PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: ibuprofen pharmacokinetics pathway
Accession: PW:0001469
browse the term
Definition: The pathway of processing - absorption, distribution, metabolism or elimination - of ibuprofen. The drug is used in the treatment of pain and inflammation. Genetic variations can result in changes in the availability of the drug.
Synonyms: related_synonym: SMP:00590
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
ISO
SMPDB
SMP:00590
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:237,693,094...238,057,596
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Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
ISO
SMPDB
SMP:00590
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
ISO
SMPDB
SMP:00590
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
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Dnajb11
DnaJ heat shock protein family (Hsp40) member B11
ISO
SMPDB
SMP:00590
NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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Erp29
endoplasmic reticulum protein 29
ISO
SMPDB
SMP:00590
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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Hsp90b1
heat shock protein 90 beta family member 1
ISO
SMPDB
SMP:00590
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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Hspa5
heat shock protein family A (Hsp70) member 5
ISO
SMPDB
SMP:00590
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hyou1
hypoxia up-regulated 1
ISO
SMPDB
SMP:00590
NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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Pdia2
protein disulfide isomerase family A, member 2
ISO
SMPDB
SMP:00590
NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931
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Pdia4
protein disulfide isomerase family A, member 4
ISO
SMPDB
SMP:00590
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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Pdia6
protein disulfide isomerase family A, member 6
ISO
SMPDB
SMP:00590
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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Ppib
peptidylprolyl isomerase B
ISO
SMPDB
SMP:00590
NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428
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Ptgs1
prostaglandin-endoperoxide synthase 1
ISO
SMPDB
SMP:00590
NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
SMPDB
SMP:00590
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Sdf2l1
stromal cell-derived factor 2-like 1
ISO
SMPDB
SMP:00590
NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
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Slc22a6
solute carrier family 22 member 6
ISO
SMPDB
SMP:00590
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
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Slc22a8
solute carrier family 22 member 8
ISO
SMPDB
SMP:00590
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
ISO
SMPDB
SMP:00590
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
ISO
SMPDB
SMP:00590
NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a9
UDP glucuronosyltransferase family 1 member A9
ISO
SMPDB
SMP:00590
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt2b7
UDP glucuronosyltransferase family 2 member B7
ISO
SMPDB
SMP:00590
NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all