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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:antineoplastic drug pathway
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Accession:PW:0002367 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs used in the treatment of various cancers. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.


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aromatase inhibitor pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 TAS RGD PMID:18695261 RGD:5130880 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
axitinib pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT1 fms related receptor tyrosine kinase 1 TAS RGD PMID:22170007 RGD:6907361 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 TAS RGD PMID:22170007 RGD:6907361 NCBI chr 5:180,601,506...180,650,298
Ensembl chr 5:180,601,506...180,649,624 		JBrowse link
G KDR kinase insert domain receptor TAS RGD PMID:22170007 RGD:6907361 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
axitinib pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 TAS RGD PMID:22170007 RGD:6907361 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 TAS RGD PMID:22170007 RGD:6907361 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 TAS RGD PMID:22170007 RGD:6907361 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 TAS RGD PMID:22170007 RGD:6907361 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 TAS RGD PMID:22170007 RGD:6907361 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 TAS RGD PMID:22170007 RGD:6907361 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 TAS RGD PMID:22170007 RGD:6907361 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
bevacizumab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT1 fms related receptor tyrosine kinase 1 EXP SMPDB SMP:00420 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G KDR kinase insert domain receptor EXP SMPDB SMP:00420 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G VEGFA vascular endothelial growth factor A EXP SMPDB SMP:00420 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
capecitabine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDA cytidine deaminase EXP SMPDB SMP:00469 NCBI chr 1:20,589,097...20,618,903
Ensembl chr 1:20,589,086...20,618,903 		JBrowse link
G CES1 carboxylesterase 1 EXP SMPDB SMP:00469 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G SLC28A1 solute carrier family 28 member 1 EXP SMPDB SMP:00469 NCBI chr15:84,884,662...84,975,649
Ensembl chr15:84,884,654...84,945,798 		JBrowse link
G TYMP thymidine phosphorylase EXP SMPDB SMP:00469 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G TYMS thymidylate synthetase EXP SMPDB SMP:00469 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
capecitabine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDA cytidine deaminase EXP SMPDB SMP:00607 NCBI chr 1:20,589,097...20,618,903
Ensembl chr 1:20,589,086...20,618,903 		JBrowse link
G CES1 carboxylesterase 1 EXP SMPDB SMP:00607 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G SLC28A1 solute carrier family 28 member 1 EXP SMPDB SMP:00607 NCBI chr15:84,884,662...84,975,649
Ensembl chr15:84,884,654...84,945,798 		JBrowse link
G TYMP thymidine phosphorylase EXP SMPDB SMP:00607 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G TYMS thymidylate synthetase EXP SMPDB SMP:00607 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
cetuximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGFR epidermal growth factor receptor EXP SMPDB SMP:00474 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
cisplatin drug pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATOX1 antioxidant 1 copper chaperone TAS RGD PMID:23936210 RGD:8548474 NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532 		JBrowse link
G ATP7A ATPase copper transporting alpha TAS RGD PMID:22796517 RGD:8548473 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G ATP7B ATPase copper transporting beta TAS RGD PMID:22796517 RGD:8548473 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G HMGB1 high mobility group box 1 TAS RGD PMID:20046924 RGD:8548475 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G SLC31A1 solute carrier family 31 member 1 TAS
ISO 		RGD PMID:22796517 PMID:23123662 RGD:8548473, RGD:8549769 NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492 		JBrowse link
G SSRP1 structure specific recognition protein 1 TAS RGD PMID:20046924 RGD:8548475 NCBI chr11:57,325,988...57,335,892
Ensembl chr11:57,325,986...57,335,892 		JBrowse link
G TBP TATA-box binding protein TAS RGD PMID:20046924 RGD:8548475 NCBI chr 6:170,554,369...170,572,859
Ensembl chr 6:170,554,302...170,572,870 		JBrowse link
G UBTF upstream binding transcription factor TAS RGD PMID:20046924 RGD:8548475 NCBI chr17:44,205,040...44,221,304
Ensembl chr17:44,205,033...44,221,626 		JBrowse link
G YBX1 Y-box binding protein 1 TAS RGD PMID:20046924 RGD:8548475 NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805 		JBrowse link
cyclophosphamide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 EXP SMPDB SMP:00447 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 EXP SMPDB SMP:00447 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 EXP SMPDB SMP:00447 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00447 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 EXP SMPDB SMP:00447 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP SMPDB SMP:00447 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 EXP SMPDB SMP:00447 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00447 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 EXP SMPDB SMP:00447 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
cyclophosphamide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 EXP SMPDB SMP:00604 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 EXP SMPDB SMP:00604 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 EXP SMPDB SMP:00604 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00604 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 EXP SMPDB SMP:00604 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP SMPDB SMP:00604 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 EXP SMPDB SMP:00604 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00604 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 EXP SMPDB SMP:00604 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
docetaxel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00435 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP SMPDB SMP:00435 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP SMPDB SMP:00435 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) EXP SMPDB SMP:00435 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 EXP SMPDB SMP:00435 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G TUBA1B tubulin alpha 1b EXP SMPDB SMP:00435 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397 		JBrowse link
G TUBB1 tubulin beta 1 class VI EXP SMPDB SMP:00435 NCBI chr20:59,016,438...59,026,654
Ensembl chr20:59,019,429...59,026,654 		JBrowse link
doxorubicin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TOP2A DNA topoisomerase II alpha TAS RGD PMID:25895646 RGD:10395260 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TOP2B DNA topoisomerase II beta TAS RGD PMID:25895646 RGD:10395260 NCBI chr 3:25,597,905...25,664,907
Ensembl chr 3:25,597,978...25,664,909 		JBrowse link
doxorubicin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 TAS
EXP 		SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP SMPDB SMP:00650 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 TAS
EXP 		SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 TAS RGD PMID:21048526 RGD:10395261 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) TAS
EXP 		SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 TAS
EXP 		SMPDB
RGD		 PMID:21048526 PMID:19442138 SMP:00650, RGD:10395261, RGD:10395262 NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 TAS
EXP 		SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G CBR1 carbonyl reductase 1 TAS
EXP 		SMPDB
RGD		 PMID:21048526 PMID:19442138 SMP:00650, RGD:10395261, RGD:10395262 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166 		JBrowse link
G CBR3 carbonyl reductase 3 TAS
EXP 		SMPDB
RGD		 PMID:21048526 PMID:19442138 SMP:00650, RGD:10395261, RGD:10395262 NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562 		JBrowse link
G NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 EXP SMPDB SMP:00650 NCBI chr 1:161,197,417...161,214,395
Ensembl chr 1:161,197,104...161,214,723 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 EXP SMPDB SMP:00650 NCBI chr11:47,579,074...47,584,562
Ensembl chr11:47,565,336...47,584,562 		JBrowse link
G NDUFS7 NADH:ubiquinone oxidoreductase core subunit S7 EXP SMPDB SMP:00650 NCBI chr19:1,383,907...1,395,584
Ensembl chr19:1,383,527...1,395,589 		JBrowse link
G NOS3 nitric oxide synthase 3 TAS
EXP 		SMPDB
RGD		 PMID:19442138 SMP:00650, RGD:10395262 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 TAS
EXP 		SMPDB
RGD		 PMID:19442138 SMP:00650, RGD:10395262 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G POR cytochrome p450 oxidoreductase EXP SMPDB SMP:00650 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855 		JBrowse link
G RALBP1 ralA binding protein 1 TAS
EXP 		SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114 		JBrowse link
G SLC22A16 solute carrier family 22 member 16 TAS
EXP 		SMPDB
RGD		 PMID:21048526 SMP:00650, RGD:10395261 NCBI chr 6:110,424,687...110,476,613
Ensembl chr 6:110,424,687...110,476,641 		JBrowse link
G XDH xanthine dehydrogenase TAS
EXP 		SMPDB
RGD		 PMID:19442138 SMP:00650, RGD:10395262 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
erlotinib pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00472 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) EXP SMPDB SMP:00472 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G EGFR epidermal growth factor receptor EXP SMPDB SMP:00472 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
etoposide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00442 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 EXP SMPDB SMP:00442 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00442 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00442 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 EXP SMPDB SMP:00442 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 EXP SMPDB SMP:00442 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 EXP SMPDB SMP:00442 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP SMPDB SMP:00442 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HYOU1 hypoxia up-regulated 1 EXP SMPDB SMP:00442 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G MPO myeloperoxidase EXP SMPDB SMP:00442 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 EXP SMPDB SMP:00442 NCBI chr16:283,164...287,215
Ensembl chr16:283,164...287,215 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 EXP SMPDB SMP:00442 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 EXP SMPDB SMP:00442 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977 		JBrowse link
G PPIB peptidylprolyl isomerase B EXP SMPDB SMP:00442 NCBI chr15:64,155,817...64,163,022
Ensembl chr15:64,155,740...64,163,134 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP SMPDB SMP:00442 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP SMPDB SMP:00442 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 EXP SMPDB SMP:00442 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G TOP2A DNA topoisomerase II alpha EXP SMPDB SMP:00442 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TOP2B DNA topoisomerase II beta EXP SMPDB SMP:00442 NCBI chr 3:25,597,905...25,664,907
Ensembl chr 3:25,597,978...25,664,909 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 EXP SMPDB SMP:00442 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
etoposide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00601 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 EXP SMPDB SMP:00601 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00601 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00601 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 EXP SMPDB SMP:00601 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 EXP SMPDB SMP:00601 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 EXP SMPDB SMP:00601 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP SMPDB SMP:00601 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HYOU1 hypoxia up-regulated 1 EXP SMPDB SMP:00601 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G MPO myeloperoxidase EXP SMPDB SMP:00601 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 EXP SMPDB SMP:00601 NCBI chr16:283,164...287,215
Ensembl chr16:283,164...287,215 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 EXP SMPDB SMP:00601 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 EXP SMPDB SMP:00601 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977 		JBrowse link
G PPIB peptidylprolyl isomerase B EXP SMPDB SMP:00601 NCBI chr15:64,155,817...64,163,022
Ensembl chr15:64,155,740...64,163,134 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP SMPDB SMP:00601 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP SMPDB SMP:00601 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 EXP SMPDB SMP:00601 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G TOP2A DNA topoisomerase II alpha EXP SMPDB SMP:00601 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TOP2B DNA topoisomerase II beta EXP SMPDB SMP:00601 NCBI chr 3:25,597,905...25,664,907
Ensembl chr 3:25,597,978...25,664,909 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 EXP SMPDB SMP:00601 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
gefitinib pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGFR epidermal growth factor receptor TAS
EXP 		SMPDB
RGD		 PMID:19733976 SMP:00473, RGD:5135288 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
gefitinib pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 TAS RGD PMID:19733976 RGD:5135288 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) TAS RGD PMID:19733976 RGD:5135288 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 TAS RGD PMID:19733976 RGD:5135288 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) TAS RGD PMID:19733976 RGD:5135288 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 TAS RGD PMID:19733976 RGD:5135288 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 TAS RGD PMID:19733976 RGD:5135288 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
gemcitabine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK1 cytidine/uridine monophosphate kinase 1 EXP SMPDB SMP:00446 NCBI chr 1:47,333,790...47,378,839
Ensembl chr 1:47,333,790...47,394,866 		JBrowse link
G CTPS1 CTP synthase 1 EXP SMPDB SMP:00446 NCBI chr 1:40,979,696...41,012,565
Ensembl chr 1:40,979,300...41,012,565 		JBrowse link
G DCK deoxycytidine kinase EXP SMPDB SMP:00446 NCBI chr 4:70,993,649...71,030,914
Ensembl chr 4:70,992,538...71,030,914 		JBrowse link
G DCTD dCMP deaminase EXP SMPDB SMP:00446 NCBI chr 4:182,890,091...182,917,611
Ensembl chr 4:182,890,060...182,917,936 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 EXP SMPDB SMP:00446 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G NT5C 5', 3'-nucleotidase, cytosolic EXP SMPDB SMP:00446 NCBI chr17:75,130,228...75,131,742
Ensembl chr17:75,130,225...75,131,757 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 EXP SMPDB SMP:00446 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 EXP SMPDB SMP:00446 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B EXP SMPDB SMP:00446 NCBI chr 8:102,204,501...102,238,961
Ensembl chr 8:102,204,502...102,238,961 		JBrowse link
G SLC28A1 solute carrier family 28 member 1 EXP SMPDB SMP:00446 NCBI chr15:84,884,662...84,975,649
Ensembl chr15:84,884,654...84,945,798 		JBrowse link
G SLC28A3 solute carrier family 28 member 3 EXP SMPDB SMP:00446 NCBI chr 9:84,275,457...84,368,727
Ensembl chr 9:84,275,457...84,340,758 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) EXP SMPDB SMP:00446 NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142 		JBrowse link
G TYMS thymidylate synthetase EXP SMPDB SMP:00446 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
gemcitabine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK1 cytidine/uridine monophosphate kinase 1 EXP SMPDB SMP:00603 NCBI chr 1:47,333,790...47,378,839
Ensembl chr 1:47,333,790...47,394,866 		JBrowse link
G CTPS1 CTP synthase 1 EXP SMPDB SMP:00603 NCBI chr 1:40,979,696...41,012,565
Ensembl chr 1:40,979,300...41,012,565 		JBrowse link
G DCK deoxycytidine kinase EXP SMPDB SMP:00603 NCBI chr 4:70,993,649...71,030,914
Ensembl chr 4:70,992,538...71,030,914 		JBrowse link
G DCTD dCMP deaminase EXP SMPDB SMP:00603 NCBI chr 4:182,890,091...182,917,611
Ensembl chr 4:182,890,060...182,917,936 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 EXP SMPDB SMP:00603 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G NT5C 5', 3'-nucleotidase, cytosolic EXP SMPDB SMP:00603 NCBI chr17:75,130,228...75,131,742
Ensembl chr17:75,130,225...75,131,757 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 EXP SMPDB SMP:00603 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 EXP SMPDB SMP:00603 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B EXP SMPDB SMP:00603 NCBI chr 8:102,204,501...102,238,961
Ensembl chr 8:102,204,502...102,238,961 		JBrowse link
G SLC28A1 solute carrier family 28 member 1 EXP SMPDB SMP:00603 NCBI chr15:84,884,662...84,975,649
Ensembl chr15:84,884,654...84,945,798 		JBrowse link
G SLC28A3 solute carrier family 28 member 3 EXP SMPDB SMP:00603 NCBI chr 9:84,275,457...84,368,727
Ensembl chr 9:84,275,457...84,340,758 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) EXP SMPDB SMP:00603 NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142 		JBrowse link
G TYMS thymidylate synthetase EXP SMPDB SMP:00603 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
ifosfamide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 EXP SMPDB SMP:00448 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 EXP SMPDB SMP:00448 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 EXP SMPDB SMP:00448 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00448 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP SMPDB SMP:00448 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 EXP SMPDB SMP:00448 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00448 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00448 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
ifosfamide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 EXP SMPDB SMP:00605 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 EXP SMPDB SMP:00605 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 EXP SMPDB SMP:00605 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00605 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP SMPDB SMP:00605 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 EXP SMPDB SMP:00605 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00605 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00605 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
irinotecan pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00433 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP SMPDB SMP:00433 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP SMPDB SMP:00433 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) EXP SMPDB SMP:00433 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G BCHE butyrylcholinesterase EXP SMPDB SMP:00433 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G CES1 carboxylesterase 1 EXP SMPDB SMP:00433 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CES2 carboxylesterase 2 EXP SMPDB SMP:00433 NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00433 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00433 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 EXP SMPDB SMP:00433 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 EXP SMPDB SMP:00433 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 EXP SMPDB SMP:00433 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP SMPDB SMP:00433 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HYOU1 hypoxia up-regulated 1 EXP SMPDB SMP:00433 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 EXP SMPDB SMP:00433 NCBI chr16:283,164...287,215
Ensembl chr16:283,164...287,215 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 EXP SMPDB SMP:00433 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 EXP SMPDB SMP:00433 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977 		JBrowse link
G PPIB peptidylprolyl isomerase B EXP SMPDB SMP:00433 NCBI chr15:64,155,817...64,163,022
Ensembl chr15:64,155,740...64,163,134 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 EXP SMPDB SMP:00433 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 EXP SMPDB SMP:00433 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G TOP1 DNA topoisomerase I EXP SMPDB SMP:00433 NCBI chr20:41,028,822...41,124,487
Ensembl chr20:41,028,822...41,124,487 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 EXP SMPDB SMP:00433 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 EXP SMPDB SMP:00433 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 EXP SMPDB SMP:00433 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
irinotecan pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00600 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP SMPDB SMP:00600 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP SMPDB SMP:00600 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) EXP SMPDB SMP:00600 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G BCHE butyrylcholinesterase EXP SMPDB SMP:00600 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G CES1 carboxylesterase 1 EXP SMPDB SMP:00600 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CES2 carboxylesterase 2 EXP SMPDB SMP:00600 NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00600 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00600 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 EXP SMPDB SMP:00600 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 EXP SMPDB SMP:00600 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 EXP SMPDB SMP:00600 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP SMPDB SMP:00600 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HYOU1 hypoxia up-regulated 1 EXP SMPDB SMP:00600 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 EXP SMPDB SMP:00600 NCBI chr16:283,164...287,215
Ensembl chr16:283,164...287,215 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 EXP SMPDB SMP:00600 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 EXP SMPDB SMP:00600 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977 		JBrowse link
G PPIB peptidylprolyl isomerase B EXP SMPDB SMP:00600 NCBI chr15:64,155,817...64,163,022
Ensembl chr15:64,155,740...64,163,134 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 EXP SMPDB SMP:00600 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 EXP SMPDB SMP:00600 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G TOP1 DNA topoisomerase I EXP SMPDB SMP:00600 NCBI chr20:41,028,822...41,124,487
Ensembl chr20:41,028,822...41,124,487 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 EXP SMPDB SMP:00600 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 EXP SMPDB SMP:00600 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 EXP SMPDB SMP:00600 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
mercaptopurine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) EXP SMPDB SMP:00428 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 EXP SMPDB SMP:00428 NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939 		JBrowse link
G ADA adenosine deaminase EXP SMPDB SMP:00428 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADCY10 adenylate cyclase 10 EXP SMPDB SMP:00428 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G ADK adenosine kinase EXP SMPDB SMP:00428 NCBI chr10:74,151,221...74,709,290
Ensembl chr10:74,151,202...74,709,963 		JBrowse link
G ADSL adenylosuccinate lyase EXP SMPDB SMP:00428 NCBI chr22:40,346,500...40,387,527
Ensembl chr22:40,346,461...40,390,463 		JBrowse link
G ADSS2 adenylosuccinate synthase 2 EXP SMPDB SMP:00428 NCBI chr 1:244,408,494...244,452,060
Ensembl chr 1:244,408,494...244,451,909 		JBrowse link
G AK1 adenylate kinase 1 EXP SMPDB SMP:00428 NCBI chr 9:127,866,480...127,879,621
Ensembl chr 9:127,866,486...127,877,675 		JBrowse link
G AMPD1 adenosine monophosphate deaminase 1 EXP SMPDB SMP:00428 NCBI chr 1:114,673,098...114,695,546
Ensembl chr 1:114,673,090...114,695,618 		JBrowse link
G AOX1 aldehyde oxidase 1 EXP SMPDB SMP:00428 NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064 		JBrowse link
G APRT adenine phosphoribosyltransferase EXP SMPDB SMP:00428 NCBI chr16:88,809,339...88,811,928
Ensembl chr16:88,809,339...88,811,937 		JBrowse link
G ATAD1 ATPase family AAA domain containing 1 EXP SMPDB SMP:00428 NCBI chr10:87,751,512...87,841,361
Ensembl chr10:87,751,512...87,841,361 		JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase EXP SMPDB SMP:00428 NCBI chr 2:215,312,059...215,368,592
Ensembl chr 2:215,311,956...215,349,773 		JBrowse link
G DGUOK deoxyguanosine kinase EXP SMPDB SMP:00428 NCBI chr 2:73,926,880...73,958,946
Ensembl chr 2:73,926,826...73,958,961 		JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) EXP SMPDB SMP:00428 NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399 		JBrowse link
G ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 EXP SMPDB SMP:00428 NCBI chr 9:137,434,364...137,441,357
Ensembl chr 9:137,434,364...137,441,816 		JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase EXP SMPDB SMP:00428 NCBI chr21:33,503,931...33,542,893
Ensembl chr21:33,503,931...33,543,491 		JBrowse link
G GDA guanine deaminase EXP SMPDB SMP:00428 NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193 		JBrowse link
G GMPR guanosine monophosphate reductase EXP SMPDB SMP:00428 NCBI chr 6:16,238,587...16,295,549
Ensembl chr 6:16,238,587...16,295,549 		JBrowse link
G GMPS guanine monophosphate synthase EXP SMPDB SMP:00428 NCBI chr 3:155,869,430...155,944,020
Ensembl chr 3:155,870,650...155,944,020 		JBrowse link
G GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2 EXP SMPDB SMP:00428 NCBI chr11:106,674,019...107,018,476
Ensembl chr11:106,674,019...107,018,476 		JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 EXP SMPDB SMP:00428 NCBI chr 4:155,759,021...155,807,811
Ensembl chr 4:155,758,992...155,807,811 		JBrowse link
G GUK1 guanylate kinase 1 EXP SMPDB SMP:00428 NCBI chr 1:228,140,084...228,148,955
Ensembl chr 1:228,139,962...228,148,984 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 EXP SMPDB SMP:00428 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513 		JBrowse link
G IMPDH1 inosine monophosphate dehydrogenase 1 EXP SMPDB SMP:00428 NCBI chr 7:128,392,277...128,409,982
Ensembl chr 7:128,392,277...128,409,986 		JBrowse link
G ITPA inosine triphosphatase EXP SMPDB SMP:00428 NCBI chr20:3,204,065...3,227,449
Ensembl chr20:3,208,868...3,223,870 		JBrowse link
G NME6 NME/NM23 nucleoside diphosphate kinase 6 EXP SMPDB SMP:00428 NCBI chr 3:48,288,402...48,301,367
Ensembl chr 3:48,290,722...48,301,685 		JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II EXP SMPDB SMP:00428 NCBI chr10:103,088,017...103,193,272
Ensembl chr10:103,087,185...103,277,605 		JBrowse link
G NUDT2 nudix hydrolase 2 EXP SMPDB SMP:00428 NCBI chr 9:34,329,569...34,343,699
Ensembl chr 9:34,329,506...34,343,713 		JBrowse link
G NUDT5 nudix hydrolase 5 EXP SMPDB SMP:00428 NCBI chr10:12,165,330...12,195,891
Ensembl chr10:12,165,330...12,195,891 		JBrowse link
G PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase EXP SMPDB SMP:00428 NCBI chr 4:56,410,507...56,464,578
Ensembl chr 4:56,435,741...56,464,578 		JBrowse link
G PDE10A phosphodiesterase 10A EXP SMPDB SMP:00428 NCBI chr 6:165,327,289...165,988,052
Ensembl chr 6:165,327,287...165,988,117 		JBrowse link
G PDE4D phosphodiesterase 4D EXP SMPDB SMP:00428 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120 		JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase EXP SMPDB SMP:00428 NCBI chr17:8,247,608...8,270,486
Ensembl chr17:8,247,618...8,270,491 		JBrowse link
G PNP purine nucleoside phosphorylase EXP SMPDB SMP:00428 NCBI chr14:20,469,406...20,477,089
Ensembl chr14:20,461,992...20,477,094 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase EXP SMPDB SMP:00428 NCBI chr 4:56,393,362...56,435,615
Ensembl chr 4:56,393,362...56,435,615 		JBrowse link
G PRPS1L1 phosphoribosyl pyrophosphate synthetase 1 like 1 EXP SMPDB SMP:00428 NCBI chr 7:18,026,770...18,027,846
Ensembl chr 7:18,026,770...18,027,846 		JBrowse link
G RAC1 Rac family small GTPase 1 EXP SMPDB SMP:00428 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 EXP SMPDB SMP:00428 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 EXP SMPDB SMP:00428 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G SLC28A2 solute carrier family 28 member 2 EXP SMPDB SMP:00428 NCBI chr15:45,252,234...45,277,846
Ensembl chr15:45,252,234...45,277,846 		JBrowse link
G SLC28A3 solute carrier family 28 member 3 EXP SMPDB SMP:00428 NCBI chr 9:84,275,457...84,368,727
Ensembl chr 9:84,275,457...84,340,758 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) EXP SMPDB SMP:00428 NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142 		JBrowse link
G SLC29A2 solute carrier family 29 member 2 EXP SMPDB SMP:00428 NCBI chr11:66,362,521...66,372,446
Ensembl chr11:66,362,521...66,372,214 		JBrowse link
G TPMT thiopurine S-methyltransferase EXP SMPDB SMP:00428 NCBI chr 6:18,128,311...18,155,169
Ensembl chr 6:18,128,311...18,155,077 		JBrowse link
G TXN thioredoxin EXP SMPDB SMP:00428 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G XDH xanthine dehydrogenase EXP SMPDB SMP:00428 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
mercaptopurine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) EXP SMPDB SMP:00609 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 EXP SMPDB SMP:00609 NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939 		JBrowse link
G ADK adenosine kinase EXP SMPDB SMP:00609 NCBI chr10:74,151,221...74,709,290
Ensembl chr10:74,151,202...74,709,963 		JBrowse link
G AOX1 aldehyde oxidase 1 EXP SMPDB SMP:00609 NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064 		JBrowse link
G GMPS guanine monophosphate synthase EXP SMPDB SMP:00609 NCBI chr 3:155,869,430...155,944,020
Ensembl chr 3:155,870,650...155,944,020 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 EXP SMPDB SMP:00609 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513 		JBrowse link
G IMPDH1 inosine monophosphate dehydrogenase 1 EXP SMPDB SMP:00609 NCBI chr 7:128,392,277...128,409,982
Ensembl chr 7:128,392,277...128,409,986 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase EXP SMPDB SMP:00609 NCBI chr 4:56,393,362...56,435,615
Ensembl chr 4:56,393,362...56,435,615 		JBrowse link
G RAC1 Rac family small GTPase 1 EXP SMPDB SMP:00609 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G SLC28A2 solute carrier family 28 member 2 EXP SMPDB SMP:00609 NCBI chr15:45,252,234...45,277,846
Ensembl chr15:45,252,234...45,277,846 		JBrowse link
G SLC28A3 solute carrier family 28 member 3 EXP SMPDB SMP:00609 NCBI chr 9:84,275,457...84,368,727
Ensembl chr 9:84,275,457...84,340,758 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) EXP SMPDB SMP:00609 NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142 		JBrowse link
G SLC29A2 solute carrier family 29 member 2 EXP SMPDB SMP:00609 NCBI chr11:66,362,521...66,372,446
Ensembl chr11:66,362,521...66,372,214 		JBrowse link
G TPMT thiopurine S-methyltransferase EXP SMPDB SMP:00609 NCBI chr 6:18,128,311...18,155,169
Ensembl chr 6:18,128,311...18,155,077 		JBrowse link
G XDH xanthine dehydrogenase EXP SMPDB SMP:00609 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
methotrexate pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 EXP SMPDB SMP:00432 NCBI chr 3:126,103,570...126,197,945
Ensembl chr 3:126,103,562...126,197,994 		JBrowse link
G DHFR dihydrofolate reductase EXP SMPDB SMP:00432 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983 		JBrowse link
G FPGS folylpolyglutamate synthase EXP SMPDB SMP:00432 NCBI chr 9:127,802,858...127,814,506
Ensembl chr 9:127,794,597...127,814,494 		JBrowse link
G FTCD formimidoyltransferase cyclodeaminase EXP SMPDB SMP:00432 NCBI chr21:46,136,262...46,155,579
Ensembl chr21:46,136,160...46,155,579 		JBrowse link
G GGH gamma-glutamyl hydrolase EXP SMPDB SMP:00432 NCBI chr 8:63,015,079...63,038,806
Ensembl chr 8:63,014,881...63,039,407 		JBrowse link
G MTFMT mitochondrial methionyl-tRNA formyltransferase EXP SMPDB SMP:00432 NCBI chr15:65,001,512...65,029,639
Ensembl chr15:65,001,512...65,029,639 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 EXP SMPDB SMP:00432 NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457 		JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like EXP SMPDB SMP:00432 NCBI chr 6:150,865,702...151,101,887
Ensembl chr 6:150,865,679...151,101,887 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase EXP SMPDB SMP:00432 NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase EXP SMPDB SMP:00432 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MTHFS methenyltetrahydrofolate synthetase EXP SMPDB SMP:00432 NCBI chr15:79,843,547...79,897,285
Ensembl chr15:79,833,585...79,897,379 		JBrowse link
G SLC46A1 solute carrier family 46 member 1 EXP SMPDB SMP:00432 NCBI chr17:28,394,642...28,406,592
Ensembl chr17:28,394,642...28,407,197 		JBrowse link
panitumumab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGFR epidermal growth factor receptor EXP SMPDB SMP:00475 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
sorafenib pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00648 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP SMPDB SMP:00648 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 EXP SMPDB SMP:00648 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00648 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 EXP SMPDB SMP:00648 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 EXP SMPDB SMP:00648 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 EXP SMPDB SMP:00648 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP SMPDB SMP:00648 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HYOU1 hypoxia up-regulated 1 EXP SMPDB SMP:00648 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 EXP SMPDB SMP:00648 NCBI chr16:283,164...287,215
Ensembl chr16:283,164...287,215 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 EXP SMPDB SMP:00648 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 EXP SMPDB SMP:00648 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977 		JBrowse link
G PPIB peptidylprolyl isomerase B EXP SMPDB SMP:00648 NCBI chr15:64,155,817...64,163,022
Ensembl chr15:64,155,740...64,163,134 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 EXP SMPDB SMP:00648 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 EXP SMPDB SMP:00648 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 EXP SMPDB SMP:00648 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
tamoxifen pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00471 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) EXP SMPDB SMP:00471 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00471 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00471 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G ESR1 estrogen receptor 1 TAS
EXP 		SMPDB
RGD		 PMID:19629072 SMP:00471, RGD:5130191 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 TAS RGD PMID:19629072 RGD:5130191 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 EXP SMPDB SMP:00471 NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978 		JBrowse link
G FMO3 flavin containing dimethylaniline monoxygenase 3 EXP SMPDB SMP:00471 NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819 		JBrowse link
G NCOA3 nuclear receptor coactivator 3 TAS RGD PMID:16822624 RGD:5130718 NCBI chr20:47,501,887...47,656,872
Ensembl chr20:47,501,887...47,656,877 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 TAS RGD PMID:16822624 RGD:5130718 NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185 		JBrowse link
G NCOR2 nuclear receptor corepressor 2 TAS RGD PMID:16822624 RGD:5130718 NCBI chr12:124,324,415...124,567,612
Ensembl chr12:124,324,415...124,567,612 		JBrowse link
G PHB2 prohibitin 2 TAS RGD PMID:16822624 RGD:5130718 NCBI chr12:6,965,327...6,970,753
Ensembl chr12:6,965,327...6,970,780 		JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 EXP SMPDB SMP:00471 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044 		JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 EXP SMPDB SMP:00471 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300 		JBrowse link
G UGT1A4 UDP glucuronosyltransferase family 1 member A4 EXP SMPDB SMP:00471 NCBI chr 2:233,718,736...233,773,300
Ensembl chr 2:233,718,736...233,773,300 		JBrowse link
tamoxifen pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 IDA RGD PMID:21148080 RGD:5130188 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IDA RGD PMID:12971802 RGD:5129544 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 IDA RGD PMID:12971802 RGD:5129544 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 IDA
EXP 		SMPDB
RGD		 PMID:12971802 SMP:00606, RGD:5129544 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 IDA RGD PMID:12971802 RGD:5129544 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 IDA RGD PMID:12971802 RGD:5129544 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 IDA RGD PMID:12971802 RGD:5129544 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) IDA
EXP 		SMPDB
RGD		 PMID:12971802 SMP:00606, RGD:5129544 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 IDA
EXP 		SMPDB
RGD		 PMID:12971802 SMP:00606, RGD:5129544 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 IDA
EXP 		SMPDB
RGD		 PMID:12971802 SMP:00606, RGD:5129544 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G ESR1 estrogen receptor 1 EXP SMPDB SMP:00606 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 EXP SMPDB SMP:00606 NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978 		JBrowse link
G FMO3 flavin containing dimethylaniline monoxygenase 3 EXP SMPDB SMP:00606 NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819 		JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 TAS
EXP 		SMPDB
RGD		 PMID:19250197 SMP:00606, RGD:5129558 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 IDA
TAS 		RGD PMID:16099924 PMID:19250197 RGD:5129555, RGD:5129558 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 TAS RGD PMID:19250197 RGD:5129558 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 TAS
EXP 		SMPDB
RGD		 PMID:19250197 SMP:00606, RGD:5129558 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300 		JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 TAS RGD PMID:19250197 RGD:5129558 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300 		JBrowse link
G UGT1A4 UDP glucuronosyltransferase family 1 member A4 TAS
EXP 		SMPDB
RGD		 PMID:19250197 SMP:00606, RGD:5129558 NCBI chr 2:233,718,736...233,773,300
Ensembl chr 2:233,718,736...233,773,300 		JBrowse link
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 TAS RGD PMID:19250197 RGD:5129558 NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300 		JBrowse link
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 TAS RGD PMID:19250197 RGD:5129558 NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 TAS RGD PMID:19250197 RGD:5129558 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 TAS RGD PMID:19250197 RGD:5129558 NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987 		JBrowse link
teniposide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00443 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00443 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G MPO myeloperoxidase EXP SMPDB SMP:00443 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G TOP2A DNA topoisomerase II alpha EXP SMPDB SMP:00443 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
teniposide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00602 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00602 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G MPO myeloperoxidase EXP SMPDB SMP:00602 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G TOP2A DNA topoisomerase II alpha EXP SMPDB SMP:00602 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
tioguanine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) EXP SMPDB SMP:00430 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 EXP SMPDB SMP:00430 NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939 		JBrowse link
G ADA adenosine deaminase EXP SMPDB SMP:00430 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADCY10 adenylate cyclase 10 EXP SMPDB SMP:00430 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G ADK adenosine kinase EXP SMPDB SMP:00430 NCBI chr10:74,151,221...74,709,290
Ensembl chr10:74,151,202...74,709,963 		JBrowse link
G ADSL adenylosuccinate lyase EXP SMPDB SMP:00430 NCBI chr22:40,346,500...40,387,527
Ensembl chr22:40,346,461...40,390,463 		JBrowse link
G ADSS2 adenylosuccinate synthase 2 EXP SMPDB SMP:00430 NCBI chr 1:244,408,494...244,452,060
Ensembl chr 1:244,408,494...244,451,909 		JBrowse link
G AK1 adenylate kinase 1 EXP SMPDB SMP:00430 NCBI chr 9:127,866,480...127,879,621
Ensembl chr 9:127,866,486...127,877,675 		JBrowse link
G AMPD1 adenosine monophosphate deaminase 1 EXP SMPDB SMP:00430 NCBI chr 1:114,673,098...114,695,546
Ensembl chr 1:114,673,090...114,695,618 		JBrowse link
G AOX1 aldehyde oxidase 1 EXP SMPDB SMP:00430 NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064 		JBrowse link
G APRT adenine phosphoribosyltransferase EXP SMPDB SMP:00430 NCBI chr16:88,809,339...88,811,928
Ensembl chr16:88,809,339...88,811,937 		JBrowse link
G ATAD1 ATPase family AAA domain containing 1 EXP SMPDB SMP:00430 NCBI chr10:87,751,512...87,841,361
Ensembl chr10:87,751,512...87,841,361 		JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase EXP SMPDB SMP:00430 NCBI chr 2:215,312,059...215,368,592
Ensembl chr 2:215,311,956...215,349,773 		JBrowse link
G DGUOK deoxyguanosine kinase EXP SMPDB SMP:00430 NCBI chr 2:73,926,880...73,958,946
Ensembl chr 2:73,926,826...73,958,961 		JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) EXP SMPDB SMP:00430 NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399 		JBrowse link
G ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 EXP SMPDB SMP:00430 NCBI chr 9:137,434,364...137,441,357
Ensembl chr 9:137,434,364...137,441,816 		JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase EXP SMPDB SMP:00430 NCBI chr21:33,503,931...33,542,893
Ensembl chr21:33,503,931...33,543,491 		JBrowse link
G GDA guanine deaminase EXP SMPDB SMP:00430 NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193 		JBrowse link
G GMPR guanosine monophosphate reductase EXP SMPDB SMP:00430 NCBI chr 6:16,238,587...16,295,549
Ensembl chr 6:16,238,587...16,295,549 		JBrowse link
G GMPS guanine monophosphate synthase EXP SMPDB SMP:00430 NCBI chr 3:155,869,430...155,944,020
Ensembl chr 3:155,870,650...155,944,020 		JBrowse link
G GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2 EXP SMPDB SMP:00430 NCBI chr11:106,674,019...107,018,476
Ensembl chr11:106,674,019...107,018,476 		JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 EXP SMPDB SMP:00430 NCBI chr 4:155,759,021...155,807,811
Ensembl chr 4:155,758,992...155,807,811 		JBrowse link
G GUK1 guanylate kinase 1 EXP SMPDB SMP:00430 NCBI chr 1:228,140,084...228,148,955
Ensembl chr 1:228,139,962...228,148,984 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 EXP SMPDB SMP:00430 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513 		JBrowse link
G IMPDH1 inosine monophosphate dehydrogenase 1 EXP SMPDB SMP:00430 NCBI chr 7:128,392,277...128,409,982
Ensembl chr 7:128,392,277...128,409,986 		JBrowse link
G ITPA inosine triphosphatase EXP SMPDB SMP:00430 NCBI chr20:3,204,065...3,227,449
Ensembl chr20:3,208,868...3,223,870 		JBrowse link
G NME6 NME/NM23 nucleoside diphosphate kinase 6 EXP SMPDB SMP:00430 NCBI chr 3:48,288,402...48,301,367
Ensembl chr 3:48,290,722...48,301,685 		JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II EXP SMPDB SMP:00430 NCBI chr10:103,088,017...103,193,272
Ensembl chr10:103,087,185...103,277,605 		JBrowse link
G NUDT2 nudix hydrolase 2 EXP SMPDB SMP:00430 NCBI chr 9:34,329,569...34,343,699
Ensembl chr 9:34,329,506...34,343,713 		JBrowse link
G NUDT5 nudix hydrolase 5 EXP SMPDB SMP:00430 NCBI chr10:12,165,330...12,195,891
Ensembl chr10:12,165,330...12,195,891 		JBrowse link
G PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase EXP SMPDB SMP:00430 NCBI chr 4:56,410,507...56,464,578
Ensembl chr 4:56,435,741...56,464,578 		JBrowse link
G PDE10A phosphodiesterase 10A EXP SMPDB SMP:00430 NCBI chr 6:165,327,289...165,988,052
Ensembl chr 6:165,327,287...165,988,117 		JBrowse link
G PDE4D phosphodiesterase 4D EXP SMPDB SMP:00430 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120 		JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase EXP SMPDB SMP:00430 NCBI chr17:8,247,608...8,270,486
Ensembl chr17:8,247,618...8,270,491 		JBrowse link
G PNP purine nucleoside phosphorylase EXP SMPDB SMP:00430 NCBI chr14:20,469,406...20,477,089
Ensembl chr14:20,461,992...20,477,094 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase EXP SMPDB SMP:00430 NCBI chr 4:56,393,362...56,435,615
Ensembl chr 4:56,393,362...56,435,615 		JBrowse link
G PRPS1L1 phosphoribosyl pyrophosphate synthetase 1 like 1 EXP SMPDB SMP:00430 NCBI chr 7:18,026,770...18,027,846
Ensembl chr 7:18,026,770...18,027,846 		JBrowse link
G RAC1 Rac family small GTPase 1 EXP SMPDB SMP:00430 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 EXP SMPDB SMP:00430 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 EXP SMPDB SMP:00430 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G SLC28A2 solute carrier family 28 member 2 EXP SMPDB SMP:00430 NCBI chr15:45,252,234...45,277,846
Ensembl chr15:45,252,234...45,277,846 		JBrowse link
G SLC28A3 solute carrier family 28 member 3 EXP SMPDB SMP:00430 NCBI chr 9:84,275,457...84,368,727
Ensembl chr 9:84,275,457...84,340,758 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) EXP SMPDB SMP:00430 NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142 		JBrowse link
G SLC29A2 solute carrier family 29 member 2 EXP SMPDB SMP:00430 NCBI chr11:66,362,521...66,372,446
Ensembl chr11:66,362,521...66,372,214 		JBrowse link
G TPMT thiopurine S-methyltransferase EXP SMPDB SMP:00430 NCBI chr 6:18,128,311...18,155,169
Ensembl chr 6:18,128,311...18,155,077 		JBrowse link
G TXN thioredoxin EXP SMPDB SMP:00430 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G XDH xanthine dehydrogenase EXP SMPDB SMP:00430 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
tioguanine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPRT1 hypoxanthine phosphoribosyltransferase 1 EXP SMPDB SMP:00647 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513 		JBrowse link
trastuzumab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGFR epidermal growth factor receptor EXP SMPDB SMP:00476 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
vinblastine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00436 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP SMPDB SMP:00436 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC10 ATP binding cassette subfamily C member 10 EXP SMPDB SMP:00436 NCBI chr 6:43,427,541...43,451,994
Ensembl chr 6:43,427,366...43,450,430 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP SMPDB SMP:00436 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 EXP SMPDB SMP:00436 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A EXP SMPDB SMP:00436 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00436 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G RALBP1 ralA binding protein 1 EXP SMPDB SMP:00436 NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114 		JBrowse link
G TP53 tumor protein p53 EXP SMPDB SMP:00436 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TUBA1B tubulin alpha 1b EXP SMPDB SMP:00436 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397 		JBrowse link
G TUBB1 tubulin beta 1 class VI EXP SMPDB SMP:00436 NCBI chr20:59,016,438...59,026,654
Ensembl chr20:59,019,429...59,026,654 		JBrowse link
vincristine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00437 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP SMPDB SMP:00437 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC10 ATP binding cassette subfamily C member 10 EXP SMPDB SMP:00437 NCBI chr 6:43,427,541...43,451,994
Ensembl chr 6:43,427,366...43,450,430 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP SMPDB SMP:00437 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 EXP SMPDB SMP:00437 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A EXP SMPDB SMP:00437 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G RALBP1 ralA binding protein 1 EXP SMPDB SMP:00437 NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114 		JBrowse link
G TP53 tumor protein p53 EXP SMPDB SMP:00437 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TUBA1B tubulin alpha 1b EXP SMPDB SMP:00437 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397 		JBrowse link
G TUBB1 tubulin beta 1 class VI EXP SMPDB SMP:00437 NCBI chr20:59,016,438...59,026,654
Ensembl chr20:59,019,429...59,026,654 		JBrowse link
vindesine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00438 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP SMPDB SMP:00438 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC10 ATP binding cassette subfamily C member 10 EXP SMPDB SMP:00438 NCBI chr 6:43,427,541...43,451,994
Ensembl chr 6:43,427,366...43,450,430 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP SMPDB SMP:00438 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 EXP SMPDB SMP:00438 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A EXP SMPDB SMP:00438 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G RALBP1 ralA binding protein 1 EXP SMPDB SMP:00438 NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114 		JBrowse link
G TP53 tumor protein p53 EXP SMPDB SMP:00438 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TUBA1B tubulin alpha 1b EXP SMPDB SMP:00438 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397 		JBrowse link
G TUBB1 tubulin beta 1 class VI EXP SMPDB SMP:00438 NCBI chr20:59,016,438...59,026,654
Ensembl chr20:59,019,429...59,026,654 		JBrowse link
vinorelbine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00439 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP SMPDB SMP:00439 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC10 ATP binding cassette subfamily C member 10 EXP SMPDB SMP:00439 NCBI chr 6:43,427,541...43,451,994
Ensembl chr 6:43,427,366...43,450,430 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP SMPDB SMP:00439 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 EXP SMPDB SMP:00439 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A EXP SMPDB SMP:00439 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00439 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G RALBP1 ralA binding protein 1 EXP SMPDB SMP:00439 NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114 		JBrowse link
G TP53 tumor protein p53 EXP SMPDB SMP:00439 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TUBA1B tubulin alpha 1b EXP SMPDB SMP:00439 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397 		JBrowse link
G TUBB1 tubulin beta 1 class VI EXP SMPDB SMP:00439 NCBI chr20:59,016,438...59,026,654
Ensembl chr20:59,019,429...59,026,654 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    drug pathway 412
      antineoplastic and immunomodulatory drug pathway 160
        antineoplastic drug pathway 159
          anti-estrogen drug pathway + 29
          axitinib drug pathway + 10
          bortezomib drug pathway + 0
          capecitabine drug pathway + 5
          cyclophosphamide drug pathway + 9
          docetaxel drug pathway + 7
          doxorubicin drug pathway + 20
          erlotinib drug pathway + 3
          etoposide drug pathway + 20
          everolimus drug pathway + 0
          gefitinib drug pathway + 7
          gemcitabine pathway + 13
          ifosfamide drug pathway + 8
          irinotecan drug pathway + 24
          mercaptopurine drug pathway + 47
          methotrexate drug pathway + 12
          monoclonal antibody drug pathway + 4
          pazopanib drug pathway + 0
          pemetrexed drug pathway + 0
          platinum (Pt) containing drug pathway + 9
          plevitrexed drug pathway + 0
          pralatrexate drug pathway + 0
          sorafenib drug pathway + 16
          sunitinib drug pathway + 0
          temsirolimus drug pathway + 0
          teniposide drug pathway + 4
          tioguanine drug pathway + 47
          vinca alkaloid drug pathway + 11
paths to the root