PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: irinotecan pharmacokinetics pathway
Accession: PW:0001225
browse the term
Definition: The pathway of processing - absorption, distribution, metabolism or elimination - of irinotecan, a drug used in the treatment of several types of cancer. Genetic variations can result in changes in the availability of the drug.
Synonyms: related_synonym: SMP:00600
GViewer not supported for the selected species.
G
ABCB1
ATP binding cassette subfamily B member 1
ISO
SMPDB
SMP:00600
NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274
G
ABCC1
ATP binding cassette subfamily C member 1 (ABCC1 blood group)
ISO
SMPDB
SMP:00600
NCBI chr 5:14,972,589...15,164,594
Ensembl chr 5:14,972,646...15,164,567
G
ABCC2
ATP binding cassette subfamily C member 2
ISO
SMPDB
SMP:00600
NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265
G
ABCG2
ATP binding cassette subfamily G member 2 (JR blood group)
ISO
SMPDB
SMP:00600
NCBI chr 7:36,458,110...36,599,753
G
BCHE
butyrylcholinesterase
ISO
SMPDB
SMP:00600
NCBI chr15:23,708,121...23,778,027
Ensembl chr15:23,708,155...23,778,286
G
CYP3A5
cytochrome P450 family 3 subfamily A member 5
ISO
SMPDB
SMP:00600
NCBI chr28:13,473,649...13,517,905
Ensembl chr28:13,491,483...13,519,507
G
DNAJB11
DnaJ heat shock protein family (Hsp40) member B11
ISO
SMPDB
SMP:00600
NCBI chr15:2,841,377...2,858,192
Ensembl chr15:2,841,255...2,858,202
G
ERP29
endoplasmic reticulum protein 29
ISO
SMPDB
SMP:00600
NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499
G
HSP90B1
heat shock protein 90 beta family member 1
ISO
SMPDB
SMP:00600
NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722
G
HSPA5
heat shock protein family A (Hsp70) member 5
ISO
SMPDB
SMP:00600
NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431
G
HYOU1
hypoxia up-regulated 1
ISO
SMPDB
SMP:00600
NCBI chr 1:110,418,497...110,431,636
Ensembl chr 1:110,417,942...110,431,590
G
LOC103233018
liver carboxylesterase 1
ISO
SMPDB
SMP:00600
NCBI chr 5:41,710,500...41,745,483
G
LOC103246766
cytochrome P450 3A8
ISO
SMPDB
SMP:00600
NCBI chr28:13,297,566...13,330,023
G
PDIA2
protein disulfide isomerase family A member 2
ISO
SMPDB
SMP:00600
NCBI chr 5:229,523...233,298
Ensembl chr 5:229,607...233,200
G
PDIA4
protein disulfide isomerase family A member 4
ISO
SMPDB
SMP:00600
NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960
G
PDIA6
protein disulfide isomerase family A member 6
ISO
SMPDB
SMP:00600
NCBI chr14:96,801,327...96,828,325
Ensembl chr14:96,801,349...96,828,716
G
PPIB
peptidylprolyl isomerase B
ISO
SMPDB
SMP:00600
NCBI chr26:19,380,496...19,399,596
G
SDF2L1
stromal cell derived factor 2 like 1
ISO
SMPDB
SMP:00600
NCBI chr19:4,465,795...4,467,882
Ensembl chr19:4,465,797...4,467,761
G
SLCO1B1
solute carrier organic anion transporter family member 1B1
ISO
SMPDB
SMP:00600
NCBI chr11:20,992,353...21,091,761
Ensembl chr11:21,001,655...21,093,278
G
TOP1
DNA topoisomerase I
ISO
SMPDB
SMP:00600
NCBI chr 2:22,655,085...22,751,082
Ensembl chr 2:22,651,995...22,751,102
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all