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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:lornoxicam pharmacodynamics pathway
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Accession:PW:0002350 term browser browse the term
Definition:The pathway of lornoxicam-target interaction and of the biochemical or physiological responses to drug. The drug is used to relieve various types of pain. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00700

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lornoxicam pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 ISO SMPDB SMP:00700 NCBI chr 9:5,237,176...5,254,772 JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00700 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00700 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00700 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00700 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00700 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00700 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00700 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00700 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00700 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00700 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00700 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00700 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00700 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00700 NCBI chr19:7,389,009...7,411,229 JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00700 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00700 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00700 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00700 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00700 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00700 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00700 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00700 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00700 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00700 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00700 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00700 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4056
    drug pathway 388
      musculo-skeletal system drug pathway 66
        lornoxicam drug pathway 27
          lornoxicam pharmacodynamics pathway 27
Path 2
Term Annotations click to browse term
  pathway 4056
    drug pathway 388
      nervous system drug pathway 175
        analgesic and/or antipyretic drug pathway 91
          lornoxicam drug pathway 27
            lornoxicam pharmacodynamics pathway 27
paths to the root