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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:risedronate pharmacodynamics pathway
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Accession:PW:0001838 term browser browse the term
Definition:The pathway of risedronate-target interaction and of the biochemical or physiological responses to drug. Risedronate is a nitrogenous bisphosphonate drug used to treat bone diseases. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00112


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risedronate pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 ISO SMPDB SMP:00112 NCBI chr 1:7,600,616...7,612,861
Ensembl chr 1:7,598,735...7,612,866 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO SMPDB SMP:00112 NCBI chr 9:72,057,506...72,079,587
Ensembl chr 9:72,057,511...72,079,444 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase ISO SMPDB SMP:00112 NCBI chr 6:157,483,794...157,519,060
Ensembl chr 6:157,483,783...157,519,061 		JBrowse link
G EBP EBP cholestenol delta-isomerase ISO SMPDB SMP:00112 NCBI chr  X:42,670,592...42,678,571
Ensembl chr  X:42,670,633...42,678,570 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 ISO SMPDB SMP:00112 NCBI chr14:14,976,259...15,010,701
Ensembl chr14:14,967,074...15,016,227 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO SMPDB SMP:00112 NCBI chr 4:94,500,140...94,514,820
Ensembl chr 4:94,500,141...94,518,408 		JBrowse link
G GGPS1 geranylgeranyl diphosphate synthase 1 ISO SMPDB SMP:00112 NCBI chr14:55,907,885...55,924,037
Ensembl chr14:55,908,674...55,923,988 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO SMPDB SMP:00112 NCBI chr 2:84,380,245...84,401,117
Ensembl chr 2:84,380,224...84,402,957 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO SMPDB SMP:00112 NCBI chr16:27,936,225...27,957,261
Ensembl chr16:27,936,218...27,957,193 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 ISO SMPDB SMP:00112 NCBI chr 4:87,720,747...87,743,037
Ensembl chr 4:87,720,118...87,742,992 		JBrowse link
G LIPA lipase A, lysosomal acid type ISO SMPDB SMP:00112 NCBI chr14:101,131,372...101,254,739
Ensembl chr14:101,126,257...101,193,614 		JBrowse link
G LOC100625049 isopentenyl-diphosphate Delta-isomerase 1 ISO SMPDB SMP:00112 NCBI chr10:68,534,520...68,539,279
Ensembl chr10:68,534,796...68,539,280 		JBrowse link
G LSS lanosterol synthase ISO SMPDB SMP:00112
G MSMO1 methylsterol monooxygenase 1 ISO SMPDB SMP:00112 NCBI chr 8:43,726,834...43,745,784
Ensembl chr 8:43,726,858...43,744,713 		JBrowse link
G MVD mevalonate diphosphate decarboxylase ISO SMPDB SMP:00112 NCBI chr 6:1,008,100...1,014,303
Ensembl chr 6:1,008,100...1,014,303 		JBrowse link
G MVK mevalonate kinase ISO SMPDB SMP:00112 NCBI chr14:41,320,790...41,357,437
Ensembl chr14:41,281,673...41,357,368 		JBrowse link
G NSDHL NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL ISO SMPDB SMP:00112 NCBI chr  X:123,906,130...123,921,935
Ensembl chr  X:123,906,199...123,929,117 		JBrowse link
G PMVK phosphomevalonate kinase ISO SMPDB SMP:00112 NCBI chr 4:94,861,500...94,913,743
Ensembl chr 4:94,861,712...94,874,771 		JBrowse link
G SC5D sterol-C5-desaturase ISO SMPDB SMP:00112 NCBI chr 9:48,357,115...48,372,391
Ensembl chr 9:48,357,165...48,372,386 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 ISO SMPDB SMP:00112 NCBI chr 9:121,045,211...121,112,393
Ensembl chr 9:121,045,234...121,113,692 		JBrowse link
G SQLE squalene epoxidase ISO SMPDB SMP:00112 NCBI chr 4:14,669,789...14,700,152
Ensembl chr 4:14,669,791...14,700,126 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 ISO SMPDB SMP:00112 NCBI chr 2:7,076,778...7,081,502
Ensembl chr 2:7,075,068...7,081,432 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4043
    drug pathway 384
      musculo-skeletal system drug pathway 64
        bisphosphonate drug pathway 22
          nitrogenous bisphosphonate drug pathway 22
            risedronate drug pathway 22
              risedronate pharmacodynamics pathway 22
paths to the root