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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:cell death pathway
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Accession:PW:0000275 term browser browse the term
Definition:A cell death pathway represents the particular series of events leading to the demise of a whole cell or parts of its contents. It plays an essential role in cellular and tissue homeostasis. Biochemical and morphological characteristics are used in the classification of various forms of cell death. Deregulation of cell death can contribute to the development of cancer and neurodegeneration.
Synonyms:related_synonym: cell death

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altered mitochondrial autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pink1 PTEN induced kinase 1 ISO RGD PMID:24735649 RGD:10450527 NCBI chrNW_004624764:5,656,207...5,671,260
Ensembl chrNW_004624764:5,656,229...5,671,260 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24735649 RGD:10450527 NCBI chrNW_004624855:430,148...1,992,121
Ensembl chrNW_004624855:430,260...1,989,747 		JBrowse link
apoptotic cell death pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfn2 mitofusin 2 ISO RGD PMID:26485208 RGD:12910856 NCBI chrNW_004624818:1,041,371...1,065,061
Ensembl chrNW_004624818:1,041,369...1,065,023 		JBrowse link
G Snca synuclein alpha ISO RGD PMID:16837598 RGD:13506279 NCBI chrNW_004624757:17,393,046...17,528,783
Ensembl chrNW_004624757:17,392,998...17,528,320 		JBrowse link
autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp2 acid phosphatase 2, lysosomal ISO RGD PMID:18690537 RGD:4892631 NCBI chrNW_004624767:1,473,186...1,481,395
Ensembl chrNW_004624767:1,473,205...1,485,345 		JBrowse link
G Atg10 autophagy related 10 ISO RGD PMID:15325588 PMID:20034776 RGD:1643329 RGD:4889529 NCBI chrNW_004624743:2,381,131...2,663,640
Ensembl chrNW_004624743:2,381,038...2,649,322 		JBrowse link
G Atg12 autophagy related 12 ISO RGD PMID:15325588 PMID:18059433 PMID:20034776 RGD:1643329 RGD:2301217 RGD:4889529 NCBI chrNW_004624733:6,046,073...6,056,321
Ensembl chrNW_004624733:6,045,432...6,060,784 		JBrowse link
G Atg13 autophagy related 13 ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624767:1,924,672...1,953,868 JBrowse link
G Atg14 autophagy related 14 ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624884:165,443...220,525 JBrowse link
G Atg16l1 autophagy related 16 like 1 ISO RGD PMID:15325588 PMID:20034776 RGD:1643329 RGD:4889529 NCBI chrNW_004624843:5,797,725...5,838,768
Ensembl chrNW_004624843:5,805,069...5,838,741 		JBrowse link
G Atg16l2 autophagy related 16 like 2 ISO RGD PMID:15325588 PMID:20034776 RGD:1643329 RGD:4889529 NCBI chrNW_004624817:4,123,963...4,153,720
Ensembl chrNW_004624817:4,140,543...4,147,597 		JBrowse link
G Atg3 autophagy related 3 ISO RGD PMID:15325588 PMID:17110912 PMID:20034776 RGD:1643237 RGD:1643329 RGD:4889529 NCBI chrNW_004624731:35,978,595...36,004,900 JBrowse link
G Atg4a autophagy related 4A cysteine peptidase ISO RGD PMID:15325588 RGD:1643329 NCBI chrNW_004624803:8,336,123...8,407,354
Ensembl chrNW_004624803:8,337,042...8,407,222 		JBrowse link
G Atg4b autophagy related 4B cysteine peptidase ISO RGD PMID:15325588 RGD:1643329 NCBI chrNW_004624847:5,605,818...5,629,729
Ensembl chrNW_004624847:5,605,844...5,629,891 		JBrowse link
G Atg4c autophagy related 4C cysteine peptidase ISO RGD PMID:15325588 RGD:1643329 NCBI chrNW_004624742:31,061,869...31,130,786
Ensembl chrNW_004624742:31,060,376...31,127,740 		JBrowse link
G Atg4d autophagy related 4D cysteine peptidase ISO RGD PMID:15325588 RGD:1643329 NCBI chrNW_004624828:2,617,853...2,624,756
Ensembl chrNW_004624828:2,617,773...2,624,756 		JBrowse link
G Atg5 autophagy related 5 ISO RGD PMID:18059433 PMID:20034776 RGD:2301217 RGD:4889529 NCBI chrNW_004624780:15,987,483...16,124,158
Ensembl chrNW_004624780:15,987,397...16,124,151 		JBrowse link
G Atg7 autophagy related 7 ISO RGD PMID:15325588 PMID:17665967 PMID:20034776 RGD:1643198 RGD:1643329 RGD:4889529 NCBI chrNW_004624943:231,978...480,933
Ensembl chrNW_004624943:232,618...481,290 		JBrowse link
G Atg9a autophagy related 9A ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624823:5,787,525...5,797,536
Ensembl chrNW_004624823:5,787,601...5,797,534 		JBrowse link
G Atg9b autophagy related 9B ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624800:5,589,366...5,600,253
Ensembl chrNW_004624800:5,591,297...5,598,739 		JBrowse link
G Becn1 beclin 1 ISO RGD PMID:15325588 PMID:16697404 PMID:20034776 RGD:1643194 RGD:1643329 RGD:4889529 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Chmp2b charged multivesicular body protein 2B ISO RGD PMID:19535733 RGD:4892619 NCBI chrNW_004624789:3,557,811...3,587,814
Ensembl chrNW_004624789:3,557,797...3,587,703 		JBrowse link
G Chmp3 charged multivesicular body protein 3 ISO RGD PMID:19535733 RGD:4892619 NCBI chrNW_004624749:16,738,538...16,772,553
Ensembl chrNW_004624749:16,738,416...16,772,391 		JBrowse link
G Gabarap GABA type A receptor-associated protein ISO RGD PMID:15325588 PMID:20562859 RGD:1643329 RGD:4890444 NCBI chrNW_004624786:9,857,370...9,859,675
Ensembl chrNW_004624786:9,857,370...9,860,063 		JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 ISO RGD PMID:20562859 RGD:4890444 NCBI chrNW_004624752:26,971,266...26,979,483
Ensembl chrNW_004624752:26,971,187...26,981,929 		JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 ISO RGD PMID:15325588 PMID:20562859 RGD:1643329 RGD:4890444 NCBI chrNW_004624746:11,393,439...11,405,152
Ensembl chrNW_004624746:11,393,439...11,405,126 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate ISO RGD PMID:19535733 RGD:4892619 NCBI chrNW_004624801:10,620,717...10,634,670
Ensembl chrNW_004624801:10,620,753...10,634,341 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 ISO RGD PMID:18690537 PMID:20548331 RGD:4892310 RGD:4892631 NCBI chrNW_004624793:661,322...675,603
Ensembl chrNW_004624793:661,342...675,675 		JBrowse link
G Lamp2 lysosomal associated membrane protein 2 ISO RGD PMID:20548331 RGD:4892310 NCBI chrNW_004624931:297,864...343,314
Ensembl chrNW_004624931:298,328...343,915 		JBrowse link
G Map1lc3a microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:15325588 PMID:17665967 PMID:20562859 RGD:1643198 RGD:1643329 RGD:4890444 NCBI chrNW_004624842:4,800,533...4,802,235
Ensembl chrNW_004624842:4,800,539...4,802,094 		JBrowse link
G Map1lc3b microtubule associated protein 1 light chain 3 beta ISO RGD PMID:15325588 PMID:20562859 RGD:1643329 RGD:4890444 NCBI chrNW_004624746:3,084,418...3,094,250
Ensembl chrNW_004624746:3,084,392...3,094,250 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624779:16,307,875...16,435,567
Ensembl chrNW_004624779:16,307,800...16,434,169 		JBrowse link
G Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624730:6,642,195...6,744,480
Ensembl chrNW_004624730:6,642,190...6,744,470 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family ISO RGD PMID:20548331 RGD:4892310 NCBI chrNW_004624781:6,699,926...6,718,020
Ensembl chrNW_004624781:6,699,926...6,718,545 		JBrowse link
G Rab33b RAB33B, member RAS oncogene family ISO RGD PMID:20548331 RGD:4892310 NCBI chrNW_004624777:19,730,784...19,744,423
Ensembl chrNW_004624777:19,730,768...19,747,292 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family ISO RGD PMID:20548331 RGD:4892310 NCBI chrNW_004624821:5,271,246...5,311,469 JBrowse link
G Rab7a RAB7A, member RAS oncogene family ISO RGD PMID:20548331 RGD:4892310 NCBI chrNW_004625042:56,509...112,519
Ensembl chrNW_004625042:56,517...112,612 		JBrowse link
G Rb1cc1 RB1 inducible coiled-coil 1 ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624735:2,778,191...2,860,762 JBrowse link
G Rubcn rubicon autophagy regulator ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624730:61,040,848...61,111,998
Ensembl chrNW_004624730:61,040,857...61,112,926 		JBrowse link
G Snf8 SNF8 subunit of ESCRT-II ISO RGD PMID:19535733 RGD:4892619 NCBI chrNW_004624795:5,318,803...5,328,542
Ensembl chrNW_004624795:5,318,802...5,328,768 		JBrowse link
G Tsg101 tumor susceptibility 101 ISO RGD PMID:19535733 RGD:4892619 NCBI chrNW_004624766:9,932,190...9,977,725
Ensembl chrNW_004624766:9,934,228...9,977,697 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 ISO RGD PMID:15325588 PMID:20034776 RGD:1643329 RGD:4889529 NCBI chrNW_004624747:27,680,994...27,697,342
Ensembl chrNW_004624747:27,681,033...27,695,966 		JBrowse link
G Uvrag UV radiation resistance associated ISO RGD PMID:20034776 RGD:4889529 NCBI chrNW_004624817:989,362...1,371,096 JBrowse link
G Vamp3 vesicle associated membrane protein 3 ISO RGD PMID:20548331 RGD:4892310 NCBI chrNW_004624818:4,010,130...4,019,695
Ensembl chrNW_004624818:4,009,991...4,019,728 		JBrowse link
G Vamp7 vesicle associated membrane protein 7 ISO RGD PMID:20548331 RGD:4892310 NCBI chrNW_004624980:40,937...94,547
Ensembl chrNW_004624980:40,843...94,528 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A ISO RGD PMID:19535733 RGD:4892619 NCBI chrNW_004624746:17,044,173...17,059,295
Ensembl chrNW_004624746:17,047,519...17,054,738 		JBrowse link
chaperone mediated autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag1 BAG cochaperone 1 ISO RGD PMID:25724482 RGD:10755685 NCBI chrNW_004624736:38,015,150...38,025,079
Ensembl chrNW_004624736:38,015,044...38,025,079 		JBrowse link
G Ctsb cathepsin B ISO RGD PMID:24323530 RGD:10755730 NCBI chrNW_004624758:25,366,120...25,384,554
Ensembl chrNW_004624758:25,366,840...25,373,954 		JBrowse link
G Ctsd cathepsin D ISO RGD PMID:24323530 PMID:25766616 RGD:10755729 RGD:10755730 NCBI chrNW_004624767:14,661,058...14,671,116
Ensembl chrNW_004624767:14,660,936...14,671,671 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 ISO RGD PMID:25724482 RGD:10755685 NCBI chrNW_004624901:1,631,789...1,643,026
Ensembl chrNW_004624901:1,631,275...1,652,488 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:24281265 PMID:25724482 RGD:10755322 RGD:10755685 NCBI chrNW_004624819:732,118...735,391
Ensembl chrNW_004624819:732,268...735,313 		JBrowse link
G Gfap glial fibrillary acidic protein ISO RGD PMID:24281265 PMID:25724482 RGD:10755322 RGD:10755685 NCBI chrNW_004624795:395,298...400,781
Ensembl chrNW_004624795:394,436...401,231 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:25724482 RGD:10755685 NCBI chrNW_004624734:2,233,932...2,239,687
Ensembl chrNW_004624734:2,233,547...2,241,436 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:24281265 PMID:25724482 RGD:10755322 RGD:10755685 NCBI chrNW_004624880:2,070,410...2,075,069
Ensembl chrNW_004624880:2,070,523...2,079,421 		JBrowse link
G Lamp2 lysosomal associated membrane protein 2 ISO RGD PMID:24281265 PMID:25724482 RGD:10755322 RGD:10755685 NCBI chrNW_004624931:297,864...343,314
Ensembl chrNW_004624931:298,328...343,915 		JBrowse link
G St13 ST13 Hsp70 interacting protein ISO RGD PMID:25724482 RGD:10755685 NCBI chrNW_004624752:7,634,910...7,663,135
Ensembl chrNW_004624752:7,634,970...7,661,974 		JBrowse link
G Stip1 stress induced phosphoprotein 1 ISO RGD PMID:25724482 RGD:10755685 NCBI chrNW_004624767:22,102,696...22,117,809
Ensembl chrNW_004624767:22,102,477...22,118,313 		JBrowse link
extrinsic apoptotic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp10 caspase 10 ISO RGD PMID:17082813 RGD:2314187 NCBI chrNW_004624889:31,132...63,774 JBrowse link
G Casp7 caspase 7 ISO RGD PMID:17082813 RGD:2314187 NCBI chrNW_004624737:32,853,354...32,888,881
Ensembl chrNW_004624737:32,852,835...32,887,069 		JBrowse link
G Casp8 caspase 8 ISO RGD PMID:17082813 RGD:2314187 NCBI chrNW_004624899:427,064...450,931
Ensembl chrNW_004624899:424,363...451,087 		JBrowse link
G Fas Fas cell surface death receptor ISO germ cells RGD PMID:17195944 RGD:1626509 NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848 		JBrowse link
G Faslg Fas ligand ISO RGD PMID:16154149 RGD:1582433 NCBI chrNW_004624771:9,031,978...9,038,760
Ensembl chrNW_004624771:9,032,016...9,038,825 		JBrowse link
FasL mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO PID PID:200080 NCBI chrNW_004624734:507,880...525,295
Ensembl chrNW_004624734:509,368...525,295 		JBrowse link
G Bid BH3 interacting domain death agonist ISO RGD
PID		 PMID:18090083 PMID:19239902 PID:200080 RGD:2314002 RGD:4143196 NCBI chrNW_004624735:9,557,732...9,590,862
Ensembl chrNW_004624735:9,579,979...9,589,260 		JBrowse link
G Birc2 baculoviral IAP repeat containing 2 ISO PID PID:200080 NCBI chrNW_004624878:476,460...514,637 JBrowse link
G Birc3 baculoviral IAP repeat containing 3 ISO PID PID:200080 NCBI chrNW_004624878:516,750...541,475
Ensembl chrNW_004624878:523,300...536,062 		JBrowse link
G Btk Bruton tyrosine kinase ISO PID PID:200080 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171 		JBrowse link
G Casp10 caspase 10 ISO PID PID:200080 NCBI chrNW_004624889:31,132...63,774 JBrowse link
G Casp7 caspase 7 ISO RGD PMID:19239902 RGD:4143196 NCBI chrNW_004624737:32,853,354...32,888,881
Ensembl chrNW_004624737:32,852,835...32,887,069 		JBrowse link
G Casp8 caspase 8 ISO RGD
PID		 PMID:18090083 PMID:19239902 PID:200080 RGD:2314002 RGD:4143196 NCBI chrNW_004624899:427,064...450,931
Ensembl chrNW_004624899:424,363...451,087 		JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator ISO RGD
PID		 PMID:19107989 PMID:19239902 PID:200080 RGD:4143196 RGD:8662854 NCBI chrNW_004624889:76,760...108,619
Ensembl chrNW_004624889:75,396...100,989 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO PID PID:200080 NCBI chrNW_004624737:12,022,081...12,052,128
Ensembl chrNW_004624737:12,022,419...12,052,131 		JBrowse link
G Cltc clathrin heavy chain ISO PID PID:200080 NCBI chrNW_004624871:1,439,975...1,507,514
Ensembl chrNW_004624871:1,439,838...1,510,911 		JBrowse link
G Ezr ezrin ISO PID PID:200080 NCBI chrNW_004624929:827,275...873,743
Ensembl chrNW_004624929:826,531...873,572 		JBrowse link
G Fadd Fas associated via death domain ISO RGD
PID		 PMID:19239902 PID:200080 RGD:4143196 NCBI chrNW_004624767:17,050,929...17,059,648
Ensembl chrNW_004624767:17,055,509...17,059,705 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 ISO PID PID:200080 NCBI chrNW_004624816:2,386,995...2,418,312
Ensembl chrNW_004624816:2,386,647...2,420,274 		JBrowse link
G Fas Fas cell surface death receptor ISO PID
RGD		 PMID:18090083 PMID:19107989 PMID:19239902 PID:200080 RGD:2314002 RGD:4143196 RGD:8662854 NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848 		JBrowse link
G Faslg Fas ligand ISO PID
RGD		 PMID:18090083 PMID:19239902 PID:200080 RGD:2314002 RGD:4143196 NCBI chrNW_004624771:9,031,978...9,038,760
Ensembl chrNW_004624771:9,032,016...9,038,825 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta ISO PID PID:200080 NCBI chrNW_004624780:922,524...978,687
Ensembl chrNW_004624780:923,744...970,519 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO PID PID:200080 NCBI chrNW_004624946:997,571...1,015,748
Ensembl chrNW_004624946:996,814...1,013,379 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO PID PID:200080 NCBI chrNW_004624870:4,224,108...4,420,217
Ensembl chrNW_004624870:4,287,835...4,416,559 		JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 ISO PID PID:200080 NCBI chrNW_004624828:869,424...878,358
Ensembl chrNW_004624828:869,425...878,231 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200080 NCBI chrNW_004624759:2,360,655...2,429,189
Ensembl chrNW_004624759:2,363,076...2,428,273 		JBrowse link
G Mapk10 mitogen-activated protein kinase 10 ISO PID PID:200080 NCBI chrNW_004624872:2,460,308...2,830,569
Ensembl chrNW_004624872:2,461,362...2,825,161 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO PID PID:200080 NCBI chrNW_004624752:502,411...508,452
Ensembl chrNW_004624752:502,350...508,449 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 ISO PID PID:200080 NCBI chrNW_004624754:21,528,121...21,598,064
Ensembl chrNW_004624754:21,527,333...21,597,733 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO PID PID:200080 NCBI chrNW_004624928:1,442,216...1,494,275
Ensembl chrNW_004624928:1,439,146...1,494,266 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO PID PID:200080 NCBI chrNW_004624733:42,998,948...43,048,392
Ensembl chrNW_004624733:42,999,339...43,048,285 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO PID PID:200080 NCBI chrNW_004624824:279,893...383,220
Ensembl chrNW_004624824:293,374...383,156 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200080 NCBI chrNW_004624730:56,895,065...56,970,563
Ensembl chrNW_004624730:56,938,215...56,966,137 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO PID PID:200080 NCBI chrNW_004624730:15,226,786...15,399,097
Ensembl chrNW_004624730:15,226,379...15,355,857 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO PID PID:200080 NCBI chrNW_004624818:2,751,724...2,789,145
Ensembl chrNW_004624818:2,751,724...2,779,999 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200080 NCBI chrNW_004624815:1,290,106...1,376,961
Ensembl chrNW_004624815:1,289,997...1,369,610 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 ISO PID PID:200080 NCBI chrNW_004624908:1,513,916...1,523,723
Ensembl chrNW_004624908:1,513,969...1,523,295 		JBrowse link
G Rfc1 replication factor C subunit 1 ISO PID PID:200080 NCBI chrNW_004624870:4,901,963...4,985,633
Ensembl chrNW_004624870:4,901,895...4,985,654 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO PID PID:200080 NCBI chrNW_004624756:21,806,570...21,837,351
Ensembl chrNW_004624756:21,805,599...21,830,699 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 ISO PID PID:200080 NCBI chrNW_004624817:7,909,777...7,913,419
Ensembl chrNW_004624817:7,909,468...7,913,417 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200080 NCBI chrNW_004624842:2,212,561...2,260,514
Ensembl chrNW_004624842:2,211,020...2,230,132 		JBrowse link
G Syk spleen associated tyrosine kinase ISO PID PID:200080 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391 		JBrowse link
intrinsic apoptotic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 ISO RGD PMID:18931364 RGD:2313998 NCBI chrNW_004624750:8,835,521...8,940,957
Ensembl chrNW_004624750:8,837,037...8,938,009 		JBrowse link
G Bad BCL2 associated agonist of cell death ISO RGD PMID:15632274 PMID:19641503 RGD:1579966 RGD:2314029 NCBI chrNW_004624767:22,025,721...22,037,283
Ensembl chrNW_004624767:22,026,133...22,037,277 		JBrowse link
G Bak1 BCL2 antagonist/killer 1 ISO RGD PMID:17322918 PMID:18817839 RGD:2313963 RGD:2313975 NCBI chrNW_004624754:23,297,077...23,302,366
Ensembl chrNW_004624754:23,296,800...23,301,223 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO RGD PMID:15632274 PMID:17322918 PMID:18817839 PMID:18931364 PMID:18959742 RGD:1579966 RGD:2313963 RGD:2313975 RGD:2313998 RGD:2314140 NCBI chrNW_004624832:5,050,222...5,068,565
Ensembl chrNW_004624832:5,050,222...5,055,506 		JBrowse link
G Bbc3 BCL2 binding component 3 ISO RGD PMID:19095966 PMID:19641503 RGD:2313994 RGD:2314029 NCBI chrNW_004624832:6,467,716...6,476,754
Ensembl chrNW_004624832:6,470,475...6,476,754 		JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO RGD PMID:15632274 PMID:17322918 PMID:18931364 PMID:18959742 RGD:1579966 RGD:2313975 RGD:2313998 RGD:2314140 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344 		JBrowse link
G Bcl2a1 BCL2 related protein A1 ISO RGD PMID:17322918 RGD:2313975 NCBI chrNW_004624941:907,382...932,751
Ensembl chrNW_004624941:907,119...933,356 		JBrowse link
G Bcl2l1 BCL2 like 1 ISO RGD PMID:15632274 PMID:17322918 PMID:18959742 RGD:1579966 RGD:2313975 RGD:2314140 NCBI chrNW_004624741:788,445...838,513
Ensembl chrNW_004624741:789,355...839,507 		JBrowse link
G Bcl2l10 BCL2 like 10 ISO RGD PMID:17322918 RGD:2313975 NCBI chrNW_004624731:8,399,936...8,403,904 JBrowse link
G Bcl2l11 BCL2 like 11 ISO RGD PMID:19641503 RGD:2314029 NCBI chrNW_004624749:1,033,824...1,130,099
Ensembl chrNW_004624749:1,091,096...1,125,341 		JBrowse link
G Bid BH3 interacting domain death agonist ISO RGD PMID:18090083 PMID:18931364 PMID:19641503 RGD:2313998 RGD:2314002 RGD:2314029 NCBI chrNW_004624735:9,557,732...9,590,862
Ensembl chrNW_004624735:9,579,979...9,589,260 		JBrowse link
G Bik BCL2 interacting killer ISO RGD PMID:19641503 RGD:2314029 NCBI chrNW_004624752:5,839,422...5,856,350 JBrowse link
G Bmf Bcl2 modifying factor ISO RGD PMID:19641503 RGD:2314029 NCBI chrNW_004624804:7,420,003...7,440,012
Ensembl chrNW_004624804:7,423,547...7,440,014 		JBrowse link
G Bnip1 BCL2 interacting protein 1 ISO RGD PMID:12714334 PMID:19641503 RGD:2314029 RGD:634759 NCBI chrNW_004624733:16,885,430...16,941,536
Ensembl chrNW_004624733:16,925,294...16,941,839 		JBrowse link
G Bnip3 BCL2 interacting protein 3 ISO RGD PMID:14972662 PMID:19641503 RGD:2314028 RGD:2314029 NCBI chrNW_004624737:14,848,355...14,863,731
Ensembl chrNW_004624737:14,848,350...14,862,965 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like ISO RGD PMID:19641503 RGD:2314029 NCBI chrNW_004624758:21,284,165...21,309,957
Ensembl chrNW_004624758:21,284,167...21,310,398 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK ISO RGD PMID:9356461 PMID:17322918 RGD:2313975 RGD:70678 NCBI chrNW_004624847:5,564,671...5,573,459
Ensembl chrNW_004624847:5,564,979...5,573,459 		JBrowse link
G Casp7 caspase 7 ISO RGD PMID:17082813 RGD:2314187 NCBI chrNW_004624737:32,853,354...32,888,881
Ensembl chrNW_004624737:32,852,835...32,887,069 		JBrowse link
G Casp9 caspase 9 ISO RGD PMID:17082813 PMID:17869439 PMID:18090083 PMID:18817839 PMID:18931364 RGD:2313963 RGD:2313998 RGD:2314002 RGD:2314187 RGD:2314390 NCBI chrNW_004624764:1,769,270...1,789,399
Ensembl chrNW_004624764:1,773,455...1,789,423 		JBrowse link
G Fas Fas cell surface death receptor ISO germ cells RGD PMID:17195944 RGD:1626509 NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848 		JBrowse link
G Hrk harakiri, BCL2 interacting protein ISO RGD PMID:10075695 PMID:17428807 PMID:19641503 RGD:2290488 RGD:2314029 RGD:70327 NCBI chrNW_004624747:16,365,938...16,387,841
Ensembl chrNW_004624747:16,366,080...16,387,840 		JBrowse link
G Htra2 HtrA serine peptidase 2 ISO RGD PMID:16978742 RGD:2314385 NCBI chrNW_004624749:28,980,375...28,983,719
Ensembl chrNW_004624749:28,980,362...28,983,869 		JBrowse link
G LOC101718508 cytochrome c, somatic ISO RGD PMID:18817839 PMID:18931364 RGD:2313963 RGD:2313998 NCBI chrNW_004624739:5,411,192...5,413,995
Ensembl chrNW_004624739:5,411,273...5,413,995 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member ISO RGD PMID:9356461 PMID:17322918 RGD:2313975 RGD:70678 NCBI chrNW_004624772:18,287,587...18,292,384
Ensembl chrNW_004624772:18,289,509...18,319,033 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 ISO RGD PMID:18959742 PMID:19641503 RGD:2314029 RGD:2314140 NCBI chrNW_004624792:5,330,289...5,338,067 JBrowse link
mitochondrial autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 ISO RGD PMID:23065344 RGD:10401098 NCBI chrNW_004624767:1,967,002...2,160,102
Ensembl chrNW_004624767:1,966,898...2,160,465 		JBrowse link
G Atg7 autophagy related 7 ISO RGD PMID:25840011 RGD:10400888 NCBI chrNW_004624943:231,978...480,933
Ensembl chrNW_004624943:232,618...481,290 		JBrowse link
G Atxn3 ataxin 3 ISO RGD PMID:25995186 RGD:10401790 NCBI chrNW_004624734:8,685,994...8,726,329 JBrowse link
G Becn1 beclin 1 ISO RGD PMID:23065344 RGD:10401098 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Bnip3 BCL2 interacting protein 3 ISO RGD PMID:23065344 PMID:25840011 RGD:10400888 RGD:10401098 NCBI chrNW_004624737:14,848,355...14,863,731
Ensembl chrNW_004624737:14,848,350...14,862,965 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like ISO RGD PMID:23065344 PMID:25840011 RGD:10400888 RGD:10401098 NCBI chrNW_004624758:21,284,165...21,309,957
Ensembl chrNW_004624758:21,284,167...21,310,398 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 ISO RGD PMID:25840011 RGD:10400888 NCBI chrNW_004624741:1,566,380...1,635,365 JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 ISO RGD PMID:25840011 RGD:10400888 NCBI chrNW_004624746:28,012,543...28,064,610
Ensembl chrNW_004624746:28,012,556...28,060,413 		JBrowse link
G Csnk2b casein kinase 2 beta ISO RGD PMID:25840011 RGD:10400888 NCBI chrNW_004624754:24,533,134...24,538,233 JBrowse link
G Fundc1 FUN14 domain containing 1 ISO RGD PMID:25840011 RGD:10400888 NCBI chrNW_004624887:626,321...641,296
Ensembl chrNW_004624887:626,321...641,293 		JBrowse link
G Optn optineurin ISO RGD PMID:25995186 RGD:10401790 NCBI chrNW_004624805:5,683,095...5,717,558
Ensembl chrNW_004624805:5,683,021...5,721,336 		JBrowse link
G Parl presenilin associated rhomboid like ISO RGD PMID:25526784 RGD:10402124 NCBI chrNW_004624730:72,642,828...72,683,820
Ensembl chrNW_004624730:72,642,925...72,683,820 		JBrowse link
G Pgam5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase ISO RGD PMID:25840011 RGD:10400888 NCBI chrNW_004624747:28,078,138...28,084,920
Ensembl chrNW_004624747:28,078,368...28,085,437 		JBrowse link
G Pink1 PTEN induced kinase 1 ISO RGD PMID:23065344 PMID:25840011 PMID:25995186 RGD:10400888 RGD:10401098 RGD:10401790 NCBI chrNW_004624764:5,656,207...5,671,260
Ensembl chrNW_004624764:5,656,229...5,671,260 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:23065344 PMID:25840011 PMID:25995186 RGD:10400888 RGD:10401098 RGD:10401790 NCBI chrNW_004624855:430,148...1,992,121
Ensembl chrNW_004624855:430,260...1,989,747 		JBrowse link
G Sqstm1 sequestosome 1 ISO RGD PMID:23065344 PMID:25995186 RGD:10401098 RGD:10401790 NCBI chrNW_004624733:42,689,454...42,700,916
Ensembl chrNW_004624733:42,691,841...42,700,916 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:25840011 RGD:10400888 NCBI chrNW_004624842:2,212,561...2,260,514
Ensembl chrNW_004624842:2,211,020...2,230,132 		JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 ISO RGD PMID:25526784 RGD:10402124 NCBI chrNW_004624739:7,854,226...7,863,387
Ensembl chrNW_004624739:7,853,621...7,864,757 		JBrowse link
G Ube2l3 ubiquitin conjugating enzyme E2 L3 ISO RGD PMID:25995186 RGD:10401790 NCBI chrNW_004624747:1,125,009...1,178,595
Ensembl chrNW_004624747:1,125,022...1,177,524 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 ISO RGD PMID:25840011 RGD:10400888 NCBI chrNW_004624747:27,680,994...27,697,342
Ensembl chrNW_004624747:27,681,033...27,695,966 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 ISO RGD PMID:25995186 RGD:10401790 NCBI chrNW_004624802:5,559,107...5,682,338
Ensembl chrNW_004624802:5,560,574...5,682,300 		JBrowse link
G Usp30 ubiquitin specific peptidase 30 ISO RGD PMID:25995186 RGD:10401790 NCBI chrNW_004624747:12,219,139...12,248,614
Ensembl chrNW_004624747:12,184,297...12,250,687 		JBrowse link
G Usp8 ubiquitin specific peptidase 8 ISO RGD PMID:25995186 RGD:10401790 NCBI chrNW_004624731:9,615,963...9,678,969
Ensembl chrNW_004624731:9,613,227...9,679,404 		JBrowse link
Trail mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist ISO RGD PMID:17403612 PMID:19961901 RGD:4143170 RGD:4143171 NCBI chrNW_004624735:9,557,732...9,590,862
Ensembl chrNW_004624735:9,579,979...9,589,260 		JBrowse link
G Casp10 caspase 10 ISO PID PID:200068 NCBI chrNW_004624889:31,132...63,774 JBrowse link
G Casp7 caspase 7 ISO RGD PMID:19961901 RGD:4143171 NCBI chrNW_004624737:32,853,354...32,888,881
Ensembl chrNW_004624737:32,852,835...32,887,069 		JBrowse link
G Casp8 caspase 8 ISO PID
RGD		 PMID:17403612 PMID:19961901 PID:200068 RGD:4143170 RGD:4143171 NCBI chrNW_004624899:427,064...450,931
Ensembl chrNW_004624899:424,363...451,087 		JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator ISO PID
RGD		 PMID:17403612 PMID:19961901 PID:200068 RGD:4143170 RGD:4143171 NCBI chrNW_004624889:76,760...108,619
Ensembl chrNW_004624889:75,396...100,989 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO PID PID:200068 NCBI chrNW_004624737:12,022,081...12,052,128
Ensembl chrNW_004624737:12,022,419...12,052,131 		JBrowse link
G Dap3 death associated protein 3 ISO PID PID:200068 NCBI chrNW_004624885:1,135,770...1,170,447
Ensembl chrNW_004624885:1,137,191...1,170,139 		JBrowse link
G Fadd Fas associated via death domain ISO PID
RGD		 PMID:17403612 PMID:19961901 PID:200068 RGD:4143170 RGD:4143171 NCBI chrNW_004624767:17,050,929...17,059,648
Ensembl chrNW_004624767:17,055,509...17,059,705 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta ISO PID PID:200068 NCBI chrNW_004624780:922,524...978,687
Ensembl chrNW_004624780:923,744...970,519 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO PID PID:200068 NCBI chrNW_004624946:997,571...1,015,748
Ensembl chrNW_004624946:996,814...1,013,379 		JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 ISO PID PID:200068 NCBI chrNW_004624786:14,457,382...14,597,027
Ensembl chrNW_004624786:14,457,452...14,597,027 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200068 NCBI chrNW_004624759:2,360,655...2,429,189
Ensembl chrNW_004624759:2,363,076...2,428,273 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO PID PID:200068 NCBI chrNW_004624747:1,296,062...1,389,674
Ensembl chrNW_004624747:1,296,221...1,389,757 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO PID PID:200068 NCBI chrNW_004624782:13,150,824...13,158,327
Ensembl chrNW_004624782:13,152,039...13,159,113 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO PID PID:200068 NCBI chrNW_004624928:1,442,216...1,494,275
Ensembl chrNW_004624928:1,439,146...1,494,266 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200068 NCBI chrNW_004624730:56,895,065...56,970,563
Ensembl chrNW_004624730:56,938,215...56,966,137 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO PID PID:200068 NCBI chrNW_004624730:15,226,786...15,399,097
Ensembl chrNW_004624730:15,226,379...15,355,857 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO PID PID:200068 NCBI chrNW_004624818:2,751,724...2,789,145
Ensembl chrNW_004624818:2,751,724...2,779,999 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200068 NCBI chrNW_004624815:1,290,106...1,376,961
Ensembl chrNW_004624815:1,289,997...1,369,610 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 ISO PID PID:200068 NCBI chrNW_004624908:1,513,916...1,523,723
Ensembl chrNW_004624908:1,513,969...1,523,295 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO PID PID:200068 NCBI chrNW_004624756:21,806,570...21,837,351
Ensembl chrNW_004624756:21,805,599...21,830,699 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 ISO PID PID:200068 NCBI chrNW_004624817:7,909,777...7,913,419
Ensembl chrNW_004624817:7,909,468...7,913,417 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b ISO RGD
PID		 PMID:17403612 PMID:19961901 PID:200068 RGD:4143170 RGD:4143171 NCBI chrNW_004624758:18,464,005...18,498,740 JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO RGD
PID		 PMID:17403612 PMID:19385008 PMID:19961901 PID:200068 RGD:2312745 RGD:4143170 RGD:4143171 NCBI chrNW_004624730:50,534,284...50,550,279
Ensembl chrNW_004624730:50,531,915...50,550,528 		JBrowse link
G Tradd TNFRSF1A associated via death domain ISO PID PID:200068 NCBI chrNW_004624746:19,155,058...19,165,702
Ensembl chrNW_004624746:19,155,113...19,165,705 		JBrowse link
G Traf2 TNF receptor associated factor 2 ISO PID PID:200068 NCBI chrNW_004624760:952,574...973,511
Ensembl chrNW_004624760:952,574...965,661 		JBrowse link
tumor necrosis factor mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO PID
RGD		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624969:212,089...254,532
Ensembl chrNW_004624969:212,321...253,328 		JBrowse link
G Bag4 BAG cochaperone 4 ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624780:5,425,607...5,472,916
Ensembl chrNW_004624780:5,425,607...5,472,849 		JBrowse link
G Birc2 baculoviral IAP repeat containing 2 ISO PID
RGD		 PMID:23085193 PID:200102 RGD:7800730 NCBI chrNW_004624878:476,460...514,637 JBrowse link
G Birc3 baculoviral IAP repeat containing 3 ISO RGD
PID		 PMID:23085193 PID:200102 RGD:7800730 NCBI chrNW_004624878:516,750...541,475
Ensembl chrNW_004624878:523,300...536,062 		JBrowse link
G Casp8 caspase 8 ISO PID PID:200102 NCBI chrNW_004624899:427,064...450,931
Ensembl chrNW_004624899:424,363...451,087 		JBrowse link
G Cav1 caveolin 1 ISO PID PID:200102 NCBI chrNW_004624827:2,844,855...2,878,367
Ensembl chrNW_004624827:2,844,115...2,879,179 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624737:12,022,081...12,052,128
Ensembl chrNW_004624737:12,022,419...12,052,131 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase ISO PID
RGD		 PMID:21119682 PMID:23312890 PID:200102 RGD:7800734 RGD:7800735 NCBI chrNW_004624757:5,895,912...5,953,485 JBrowse link
G Fadd Fas associated via death domain ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624767:17,050,929...17,059,648
Ensembl chrNW_004624767:17,055,509...17,059,705 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624780:922,524...978,687
Ensembl chrNW_004624780:923,744...970,519 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624946:997,571...1,015,748
Ensembl chrNW_004624946:996,814...1,013,379 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase ISO RGD PMID:21119682 PMID:23312890 RGD:7800734 RGD:7800735 NCBI chrNW_004624842:4,840,848...4,977,785
Ensembl chrNW_004624842:4,842,419...4,935,699 		JBrowse link
G Madd MAP kinase activating death domain ISO PID PID:200102 NCBI chrNW_004624767:1,421,603...1,459,738
Ensembl chrNW_004624767:1,421,603...1,459,507 		JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 ISO PID PID:200102 NCBI chrNW_004624849:5,007,185...5,034,488
Ensembl chrNW_004624849:5,006,513...5,035,747 		JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 ISO PID PID:200102 NCBI chrNW_004624828:869,424...878,358
Ensembl chrNW_004624828:869,425...878,231 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200102 NCBI chrNW_004624759:2,360,655...2,429,189
Ensembl chrNW_004624759:2,363,076...2,428,273 		JBrowse link
G Map3k3 mitogen-activated protein kinase kinase kinase 3 ISO PID PID:200102 NCBI chrNW_004624849:1,118,275...1,186,244
Ensembl chrNW_004624849:1,118,492...1,185,777 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO PID PID:200102 NCBI chrNW_004624886:970,415...1,189,595
Ensembl chrNW_004624886:969,623...1,190,709 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 ISO RGD
PID		 PMID:21135871 PID:200102 RGD:5490225 NCBI chrNW_004624799:3,554,644...3,623,317
Ensembl chrNW_004624799:3,554,678...3,622,289 		JBrowse link
G Map4k2 mitogen-activated protein kinase kinase kinase kinase 2 ISO PID PID:200102 NCBI chrNW_004624767:21,585,634...21,597,222
Ensembl chrNW_004624767:21,585,666...21,597,220 		JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 ISO PID PID:200102 NCBI chrNW_004624738:20,716,430...20,874,930
Ensembl chrNW_004624738:20,715,296...20,875,393 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 ISO PID PID:200102 NCBI chrNW_004624749:6,332,686...6,495,942
Ensembl chrNW_004624749:6,332,534...6,495,942 		JBrowse link
G Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 ISO PID PID:200102 NCBI chrNW_004624731:18,362,856...18,460,761 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO PID PID:200102 NCBI chrNW_004624830:5,334,273...5,430,887
Ensembl chrNW_004624830:5,333,616...5,408,723 		JBrowse link
G Nrk Nik related kinase ISO PID PID:200102 NCBI chrNW_004624803:10,719,694...10,861,120 JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor ISO PID PID:200102 NCBI chrNW_004624744:33,439,068...33,528,413 JBrowse link
G Prkci protein kinase C iota ISO PID PID:200102 NCBI chrNW_004624730:48,258,524...48,340,217 JBrowse link
G Prkcz protein kinase C zeta ISO PID PID:200102 NCBI chrNW_004624818:7,758,192...7,846,950
Ensembl chrNW_004624818:7,759,770...7,847,208 		JBrowse link
G Rack1 receptor for activated C kinase 1 ISO PID PID:200102 NCBI chrNW_004624958:181,325...185,620
Ensembl chrNW_004624958:181,273...185,620 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 ISO RGD PMID:23085193 RGD:7800730 NCBI chrNW_004624741:1,503,017...1,523,542
Ensembl chrNW_004624741:1,502,942...1,523,675 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO PID PID:200102 NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272 		JBrowse link
G Rffl ring finger and FYVE like domain containing E3 ubiquitin protein ligase ISO PID PID:200102 NCBI chrNW_004624875:2,896,888...2,964,838
Ensembl chrNW_004624875:2,897,832...2,964,866 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO PID
RGD		 PMID:12655295 PMID:23085193 PID:200102 RGD:2292150 RGD:7800730 NCBI chrNW_004624756:21,806,570...21,837,351
Ensembl chrNW_004624756:21,805,599...21,830,699 		JBrowse link
G Rnf11 ring finger protein 11 ISO RGD PMID:21119682 PMID:23312890 RGD:7800734 RGD:7800735 NCBI chrNW_004624859:1,813,537...1,858,256
Ensembl chrNW_004624859:1,815,280...1,858,026 		JBrowse link
G Rnf31 ring finger protein 31 ISO RGD PMID:23085193 RGD:7800730 NCBI chrNW_004624820:8,376,530...8,388,596
Ensembl chrNW_004624820:8,375,871...8,388,569 		JBrowse link
G Sharpin SHANK associated RH domain interactor ISO RGD PMID:23085193 RGD:7800730 NCBI chrNW_004624735:12,719,196...12,723,578
Ensembl chrNW_004624735:12,719,762...12,723,348 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 ISO PID PID:200102 NCBI chrNW_004624817:7,909,777...7,913,419
Ensembl chrNW_004624817:7,909,468...7,913,417 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 ISO PID PID:200102 NCBI chrNW_004624916:697,861...701,015
Ensembl chrNW_004624916:697,006...701,012 		JBrowse link
G Sqstm1 sequestosome 1 ISO PID PID:200102 NCBI chrNW_004624733:42,689,454...42,700,916
Ensembl chrNW_004624733:42,691,841...42,700,916 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO PID PID:200102 NCBI chrNW_004624854:5,067,578...5,106,052
Ensembl chrNW_004624854:5,067,535...5,102,106 		JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO PID
RGD		 PMID:21135871 PID:200102 RGD:5490225 NCBI chrNW_004624752:8,912,467...8,937,313
Ensembl chrNW_004624752:8,913,900...8,937,329 		JBrowse link
G Tab2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 ISO RGD
PID		 PMID:21135871 PID:200102 RGD:5490225 NCBI chrNW_004624785:8,690,039...8,747,160 JBrowse link
G Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 ISO RGD PMID:21135871 RGD:5490225 NCBI chrNW_004624762:25,107,234...25,177,268 JBrowse link
G Tax1bp1 Tax1 binding protein 1 ISO RGD PMID:21119682 PMID:23312890 RGD:7800734 RGD:7800735 NCBI chrNW_004624739:2,800,453...2,894,355
Ensembl chrNW_004624739:2,801,301...2,885,094 		JBrowse link
G Tnf tumor necrosis factor ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO RGD
PID		 PMID:12655295 PMID:20967881 PID:200102 RGD:2292150 RGD:5130945 NCBI chrNW_004624860:3,111,244...3,123,041
Ensembl chrNW_004624860:3,111,630...3,122,711 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO PID
RGD		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624818:894,470...922,806
Ensembl chrNW_004624818:896,150...922,710 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase ISO PID PID:200102 NCBI chrNW_004624730:49,087,876...49,497,981
Ensembl chrNW_004624730:49,090,222...49,497,646 		JBrowse link
G Tradd TNFRSF1A associated via death domain ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chrNW_004624746:19,155,058...19,165,702
Ensembl chrNW_004624746:19,155,113...19,165,705 		JBrowse link
G Traf1 TNF receptor associated factor 1 ISO PID PID:200102 NCBI chrNW_004624760:14,423,735...14,445,033
Ensembl chrNW_004624760:14,424,157...14,446,084 		JBrowse link
G Traf2 TNF receptor associated factor 2 ISO PID
RGD		 PMID:12655295 PMID:20967881 PMID:23085193 PID:200102 RGD:2292150 RGD:5130945 RGD:7800730 NCBI chrNW_004624760:952,574...973,511
Ensembl chrNW_004624760:952,574...965,661 		JBrowse link
G Traf5 TNF receptor associated factor 5 ISO RGD PMID:23085193 RGD:7800730 NCBI chrNW_004624807:878,275...921,683
Ensembl chrNW_004624807:878,665...898,558 		JBrowse link
G Txn thioredoxin ISO PID PID:200102 NCBI chrNW_004624758:1,318,108...1,329,011
Ensembl chrNW_004624758:1,318,529...1,329,011 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3916
    regulatory pathway 2425
      cell death pathway 177
        altered cell death pathway + 2
        non-programmed cell death pathway + 0
        programmed cell death pathway + 177
paths to the root