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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:prostaglandin biosynthetic pathway
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Accession:PW:0001532 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis of prostaglandins - a class of eicosanoid prostanoids with several members, exerting a range of important functions in the immune and cardiovascular systems.
Synonyms:related_synonym: prostaglandin biosynthetic process


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prostaglandin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 ISO RGD PMID:23747692 RGD:8552778 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 ISO RGD PMID:23747692 RGD:8552778 NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 TAS RGD PMID:12432932 RGD:8552774 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO RGD PMID:12432932 RGD:8552774 NCBI chr11:46,346,405...46,348,815
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883 		JBrowse link
G Prxl2b peroxiredoxin like 2B ISO RGD PMID:18006499 RGD:8552775 NCBI chr 5:170,744,953...170,747,556 JBrowse link
G Ptgds prostaglandin D2 synthase ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Ptges prostaglandin E synthase ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 3:34,575,643...34,586,987 JBrowse link
G Ptges2 prostaglandin E synthase 2 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 3:36,088,246...36,095,430
Ensembl chr 3:15,690,501...15,697,688 		JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:490,656...508,084 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      lipid metabolic pathway 488
        eicosanoid metabolic pathway 18
          prostanoid metabolic pathway 14
            prostaglandin metabolic pathway 10
              prostaglandin biosynthetic pathway 10
Path 2
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      lipid metabolic pathway 488
        fatty acid metabolic pathway 191
          arachidonic acid metabolic pathway 83
            cyclooxygenase mediated pathway of arachidonic acid metabolism 16
              prostaglandin metabolic pathway 10
                prostaglandin biosynthetic pathway 10
paths to the root