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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:fatty acid beta degradation pathway
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Accession:PW:0000738 term browser browse the term
Definition:Fatty acid degradation via beta oxidation, the most common fatty acid degradation pathway, occurs in four reactions resulting in the formation of acetyl-CoA and a fatty acyl-CoA two carbon shorter than the one that began the cycle. Acetyl-CoA can undergo further oxidation via the Krebs cycle or can be converted to ketone bodies.
Synonyms:related_synonym: SMP:00052;   SMP:00480;   SMP:00481;   SMP:00482;   fatty acid beta oxidation pathway
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fatty acid beta degradation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISO SMPDB SMP:00052 NCBI chr  X:156,579,669...156,601,448
Ensembl chr  X:156,579,785...156,601,446 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 ISO SMPDB SMP:00052 NCBI chr 7:124,142,597...124,191,202
Ensembl chr 7:124,142,595...124,191,202 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 IDA
ISO 		SMPDB
RGD		 PMID:11879205 SMP:00480 SMP:00481 SMP:00482, RGD:2317624 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420 		JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 ISO RGD PMID:14728676 RGD:2317589 NCBI chr 2:120,871,329...120,894,306
Ensembl chr 2:120,871,227...120,894,709 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain ISO
IDA 		SMPDB
RGD		 PMID:14728676 PMID:3968063 SMP:00480 SMP:00482, RGD:2317589, RGD:2317678 NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain ISO
IDA 		SMPDB
RGD		 PMID:14728676 PMID:3968063 SMP:00481, RGD:2317589, RGD:2317678 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain ISO
IDA 		SMPDB
RGD		 PMID:14728676 PMID:3968063 SMP:00480, RGD:2317589, RGD:2317678 NCBI chr12:47,154,259...47,163,580
Ensembl chr12:47,154,276...47,164,103 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain ISO
IMP 		RGD PMID:14728676 PMID:15850553 RGD:2317589, RGD:2317683 NCBI chr10:55,231,558...55,236,786
Ensembl chr10:55,231,440...55,236,750 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 ISO SMPDB SMP:00480 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 ISO SMPDB
RGD		 PMID:17762044 SMP:00052 SMP:00482, RGD:2317576 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:87,563,601...87,613,097 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO RGD PMID:17762044 RGD:2317576 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:110,739,648...110,803,261 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 ISO RGD PMID:17762044 RGD:2317576 NCBI chr10:38,940,668...38,999,515
Ensembl chr10:38,940,747...39,002,873 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 ISO SMPDB SMP:00481 NCBI chr 1:183,417,052...183,451,897
Ensembl chr 1:183,416,009...183,454,217 		JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 1:183,347,705...183,386,453
Ensembl chr 1:183,347,705...183,386,453 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437 		JBrowse link
G Acsm4 acyl-CoA synthetase medium-chain family member 4 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 1:183,485,259...183,509,712
Ensembl chr 1:183,485,259...183,509,712 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:159,910,809...159,960,748 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 ISO RGD PMID:17762044 RGD:2317576 NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830 		JBrowse link
G Acss3 acyl-CoA synthetase short-chain family member 3 ISO SMPDB SMP:00480 NCBI chr 7:44,127,725...44,336,707
Ensembl chr 7:44,127,122...44,336,684 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A TAS
ISO 		SMPDB
RGD		 PMID:19430727 SMP:00482, RGD:2317584 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B ISO RGD PMID:19430727 RGD:2317584 NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 TAS
ISO 		SMPDB
RGD		 PMID:19430727 SMP:00052 SMP:00482, RGD:2317584 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818 		JBrowse link
G Crat carnitine O-acetyltransferase ISO SMPDB SMP:00052 NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099 		JBrowse link
G Crot carnitine O-octanoyltransferase ISO SMPDB SMP:00052 NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 IMP
ISO 		SMPDB
RGD		 PMID:12379132 SMP:00480 SMP:00481 SMP:00482, RGD:2317616 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha ISO RGD PMID:14728676 RGD:2317589 NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:64,731,193...64,788,080 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta ISO RGD PMID:14728676 RGD:2317589 NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659 		JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase ISO RGD PMID:14728676 RGD:2317589 NCBI chr 2:167,038,707...167,060,758
Ensembl chr 2:167,025,823...167,060,770 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IMP
ISO 		SMPDB
RGD		 PMID:17491019 SMP:00480 SMP:00481 SMP:00482, RGD:2302227 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO SMPDB
RGD		 PMID:10816122 SMP:00481 SMP:00482, RGD:2317625 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta ISO SMPDB
RGD		 PMID:10816122 SMP:00481 SMP:00482, RGD:2317625 NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO SMPDB SMP:00480 NCBI chr  X:24,568,551...24,571,012
Ensembl chr  X:24,568,551...24,574,681 		JBrowse link
G Pex11g peroxisomal biogenesis factor 11 gamma ISO SMPDB SMP:00052 NCBI chr12:6,301,461...6,329,741
Ensembl chr12:6,277,664...6,318,919 		JBrowse link
G Pex13 peroxisomal biogenesis factor 13 ISO SMPDB SMP:00052 NCBI chr14:101,804,673...101,822,367
Ensembl chr14:101,804,673...101,822,367 		JBrowse link
G Pex14 peroxisomal biogenesis factor 14 ISO SMPDB SMP:00052 NCBI chr 5:164,682,876...164,819,352
Ensembl chr 5:164,682,715...164,819,352 		JBrowse link
G Slc25a20 solute carrier family 25 member 20 ISO SMPDB
RGD		 PMID:19430727 SMP:00052 SMP:00481 SMP:00482, RGD:2317584 NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:118,243,519...118,265,027 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      lipid metabolic pathway 488
        fatty acid metabolic pathway 191
          fatty acid degradation pathway 42
            fatty acid beta degradation pathway 38
              propionyl-CoA degradation pathway 0
              very long-chain fatty acid beta degradation pathway 0
paths to the root