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Pathways

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).

Term:citalopram pharmacokinetics pathway
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Accession:PW:0002117 term browser browse the term
Definition:The pathway of processing - absorption, distribution, metabolism or elimination - of citalopram. Genetic variations can result in changes in the availability of the drug.
Synonyms:related_synonym: SMP:00627



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citalopram pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aox1 aldehyde oxidase 1 ISO SMPDB SMP:00627 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 ISO SMPDB SMP:00627 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO SMPDB SMP:00627 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Maoa monoamine oxidase A ISO SMPDB SMP:00627 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631
JBrowse link
G Maob monoamine oxidase B ISO SMPDB SMP:00627 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375
JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO SMPDB SMP:00627 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056
JBrowse link

Term paths to the root
Path 1
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  pathway 6091
    drug pathway 397
      nervous system drug pathway 183
        antidepressant drug pathway 39
          selective serotonin uptake inhibitor drug pathway 37
            citalopram drug pathway 35
              citalopram pharmacokinetics pathway 6
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