,444,505
Ensembl chr16:91,418,074...91,443,840 		JBrowse link
G Gda guanine deaminase ISO SMPDB SMP:00428 NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809 		JBrowse link
G Gmpr guanosine monophosphate reductase ISO SMPDB SMP:00428 NCBI chr13:45,660,905...45,699,862
Ensembl chr13:45,660,920...45,707,276 		JBrowse link
G Gmps guanine monophosphate synthetase ISO SMPDB SMP:00428 NCBI chr 3:63,871,054...63,928,975
Ensembl chr 3:63,883,527...63,930,000 		JBrowse link
G Gucy1a2 guanylate cyclase 1, soluble, alpha 2 ISO SMPDB SMP:00428 NCBI chr 9:3,532,349...3,905,791
Ensembl chr 9:3,532,778...3,894,736 		JBrowse link
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 ISO SMPDB SMP:00428 NCBI chr 3:81,939,311...81,982,018
Ensembl chr 3:81,939,313...81,981,996 		JBrowse link
G Guk1 guanylate kinase 1 ISO SMPDB SMP:00428 NCBI chr11:59,074,696...59,083,068
Ensembl chr11:59,074,701...59,083,069 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO SMPDB SMP:00428 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 ISO SMPDB SMP:00428 NCBI chr 6:29,200,435...29,216,363
Ensembl chr 6:29,200,433...29,216,363 		JBrowse link
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) ISO SMPDB SMP:00428 NCBI chr 2:130,506,702...130,523,534
Ensembl chr 2:130,509,530...130,523,534 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 ISO SMPDB SMP:00428 NCBI chr 9:109,661,830...109,672,042
Ensembl chr 9:109,661,817...109,672,184 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II ISO SMPDB SMP:00428 NCBI chr19:46,873,829...47,003,613
Ensembl chr19:46,871,756...47,003,592 		JBrowse link
G Nudt2 nudix hydrolase 2 ISO SMPDB SMP:00428 NCBI chr 4:41,465,085...41,480,926
Ensembl chr 4:41,465,151...41,480,926 		JBrowse link
G Nudt5 nudix hydrolase 5 ISO SMPDB SMP:00428 NCBI chr 2:5,849,839...5,875,631
Ensembl chr 2:5,849,830...5,876,706 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase ISO SMPDB SMP:00428 NCBI chr 5:77,099,149...77,115,356
Ensembl chr 5:77,099,154...77,115,356 		JBrowse link
G Pde10a phosphodiesterase 10A ISO SMPDB SMP:00428 NCBI chr17:8,742,719...9,205,480
Ensembl chr17:8,744,204...9,205,480 		JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific ISO SMPDB SMP:00428 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995 		JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) ISO SMPDB SMP:00428 NCBI chr11:68,876,527...68,899,286
Ensembl chr11:68,876,523...68,899,286 		JBrowse link
G Pnp2 purine-nucleoside phosphorylase 2 ISO SMPDB SMP:00428 NCBI chr14:51,193,598...51,202,206
Ensembl chr14:51,193,449...51,202,206 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO SMPDB SMP:00428 NCBI chr 5:77,061,096...77,099,425
Ensembl chr 5:77,061,096...77,099,425 		JBrowse link
G Prps1l1 phosphoribosyl pyrophosphate synthetase 1-like 1 ISO SMPDB SMP:00428 NCBI chr12:35,034,760...35,036,435
Ensembl chr12:35,034,760...35,036,435 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO SMPDB SMP:00428 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rrm1 ribonucleotide reductase M1 ISO SMPDB SMP:00428 NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978 		JBrowse link
G Rrm2 ribonucleotide reductase M2 ISO SMPDB SMP:00428 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145 		JBrowse link
G Slc28a2 solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 ISO SMPDB SMP:00428 NCBI chr 2:122,256,836...122,291,633
Ensembl chr 2:122,256,958...122,291,618 		JBrowse link
G Slc28a3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 ISO SMPDB SMP:00428 NCBI chr13:58,701,121...58,758,691
Ensembl chr13:58,693,213...58,758,691 		JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 ISO SMPDB SMP:00428 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532 		JBrowse link
G Slc29a2 solute carrier family 29 (nucleoside transporters), member 2 ISO SMPDB SMP:00428 NCBI chr19:5,069,085...5,082,000
Ensembl chr19:5,073,888...5,082,000 		JBrowse link
G Tpmt thiopurine methyltransferase ISO SMPDB SMP:00428 NCBI chr13:47,175,463...47,196,833
Ensembl chr13:47,175,958...47,198,213 		JBrowse link
G Txn1 thioredoxin 1 ISO SMPDB SMP:00428 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411 		JBrowse link
G Xdh xanthine dehydrogenase ISO SMPDB SMP:00428 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
mercaptopurine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP-binding cassette, sub-family C member 4 ISO SMPDB SMP:00609 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 ISO SMPDB SMP:00609 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144 		JBrowse link
G Adk adenosine kinase ISO SMPDB SMP:00609 NCBI chr14:21,102,622...21,498,637
Ensembl chr14:21,102,642...21,498,637 		JBrowse link
G Aox1 aldehyde oxidase 1 ISO SMPDB SMP:00609 NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572 		JBrowse link
G Gmps guanine monophosphate synthetase ISO SMPDB SMP:00609 NCBI chr 3:63,871,054...63,928,975
Ensembl chr 3:63,883,527...63,930,000 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO SMPDB SMP:00609 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 ISO SMPDB SMP:00609 NCBI chr 6:29,200,435...29,216,363
Ensembl chr 6:29,200,433...29,216,363 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO SMPDB SMP:00609 NCBI chr 5:77,061,096...77,099,425
Ensembl chr 5:77,061,096...77,099,425 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO SMPDB SMP:00609 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Slc28a2 solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 ISO SMPDB SMP:00609 NCBI chr 2:122,256,836...122,291,633
Ensembl chr 2:122,256,958...122,291,618 		JBrowse link
G Slc28a3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 ISO SMPDB SMP:00609 NCBI chr13:58,701,121...58,758,691
Ensembl chr13:58,693,213...58,758,691 		JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 ISO SMPDB SMP:00609 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532 		JBrowse link
G Slc29a2 solute carrier family 29 (nucleoside transporters), member 2 ISO SMPDB SMP:00609 NCBI chr19:5,069,085...5,082,000
Ensembl chr19:5,073,888...5,082,000 		JBrowse link
G Tpmt thiopurine methyltransferase ISO SMPDB SMP:00609 NCBI chr13:47,175,463...47,196,833
Ensembl chr13:47,175,958...47,198,213 		JBrowse link
G Xdh xanthine dehydrogenase ISO SMPDB SMP:00609 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
methotrexate pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 ISO SMPDB SMP:00432 NCBI chr 6:90,527,751...90,576,153
Ensembl chr 6:90,463,409...90,577,185 		JBrowse link
G Dhfr dihydrofolate reductase ISO SMPDB SMP:00432 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561 		JBrowse link
G Fpgs folylpolyglutamyl synthetase ISO SMPDB SMP:00432 NCBI chr 2:32,572,621...32,594,163
Ensembl chr 2:32,572,621...32,594,157 		JBrowse link
G Ftcd formiminotransferase cyclodeaminase ISO SMPDB SMP:00432 NCBI chr10:76,411,482...76,426,172
Ensembl chr10:76,411,482...76,426,172 		JBrowse link
G Ggh gamma-glutamyl hydrolase ISO SMPDB SMP:00432 NCBI chr 4:20,041,963...20,066,111
Ensembl chr 4:20,042,052...20,066,750 		JBrowse link
G Mtfmt mitochondrial methionyl-tRNA formyltransferase ISO SMPDB SMP:00432 NCBI chr 9:65,343,064...65,360,336
Ensembl chr 9:65,343,064...65,360,336 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase ISO SMPDB SMP:00432 NCBI chr12:76,301,180...76,366,594
Ensembl chr12:76,302,072...76,366,577 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like ISO SMPDB SMP:00432 NCBI chr10:3,918,282...4,117,081
Ensembl chr10:3,923,118...4,117,081 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase ISO SMPDB SMP:00432 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO SMPDB SMP:00432 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008 		JBrowse link
G Mthfs 5, 10-methenyltetrahydrofolate synthetase ISO SMPDB SMP:00432 NCBI chr 9:89,093,243...89,122,278
Ensembl chr 9:89,092,729...89,259,766 		JBrowse link
G Slc46a1 solute carrier family 46, member 1 ISO SMPDB SMP:00432 NCBI chr11:78,356,527...78,362,771
Ensembl chr11:78,356,523...78,362,885 		JBrowse link
panitumumab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO SMPDB SMP:00475 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
sorafenib pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00648 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO SMPDB SMP:00648 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO SMPDB SMP:00648 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO SMPDB SMP:00648 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00648 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00648 NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00648 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 ISO SMPDB SMP:00648 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa5 heat shock protein 5 ISO SMPDB SMP:00648 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hyou1 hypoxia up-regulated 1 ISO SMPDB SMP:00648 NCBI chr 9:44,290,840...44,303,662
Ensembl chr 9:44,290,787...44,303,666 		JBrowse link
G Pdia2 protein disulfide isomerase associated 2 ISO SMPDB SMP:00648 NCBI chr17:26,414,973...26,418,108
Ensembl chr17:26,414,973...26,418,061 		JBrowse link
G Pdia4 protein disulfide isomerase associated 4 ISO SMPDB SMP:00648 NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364 		JBrowse link
G Pdia6 protein disulfide isomerase associated 6 ISO SMPDB SMP:00648 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771 		JBrowse link
G Ppib peptidylprolyl isomerase B ISO SMPDB SMP:00648 NCBI chr 9:65,967,451...65,973,911
Ensembl chr 9:65,967,504...65,973,905 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 ISO SMPDB SMP:00648 NCBI chr16:16,948,002...16,950,247
Ensembl chr16:16,948,002...16,950,247 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO SMPDB SMP:00648 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 ISO SMPDB SMP:00648 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
tamoxifen pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00471 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 ISO SMPDB SMP:00471 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00471 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00471 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) ISO SMPDB
RGD		 PMID:19629072 SMP:00471, RGD:5130191 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO RGD PMID:19629072 RGD:5130191 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Fmo1 flavin containing monooxygenase 1 ISO SMPDB SMP:00471 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179 		JBrowse link
G Fmo3 flavin containing monooxygenase 3 ISO SMPDB SMP:00471 NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO RGD PMID:16822624 RGD:5130718 NCBI chr 2:165,834,557...165,915,162
Ensembl chr 2:165,834,545...165,915,162 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 ISO RGD PMID:16822624 RGD:5130718 NCBI chr11:62,207,132...62,348,200
Ensembl chr11:62,207,252...62,349,367 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 ISO RGD PMID:16822624 RGD:5130718 NCBI chr 5:125,094,217...125,256,302
Ensembl chr 5:125,094,217...125,256,283 		JBrowse link
G Phb2 prohibitin 2 ISO RGD PMID:16822624 RGD:5130718 NCBI chr 6:124,689,252...124,693,908
Ensembl chr 6:124,689,299...124,693,913 		JBrowse link
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 ISO SMPDB SMP:00471 NCBI chr 7:126,272,042...126,289,615
Ensembl chr 7:126,272,037...126,275,604 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 ISO SMPDB SMP:00471 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 ISO SMPDB SMP:00471 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719 		JBrowse link
tamoxifen pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO RGD PMID:21148080 RGD:5130188 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO RGD PMID:12971802 RGD:5129544 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO RGD PMID:12971802 RGD:5129544 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00606 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO RGD PMID:12971802 RGD:5129544 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO RGD PMID:12971802 RGD:5129544 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO RGD PMID:12971802 RGD:5129544 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 ISO SMPDB SMP:00606 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00606 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00606 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) ISO SMPDB SMP:00606 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Fmo1 flavin containing monooxygenase 1 ISO SMPDB SMP:00606 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179 		JBrowse link
G Fmo3 flavin containing monooxygenase 3 ISO SMPDB SMP:00606 NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097 		JBrowse link
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 ISO SMPDB SMP:00606 NCBI chr 7:126,272,042...126,289,615
Ensembl chr 7:126,272,037...126,275,604 		JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 ISO RGD PMID:16099924 PMID:19250197 RGD:5129555 RGD:5129558 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO RGD PMID:19250197 RGD:5129558 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 ISO SMPDB SMP:00606 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 ISO RGD PMID:19250197 RGD:5129558 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 ISO SMPDB SMP:00606 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 ISO RGD PMID:19250197 RGD:5129558 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 ISO RGD PMID:19250197 RGD:5129558 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796 		JBrowse link
teniposide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00443 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00443 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Mpo myeloperoxidase ISO SMPDB SMP:00443 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Top2a topoisomerase (DNA) II alpha ISO SMPDB SMP:00443 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
teniposide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00602 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00602 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Mpo myeloperoxidase ISO SMPDB SMP:00602 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Top2a topoisomerase (DNA) II alpha ISO SMPDB SMP:00602 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
tioguanine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP-binding cassette, sub-family C member 4 ISO SMPDB SMP:00430 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 ISO SMPDB SMP:00430 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144 		JBrowse link
G Ada adenosine deaminase ISO SMPDB SMP:00430 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159 		JBrowse link
G Adcy10 adenylate cyclase 10 ISO SMPDB SMP:00430 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
G Adk adenosine kinase ISO SMPDB SMP:00430 NCBI chr14:21,102,622...21,498,637
Ensembl chr14:21,102,642...21,498,637 		JBrowse link
G Adsl adenylosuccinate lyase ISO SMPDB SMP:00430 NCBI chr15:80,832,691...80,855,148
Ensembl chr15:80,832,691...80,855,147 		JBrowse link
G Adss2 adenylosuccinate synthase 2 ISO SMPDB SMP:00430 NCBI chr 1:177,590,742...177,624,064
Ensembl chr 1:177,590,528...177,624,077 		JBrowse link
G Ak1 adenylate kinase 1 ISO SMPDB SMP:00430 NCBI chr 2:32,511,770...32,525,070
Ensembl chr 2:32,511,770...32,525,070 		JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 ISO SMPDB SMP:00430 NCBI chr 3:102,981,330...103,007,038
Ensembl chr 3:102,981,330...103,007,036 		JBrowse link
G Aox1 aldehyde oxidase 1 ISO SMPDB SMP:00430 NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572 		JBrowse link
G Aprt adenine phosphoribosyl transferase ISO SMPDB SMP:00430 NCBI chr 8:123,301,376...123,303,646
Ensembl chr 8:123,301,374...123,303,648 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 ISO SMPDB SMP:00430 NCBI chr19:32,649,958...32,717,187
Ensembl chr19:32,649,038...32,717,186 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO SMPDB SMP:00430 NCBI chr 1:71,596,315...71,618,562
Ensembl chr 1:71,596,309...71,618,790 		JBrowse link
G Dguok deoxyguanosine kinase ISO SMPDB SMP:00430 NCBI chr 6:83,457,199...83,483,887
Ensembl chr 6:83,457,199...83,483,951 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 ISO SMPDB SMP:00430 NCBI chr12:84,420,649...84,455,803
Ensembl chr12:84,420,631...84,455,803 		JBrowse link
G Entpd8 ectonucleoside triphosphate diphosphohydrolase 8 ISO SMPDB SMP:00430 NCBI chr 2:24,969,308...24,975,731
Ensembl chr 2:24,970,316...24,975,728 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase ISO SMPDB SMP:00430 NCBI chr16:91,418,283...91,444,505
Ensembl chr16:91,418,074...91,443,840 		JBrowse link
G Gda guanine deaminase ISO SMPDB SMP:00430 NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809 		JBrowse link
G Gmpr guanosine monophosphate reductase ISO SMPDB SMP:00430 NCBI chr13:45,660,905...45,699,862
Ensembl chr13:45,660,920...45,707,276 		JBrowse link
G Gmps guanine monophosphate synthetase ISO SMPDB SMP:00430 NCBI chr 3:63,871,054...63,928,975
Ensembl chr 3:63,883,527...63,930,000 		JBrowse link
G Gucy1a2 guanylate cyclase 1, soluble, alpha 2 ISO SMPDB SMP:00430 NCBI chr 9:3,532,349...3,905,791
Ensembl chr 9:3,532,778...3,894,736 		JBrowse link
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 ISO SMPDB SMP:00430 NCBI chr 3:81,939,311...81,982,018
Ensembl chr 3:81,939,313...81,981,996 		JBrowse link
G Guk1 guanylate kinase 1 ISO SMPDB SMP:00430 NCBI chr11:59,074,696...59,083,068
Ensembl chr11:59,074,701...59,083,069 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO SMPDB SMP:00430 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 ISO SMPDB SMP:00430 NCBI chr 6:29,200,435...29,216,363
Ensembl chr 6:29,200,433...29,216,363 		JBrowse link
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) ISO SMPDB SMP:00430 NCBI chr 2:130,506,702...130,523,534
Ensembl chr 2:130,509,530...130,523,534 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 ISO SMPDB SMP:00430 NCBI chr 9:109,661,830...109,672,042
Ensembl chr 9:109,661,817...109,672,184 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II ISO SMPDB SMP:00430 NCBI chr19:46,873,829...47,003,613
Ensembl chr19:46,871,756...47,003,592 		JBrowse link
G Nudt2 nudix hydrolase 2 ISO SMPDB SMP:00430 NCBI chr 4:41,465,085...41,480,926
Ensembl chr 4:41,465,151...41,480,926 		JBrowse link
G Nudt5 nudix hydrolase 5 ISO SMPDB SMP:00430 NCBI chr 2:5,849,839...5,875,631
Ensembl chr 2:5,849,830...5,876,706 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase ISO SMPDB SMP:00430 NCBI chr 5:77,099,149...77,115,356
Ensembl chr 5:77,099,154...77,115,356 		JBrowse link
G Pde10a phosphodiesterase 10A ISO SMPDB SMP:00430 NCBI chr17:8,742,719...9,205,480
Ensembl chr17:8,744,204...9,205,480 		JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific ISO SMPDB SMP:00430 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995 		JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) ISO SMPDB SMP:00430 NCBI chr11:68,876,527...68,899,286
Ensembl chr11:68,876,523...68,899,286 		JBrowse link
G Pnp2 purine-nucleoside phosphorylase 2 ISO SMPDB SMP:00430 NCBI chr14:51,193,598...51,202,206
Ensembl chr14:51,193,449...51,202,206 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO SMPDB SMP:00430 NCBI chr 5:77,061,096...77,099,425
Ensembl chr 5:77,061,096...77,099,425 		JBrowse link
G Prps1l1 phosphoribosyl pyrophosphate synthetase 1-like 1 ISO SMPDB SMP:00430 NCBI chr12:35,034,760...35,036,435
Ensembl chr12:35,034,760...35,036,435 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO SMPDB SMP:00430 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rrm1 ribonucleotide reductase M1 ISO SMPDB SMP:00430 NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978 		JBrowse link
G Rrm2 ribonucleotide reductase M2 ISO SMPDB SMP:00430 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145 		JBrowse link
G Slc28a2 solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 ISO SMPDB SMP:00430 NCBI chr 2:122,256,836...122,291,633
Ensembl chr 2:122,256,958...122,291,618 		JBrowse link
G Slc28a3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 ISO SMPDB SMP:00430 NCBI chr13:58,701,121...58,758,691
Ensembl chr13:58,693,213...58,758,691 		JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 ISO SMPDB SMP:00430 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532 		JBrowse link
G Slc29a2 solute carrier family 29 (nucleoside transporters), member 2 ISO SMPDB SMP:00430 NCBI chr19:5,069,085...5,082,000
Ensembl chr19:5,073,888...5,082,000 		JBrowse link
G Tpmt thiopurine methyltransferase ISO SMPDB SMP:00430 NCBI chr13:47,175,463...47,196,833
Ensembl chr13:47,175,958...47,198,213 		JBrowse link
G Txn1 thioredoxin 1 ISO SMPDB SMP:00430 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411 		JBrowse link
G Xdh xanthine dehydrogenase ISO SMPDB SMP:00430 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
tioguanine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO SMPDB SMP:00647 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
trastuzumab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO SMPDB SMP:00476 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
vinblastine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00436 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 ISO SMPDB SMP:00436 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc10 ATP-binding cassette, sub-family C member 10 ISO SMPDB SMP:00436 NCBI chr17:46,614,146...46,638,954
Ensembl chr17:46,614,147...46,639,278 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO SMPDB SMP:00436 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 ISO SMPDB SMP:00436 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO SMPDB SMP:00436 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00436 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Ralbp1 ralA binding protein 1 ISO SMPDB SMP:00436 NCBI chr17:66,155,410...66,192,750
Ensembl chr17:66,155,413...66,192,793 		JBrowse link
G Trp53 transformation related protein 53 ISO SMPDB SMP:00436 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tuba1b tubulin, alpha 1B ISO SMPDB SMP:00436 NCBI chr15:98,829,310...98,832,271
Ensembl chr15:98,829,306...98,832,446 		JBrowse link
G Tubb1 tubulin, beta 1 class VI ISO SMPDB SMP:00436 NCBI chr 2:174,292,388...174,300,173
Ensembl chr 2:174,292,488...174,299,675 		JBrowse link
vincristine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00437 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 ISO SMPDB SMP:00437 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc10 ATP-binding cassette, sub-family C member 10 ISO SMPDB SMP:00437 NCBI chr17:46,614,146...46,638,954
Ensembl chr17:46,614,147...46,639,278 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO SMPDB SMP:00437 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 ISO SMPDB SMP:00437 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO SMPDB SMP:00437 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Ralbp1 ralA binding protein 1 ISO SMPDB SMP:00437 NCBI chr17:66,155,410...66,192,750
Ensembl chr17:66,155,413...66,192,793 		JBrowse link
G Trp53 transformation related protein 53 ISO SMPDB SMP:00437 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tuba1b tubulin, alpha 1B ISO SMPDB SMP:00437 NCBI chr15:98,829,310...98,832,271
Ensembl chr15:98,829,306...98,832,446 		JBrowse link
G Tubb1 tubulin, beta 1 class VI ISO SMPDB SMP:00437 NCBI chr 2:174,292,388...174,300,173
Ensembl chr 2:174,292,488...174,299,675 		JBrowse link
vindesine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00438 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 ISO SMPDB SMP:00438 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc10 ATP-binding cassette, sub-family C member 10 ISO SMPDB SMP:00438 NCBI chr17:46,614,146...46,638,954
Ensembl chr17:46,614,147...46,639,278 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO SMPDB SMP:00438 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 ISO SMPDB SMP:00438 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO SMPDB SMP:00438 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Ralbp1 ralA binding protein 1 ISO SMPDB SMP:00438 NCBI chr17:66,155,410...66,192,750
Ensembl chr17:66,155,413...66,192,793 		JBrowse link
G Trp53 transformation related protein 53 ISO SMPDB SMP:00438 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tuba1b tubulin, alpha 1B ISO SMPDB SMP:00438 NCBI chr15:98,829,310...98,832,271
Ensembl chr15:98,829,306...98,832,446 		JBrowse link
G Tubb1 tubulin, beta 1 class VI ISO SMPDB SMP:00438 NCBI chr 2:174,292,388...174,300,173
Ensembl chr 2:174,292,488...174,299,675 		JBrowse link
vinorelbine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00439 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 ISO SMPDB SMP:00439 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc10 ATP-binding cassette, sub-family C member 10 ISO SMPDB SMP:00439 NCBI chr17:46,614,146...46,638,954
Ensembl chr17:46,614,147...46,639,278 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO SMPDB SMP:00439 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 ISO SMPDB SMP:00439 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO SMPDB SMP:00439 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00439 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Ralbp1 ralA binding protein 1 ISO SMPDB SMP:00439 NCBI chr17:66,155,410...66,192,750
Ensembl chr17:66,155,413...66,192,793 		JBrowse link
G Trp53 transformation related protein 53 ISO SMPDB SMP:00439 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tuba1b tubulin, alpha 1B ISO SMPDB SMP:00439 NCBI chr15:98,829,310...98,832,271
Ensembl chr15:98,829,306...98,832,446 		JBrowse link
G Tubb1 tubulin, beta 1 class VI ISO SMPDB SMP:00439 NCBI chr 2:174,292,388...174,300,173
Ensembl chr 2:174,292,488...174,299,675 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6074
    drug pathway 402
      antineoplastic and immunomodulatory drug pathway 159
        antineoplastic drug pathway 158
          anti-estrogen drug pathway + 27
          axitinib drug pathway + 8
          bortezomib drug pathway + 0
          capecitabine drug pathway + 5
          cyclophosphamide drug pathway + 11
          docetaxel drug pathway + 7
          doxorubicin drug pathway + 20
          erlotinib drug pathway + 3
          etoposide drug pathway + 20
          everolimus drug pathway + 0
          gefitinib drug pathway + 6
          gemcitabine pathway + 13
          ifosfamide drug pathway + 10
          irinotecan drug pathway + 23
          mercaptopurine drug pathway + 47
          methotrexate drug pathway + 12
          monoclonal antibody drug pathway + 4
          pazopanib drug pathway + 0
          pemetrexed drug pathway + 0
          platinum (Pt) containing drug pathway + 9
          plevitrexed drug pathway + 0
          pralatrexate drug pathway + 0
          sorafenib drug pathway + 17
          sunitinib drug pathway + 0
          temsirolimus drug pathway + 0
          teniposide drug pathway + 4
          tioguanine drug pathway + 47
          vinca alkaloid drug pathway + 11
paths to the root