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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:mRNA nuclear export pathway
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Accession:PW:0001587 term browser browse the term
Definition:The pathway thereby processed, mature mRNA is exported to the cytoplasm. Two distinct export pathways are mediated by specific transport receptors. The NXF1-NXT1 heterodimer exports the bulk of mRNA whereas a subset of mRNA is exported by the CRM1 system.
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mRNA nuclear export pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nup107 nucleoporin 107 ISO RGD PMID:25184662 RGD:9743947 NCBI chr10:117,586,526...117,628,607
Ensembl chr10:117,586,526...117,628,610 		JBrowse link
G Nup133 nucleoporin 133 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 8:124,623,862...124,676,019
Ensembl chr 8:124,623,862...124,676,004 		JBrowse link
G Nup153 nucleoporin 153 ISO RGD PMID:25184662 RGD:9743947 NCBI chr13:46,833,369...46,890,682
Ensembl chr13:46,833,381...46,881,416 		JBrowse link
G Nup160 nucleoporin 160 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 2:90,504,405...90,570,217
Ensembl chr 2:90,507,559...90,566,672 		JBrowse link
G Nup214 nucleoporin 214 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 2:31,864,446...31,943,204
Ensembl chr 2:31,864,448...31,943,987 		JBrowse link
G Nup37 nucleoporin 37 ISO RGD PMID:25184662 RGD:9743947 NCBI chr10:87,982,838...88,014,257
Ensembl chr10:87,982,854...88,014,252 		JBrowse link
G Nup43 nucleoporin 43 ISO RGD PMID:25184662 RGD:9743947 NCBI chr10:7,543,268...7,554,650
Ensembl chr10:7,543,267...7,554,645 		JBrowse link
G Nup54 nucleoporin 54 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 5:92,563,399...92,583,117
Ensembl chr 5:92,563,399...92,583,078 		JBrowse link
G Nup58 nucleoporin 58 ISO RGD PMID:25184662 RGD:9743947 NCBI chr14:60,442,733...60,488,951
Ensembl chr14:60,422,061...60,488,880
Ensembl chr14:60,422,061...60,488,880 		JBrowse link
G Nup62 nucleoporin 62 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 7:44,465,512...44,481,260
Ensembl chr 7:44,465,512...44,480,236 		JBrowse link
G Nup85 nucleoporin 85 ISO RGD PMID:25184662 RGD:9743947 NCBI chr11:115,455,264...115,474,750
Ensembl chr11:115,455,260...115,474,811 		JBrowse link
G Nup98 nucleoporin 98 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 7:101,768,607...101,859,359
Ensembl chr 7:101,768,605...101,859,383 		JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component ISO RGD PMID:25184662 RGD:9743947 NCBI chr 6:113,705,013...113,717,642
Ensembl chr 6:113,705,023...113,717,704 		JBrowse link
G Seh1l SEH1-like (S. cerevisiae ISO RGD PMID:25184662 RGD:9743947 NCBI chr18:67,907,946...67,928,557
Ensembl chr18:67,907,946...67,928,557 		JBrowse link
CRM1 export pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anp32a acidic nuclear phosphoprotein 32 family member A ISO RGD PMID:23583578 RGD:9743967 NCBI chr 9:62,248,637...62,286,084
Ensembl chr 9:62,248,575...62,286,094 		JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B ISO RGD PMID:23583578 RGD:9743967 NCBI chr 4:46,450,926...46,472,657
Ensembl chr 4:46,450,902...46,472,657 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E ISO RGD PMID:23583578 RGD:9743967 NCBI chr 3:138,231,952...138,265,457
Ensembl chr 3:138,231,940...138,265,457 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413 		JBrowse link
G Lrpprc leucine-rich PPR-motif containing ISO RGD PMID:23583578 RGD:9743967 NCBI chr17:85,012,675...85,098,214
Ensembl chr17:85,012,675...85,098,217 		JBrowse link
G Nup98 nucleoporin 98 ISO RGD PMID:23583578 RGD:9743967 NCBI chr 7:101,768,607...101,859,359
Ensembl chr 7:101,768,605...101,859,383 		JBrowse link
G Nxf3 nuclear RNA export factor 3 ISO RGD PMID:23583578 RGD:9743967 NCBI chr  X:134,972,272...135,040,382
Ensembl chr  X:134,972,848...134,986,004 		JBrowse link
G Ran RAN, member RAS oncogene family ISO RGD PMID:23583578 RGD:9743967 NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387 		JBrowse link
G Ranbp1 RAN binding protein 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr16:18,057,843...18,066,558
Ensembl chr16:18,057,648...18,066,596 		JBrowse link
G Ranbp2 RAN binding protein 2 ISO RGD PMID:23583578 RGD:9743967 NCBI chr10:58,282,674...58,329,977
Ensembl chr10:58,282,742...58,330,178 		JBrowse link
G Rangap1 RAN GTPase activating protein 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr15:81,588,449...81,614,120
Ensembl chr15:81,588,449...81,629,731 		JBrowse link
G Xpo1 exportin 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr11:23,205,768...23,248,250
Ensembl chr11:23,206,055...23,248,249 		JBrowse link
NXF1-NXT1 export pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alyref Aly/REF export factor ISO RGD PMID:22178508 RGD:9743960 NCBI chr11:120,485,330...120,489,342
Ensembl chr11:120,482,947...120,489,191 		JBrowse link
G Ddx19b DEAD box helicase 19b ISO RGD PMID:23583578 RGD:9743967 NCBI chr 8:111,729,818...111,758,383
Ensembl chr 8:111,729,820...111,758,383 		JBrowse link
G Ddx39b DEAD box helicase 39b ISO RGD PMID:22178508 RGD:9743960 NCBI chr17:35,460,722...35,472,683
Ensembl chr17:35,460,722...35,472,683 		JBrowse link
G Gle1 GLE1 RNA export mediator ISO RGD PMID:23583578 RGD:9743967 NCBI chr 2:29,825,421...29,849,444
Ensembl chr 2:29,825,438...29,850,383 		JBrowse link
G Nup214 nucleoporin 214 ISO RGD PMID:23583578 RGD:9743967 NCBI chr 2:31,864,446...31,943,204
Ensembl chr 2:31,864,448...31,943,987 		JBrowse link
G Nxf1 nuclear RNA export factor 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr19:8,734,467...8,748,274
Ensembl chr19:8,734,437...8,748,286 		JBrowse link
G Nxt1 NTF2-related export protein 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr 2:148,514,535...148,517,946
Ensembl chr 2:148,514,521...148,517,947 		JBrowse link
G Sarnp SAP domain containing ribonucleoprotein ISO RGD PMID:22178508 RGD:9743960 NCBI chr10:128,657,633...128,713,507
Ensembl chr10:128,653,202...128,713,498 		JBrowse link
G Thoc1 THO complex 1 ISO RGD PMID:22178508 RGD:9743960 NCBI chr18:9,958,176...9,995,486
Ensembl chr18:9,957,906...9,995,489 		JBrowse link
G Thoc2 THO complex 2 ISO RGD PMID:22178508 RGD:9743960 NCBI chr  X:40,883,869...41,000,878
Ensembl chr  X:40,883,868...41,009,551 		JBrowse link
G Thoc5 THO complex 5 ISO RGD PMID:22178508 RGD:9743960 NCBI chr11:4,845,339...4,878,867
Ensembl chr11:4,845,320...4,878,867 		JBrowse link
G Thoc6 THO complex 6 ISO RGD PMID:22178508 RGD:9743960 NCBI chr17:23,887,592...23,892,891
Ensembl chr17:23,887,588...23,892,856 		JBrowse link
G Thoc7 THO complex 7 ISO RGD PMID:22178508 RGD:9743960 NCBI chr14:8,507,911...8,520,751
Ensembl chr14:8,507,911...8,520,751 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6074
    regulatory pathway 3686
      transport pathway 357
        RNA transport pathway 37
          mRNA nuclear export pathway 37
            CRM1 export pathway 12
            NXF1-NXT1 export pathway 13
paths to the root