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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:forkhead class A signaling pathway
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Accession:PW:0000958 term browser browse the term
Definition:The signaling pathway mediated by the FoxA subgroup of forkhead family of transcription factors plays important roles in development and in modulating steroid hormone signaling. Three FoxA genes carry out overlapping yet distinct functions. FOXA1 appears to modulate steroid receptor activity in breast and prostate cancer.
Synonyms:related_synonym: FoxA signaling pathway;   PID:200087;   PID:200226


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forkhead class A signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO PID PID:200087 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain ISO PID PID:200087 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain ISO PID PID:200087 NCBI chr10:55,231,558...55,236,786
Ensembl chr10:55,231,440...55,236,750 		JBrowse link
G Afp alpha-fetoprotein ISO PID PID:200087 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO PID PID:200087 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 ISO PID PID:200087 NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642 		JBrowse link
G Alb albumin ISO PID PID:200087 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO PID PID:200087 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740 		JBrowse link
G Ap1b1 adaptor related protein complex 1 subunit beta 1 ISO PID PID:200226 NCBI chr14:84,093,529...84,144,835
Ensembl chr14:84,093,559...84,144,892 		JBrowse link
G Apoa1 apolipoprotein A1 ISO PID PID:200087 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apob apolipoprotein B ISO PID PID:200226 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Ar androgen receptor ISO PID PID:200226 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO PID PID:200226 NCBI chr11:37,368,045...37,375,721
Ensembl chr11:37,368,042...37,375,466 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 ISO PID PID:200087 NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636 		JBrowse link
G Brca1 BRCA1, DNA repair associated ISO PID PID:200226 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763 		JBrowse link
G C4bpb complement component 4 binding protein, beta ISO PID PID:200226 NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO PID PID:200226 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha ISO PID PID:200087 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO PID PID:200087 PID:200226 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta ISO PID PID:200087 NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain ISO PID PID:200226 NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A ISO PID PID:200087 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B ISO PID PID:200087 NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036 		JBrowse link
G Cpt1c carnitine palmitoyltransferase 1c ISO PID PID:200087 NCBI chr 1:104,579,297...104,593,824
Ensembl chr 1:104,579,298...104,593,763 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO PID PID:200087 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crebbp CREB binding protein ISO PID PID:200226 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 ISO PID PID:200226 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 ISO PID PID:200087 NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529 		JBrowse link
G Dscam DS cell adhesion molecule ISO PID PID:200226 NCBI chr11:49,391,385...49,976,861
Ensembl chr11:49,347,531...49,976,238 		JBrowse link
G Ep300 E1A binding protein p300 ISO PID PID:200226 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Esr1 estrogen receptor 1 ISO PID PID:200226 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G F2 coagulation factor II, thrombin ISO PID PID:200087 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200226 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Foxa1 forkhead box A1 ISO PID PID:200087 PID:200226 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191 		JBrowse link
G Foxa2 forkhead box A2 ISO PID PID:200087 PID:200226 NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757 		JBrowse link
G Foxa3 forkhead box A3 ISO PID PID:200087 PID:200226 NCBI chr 1:87,790,111...87,800,259
Ensembl chr 1:87,790,012...87,800,953 		JBrowse link
G Foxf1 forkhead box F1 ISO PID PID:200087 NCBI chr19:66,062,635...66,066,427
Ensembl chr19:66,062,369...66,066,428 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 ISO PID PID:200087 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G Gcg glucagon ISO PID PID:200226 NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:67,522,489...67,531,533 		JBrowse link
G Gck glucokinase ISO PID PID:200087 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase ISO PID PID:200087 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO PID PID:200087 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hnf1a HNF1 homeobox A ISO PID PID:200087 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755 		JBrowse link
G Hnf1b HNF1 homeobox B ISO PID PID:200087 NCBI chr10:69,233,377...69,287,360
Ensembl chr10:69,233,131...69,287,361 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha ISO PID PID:200087 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO PID PID:200087 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344 		JBrowse link
G Ins2 insulin 2 ISO PID PID:200087 PID:200226 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200226 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO PID PID:200087 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 ISO PID PID:200226 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO PID PID:200226 NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:175,157,821...175,240,631 		JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 ISO PID PID:200226 NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847
Ensembl chr20:48,468,224...48,488,847 		JBrowse link
G Nf1 neurofibromin 1 ISO PID PID:200087 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,804,266...65,034,946 		JBrowse link
G Nfia nuclear factor I/A ISO PID PID:200226 NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395 		JBrowse link
G Nfib nuclear factor I/B ISO PID PID:200226 NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945 		JBrowse link
G Nfic nuclear factor I/C ISO PID PID:200226 NCBI chr 7:8,928,423...8,963,455
Ensembl chr 7:8,904,117...8,963,409 		JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO PID PID:200087 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:79,731,677...79,736,441 		JBrowse link
G Nkx3-1 NK3 homeobox 1 ISO PID PID:200226 NCBI chr15:50,883,661...50,886,253
Ensembl chr15:50,883,597...50,886,251 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 ISO PID PID:200226 NCBI chr 1:133,419,161...133,434,290
Ensembl chr 1:133,420,227...133,431,975 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO PID PID:200087 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO PID PID:200226 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 ISO PID PID:200087 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO PID PID:200087 NCBI chr12:12,793,957...12,799,156
Ensembl chr12:12,793,957...12,799,156 		JBrowse link
G Pisd phosphatidylserine decarboxylase ISO PID PID:200226 NCBI chr14:82,166,401...82,215,479
Ensembl chr14:82,166,412...82,215,913 		JBrowse link
G Pklr pyruvate kinase L/R ISO PID PID:200087 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 ISO PID PID:200226 NCBI chr13:80,653,602...80,796,279
Ensembl chr13:80,663,714...80,796,356 		JBrowse link
G Prdm15 PR/SET domain 15 ISO PID PID:200226 NCBI chr11:50,633,973...50,691,624
Ensembl chr11:50,633,973...50,691,823 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO PID PID:200226 NCBI chr 1:215,406,138...215,409,686
Ensembl chr 1:215,406,138...215,409,686 		JBrowse link
G Serpina1 serpin family A member 1 ISO PID PID:200226 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703 		JBrowse link
G Sftpa1 surfactant protein A1 ISO PID PID:200226 NCBI chr16:17,042,264...17,045,770
Ensembl chr16:17,042,255...17,045,769 		JBrowse link
G Sftpd surfactant protein D ISO PID PID:200226 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,080,567...17,094,036 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO PID PID:200226 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO PID PID:200087 NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467 		JBrowse link
G Sod1 superoxide dismutase 1 ISO PID PID:200226 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sp1 Sp1 transcription factor ISO PID PID:200087 PID:200226 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513 		JBrowse link
G Tat tyrosine aminotransferase ISO PID PID:200087 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482 		JBrowse link
G Tff1 trefoil factor 1 ISO PID PID:200226 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956 		JBrowse link
G Tfrc transferrin receptor ISO PID PID:200087 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Ttr transthyretin ISO PID PID:200087 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:12,216,732...12,225,969 		JBrowse link
G Ucp2 uncoupling protein 2 ISO PID PID:200087 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743 		JBrowse link
G Vtn vitronectin ISO PID PID:200226 NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860 		JBrowse link
G Xbp1 X-box binding protein 1 ISO PID PID:200226 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      transcription factor mediated signaling pathway 445
        forkhead signaling pathway 82
          forkhead class A signaling pathway 82
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3866
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1738
        transcription pathway 1059
          transcription pathway via transcription factor mediated signaling 445
            forkhead signaling pathway 82
              forkhead class A signaling pathway 82
paths to the root