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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:Fc epsilon receptor mediated signaling pathway
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Accession:PW:0001151 term browser browse the term
Definition:The signaling cascade initiated by an activated Fc epsilon receptor. Fc receptors are classified by the type of antibody they recognize; thus, Fc epsilon receptors bind IgE antibody.
Synonyms:related_synonym: KEGG:04664;   SMP:00358


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Fc epsilon receptor mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEA KEGG rno:04664 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 IEA KEGG rno:04664 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020 		JBrowse link
G Btk Bruton tyrosine kinase IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:102,016,074...102,055,143 		JBrowse link
G Csf2 colony stimulating factor 2 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Fcer1a Fc epsilon receptor Ia IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr13:88,218,427...88,224,723
Ensembl chr13:88,218,420...88,224,681 		JBrowse link
G Fcer1g Fc epsilon receptor Ig IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G Gab2 GRB2-associated binding protein 2 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 1:160,841,066...161,036,940
Ensembl chr 1:160,841,066...161,036,940 		JBrowse link
G Grb2 growth factor receptor bound protein 2 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138 		JBrowse link
G Hras HRas proto-oncogene, GTPase IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon ISO SMPDB SMP:00358
G Il13 interleukin 13 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il3 interleukin 3 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,906,460...38,908,810 		JBrowse link
G Il4 interleukin 4 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Lat linker for activation of T cells IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:190,367,109...190,372,153 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:19,146,846...19,193,750
Ensembl chr10:19,146,554...19,193,744 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:21,437,084...21,554,461 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:7,389,155...7,398,377 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 IEA KEGG rno:04664 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IEA KEGG rno:04664 NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 IEA KEGG rno:04664 NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307 		JBrowse link
G Mapk13 mitogen activated protein kinase 13 IEA KEGG rno:04664 NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEA KEGG rno:04664 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA KEGG rno:04664 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 1:217,864,855...217,873,934
Ensembl chr 1:217,865,159...217,873,108 		JBrowse link
G Nras NRAS proto-oncogene, GTPase IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta IEA KEGG rno:04664 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta IEA KEGG rno:04664 NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG rno:04664 NCBI chr16:18,699,389...18,708,045
Ensembl chr16:18,699,448...18,709,665 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG rno:04664 NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 IEA KEGG rno:04664 NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539 		JBrowse link
G Pla2g10 phospholipase A2, group X IEA KEGG rno:04664 NCBI chr10:2,104,927...2,117,998
Ensembl chr10:2,104,927...2,116,172 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA IEA KEGG rno:04664 NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964 		JBrowse link
G Pla2g12b phospholipase A2, group XIIB IEA KEGG rno:04664 NCBI chr20:27,910,620...27,931,734
Ensembl chr20:27,913,259...27,932,148 		JBrowse link
G Pla2g1b phospholipase A2 group IB IEA KEGG rno:04664 NCBI chr12:46,802,932...46,814,511
Ensembl chr12:46,802,939...46,813,693 		JBrowse link
G Pla2g2a phospholipase A2 group IIA IEA KEGG rno:04664 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Pla2g2c phospholipase A2, group IIC IEA KEGG rno:04664 NCBI chr 5:156,241,142...156,262,368
Ensembl chr 5:156,242,451...156,264,676 		JBrowse link
G Pla2g2d phospholipase A2, group IID IEA KEGG rno:04664 NCBI chr 5:156,299,374...156,305,816
Ensembl chr 5:156,297,777...156,305,812 		JBrowse link
G Pla2g2f phospholipase A2, group IIF IEA KEGG rno:04664 NCBI chr 5:156,270,077...156,276,464
Ensembl chr 5:156,270,077...156,295,516 		JBrowse link
G Pla2g3 phospholipase A2, group III IEA KEGG rno:04664 NCBI chr14:82,589,908...82,597,542
Ensembl chr14:82,591,862...82,597,542 		JBrowse link
G Pla2g4a phospholipase A2 group 4A IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Pla2g4b phospholipase A2 group IVB IEA KEGG rno:04664 NCBI chr 3:127,458,022...127,467,637
Ensembl chr 3:127,459,273...127,467,637 		JBrowse link
G Pla2g4e phospholipase A2, group IVE IEA KEGG rno:04664 NCBI chr 3:127,586,318...127,652,369
Ensembl chr 3:127,587,027...127,651,868 		JBrowse link
G Pla2g4f phospholipase A2, group IVF IEA KEGG rno:04664 NCBI chr 3:127,702,603...127,720,429
Ensembl chr 3:127,703,841...127,718,348 		JBrowse link
G Pla2g5 phospholipase A2, group V IEA KEGG rno:04664 NCBI chr 5:156,324,628...156,393,065
Ensembl chr 5:156,324,629...156,381,926 		JBrowse link
G Pla2g6 phospholipase A2 group VI IEA KEGG rno:04664 NCBI chr 7:112,731,803...112,771,978
Ensembl chr 7:112,731,803...112,771,609 		JBrowse link
G Plcg1 phospholipase C, gamma 1 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050 		JBrowse link
G Plcg2 phospholipase C, gamma 2 IEA KEGG rno:04664 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684 		JBrowse link
G Prkca protein kinase C, alpha IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcd protein kinase C, delta IEA KEGG rno:04664 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Prkce protein kinase C, epsilon IEA KEGG rno:04664 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Prkcg protein kinase C, gamma IEA KEGG rno:04664 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814 		JBrowse link
G Rac1 Rac family small GTPase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA KEGG rno:04664 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 IEA KEGG rno:04664 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:93,778,971...93,892,811 		JBrowse link
G Syk spleen associated tyrosine kinase IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278 		JBrowse link
G Tnf tumor necrosis factor IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 IEA KEGG rno:04664 NCBI chr 9:2,248,856...2,295,905
Ensembl chr 9:2,248,914...2,296,922 		JBrowse link
G Vav2 vav guanine nucleotide exchange factor 2 IEA KEGG rno:04664 NCBI chr 3:30,982,754...31,152,116
Ensembl chr 3:30,982,754...31,152,116 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 IEA
ISO 		KEGG
SMPDB		 SMP:00358 rno:04664 NCBI chr 2:199,699,861...200,042,344
Ensembl chr 2:199,700,445...200,042,343 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      signaling pathway pertinent to immunity 793
        signaling pathway in the adaptive immune response 209
          Fc receptor mediated signaling pathway 130
            Fc epsilon receptor mediated signaling pathway 77
paths to the root