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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:phosphatase mediated signaling pathway
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Accession:PW:0000652 term browser browse the term
Definition:Phosphatases are essential components of biological pathways. Phosphorylaton by protein kinases and dephosphorylation by protein phosphatases exert major regulatory roles. In addition, they can also initiate signaling cascades.


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calcineurin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfatc2 nuclear factor of activated T-cells 2 ISO RGD PMID:15336966 RGD:1579951 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 ISO RGD PMID:15336966 RGD:1579951 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 ISO RGD PMID:15336966 RGD:1579951 NCBI chr15:34,493,163...34,502,238
Ensembl chr15:34,493,138...34,504,326
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta ISO RGD PMID:15336966 RGD:1579951 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:15336966 RGD:1579951 NCBI chr15:51,896,427...51,968,075
Ensembl chr15:51,896,615...51,967,897
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta ISO RGD PMID:15336966 RGD:1579951 NCBI chr 5:64,945,583...64,946,578
Ensembl chr 5:64,945,583...64,946,580
JBrowse link
G Rcan1 regulator of calcineurin 1 ISO RGD PMID:16415348 RGD:1581652 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6103
    signaling pathway 2646
      phosphatase mediated signaling pathway 9
        altered phosphatase mediated signaling pathway + 0
        serine/threonine-specific phosphatase mediated signaling pathway + 9
        tyrosine-specific phosphatase mediated signaling pathway 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.