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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:mRNA nuclear export pathway
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Accession:PW:0001587 term browser browse the term
Definition:The pathway thereby processed, mature mRNA is exported to the cytoplasm. Two distinct export pathways are mediated by specific transport receptors. The NXF1-NXT1 heterodimer exports the bulk of mRNA whereas a subset of mRNA is exported by the CRM1 system.
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mRNA nuclear export pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nup107 nucleoporin 107 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 7:53,353,740...53,398,345
Ensembl chr 7:53,353,743...53,398,370 		JBrowse link
G Nup133 nucleoporin 133 ISO RGD PMID:25184662 RGD:9743947 NCBI chr19:51,891,606...51,941,243
Ensembl chr19:51,891,629...51,941,239 		JBrowse link
G Nup153 nucleoporin 153 ISO RGD PMID:25184662 RGD:9743947 NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876 		JBrowse link
G Nup160 nucleoporin 160 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 3:76,665,786...76,729,296
Ensembl chr 3:76,665,786...76,724,565 		JBrowse link
G Nup214 nucleoporin 214 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 3:15,255,111...15,340,568
Ensembl chr 3:15,255,119...15,340,568 		JBrowse link
G Nup37 nucleoporin 37 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 7:22,556,544...22,609,622
Ensembl chr 7:22,573,764...22,609,616 		JBrowse link
G Nup43 nucleoporin 43 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 1:2,144,427...2,157,887
Ensembl chr 1:2,148,043...2,158,186 		JBrowse link
G Nup54 nucleoporin 54 ISO RGD PMID:25184662 RGD:9743947 NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028 		JBrowse link
G Nup58 nucleoporin 58 ISO RGD PMID:25184662 RGD:9743947 NCBI chr15:34,358,170...34,407,160
Ensembl chr15:34,358,277...34,407,060 		JBrowse link
G Nup62 nucleoporin 62 ISO RGD PMID:25184662 RGD:9743947 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174 		JBrowse link
G Nup85 nucleoporin 85 ISO RGD PMID:25184662 RGD:9743947 NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043 		JBrowse link
G Nup98 nucleoporin 98 and 96 precursor ISO RGD PMID:25184662 RGD:9743947 NCBI chr 1:156,494,423...156,591,415
Ensembl chr 1:156,494,423...156,591,415 		JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component ISO RGD PMID:25184662 RGD:9743947 NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173 		JBrowse link
G Seh1l SEH1-like nucleoporin ISO RGD PMID:25184662 RGD:9743947 NCBI chr18:61,346,986...61,369,987
Ensembl chr18:61,332,158...61,458,379 		JBrowse link
CRM1 export pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anp32a acidic nuclear phosphoprotein 32 family member A ISO RGD PMID:23583578 RGD:9743967 NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443 		JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B ISO RGD PMID:23583578 RGD:9743967 NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E ISO RGD PMID:23583578 RGD:9743967 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784 		JBrowse link
G Lrpprc leucine-rich pentatricopeptide repeat containing ISO RGD PMID:23583578 RGD:9743967 NCBI chr 6:9,859,816...9,942,294
Ensembl chr 6:9,859,867...9,942,293 		JBrowse link
G Nup98 nucleoporin 98 and 96 precursor ISO RGD PMID:23583578 RGD:9743967 NCBI chr 1:156,494,423...156,591,415
Ensembl chr 1:156,494,423...156,591,415 		JBrowse link
G Nxf3 nuclear RNA export factor 3 ISO RGD PMID:23583578 RGD:9743967 NCBI chr  X:99,025,901...99,050,409
Ensembl chr  X:99,025,901...99,039,261 		JBrowse link
G Ran RAN, member RAS oncogene family ISO RGD PMID:23583578 RGD:9743967 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276 		JBrowse link
G Ranbp1 RAN binding protein 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838 		JBrowse link
G Ranbp2 RAN binding protein 2 ISO RGD PMID:23583578 RGD:9743967 NCBI chr20:26,984,520...27,036,573
Ensembl chr20:26,442,217...26,493,481 		JBrowse link
G Rangap1 RAN GTPase activating protein 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:113,224,703...113,250,438 		JBrowse link
G Xpo1 exportin 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
NXF1-NXT1 export pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alyref Aly/REF export factor ISO RGD PMID:22178508 RGD:9743960 NCBI chr10:105,871,424...105,875,076
Ensembl chr10:105,871,306...105,875,069 		JBrowse link
G Ddx19b DEAD-box helicase 19B ISO RGD PMID:23583578 RGD:9743967 NCBI chr19:38,968,215...38,998,907
Ensembl chr19:38,968,215...38,997,259 		JBrowse link
G Ddx39b DExD-box helicase 39B ISO RGD PMID:22178508 RGD:9743960 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Gle1 GLE1 RNA export mediator ISO RGD PMID:23583578 RGD:9743967 NCBI chr 3:13,209,312...13,237,018
Ensembl chr 3:13,209,322...13,237,379 		JBrowse link
G Nup214 nucleoporin 214 ISO RGD PMID:23583578 RGD:9743967 NCBI chr 3:15,255,111...15,340,568
Ensembl chr 3:15,255,119...15,340,568 		JBrowse link
G Nxf1 nuclear RNA export factor 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636 		JBrowse link
G Nxt1 nuclear transport factor 2-like export factor 1 ISO RGD PMID:23583578 RGD:9743967 NCBI chr 3:136,108,975...136,111,897
Ensembl chr 3:136,108,862...136,111,907 		JBrowse link
G Sarnp SAP domain containing ribonucleoprotein ISO RGD PMID:22178508 RGD:9743960 NCBI chr 7:1,251,096...1,305,335
Ensembl chr 7:1,251,098...1,305,332 		JBrowse link
G Thoc1 THO complex subunit 1 ISO RGD PMID:22178508 RGD:9743960 NCBI chr18:983,824...1,019,123
Ensembl chr18:983,824...1,019,114 		JBrowse link
G Thoc2 THO complex subunit 2 ISO RGD PMID:22178508 RGD:9743960 NCBI chr  X:120,634,966...120,749,569
Ensembl chr  X:120,634,968...120,749,513 		JBrowse link
G Thoc5 THO complex subunit 5 ISO RGD PMID:22178508 RGD:9743960 NCBI chr14:79,758,805...79,792,718
Ensembl chr14:79,758,917...79,792,718 		JBrowse link
G Thoc6 THO complex subunit 6 ISO RGD PMID:22178508 RGD:9743960 NCBI chr10:12,700,051...12,705,411
Ensembl chr10:12,700,051...12,706,925 		JBrowse link
G Thoc7 THO complex subunit 7 ISO RGD PMID:22178508 RGD:9743960 NCBI chr15:11,262,362...11,277,200
Ensembl chr15:11,262,613...11,277,193 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3866
      transport pathway 469
        RNA transport pathway 152
          mRNA nuclear export pathway 37
            CRM1 export pathway 12
            NXF1-NXT1 export pathway 13
paths to the root