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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:epinephrine biosynthetic pathway
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Accession:PW:0000803 term browser browse the term
Definition:Those metabolic reactions involved in the biosynthesis of epinephrine. Epinephrine is primarily synthesized in adrenal chromaffin cells in response to specific stresses that activate the sympatho-adreno-medullary system.
Synonyms:related_synonym: epinephrine biosynthetic process
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epinephrine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316 		JBrowse link
G Ddc dopa decarboxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IDA
ISO 		RGD PMID:7914070 PMID:19342614 RGD:4139902, RGD:4139904 NCBI chr10:83,881,211...83,882,849
Ensembl chr10:83,881,185...83,882,849 		JBrowse link
G Qdpr quinoid dihydropteridine reductase ISO RGD PMID:19342614 RGD:4139904 NCBI chr14:69,882,776...69,896,378
Ensembl chr14:69,882,612...69,896,379 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 IDA RGD PMID:19903816 RGD:5128868 NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231 		JBrowse link
G Th tyrosine hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      biogenic amines and polyamines metabolic pathway 28
        catecholamine metabolic pathway 6
          epinephrine metabolic pathway 6
            epinephrine biosynthetic pathway 6
Path 2
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      metabolic pathway pertinent to the brain 131
        neurotransmitter metabolic pathway 34
          amine neurotransmitter metabolic pathway 8
            catecholamine metabolic pathway 6
              catecholamine biosynthetic pathway 6
                epinephrine biosynthetic pathway 6
paths to the root