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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter

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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFF1 ALF transcription elongation factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 7:35,309,172...35,516,777
Ensembl chr 7:35,380,578...35,511,446 		JBrowse link
G AFF4 ALF transcription elongation factor 4 ISO RGD PMID:22895430 RGD:9681740 NCBI chr23:35,693,427...35,782,746
Ensembl chr23:35,699,094...35,782,683 		JBrowse link
G CCNK cyclin K ISO RGD PMID:24050178 RGD:9681735 NCBI chr24:77,436,569...77,466,703
Ensembl chr24:77,436,479...77,467,322 		JBrowse link
G CCNT1 cyclin T1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr11:44,932,774...44,966,412
Ensembl chr11:44,937,350...44,966,018 		JBrowse link
G CCNT2 cyclin T2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr10:19,145,163...19,183,777
Ensembl chr10:19,145,161...19,180,917 		JBrowse link
G CDC73 cell division cycle 73 ISO RGD PMID:20060942 RGD:9588246 NCBI chr25:36,167,482...36,302,918
Ensembl chr25:36,170,134...36,302,812 		JBrowse link
G CDK9 cyclin dependent kinase 9 ISO RGD PMID:24050178 RGD:9681735 NCBI chr12:10,342,240...10,346,792
Ensembl chr12:10,342,801...10,346,502 		JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 1:54,047,922...54,077,049
Ensembl chr 1:54,047,886...54,077,338 		JBrowse link
G EAF1 ELL associated factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr15:60,261,013...60,277,177
Ensembl chr15:60,260,967...60,277,626 		JBrowse link
G EAF2 ELL associated factor 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr22:58,966,640...59,025,158
Ensembl chr22:58,974,409...59,025,143 		JBrowse link
G ELL elongation factor for RNA polymerase II ISO RGD PMID:22895430 RGD:9681740 NCBI chr 6:16,915,878...17,000,275
Ensembl chr 6:16,917,953...17,000,230 		JBrowse link
G ELL2 elongation factor for RNA polymerase II 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 4:89,758,483...89,835,773
Ensembl chr 4:89,762,251...89,835,433 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 ISO RGD PMID:22895430 RGD:9681740 NCBI chr26:39,268,461...39,273,833
Ensembl chr26:39,269,538...39,273,321 		JBrowse link
G GTF2F1 general transcription factor IIF subunit 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 6:5,996,585...6,006,893 JBrowse link
G GTF2F2 general transcription factor IIF subunit 2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 3:23,195,682...23,380,628
Ensembl chr 3:23,212,334...23,384,036 		JBrowse link
G LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr26:31,405,019...31,444,350
Ensembl chr26:31,404,537...31,445,198 		JBrowse link
G MLLT1 MLLT1 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr 6:5,835,483...5,913,096
Ensembl chr 6:5,834,660...5,913,119 		JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 ISO RGD PMID:24354960 RGD:9684851 NCBI chr12:41,736,063...41,776,178
Ensembl chr12:41,738,579...41,776,509 		JBrowse link
G NCBP2 nuclear cap binding protein subunit 2 ISO RGD PMID:24354960 RGD:9684851 NCBI chr15:90,306,640...90,314,293
Ensembl chr15:90,306,640...90,313,019 		JBrowse link
G NELFA negative elongation factor complex member A ISO RGD PMID:24050178 RGD:9681735 NCBI chr27:46,759,742...46,786,835
Ensembl chr27:46,760,707...46,787,090 		JBrowse link
G NELFB negative elongation factor complex member B ISO RGD PMID:24050178 RGD:9681735 NCBI chr12:914,384...933,921 JBrowse link
G NELFCD negative elongation factor complex member C/D ISO RGD PMID:24050178 RGD:9681735 NCBI chr 2:5,146,137...5,159,965
Ensembl chr 2:5,146,575...5,159,883 		JBrowse link
G NELFE negative elongation factor complex member E ISO RGD PMID:24050178 RGD:9681735 NCBI chr17:40,063,298...40,069,714
Ensembl chr17:40,063,755...40,198,451 		JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 6:33,990,552...33,996,673
Ensembl chr 6:33,986,916...33,996,347 		JBrowse link
G RNGTT RNA guanylyltransferase and 5'-phosphatase ISO RGD PMID:24354960 RGD:9684851 NCBI chr13:13,053,741...13,386,479
Ensembl chr13:13,053,405...13,386,481 		JBrowse link
G RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr26:41,523,610...41,589,014
Ensembl chr26:41,522,542...41,588,948 		JBrowse link
G SKIC8 SKI8 subunit of superkiller complex ISO RGD PMID:20060942 RGD:9588246 NCBI chr26:5,037,386...5,062,578
Ensembl chr26:5,037,443...5,053,707 		JBrowse link
G SSRP1 structure specific recognition protein 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 1:15,907,874...15,918,376
Ensembl chr 1:15,908,495...15,918,596 		JBrowse link
G SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr29:21,822,520...21,855,552
Ensembl chr29:21,822,393...21,855,923 		JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr16:35,047,874...35,054,438
Ensembl chr16:35,047,934...35,054,239 		JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr 6:34,052,587...34,086,022
Ensembl chr 6:34,052,577...34,085,782 		JBrowse link
G TCEA1 transcription elongation factor A1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 8:50,048,771...50,104,189
Ensembl chr 8:50,048,474...50,104,130 		JBrowse link
G TCEA2 transcription elongation factor A2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 2:174,158...184,237
Ensembl chr 2:174,134...182,943 		JBrowse link
G TCEA3 transcription elongation factor A3 ISO RGD PMID:24050178 RGD:9681735 NCBI chr20:109,251,247...109,294,071 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4028
    regulatory pathway 2488
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1327
        transcription pathway 922
          RNA polymerase transcription pathway 348
            eukaryotic RNA polymerase transcription pathway 348
              RNA polymerase II transcription pathway 279
                RNA polymerase II transcription elongation pathway 34
paths to the root