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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:altered glycoconjugated protein signaling pathway
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Accession:PW:0000670 term browser browse the term
Definition:A glycoconjugated protein signaling pathway that deviates from what its normal course should be.



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altered Notch signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 ISS RGD PMID:10079256 RGD:1304492 NCBI chr 6:170,282,200...170,291,078
Ensembl chr 6:170,282,206...170,306,565
JBrowse link
G DLL3 delta like canonical Notch ligand 3 ISS RGD PMID:12141422 RGD:1304493 NCBI chr19:39,498,947...39,508,469
Ensembl chr19:39,498,895...39,508,481
JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 TAS RGD PMID:12548545 RGD:1334460 NCBI chr 8:79,764,010...79,767,767
Ensembl chr 8:79,762,371...79,767,857
JBrowse link
G JAG2 jagged canonical Notch ligand 2 ISS RGD PMID:10079256 RGD:1304492 NCBI chr14:105,140,981...105,168,776
Ensembl chr14:105,140,982...105,168,824
JBrowse link
G NOTCH1 notch receptor 1 ISS RGD PMID:11900468 RGD:724389 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NUMB NUMB endocytic adaptor protein IDA RGD PMID:15492044 RGD:1334451 NCBI chr14:73,275,216...73,458,546
Ensembl chr14:73,275,107...73,458,617
JBrowse link
altered Notch signaling pathway involving promoters term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 TAS RGD PMID:12548545 RGD:1334460 NCBI chr 8:79,764,010...79,767,767
Ensembl chr 8:79,762,371...79,767,857
JBrowse link
altered Notch signaling pathway involving the macromolecules modifying the main players term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUMB NUMB endocytic adaptor protein IDA RGD PMID:15492044 RGD:1334451 NCBI chr14:73,275,216...73,458,546
Ensembl chr14:73,275,107...73,458,617
JBrowse link
G PSEN2 presenilin 2 IMP C. elegans transgenics expressing wild-type and mutant PSEN2 RGD PMID:16474849 RGD:2302525 NCBI chr 1:226,870,594...226,903,829
Ensembl chr 1:226,870,184...226,927,726
JBrowse link
altered Notch signaling pathway involving the main players term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL3 delta like canonical Notch ligand 3 TAS Mutations in the gene have been associated with Spondylocostal dysostosis RGD PMID:12141422 RGD:1304493 NCBI chr19:39,498,947...39,508,469
Ensembl chr19:39,498,895...39,508,481
JBrowse link
G JAG1 jagged canonical Notch ligand 1 TAS RGD PMID:15057910 RGD:1334443 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
JBrowse link
G NOTCH1 notch receptor 1 IDA Mutations in the dimerization and/or PEST domain have been associated with human acute T-lymphoblastic leukemias RGD PMID:15472075 RGD:1334450 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NOTCH3 notch receptor 3 IDA Mutations are predominantly found in the EGF repeats and clustered within the first five RGD PMID:9388399 RGD:1334441 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
JBrowse link
altered Reelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB1 DAB adaptor protein 1 TAS RGD PMID:12764038 RGD:1358468 NCBI chr 1:56,994,778...58,546,726
Ensembl chr 1:56,994,778...58,546,734
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:12778121 RGD:2324970 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G ITGA3 integrin subunit alpha 3 ISO RGD PMID:15583703 RGD:2325851 NCBI chr17:50,056,065...50,090,481
Ensembl chr17:50,055,968...50,090,481
JBrowse link
G ITGB1 integrin subunit beta 1 ISO RGD PMID:15583703 RGD:2325851 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
G LRP8 LDL receptor related protein 8 TAS RGD PMID:19846452 RGD:2324974 NCBI chr 1:53,242,364...53,328,070
Ensembl chr 1:53,242,364...53,328,469
JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 ISO RGD PMID:17330141 RGD:4107040 NCBI chr17:2,593,210...2,685,617
Ensembl chr17:2,593,210...2,685,615
JBrowse link
G PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 ISO RGD PMID:17330141 RGD:4107040 NCBI chr11:117,144,287...117,178,173
Ensembl chr11:117,144,284...117,176,894
JBrowse link
G PAFAH1B3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 ISO RGD PMID:17330141 RGD:4107040 NCBI chr19:42,297,033...42,302,800
Ensembl chr19:42,297,033...42,303,546
JBrowse link
G RELN reelin ISS RGD PMID:12764038 RGD:1358468 NCBI chr 7:103,471,789...103,989,658
Ensembl chr 7:103,471,381...103,989,658
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase TAS RGD PMID:18237558 RGD:2325284 NCBI chr20:37,344,690...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G VLDLR very low density lipoprotein receptor TAS RGD PMID:12764038 RGD:1358468 NCBI chr 9:2,621,786...2,660,056
Ensembl chr 9:2,621,182...2,660,056
JBrowse link
altered Wnt signaling, canonical pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway TAS RGD PMID:18432252 RGD:2293188 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G AXIN1 axin 1 TAS RGD PMID:18432252 RGD:2293188 NCBI chr16:287,440...355,226
Ensembl chr16:287,440...352,723
JBrowse link
G AXIN2 axin 2 TAS RGD PMID:18432252 RGD:2293188 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648
JBrowse link
G CTNNB1 catenin beta 1 TAS RGD PMID:18432252 PMID:19078924 RGD:2293188, RGD:4143515 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G LRP5 LDL receptor related protein 5 TAS RGD PMID:18432252 RGD:2293188 NCBI chr11:68,298,866...68,449,275
Ensembl chr11:68,312,591...68,449,275
JBrowse link
G TCF7L2 transcription factor 7 like 2 IMP RGD PMID:18772397 RGD:5490966 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678
JBrowse link
G WNT9A Wnt family member 9A IMP RGD PMID:18772397 RGD:5490966 NCBI chr 1:227,918,656...227,947,932
Ensembl chr 1:227,918,656...227,947,932
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    signaling pathway 2503
      glycoconjugated protein signaling pathway 413
        altered glycoconjugated protein signaling pathway 27
          altered glycoprotein signaling pathway + 27
paths to the root