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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:signaling pathway involving second messengers
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Accession:PW:0000541 term browser browse the term



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adenosine monophosphate-activated protein kinase (AMPK) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cab39 calcium binding protein 39 TAS
IDA
RGD PMID:15509864 PMID:14511394 RGD:1600678, RGD:1600691 NCBI chr 9:86,463,008...86,524,545
Ensembl chr 9:86,463,095...86,524,544
JBrowse link
G Calm1 calmodulin 1 ISO RGD PMID:16054095 RGD:2311420 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 ISO RGD PMID:16054095 RGD:2311420 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 ISO RGD PMID:16054095 RGD:2311420 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 IDA RGD PMID:16054095 RGD:2311420 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 IDA RGD PMID:16054095 RGD:2311420 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A IEP RGD PMID:30868489 RGD:25823184 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Ppm1e protein phosphatase, Mg2+/Mn2+ dependent, 1E ISO RGD PMID:20801214 RGD:7794756 NCBI chr10:72,051,643...72,187,439
Ensembl chr10:72,055,208...72,187,282
JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F ISO RGD PMID:20801214 RGD:7794756 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:21782450 RGD:7794757 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta ISO RGD PMID:21782450 RGD:7794757 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp1r3d protein phosphatase 1, regulatory subunit 3D ISO RGD PMID:21782450 RGD:7794757 NCBI chr 3:165,502,384...165,505,455
Ensembl chr 3:165,502,384...165,505,455
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:21782450 RGD:7794757 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO
IDA
RGD PMID:15509864 PMID:14511394 PMID:12829246 RGD:1600678, RGD:1600691, RGD:1600679 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 ISO
IDA
RGD PMID:15509864 PMID:14511394 PMID:12829246 RGD:1600678, RGD:1600691, RGD:1600679 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 ISO RGD PMID:15509864 PMID:12829246 RGD:1600678, RGD:1600679 NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 ISO RGD PMID:15509864 PMID:12829246 RGD:1600678, RGD:1600679 NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872
JBrowse link
G Prkag1 protein kinase AMP-activated non-catalytic subunit gamma 1 ISO
IDA
RGD PMID:15509864 PMID:14511394 PMID:12829246 RGD:1600678, RGD:1600691, RGD:1600679 NCBI chr 7:129,963,105...129,980,532
Ensembl chr 7:129,963,105...129,980,561
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO RGD PMID:15509864 PMID:12829246 RGD:1600678, RGD:1600679 NCBI chr 4:10,010,574...10,252,152
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
G Prkag3 protein kinase AMP-activated non-catalytic subunit gamma 3 ISO RGD PMID:15509864 PMID:12829246 RGD:1600678, RGD:1600679 NCBI chr 9:76,295,715...76,304,959
Ensembl chr 9:76,295,715...76,304,959
JBrowse link
G Stk11 serine/threonine kinase 11 TAS
IDA
RGD PMID:15509864 PMID:14511394 RGD:1600678, RGD:1600691 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Strada STE20 related adaptor alpha TAS
IDA
RGD PMID:15509864 PMID:14511394 RGD:1600678, RGD:1600691 NCBI chr10:91,094,849...91,123,890
Ensembl chr10:91,094,687...91,123,830
JBrowse link
G Tsc1 TSC complex subunit 1 IEP RGD PMID:31787541 RGD:25823196 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674
JBrowse link
altered phosphatidylinositol 3-kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO RGD PMID:23759327 RGD:8693397 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pten phosphatase and tensin homolog ISO RGD PMID:23759327 RGD:8693397 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
altered phosphatidylinositol 3-kinase-Akt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:18955974 PMID:21277552 RGD:2313763, RGD:5133243 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:18955974 PMID:15166380 PMID:19506583 RGD:2313763, RGD:2313408, RGD:5490965 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 ISO RGD PMID:18955974 RGD:2313763 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO RGD PMID:18955974 PMID:21277552 PMID:20951313 PMID:19078924 RGD:2313763, RGD:5133243, RGD:5133242, RGD:4143515 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pten phosphatase and tensin homolog ISO RGD PMID:18955974 PMID:19506583 PMID:20951313 PMID:19078924 PMID:18008377 RGD:2313763, RGD:5490965, RGD:5133242, RGD:4143515, RGD:2326139 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
ceramide signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 ISO PID PID:200119 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEA KEGG rno:05212 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 IEA KEGG rno:05212 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 IEA KEGG rno:05212 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 ISO PID PID:200119 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Bad BCL2-associated agonist of cell death ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag4 BAG cochaperone 4 ISO PID PID:200119 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO PID PID:200119 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO PID PID:200119 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 IEA KEGG rno:05212 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist ISO PID PID:200119 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 ISO PID PID:200119 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase IEA KEGG rno:05212 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Brca2 BRCA2, DNA repair associated IEA KEGG rno:05212 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Casp8 caspase 8 ISO PID PID:200119 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 IEA KEGG rno:05212 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccnd1 cyclin D1 IEA KEGG rno:05212 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdc42 cell division cycle 42 IEA KEGG rno:05212 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdk4 cyclin-dependent kinase 4 IEA KEGG rno:05212 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 IEA KEGG rno:05212 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A IEA KEGG rno:05212 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex IEA KEGG rno:05212 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain ISO PID PID:200119 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Ctsd cathepsin D ISO PID PID:200119 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cycs cytochrome c, somatic ISO PID PID:200119 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G E2f1 E2F transcription factor 1 IEA KEGG rno:05212 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f3 E2F transcription factor 3 IEA KEGG rno:05212 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G Egf epidermal growth factor ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor IEA KEGG rno:05212 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A ISO PID PID:200119 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 ISO PID PID:200119 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IEA KEGG rno:05212 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fadd Fas associated via death domain ISO PID PID:200119 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Igf1 insulin-like growth factor 1 ISO PID PID:200119 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IEA KEGG rno:05212 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma IEA KEGG rno:05212 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Jak1 Janus kinase 1 IEA KEGG rno:05212 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Kras KRAS proto-oncogene, GTPase IEA KEGG rno:05212 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Ksr1 kinase suppressor of ras 1 ISO PID PID:200119 NCBI chr10:63,961,771...64,098,076
Ensembl chr10:63,961,759...64,098,076
JBrowse link
G Madd MAP-kinase activating death domain ISO PID PID:200119 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO PID PID:200119 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO PID PID:200119 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200119 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 ISO PID PID:200119 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk10 mitogen activated protein kinase 10 IEA KEGG rno:05212 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA KEGG rno:05212 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO PID PID:200119 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha ISO PID PID:200119 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor ISO PID PID:200119 NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627
JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO PID PID:200119 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO PID PID:200119 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pgf placental growth factor IEA KEGG rno:05212 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha IEA KEGG rno:05212 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta IEA KEGG rno:05212 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta IEA KEGG rno:05212 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA KEGG rno:05212 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG rno:05212 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG rno:05212 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 IEA KEGG rno:05212 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Pld1 phospholipase D1 IEA KEGG rno:05212 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Prkcd protein kinase C, delta ISO PID PID:200119 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkcz protein kinase C, zeta ISO PID PID:200119 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 ISO PID PID:200119 NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347
JBrowse link
G Rac1 Rac family small GTPase 1 IEA KEGG rno:05212 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rac2 Rac family small GTPase 2 IEA KEGG rno:05212 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Rad51 RAD51 recombinase IEA KEGG rno:05212 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rala RAS like proto-oncogene A IEA KEGG rno:05212 NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063
JBrowse link
G Ralb RAS like proto-oncogene B IEA KEGG rno:05212 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
JBrowse link
G Ralbp1 ralA binding protein 1 IEA KEGG rno:05212 NCBI chr 9:105,456,425...105,492,711
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator IEA KEGG rno:05212 NCBI chr 3:11,839,686...11,880,059
Ensembl chr 3:11,839,416...11,880,059
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO
IEA
PID
KEGG
PID:200119 rno:05212 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO PID PID:200119 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Smad2 SMAD family member 2 IEA KEGG rno:05212 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 IEA KEGG rno:05212 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 IEA KEGG rno:05212 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 ISO PID PID:200119 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO PID PID:200119 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Sphk2 sphingosine kinase 2 ISO PID PID:200119 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA KEGG rno:05212 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat3 signal transducer and activator of transcription 3 IEA KEGG rno:05212 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tgfa transforming growth factor alpha IEA KEGG rno:05212 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEA KEGG rno:05212 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEA KEGG rno:05212 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IEA KEGG rno:05212 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IEA KEGG rno:05212 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEA KEGG rno:05212 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tnf tumor necrosis factor ISO PID PID:200119 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO PID PID:200119 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tp53 tumor protein p53 IEA KEGG rno:05212 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tradd TNFRSF1A-associated via death domain ISO PID PID:200119 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO PID PID:200119 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Vegfa vascular endothelial growth factor A IEA KEGG rno:05212 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfb vascular endothelial growth factor B IEA KEGG rno:05212 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link
G Vegfc vascular endothelial growth factor C IEA KEGG rno:05212 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Vegfd vascular endothelial growth factor D IEA KEGG rno:05212 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295
JBrowse link
phosphatidylinositol 3-kinase class I signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adap1 ArfGAP with dual PH domains 1 ISO PID PID:200116 NCBI chr12:15,323,913...15,376,110
Ensembl chr12:15,324,209...15,380,831
JBrowse link
G Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 ISO PID PID:200116 NCBI chr18:29,806,214...29,834,217
Ensembl chr18:29,807,536...29,833,555
JBrowse link
G Arf1 ADP-ribosylation factor 1 ISO PID PID:200116 NCBI chr10:43,997,983...44,014,543
Ensembl chr10:43,997,986...44,014,434
JBrowse link
G Arf5 ADP-ribosylation factor 5 ISO PID PID:200116 NCBI chr 4:57,038,521...57,041,447
Ensembl chr 4:57,038,521...57,041,441
JBrowse link
G Arf6 ADP-ribosylation factor 6 ISO PID PID:200116 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase ISO PID PID:200116 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Blnk B-cell linker ISO PID PID:200116 NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113
JBrowse link
G Btk Bruton tyrosine kinase ISO PID PID:200116 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Cyth1 cytohesin 1 ISO PID PID:200116 NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
JBrowse link
G Cyth2 cytohesin 2 ISO PID PID:200116 NCBI chr 1:96,284,252...96,291,090
Ensembl chr 1:96,284,252...96,291,092
JBrowse link
G Cyth3 cytohesin 3 ISO PID PID:200116 NCBI chr12:10,840,137...10,933,792
Ensembl chr12:10,840,157...10,933,812
JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 ISO PID PID:200116 NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISO PID PID:200116 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
JBrowse link
G Foxo3 forkhead box O3 ISO PID PID:200116 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO PID PID:200116 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase ISO PID PID:200116 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO PID PID:200116 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO PID PID:200116 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO PID PID:200116 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 ISO PID PID:200116 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Itk IL2-inducible T-cell kinase ISO PID PID:200116 NCBI chr10:30,753,339...30,814,685
Ensembl chr10:30,753,344...30,814,685
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase ISO PID PID:200116 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO PID PID:200116 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO PID PID:200116 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO PID PID:200116 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO PID PID:200116 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta ISO PID PID:200116 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta ISO PID PID:200116 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO PID PID:200116 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200116 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 ISO PID PID:200116 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 ISO PID PID:200116 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 ISO PID PID:200116 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 ISO PID PID:200116 NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243
JBrowse link
G Plcg1 phospholipase C, gamma 1 ISO PID PID:200116 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plcg2 phospholipase C, gamma 2 ISO PID PID:200116 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 ISO PID PID:200116 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
JBrowse link
G Plekha2 pleckstrin homology domain containing A2 ISO PID PID:200116 NCBI chr16:66,938,684...67,000,661 JBrowse link
G Pten phosphatase and tensin homolog ISO PID PID:200116 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rac1 Rac family small GTPase 1 ISO PID PID:200116 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO PID PID:200116 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rhoa ras homolog family member A ISO PID PID:200116 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 ISO PID PID:200116 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200116 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Syk spleen associated tyrosine kinase ISO PID PID:200116 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase ISO PID PID:200116 NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 ISO PID PID:200116 NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700
JBrowse link
phosphatidylinositol 3-kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IEA KEGG rno:04070 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 IEA KEGG rno:04070 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 IEA KEGG rno:04070 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Calml3 calmodulin-like 3 IEA KEGG rno:04070 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
JBrowse link
G Calml5 calmodulin-like 5 IEA KEGG rno:04070 NCBI chr17:66,394,433...66,395,390 JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase IEA KEGG rno:04070 NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408
JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 IEA KEGG rno:04070 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681
JBrowse link
G Cds2 CDP-diacylglycerol synthase 2 IEA KEGG rno:04070 NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
JBrowse link
G Dgka diacylglycerol kinase, alpha IEA KEGG rno:04070 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110
JBrowse link
G Dgkb diacylglycerol kinase, beta IEA KEGG rno:04070 NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043
JBrowse link
G Dgkd diacylglycerol kinase, delta IEA KEGG rno:04070 NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345
JBrowse link
G Dgkg diacylglycerol kinase, gamma IEA KEGG rno:04070 NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
JBrowse link
G Dgki diacylglycerol kinase, iota IEA KEGG rno:04070 NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733
JBrowse link
G Dgkq diacylglycerol kinase, theta IEA KEGG rno:04070 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131
JBrowse link
G Dgkz diacylglycerol kinase zeta IEA KEGG rno:04070 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Impa1 inositol monophosphatase 1 IEA KEGG rno:04070 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Impa2 inositol monophosphatase 2 IEA KEGG rno:04070 NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641
JBrowse link
G Inpp1 inositol polyphosphate-1-phosphatase IEA KEGG rno:04070 NCBI chr 9:48,688,037...48,717,793
Ensembl chr 9:48,669,901...48,717,793
JBrowse link
G Inpp4a inositol polyphosphate-4-phosphatase type I A IEA KEGG rno:04070 NCBI chr 9:39,528,245...39,650,574
Ensembl chr 9:39,528,674...39,646,581
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B IEA KEGG rno:04070 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A IEA KEGG rno:04070 NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428
JBrowse link
G Inpp5b inositol polyphosphate-5-phosphatase B IEA KEGG rno:04070 NCBI chr 5:136,996,766...137,061,315
Ensembl chr 5:136,996,686...137,061,315
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IEA KEGG rno:04070 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J IEA KEGG rno:04070 NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326
JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K IEA KEGG rno:04070 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IEA KEGG rno:04070 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase IEA KEGG rno:04070 NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase IEA KEGG rno:04070 NCBI chr 6:121,710,750...121,844,501
Ensembl chr 6:121,710,755...121,844,107
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A IEA KEGG rno:04070 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B IEA KEGG rno:04070 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IEA KEGG rno:04070 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 IEA KEGG rno:04070 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 IEA KEGG rno:04070 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
JBrowse link
G Ocrl OCRL, inositol polyphosphate-5-phosphatase IEA KEGG rno:04070 NCBI chr  X:127,089,508...127,140,362
Ensembl chr  X:127,089,590...127,140,362
JBrowse link
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha IEA KEGG rno:04070 NCBI chr 1:240,902,804...240,929,234
Ensembl chr 1:240,902,855...240,929,337
JBrowse link
G Pi4k2b phosphatidylinositol 4-kinase type 2 beta IEA KEGG rno:04070 NCBI chr14:58,221,790...58,248,716
Ensembl chr14:58,220,437...58,248,673
JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha IEA KEGG rno:04070 NCBI chr11:83,609,136...83,726,876
Ensembl chr11:83,609,069...83,724,080
JBrowse link
G Pi4kb phosphatidylinositol 4-kinase beta IEA KEGG rno:04070 NCBI chr 2:182,540,377...182,572,684
Ensembl chr 2:182,540,567...182,588,488
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha IEA KEGG rno:04070 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta IEA KEGG rno:04070 NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612
JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma IEA KEGG rno:04070 NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 IEA KEGG rno:04070 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha IEA KEGG rno:04070 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta IEA KEGG rno:04070 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta IEA KEGG rno:04070 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA KEGG rno:04070 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG rno:04070 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG rno:04070 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 IEA KEGG rno:04070 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing IEA KEGG rno:04070 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha IEA KEGG rno:04070 NCBI chr17:81,496,669...81,668,180 JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta IEA KEGG rno:04070 NCBI chr10:82,706,016...82,734,938
Ensembl chr10:82,701,098...82,734,938
JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase type 2 gamma IEA KEGG rno:04070 NCBI chr 7:63,020,004...63,035,086
Ensembl chr 7:63,020,000...63,035,078
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha IEA KEGG rno:04070 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta IEA KEGG rno:04070 NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672
JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma IEA KEGG rno:04070 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988
JBrowse link
G Plcb1 phospholipase C beta 1 IEA KEGG rno:04070 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plcb2 phospholipase C, beta 2 IEA KEGG rno:04070 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302
JBrowse link
G Plcb3 phospholipase C beta 3 IEA KEGG rno:04070 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
JBrowse link
G Plcb4 phospholipase C, beta 4 IEA KEGG rno:04070 NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
JBrowse link
G Plcd1 phospholipase C, delta 1 IEA KEGG rno:04070 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186
JBrowse link
G Plcd3 phospholipase C, delta 3 IEA KEGG rno:04070 NCBI chr10:88,026,707...88,048,080
Ensembl chr10:88,026,740...88,048,296
JBrowse link
G Plcd4 phospholipase C, delta 4 IEA KEGG rno:04070 NCBI chr 9:76,115,523...76,158,602
Ensembl chr 9:76,117,168...76,142,453
JBrowse link
G Plce1 phospholipase C, epsilon 1 IEA KEGG rno:04070 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
JBrowse link
G Plcg1 phospholipase C, gamma 1 IEA KEGG rno:04070 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plcg2 phospholipase C, gamma 2 IEA KEGG rno:04070 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Plcz1 phospholipase C, zeta 1 IEA KEGG rno:04070 NCBI chr 4:172,873,110...172,929,191
Ensembl chr 4:172,873,112...172,928,358
JBrowse link
G Prkca protein kinase C, alpha IEA KEGG rno:04070 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcb protein kinase C, beta IEA KEGG rno:04070 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcg protein kinase C, gamma IEA KEGG rno:04070 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Pten phosphatase and tensin homolog IEA KEGG rno:04070 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Sec16a SEC16 homolog A, endoplasmic reticulum export factor IEA KEGG rno:04070 NCBI chr 3:9,229,687...9,264,837
Ensembl chr 3:9,229,687...9,264,273
JBrowse link
G Synj1 synaptojanin 1 IEA KEGG rno:04070 NCBI chr11:30,192,629...30,269,277
Ensembl chr11:30,192,629...30,269,220
JBrowse link
G Synj2 synaptojanin 2 IEA KEGG rno:04070 NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687
JBrowse link
phosphatidylinositol 3-kinase-Akt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO PID
RGD
PMID:17641274 PMID:12084817 PID:200197, RGD:2290458, RGD:625444 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IMP
ISO
PID
RGD
PMID:12089343 PMID:17641274 PID:200197, RGD:632179, RGD:2290458 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 ISO PID
RGD
PMID:17641274 PID:200197, RGD:2290458 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Bad BCL2-associated agonist of cell death ISO PID PID:200197 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Casp9 caspase 9 ISO PID PID:200197 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO PID PID:200197 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO PID PID:200197 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO PID PID:200197 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Foxo1 forkhead box O1 ISO PID PID:200197 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Foxo3 forkhead box O3 ISO PID PID:200197 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxo4 forkhead box O4 ISO PID PID:200197 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO PID PID:200197 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO PID PID:200197 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO PID PID:200197 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO RGD PMID:17371235 RGD:2302068 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 ISO RGD PMID:17371235 RGD:2302068 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Insr insulin receptor IEP RGD PMID:29896241 PMID:25352008 RGD:14700925, RGD:14700927 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Kpna1 karyopherin subunit alpha 1 ISO PID PID:200197 NCBI chr11:64,715,844...64,774,647
Ensembl chr11:64,717,563...64,774,623
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO PID PID:200197 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapkap1 MAPK associated protein 1 ISO PID PID:200197 NCBI chr 3:17,715,813...17,918,387
Ensembl chr 3:17,715,834...17,918,384
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog ISO PID PID:200197 NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO PID PID:200197 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO PID
RGD
PMID:17641274 PID:200197, RGD:2290458 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 ISO RGD PMID:24794538 RGD:11535053 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
JBrowse link
G Phlpp2 PH domain and leucine rich repeat protein phosphatase 2 ISO RGD PMID:24794538 RGD:11535053 NCBI chr19:37,835,125...37,901,804
Ensembl chr19:37,835,125...37,905,513
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO RGD PMID:17641274 RGD:2290458 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta ISO RGD PMID:17641274 RGD:2290458 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta ISO RGD PMID:17641274 PMID:26311905 PMID:29893841 RGD:2290458, RGD:40890274, RGD:40890270 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO
IMP
RGD PMID:29666415 PMID:29323718 PMID:21665152 RGD:38599151, RGD:38599216, RGD:38599159 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:17641274 RGD:2290458 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 ISO RGD PMID:17641274 RGD:2290458 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 ISO RGD PMID:17641274 RGD:2290458 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:23454242 RGD:11535052 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta ISO RGD PMID:23454242 RGD:11535052 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha ISO RGD PMID:23454242 RGD:11535052 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta ISO RGD PMID:23454242 RGD:11535052 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha ISO RGD PMID:23454242 RGD:11535052 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO PID PID:200197 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO PID PID:200197 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Pten phosphatase and tensin homolog ISO RGD PMID:17641274 RGD:2290458 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO PID PID:200197 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO PID PID:200197 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Sfn stratifin ISO PID PID:200197 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO PID PID:200197 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200197 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tbc1d4 TBC1 domain family, member 4 ISO PID PID:200197 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta ISO PID PID:200197 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon ISO PID PID:200197 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma ISO PID PID:200197 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta ISO PID PID:200197 NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta ISO PID PID:200197 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta ISO PID PID:200197 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
protein kinase A (PKA) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 ISO RGD PMID:18948702 RGD:2312469 NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969
JBrowse link
G Adcy10 adenylate cyclase 10 ISO RGD PMID:18948702 RGD:2312469 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951
JBrowse link
G Adcy2 adenylate cyclase 2 ISO RGD PMID:18948702 RGD:2312469 NCBI chr 1:34,375,639...34,822,237
Ensembl chr 1:34,375,895...34,822,236
JBrowse link
G Adcy3 adenylate cyclase 3 ISO RGD PMID:18948702 RGD:2312469 NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686
JBrowse link
G Adcy4 adenylate cyclase 4 ISO RGD PMID:18948702 RGD:2312469 NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108
JBrowse link
G Adcy5 adenylate cyclase 5 ISO RGD PMID:18948702 RGD:2312469 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcy6 adenylate cyclase 6 ISO
IDA
RGD PMID:18948702 PMID:15579502 RGD:2312469, RGD:2313211 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Adcy7 adenylate cyclase 7 ISO RGD PMID:18948702 RGD:2312469 NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
JBrowse link
G Adcy8 adenylate cyclase 8 ISO RGD PMID:18948702 RGD:2312469 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911
JBrowse link
G Adcy9 adenylate cyclase 9 ISO RGD PMID:18948702 RGD:2312469 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Akap1 A-kinase anchoring protein 1 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akap10 A-kinase anchoring protein 10 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr10:46,545,464...46,608,768
Ensembl chr10:46,551,532...46,608,769
JBrowse link
G Akap11 A-kinase anchoring protein 11 ISO
IMP
RGD PMID:14715913 PMID:18385542 PMID:19319965 RGD:2312475, RGD:2312637, RGD:2312477 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605
JBrowse link
G Akap12 A-kinase anchoring protein 12 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Akap13 A-kinase anchoring protein 13 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akap14 A-kinase anchoring protein 14 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr  X:116,395,512...116,410,697
Ensembl chr  X:116,395,516...116,410,697
JBrowse link
G Akap2 A-kinase anchoring protein 2 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 5:72,536,986...72,648,524
Ensembl chr 5:72,181,718...72,648,524
JBrowse link
G Akap3 A-kinase anchoring protein 3 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 4:159,688,049...159,714,067
Ensembl chr 4:159,699,289...159,713,903
JBrowse link
G Akap4 A-kinase anchoring protein 4 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr  X:15,435,391...15,445,684
Ensembl chr  X:15,435,410...15,445,684
JBrowse link
G Akap5 A-kinase anchoring protein 5 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Akap6 A-kinase anchoring protein 6 ISO
IMP
RGD PMID:14715913 PMID:11296225 PMID:19319965 RGD:2312475, RGD:68716, RGD:2312477 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO
IMP
RGD PMID:14715913 PMID:17901878 PMID:19319965 RGD:2312475, RGD:2312630, RGD:2312477 NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797
JBrowse link
G Akap8 A-kinase anchoring protein 8 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 7:11,316,224...11,332,523
Ensembl chr 7:11,316,228...11,332,399
JBrowse link
G Akap9 A-kinase anchoring protein 9 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:15911134 RGD:5131271 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Ezr ezrin ISO RGD PMID:14715913 RGD:2312475 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Pde10a phosphodiesterase 10A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
JBrowse link
G Pde11a phosphodiesterase 11A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 3:60,913,562...61,297,154 JBrowse link
G Pde1a phosphodiesterase 1A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
JBrowse link
G Pde1b phosphodiesterase 1B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580
JBrowse link
G Pde1c phosphodiesterase 1C ISO RGD PMID:17376027 RGD:2312479 NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:85,300,858...85,863,219
JBrowse link
G Pde2a phosphodiesterase 2A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pde3a phosphodiesterase 3A ISO RGD PMID:17376027 PMID:17376027 RGD:2312479, RGD:2312479 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274
JBrowse link
G Pde3b phosphodiesterase 3B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334
JBrowse link
G Pde4a phosphodiesterase 4A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 8:19,706,649...19,751,937
Ensembl chr 8:19,703,290...19,751,961
JBrowse link
G Pde4b phosphodiesterase 4B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pde4c phosphodiesterase 4C ISO RGD PMID:17376027 RGD:2312479 NCBI chr16:18,690,727...18,711,555
Ensembl chr16:18,691,700...18,710,640
JBrowse link
G Pde4d phosphodiesterase 4D ISO
IMP
RGD PMID:17376027 PMID:11296225 RGD:2312479, RGD:68716 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pde7a phosphodiesterase 7A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 2:101,714,767...101,806,853
Ensembl chr 2:101,718,444...101,806,681
JBrowse link
G Pde7b phosphodiesterase 7B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:15,174,001...15,493,267
Ensembl chr 1:15,182,704...15,492,900
JBrowse link
G Pde8a phosphodiesterase 8A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024
JBrowse link
G Pde8b phosphodiesterase 8B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:14715913 RGD:2312475 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:14715913 RGD:2312475 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha ISO RGD PMID:14715913 RGD:2312475 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta ISO RGD PMID:14715913 RGD:2312475 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha ISO RGD PMID:14715913 RGD:2312475 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta ISO RGD PMID:14715913 RGD:2312475 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
JBrowse link
protein kinase C (PKC) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:15380937 RGD:5131492 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone ISO RGD PMID:19934406 RGD:5131489 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Copb1 COPI coat complex subunit beta 1 ISO RGD PMID:18491053 RGD:5131491 NCBI chr 1:168,404,334...168,438,589
Ensembl chr 1:168,404,335...168,438,416
JBrowse link
G Fscn1 fascin actin-bundling protein 1 ISO RGD PMID:15380937 RGD:5131492 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:15380937 RGD:5131492 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:19934406 RGD:5131489 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase ISO RGD PMID:15380937 RGD:5131492 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Ldb3 LIM domain binding 3 ISO RGD PMID:18491053 PMID:15380937 RGD:5131491, RGD:5131492 NCBI chr16:9,855,768...9,920,108
Ensembl chr16:9,855,927...9,918,532
JBrowse link
G Pard3 par-3 family cell polarity regulator ISO RGD PMID:16525119 RGD:5132275 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha ISO RGD PMID:16525119 RGD:5132275 NCBI chr19:33,589,583...33,591,900
Ensembl chr19:33,589,542...33,591,900
JBrowse link
G Pard6b par-6 family cell polarity regulator beta ISO RGD PMID:16525119 RGD:5132275 NCBI chr 3:156,790,540...156,811,620
Ensembl chr 3:156,790,540...156,811,622
JBrowse link
G Pard6g par-6 family cell polarity regulator gamma ISO RGD PMID:16525119 RGD:5132275 NCBI chr18:73,498,119...73,565,048
Ensembl chr18:73,498,021...73,565,029
JBrowse link
G Pcnt pericentrin ISO RGD PMID:15380937 RGD:5131492 NCBI chr20:12,190,597...12,278,723
Ensembl chr20:12,191,648...12,278,710
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO RGD PMID:19934406 RGD:5131489 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 IMP
ISO
RGD PMID:20819118 PMID:18511290 RGD:8693633, RGD:5131497 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
JBrowse link
G Phlpp2 PH domain and leucine rich repeat protein phosphatase 2 ISO RGD PMID:18511290 RGD:5131497 NCBI chr19:37,835,125...37,901,804
Ensembl chr19:37,835,125...37,905,513
JBrowse link
G Pick1 protein interacting with PRKCA 1 ISO RGD PMID:18491053 RGD:5131491 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link
G Plcb1 phospholipase C beta 1 ISO RGD PMID:17524618 RGD:5131502 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plcb2 phospholipase C, beta 2 ISO RGD PMID:17524618 RGD:5131502 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302
JBrowse link
G Plcb3 phospholipase C beta 3 ISO RGD PMID:17524618 RGD:5131502 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
JBrowse link
G Plcb4 phospholipase C, beta 4 ISO RGD PMID:17524618 RGD:5131502 NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
JBrowse link
G Prkca protein kinase C, alpha ISO RGD PMID:19934406 RGD:5131489 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcb protein kinase C, beta ISO RGD PMID:19934406 RGD:5131489 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcd protein kinase C, delta ISO RGD PMID:19934406 RGD:5131489 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon ISO RGD PMID:19934406 RGD:5131489 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcg protein kinase C, gamma ISO RGD PMID:19934406 RGD:5131489 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Prkch protein kinase C, eta ISO
IMP
RGD PMID:19934406 PMID:9677361 RGD:5131489, RGD:5131657 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Prkci protein kinase C, iota ISO RGD PMID:19934406 PMID:16525119 RGD:5131489, RGD:5132275 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
JBrowse link
G Prkcq protein kinase C, theta ISO RGD PMID:19934406 RGD:5131489 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Prkcz protein kinase C, zeta ISO
IMP
RGD PMID:19934406 PMID:16525119 PMID:20570724 RGD:5131489, RGD:5132275, RGD:5131661 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Rack1 receptor for activated C kinase 1 ISO RGD PMID:18491053 RGD:5131491 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Rasa1 RAS p21 protein activator 1 IMP RGD PMID:7588705 RGD:10002727 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
sphingosine 1-phosphate signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 ISO PID PID:200085 PID:200123 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO PID PID:200046 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt3 AKT serine/threonine kinase 3 ISO PID PID:200046 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Cdc42 cell division cycle 42 ISO PID PID:200054 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdh5 cadherin 5 ISO PID PID:200211 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO PID PID:200046 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Elk1 ETS transcription factor ELK1 ISO PID PID:200211 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO PID PID:200046 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200211 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gna11 G protein subunit alpha 11 ISO PID PID:200046 PID:200123 PID:200211 NCBI chr 7:8,163,752...8,177,636
Ensembl chr 7:8,162,750...8,179,812
JBrowse link
G Gna12 G protein subunit alpha 12 ISO PID PID:200046 PID:200054 PID:200076 PID:200123 PID:200211 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255
JBrowse link
G Gna13 G protein subunit alpha 13 ISO PID PID:200046 PID:200054 PID:200123 PID:200211 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774
JBrowse link
G Gna14 G protein subunit alpha 14 ISO PID PID:200046 PID:200123 PID:200211 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423
JBrowse link
G Gna15 G protein subunit alpha 15 ISO PID PID:200046 PID:200123 PID:200211 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Gnai1 G protein subunit alpha i1 ISO PID PID:200046 PID:200054 PID:200076 PID:200085 PID:200123 PID:200211 NCBI chr 4:16,813,941...16,898,111
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Gnai2 G protein subunit alpha i2 ISO PID PID:200046 PID:200054 PID:200076 PID:200085 PID:200123 PID:200211 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnai3 G protein subunit alpha i3 ISO PID PID:200046 PID:200054 PID:200076 PID:200085 PID:200123 PID:200211 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gnao1 G protein subunit alpha o1 ISO PID PID:200046 PID:200054 PID:200076 PID:200085 PID:200123 PID:200211 NCBI chr19:11,034,874...11,192,502
Ensembl chr19:11,035,956...11,192,493
JBrowse link
G Gnaq G protein subunit alpha q ISO PID PID:200046 PID:200123 PID:200211 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Gnaz G protein subunit alpha z ISO PID PID:200046 PID:200054 PID:200076 PID:200085 PID:200123 PID:200211 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907
JBrowse link
G Irs1 insulin receptor substrate 1 ISO PID PID:200211 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itgav integrin subunit alpha V ISO PID PID:200046 PID:200085 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb3 integrin subunit beta 3 ISO PID PID:200046 PID:200085 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jak2 Janus kinase 2 ISO PID PID:200046 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200211 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kdr kinase insert domain receptor ISO PID PID:200085 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO PID PID:200046 PID:200054 PID:200085 PID:200211 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO PID PID:200211 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO PID PID:200046 PID:200054 PID:200085 PID:200211 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO PID PID:200211 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 ISO PID PID:200211 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO PID PID:200046 PID:200085 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO PID PID:200046 PID:200085 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Plcb2 phospholipase C, beta 2 ISO PID PID:200085 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302
JBrowse link
G Plcg1 phospholipase C, gamma 1 ISO PID PID:200054 PID:200085 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO PID PID:200085 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rac1 Rac family small GTPase 1 ISO PID PID:200046 PID:200085 PID:200211 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rhoa ras homolog family member A ISO PID PID:200046 PID:200054 PID:200076 PID:200085 PID:200211 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 ISO PID PID:200046 PID:200085 PID:200123 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 ISO PID PID:200046 PID:200123 PID:200211 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 ISO PID PID:200046 PID:200123 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505
JBrowse link
G S1pr4 sphingosine-1-phosphate receptor 4 ISO PID PID:200054 PID:200123 NCBI chr 7:8,207,767...8,210,043
Ensembl chr 7:8,208,098...8,211,893
JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 ISO PID PID:200054 PID:200076 PID:200123 NCBI chr 8:19,786,676...19,791,862
Ensembl chr 8:19,786,663...19,791,795
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 ISO PID PID:200123 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 ISO PID PID:200123 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534
JBrowse link
G Sphk1 sphingosine kinase 1 ISO PID PID:200085 PID:200123 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Sphk2 sphingosine kinase 2 ISO PID PID:200123 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200046 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Vegfa vascular endothelial growth factor A ISO PID PID:200046 PID:200085 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

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