Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:codeine and morphine pharmacodynamics pathway
go back to main search page
Accession:PW:0001246 term browser browse the term
Definition:The pathway of codeine/morphine-target interaction and of the biochemical or physiological responses to drug. The drugs are potential ligands for the mu-opioid receptor, a class of opioid receptor. Opioid receptors are G-protein coupled receptors (GPCR) activated by endogenous and also exogenous opioids. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00405;   SMP:00406


GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
codeine and morphine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00405 SMP:00406 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692
JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363
JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00405 SMP:00406 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754
JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00405 SMP:00406 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385
JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00405 SMP:00406
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00405 SMP:00406 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924
JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00405 SMP:00406 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00405 SMP:00406 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO SMPDB SMP:00405 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513
JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00406 NCBI chr15:2,841,377...2,858,192
Ensembl chr15:2,841,255...2,858,202
JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr23:77,587,340...77,591,434 JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00406 NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00405 SMP:00406 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828
JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00405 SMP:00406 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO SMPDB SMP:00406 NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO SMPDB SMP:00406 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431
JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00405 SMP:00406 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212
JBrowse link
G HYOU1 hypoxia up-regulated 1 ISO SMPDB SMP:00406 NCBI chr 1:110,418,497...110,431,636
Ensembl chr 1:110,417,942...110,431,590
JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312
JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00405 NCBI chr28:13,297,566...13,330,023 JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088
JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609
JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 ISO SMPDB SMP:00406 NCBI chr 5:229,523...233,298
Ensembl chr 5:229,607...233,200
JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 ISO SMPDB SMP:00406 NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960
JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 ISO SMPDB SMP:00406 NCBI chr14:96,801,327...96,828,325
Ensembl chr14:96,801,349...96,828,716
JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00405 SMP:00406 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447
JBrowse link
G PPIB peptidylprolyl isomerase B ISO SMPDB SMP:00406 NCBI chr26:19,380,496...19,399,596 JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00405 SMP:00406 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325
JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 ISO SMPDB SMP:00406 NCBI chr19:4,465,795...4,467,882
Ensembl chr19:4,465,797...4,467,761
JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643
JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866
JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00405 SMP:00406 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4028
    drug pathway 383
      nervous system drug pathway 173
        analgesic and/or antipyretic drug pathway 89
          opioid drug pathway 50
            codeine and morphine drug pathway 42
              codeine and morphine pharmacodynamics pathway 42
paths to the root