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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:cell death pathway
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Accession:PW:0000275 term browser browse the term
Definition:A cell death pathway represents the particular series of events leading to the demise of a whole cell or parts of its contents. It plays an essential role in cellular and tissue homeostasis. Biochemical and morphological characteristics are used in the classification of various forms of cell death. Deregulation of cell death can contribute to the development of cancer and neurodegeneration.
Synonyms:related_synonym: cell death


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altered mitochondrial autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PINK1 PTEN induced kinase 1 TAS RGD PMID:24735649 RGD:10450527 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase TAS RGD PMID:24735649 RGD:10450527 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
apoptotic cell death pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 IEA KEGG hsa:04210 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 IEA KEGG hsa:04210 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,348...104,799,934 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 IEA KEGG hsa:04210 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G AKT3 AKT serine/threonine kinase 3 IEA KEGG hsa:04210 NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 IEA KEGG hsa:04210 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G ATM ATM serine/threonine kinase IEA KEGG hsa:04210 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G BAD BCL2 associated agonist of cell death IEA KEGG hsa:04210 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,828...64,291,946 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator IEA KEGG hsa:04210 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator IEA KEGG hsa:04210 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 IEA KEGG hsa:04210 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BID BH3 interacting domain death agonist IEA KEGG hsa:04210 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 IEA KEGG hsa:04210 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,208...102,378,680 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 IEA KEGG hsa:04210 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G CAPN1 calpain 1 IEA KEGG hsa:04210 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006 		JBrowse link
G CAPN2 calpain 2 IEA KEGG hsa:04210 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018 		JBrowse link
G CASP10 caspase 10 IEA KEGG hsa:04210 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,693...201,229,428 		JBrowse link
G CASP3 caspase 3 ISO
IEA 		KEGG
RGD		 PMID:10646526 hsa:04210, RGD:38596326 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,695...184,650,418 		JBrowse link
G CASP6 caspase 6 IEA KEGG hsa:04210 NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583 		JBrowse link
G CASP7 caspase 7 IEA KEGG hsa:04210 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,731,290 		JBrowse link
G CASP8 caspase 8 IEA KEGG hsa:04210 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 IEA KEGG hsa:04210 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator IEA KEGG hsa:04210 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CHP2 calcineurin like EF-hand protein 2 IEA KEGG hsa:04210 NCBI chr16:23,755,026...23,758,935
Ensembl chr16:23,754,618...23,758,951 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex IEA KEGG hsa:04210 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta IEA KEGG hsa:04210 NCBI chr22:36,913,628...36,940,439
Ensembl chr22:36,913,628...36,940,443 		JBrowse link
G CYCS cytochrome c, somatic IEA KEGG hsa:04210 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,266 		JBrowse link
G DFFA DNA fragmentation factor subunit alpha IEA KEGG hsa:04210 NCBI chr 1:10,456,522...10,472,529
Ensembl chr 1:10,456,522...10,472,549 		JBrowse link
G DFFB DNA fragmentation factor subunit beta IEA KEGG hsa:04210 NCBI chr 1:3,857,476...3,885,429
Ensembl chr 1:3,857,267...3,885,429 		JBrowse link
G ENDOG endonuclease G IEA KEGG hsa:04210 NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,461...128,822,676 		JBrowse link
G FADD Fas associated via death domain IEA KEGG hsa:04210 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,295...70,207,395 		JBrowse link
G FAS Fas cell surface death receptor IEA KEGG hsa:04210 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand IEA KEGG hsa:04210 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,102...172,666,876 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta IEA KEGG hsa:04210 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma IEA KEGG hsa:04210 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,179...154,565,047 		JBrowse link
G IL1A interleukin 1 alpha IEA KEGG hsa:04210 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta IEA KEGG hsa:04210 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 IEA KEGG hsa:04210 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,063,933...102,179,874 		JBrowse link
G IL1RAP interleukin 1 receptor accessory protein IEA KEGG hsa:04210 NCBI chr 3:190,514,085...190,659,750
Ensembl chr 3:190,514,051...190,659,750 		JBrowse link
G IL3 interleukin 3 IEA KEGG hsa:04210 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL3RA interleukin 3 receptor subunit alpha IEA KEGG hsa:04210 NCBI chr  X:1,336,785...1,382,689
NCBI chr  Y:1,336,785...1,382,689
Ensembl chr  Y:1,335,025...1,382,689
Ensembl chr  X:1,335,025...1,382,689 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 IEA KEGG hsa:04210 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,504...154,019,927 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 IEA KEGG hsa:04210 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,863...10,243,756 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 IEA KEGG hsa:04210 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,188,995...66,254,622 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 IEA KEGG hsa:04210 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G MAP3K14 mitogen-activated protein kinase kinase kinase 14 IEA KEGG hsa:04210 NCBI chr17:45,263,119...45,317,020
Ensembl chr17:45,263,119...45,317,112 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:26485208 RGD:12910856 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor IEA KEGG hsa:04210 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 IEA KEGG hsa:04210 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,500,937...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha IEA KEGG hsa:04210 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NGF nerve growth factor IEA KEGG hsa:04210 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IEA KEGG hsa:04210 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IEA KEGG hsa:04210 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta IEA KEGG hsa:04210 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,336...138,834,957 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IEA KEGG hsa:04210 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,730,117 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IEA KEGG hsa:04210 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IEA KEGG hsa:04210 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG hsa:04210 NCBI chr19:18,153,163...18,170,532
Ensembl chr19:18,153,160...18,170,541 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG hsa:04210 NCBI chr 1:46,040,140...46,174,901
Ensembl chr 1:46,040,140...46,133,338 		JBrowse link
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 IEA KEGG hsa:04210 NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,726 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha IEA KEGG hsa:04210 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta IEA KEGG hsa:04210 NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,418...73,496,026 		JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma IEA KEGG hsa:04210 NCBI chr 8:22,441,078...22,541,125
Ensembl chr 8:22,440,819...22,541,145 		JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha IEA KEGG hsa:04210 NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237 		JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta IEA KEGG hsa:04210 NCBI chr 9:101,591,604...101,594,969
Ensembl chr 9:101,591,604...101,595,021 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha IEA KEGG hsa:04210 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta IEA KEGG hsa:04210 NCBI chr 1:84,078,079...84,238,498
Ensembl chr 1:84,078,062...84,238,498 		JBrowse link
G PRKACG protein kinase cAMP-activated catalytic subunit gamma IEA KEGG hsa:04210 NCBI chr 9:69,012,504...69,014,113
Ensembl chr 9:69,012,504...69,014,113 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha IEA KEGG hsa:04210 NCBI chr17:68,413,623...68,551,316
Ensembl chr17:68,511,780...68,551,319 		JBrowse link
G PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta IEA KEGG hsa:04210 NCBI chr 7:549,197...728,934
Ensembl chr 7:549,196...728,268 		JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha IEA KEGG hsa:04210 NCBI chr 3:48,744,591...48,847,874
Ensembl chr 3:48,744,591...48,847,874 		JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta IEA KEGG hsa:04210 NCBI chr 7:107,044,705...107,161,811
Ensembl chr 7:107,044,627...107,161,811 		JBrowse link
G PRKX protein kinase cAMP-dependent X-linked catalytic subunit IEA KEGG hsa:04210 NCBI chr  X:3,604,340...3,713,649
Ensembl chr  X:3,604,340...3,713,649 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IEA KEGG hsa:04210 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 IEA KEGG hsa:04210 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G SMN1 survival of motor neuron 1, telomeric TAS RGD PMID:11303798 RGD:1358254 NCBI chr 5:70,924,941...70,966,375
Ensembl chr 5:70,925,030...70,953,942
Ensembl chr 5:70,925,030...70,953,942 		JBrowse link
G SNCA synuclein alpha ISO RGD PMID:16837598 RGD:13506279 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G TNF tumor necrosis factor IEA KEGG hsa:04210 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a IEA KEGG hsa:04210 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,121 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b IEA KEGG hsa:04210 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,071 		JBrowse link
G TNFRSF10C TNF receptor superfamily member 10c IEA KEGG hsa:04210 NCBI chr 8:23,102,921...23,117,445
Ensembl chr 8:23,102,921...23,118,759 		JBrowse link
G TNFRSF10D TNF receptor superfamily member 10d IEA KEGG hsa:04210 NCBI chr 8:23,135,588...23,164,027
Ensembl chr 8:23,135,588...23,164,027 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A IEA KEGG hsa:04210 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFSF10 TNF superfamily member 10 IEA KEGG hsa:04210 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,476 		JBrowse link
G TP53 tumor protein p53 IEA KEGG hsa:04210 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRADD TNFRSF1A associated via death domain IEA KEGG hsa:04210 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,153,969...67,163,760 		JBrowse link
G TRAF2 TNF receptor associated factor 2 IEA KEGG hsa:04210 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,903...136,929,221 		JBrowse link
G XIAP X-linked inhibitor of apoptosis IEA KEGG hsa:04210 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,693...123,913,972 		JBrowse link
autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP2 acid phosphatase 2, lysosomal ISO RGD PMID:18690537 RGD:4892631 NCBI chr11:47,239,302...47,248,814
Ensembl chr11:47,238,400...47,249,288 		JBrowse link
G ATG10 autophagy related 10 TAS RGD PMID:15325588 PMID:20034776 RGD:1643329, RGD:4889529 NCBI chr 5:81,972,023...82,256,133
Ensembl chr 5:81,971,615...82,276,857 		JBrowse link
G ATG12 autophagy related 12 TAS
IEA
ISO 		KEGG
RGD		 PMID:15325588 PMID:20034776 PMID:18059433 hsa:04140, RGD:1643329, RGD:4889529, RGD:2301217 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837 		JBrowse link
G ATG13 autophagy related 13 TAS RGD PMID:20034776 RGD:4889529 NCBI chr11:46,617,553...46,674,518
Ensembl chr11:46,617,251...46,674,818 		JBrowse link
G ATG14 autophagy related 14 TAS RGD PMID:20034776 RGD:4889529 NCBI chr14:55,366,391...55,411,830
Ensembl chr14:55,366,391...55,411,830 		JBrowse link
G ATG16L1 autophagy related 16 like 1 TAS RGD PMID:15325588 PMID:20034776 RGD:1643329, RGD:4889529 NCBI chr 2:233,251,673...233,295,669
Ensembl chr 2:233,210,051...233,295,674 		JBrowse link
G ATG16L2 autophagy related 16 like 2 TAS RGD PMID:15325588 PMID:20034776 RGD:1643329, RGD:4889529 NCBI chr11:72,814,411...72,843,740
Ensembl chr11:72,814,138...72,843,674 		JBrowse link
G ATG3 autophagy related 3 ISO
IEA
TAS 		KEGG
RGD		 PMID:17110912 PMID:20034776 PMID:15325588 hsa:04140, RGD:1643237, RGD:4889529, RGD:1643329 NCBI chr 3:112,532,510...112,561,962
Ensembl chr 3:112,532,510...112,562,046 		JBrowse link
G ATG4A autophagy related 4A cysteine peptidase TAS
IEA 		KEGG
RGD		 PMID:15325588 hsa:04140, RGD:1643329 NCBI chr  X:108,088,829...108,154,671
Ensembl chr  X:108,091,668...108,154,671 		JBrowse link
G ATG4B autophagy related 4B cysteine peptidase TAS
IEA 		KEGG
RGD		 PMID:15325588 hsa:04140, RGD:1643329 NCBI chr 2:241,637,693...241,673,857
Ensembl chr 2:241,637,213...241,673,857 		JBrowse link
G ATG4C autophagy related 4C cysteine peptidase TAS
IEA 		KEGG
RGD		 PMID:15325588 hsa:04140, RGD:1643329 NCBI chr 1:62,784,132...62,865,516
Ensembl chr 1:62,783,821...62,865,999 		JBrowse link
G ATG4D autophagy related 4D cysteine peptidase TAS
IEA 		KEGG
RGD		 PMID:15325588 hsa:04140, RGD:1643329 NCBI chr19:10,543,904...10,553,418
Ensembl chr19:10,543,533...10,553,423 		JBrowse link
G ATG5 autophagy related 5 TAS
IEA
ISO 		KEGG
RGD		 PMID:20034776 PMID:18059433 hsa:04140, RGD:4889529, RGD:2301217 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,326,477 		JBrowse link
G ATG7 autophagy related 7 TAS
ISO
IEA 		KEGG
RGD		 PMID:15325588 PMID:17665967 PMID:20034776 hsa:04140, RGD:1643329, RGD:1643198, RGD:4889529 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G ATG9A autophagy related 9A TAS RGD PMID:20034776 RGD:4889529 NCBI chr 2:219,219,380...219,229,636
Ensembl chr 2:219,219,380...219,229,717 		JBrowse link
G ATG9B autophagy related 9B TAS RGD PMID:20034776 RGD:4889529 NCBI chr 7:151,012,209...151,024,499
Ensembl chr 7:151,012,209...151,024,499 		JBrowse link
G BECN1 beclin 1 ISO
IEA
TAS 		KEGG
RGD		 PMID:16697404 PMID:20034776 PMID:15325588 hsa:04140, RGD:1643194, RGD:4889529, RGD:1643329 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,809,870...42,833,350 		JBrowse link
G CHMP2B charged multivesicular body protein 2B TAS RGD PMID:19535733 RGD:4892619 NCBI chr 3:87,227,309...87,255,556
Ensembl chr 3:87,227,271...87,255,556 		JBrowse link
G CHMP3 charged multivesicular body protein 3 TAS RGD PMID:19535733 RGD:4892619 NCBI chr 2:86,503,430...86,563,443
Ensembl chr 2:86,503,430...86,563,507 		JBrowse link
G GABARAP GABA type A receptor-associated protein TAS
IEA
IMP 		KEGG
RGD		 PMID:15325588 PMID:20562859 hsa:04140, RGD:1643329, RGD:4890444 NCBI chr17:7,240,008...7,242,449
Ensembl chr17:7,240,008...7,242,449 		JBrowse link
G GABARAPL1 GABA type A receptor associated protein like 1 IMP
IEA 		KEGG
RGD		 PMID:20562859 hsa:04140, RGD:4890444 NCBI chr12:10,212,877...10,223,128
Ensembl chr12:10,212,458...10,223,128 		JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 TAS
IEA
IMP 		KEGG
RGD		 PMID:15325588 PMID:20562859 hsa:04140, RGD:1643329, RGD:4890444 NCBI chr16:75,566,379...75,577,881
Ensembl chr16:75,566,375...75,577,881 		JBrowse link
G HGS hepatocyte growth factor-regulated tyrosine kinase substrate TAS RGD PMID:19535733 RGD:4892619 NCBI chr17:81,684,011...81,702,121
Ensembl chr17:81,683,326...81,703,138 		JBrowse link
G IFNA1 interferon alpha 1 IEA KEGG hsa:04140 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNA10 interferon alpha 10 IEA KEGG hsa:04140 NCBI chr 9:21,206,181...21,207,143
Ensembl chr 9:21,206,181...21,207,143 		JBrowse link
G IFNA13 interferon alpha 13 IEA KEGG hsa:04140 NCBI chr 9:21,367,372...21,368,057
Ensembl chr 9:21,367,372...21,368,057 		JBrowse link
G IFNA14 interferon alpha 14 IEA KEGG hsa:04140 NCBI chr 9:21,239,002...21,240,005
Ensembl chr 9:21,239,002...21,240,005 		JBrowse link
G IFNA16 interferon alpha 16 IEA KEGG hsa:04140 NCBI chr 9:21,216,373...21,217,311
Ensembl chr 9:21,216,373...21,217,311 		JBrowse link
G IFNA17 interferon alpha 17 IEA KEGG hsa:04140 NCBI chr 9:21,227,243...21,228,222
Ensembl chr 9:21,227,243...21,228,222 		JBrowse link
G IFNA2 interferon alpha 2 IEA KEGG hsa:04140 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IFNA21 interferon alpha 21 IEA KEGG hsa:04140 NCBI chr 9:21,165,637...21,166,660
Ensembl chr 9:21,165,637...21,166,660 		JBrowse link
G IFNA4 interferon alpha 4 IEA KEGG hsa:04140 NCBI chr 9:21,186,618...21,187,587
Ensembl chr 9:21,186,618...21,187,587 		JBrowse link
G IFNA5 interferon alpha 5 IEA KEGG hsa:04140 NCBI chr 9:21,304,326...21,305,313
Ensembl chr 9:21,304,326...21,305,313 		JBrowse link
G IFNA6 interferon alpha 6 IEA KEGG hsa:04140 NCBI chr 9:21,350,318...21,350,887
Ensembl chr 9:21,350,253...21,350,956 		JBrowse link
G IFNA7 interferon alpha 7 IEA KEGG hsa:04140 NCBI chr 9:21,201,469...21,202,205
Ensembl chr 9:21,201,469...21,202,205 		JBrowse link
G IFNA8 interferon alpha 8 IEA KEGG hsa:04140 NCBI chr 9:21,409,117...21,410,185
Ensembl chr 9:21,409,117...21,410,185 		JBrowse link
G IFNG interferon gamma IEA KEGG hsa:04140 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G INS insulin IEA KEGG hsa:04140 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 ISO RGD PMID:20548331 PMID:18690537 RGD:4892310, RGD:4892631 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,088...113,323,674 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO RGD PMID:20548331 RGD:4892310 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO
IMP
TAS 		RGD PMID:17665967 PMID:20562859 PMID:15325588 RGD:1643198, RGD:4890444, RGD:1643329 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,838...34,560,357 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta TAS
IMP 		RGD PMID:15325588 PMID:20562859 RGD:1643329, RGD:4890444 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,405,090 		JBrowse link
G MAP1LC3C microtubule associated protein 1 light chain 3 gamma IMP RGD PMID:20562859 RGD:4890444 NCBI chr 1:241,995,490...242,001,393
Ensembl chr 1:241,995,188...242,001,584 		JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 TAS
IEA 		KEGG
RGD		 PMID:20034776 hsa:04140, RGD:4889529 NCBI chr18:41,955,234...42,087,830
Ensembl chr18:41,955,207...42,087,830 		JBrowse link
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 TAS
IEA 		KEGG
RGD		 PMID:20034776 hsa:04140, RGD:4889529 NCBI chr 3:130,678,934...130,746,829
Ensembl chr 3:130,678,934...130,746,829 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 IEA KEGG hsa:04140 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 IEA KEGG hsa:04140 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family TAS RGD PMID:20548331 RGD:4892310 NCBI chr15:65,869,491...65,891,989
Ensembl chr15:65,726,054...65,891,989 		JBrowse link
G RAB33B RAB33B, member RAS oncogene family TAS RGD PMID:20548331 RGD:4892310 NCBI chr 4:139,438,376...139,476,609
Ensembl chr 4:139,453,232...139,476,609 		JBrowse link
G RAB5A RAB5A, member RAS oncogene family TAS RGD PMID:20548331 RGD:4892310 NCBI chr 3:19,947,097...19,985,175
Ensembl chr 3:19,947,097...19,985,178 		JBrowse link
G RAB7A RAB7A, member RAS oncogene family TAS RGD PMID:20548331 RGD:4892310 NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942 		JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 TAS RGD PMID:20034776 RGD:4889529 NCBI chr 8:52,622,458...52,714,435
Ensembl chr 8:52,622,458...52,745,843 		JBrowse link
G RUBCN rubicon autophagy regulator TAS RGD PMID:20034776 RGD:4889529 NCBI chr 3:197,668,867...197,749,820
Ensembl chr 3:197,668,867...197,749,727 		JBrowse link
G SNF8 SNF8 subunit of ESCRT-II TAS RGD PMID:19535733 RGD:4892619 NCBI chr17:48,929,316...48,944,842
Ensembl chr17:48,929,316...48,944,842 		JBrowse link
G TSG101 tumor susceptibility 101 TAS RGD PMID:19535733 RGD:4892619 NCBI chr11:18,480,311...18,526,942
Ensembl chr11:18,468,336...18,526,965 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 TAS
IEA 		KEGG
RGD		 PMID:15325588 PMID:20034776 hsa:04140, RGD:1643329, RGD:4889529 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,621...131,923,161 		JBrowse link
G ULK2 unc-51 like autophagy activating kinase 2 TAS
IEA 		KEGG
RGD		 PMID:20034776 hsa:04140, RGD:4889529 NCBI chr17:19,770,830...19,867,936
Ensembl chr17:19,770,829...19,867,937 		JBrowse link
G ULK3 unc-51 like kinase 3 IEA KEGG hsa:04140 NCBI chr15:74,836,118...74,843,156
Ensembl chr15:74,836,116...74,843,346 		JBrowse link
G UVRAG UV radiation resistance associated TAS RGD PMID:20034776 RGD:4889529 NCBI chr11:75,815,210...76,144,232
Ensembl chr11:75,815,180...76,144,259 		JBrowse link
G VAMP3 vesicle associated membrane protein 3 TAS RGD PMID:20548331 RGD:4892310 NCBI chr 1:7,771,296...7,781,432
Ensembl chr 1:7,771,296...7,781,432 		JBrowse link
G VAMP7 vesicle associated membrane protein 7 TAS RGD PMID:20548331 RGD:4892310 NCBI chr  X:155,881,345...155,943,769
NCBI chr  Y:57,067,865...57,130,289
Ensembl chr  Y:57,067,747...57,130,289
Ensembl chr  X:57,067,747...57,130,289 		JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A TAS RGD PMID:19535733 RGD:4892619 NCBI chr16:69,311,350...69,326,939
Ensembl chr16:69,311,336...69,326,939 		JBrowse link
chaperone mediated autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG1 BAG cochaperone 1 TAS RGD PMID:25724482 RGD:10755685 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720 		JBrowse link
G CTSB cathepsin B TAS RGD PMID:24323530 RGD:10755730 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSD cathepsin D TAS RGD PMID:25766616 PMID:24323530 RGD:10755729, RGD:10755730 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CTSL cathepsin L TAS RGD PMID:24323530 RGD:10755730 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 TAS RGD PMID:25724482 RGD:10755685 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,513,789...14,560,391 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 TAS RGD PMID:24281265 PMID:25724482 RGD:10755322, RGD:10755685 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587 		JBrowse link
G GFAP glial fibrillary acidic protein TAS RGD PMID:24281265 PMID:25724482 RGD:10755322, RGD:10755685 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 TAS RGD PMID:25724482 RGD:10755685 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 TAS RGD PMID:24281265 PMID:25724482 RGD:10755322, RGD:10755685 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,485...123,063,230 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 TAS RGD PMID:24281265 PMID:25724482 RGD:10755322, RGD:10755685 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G ST13 ST13 Hsp70 interacting protein TAS RGD PMID:25724482 RGD:10755685 NCBI chr22:40,824,535...40,856,639
Ensembl chr22:40,824,535...40,856,690 		JBrowse link
G STIP1 stress induced phosphoprotein 1 TAS RGD PMID:25724482 RGD:10755685 NCBI chr11:64,185,272...64,204,543
Ensembl chr11:64,185,272...64,204,548 		JBrowse link
extrinsic apoptotic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP10 caspase 10 TAS RGD PMID:17082813 RGD:2314187 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,693...201,229,428 		JBrowse link
G CASP3 caspase 3 TAS RGD PMID:17082813 RGD:2314187 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,695...184,650,418 		JBrowse link
G CASP7 caspase 7 TAS RGD PMID:17082813 RGD:2314187 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,731,290 		JBrowse link
G CASP8 caspase 8 TAS RGD PMID:17082813 RGD:2314187 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:17195944 RGD:1626509 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand ISO RGD PMID:16154149 RGD:1582433 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,102...172,666,876 		JBrowse link
FasL mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 EXP PID PID:200080 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,348...104,799,934 		JBrowse link
G BID BH3 interacting domain death agonist ISO
EXP
TAS 		PID
RGD		 PMID:18090083 PMID:19239902 PID:200080, RGD:2314002, RGD:4143196 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 EXP PID PID:200080 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,208...102,378,680 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 EXP PID PID:200080 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BTK Bruton tyrosine kinase EXP PID PID:200080 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G CASP10 caspase 10 EXP PID PID:200080 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,693...201,229,428 		JBrowse link
G CASP3 caspase 3 TAS
EXP 		PID
RGD		 PMID:19239902 PID:200080, RGD:4143196 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,695...184,650,418 		JBrowse link
G CASP7 caspase 7 TAS RGD PMID:19239902 RGD:4143196 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,731,290 		JBrowse link
G CASP8 caspase 8 ISO
EXP
TAS 		PID
RGD		 PMID:18090083 PMID:19239902 PID:200080, RGD:2314002, RGD:4143196 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator TAS
ISO
EXP 		PID
RGD		 PMID:19239902 PMID:19107989 PID:200080, RGD:4143196, RGD:8662854 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex EXP PID PID:200080 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CLTC clathrin heavy chain EXP PID PID:200080 NCBI chr17:59,619,895...59,696,956
Ensembl chr17:59,619,680...59,696,956 		JBrowse link
G EZR ezrin EXP PID PID:200080 NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,413 		JBrowse link
G FADD Fas associated via death domain TAS
EXP 		PID
RGD		 PMID:19239902 PID:200080, RGD:4143196 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,295...70,207,395 		JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 EXP PID PID:200080 NCBI chr12:49,866,896...49,903,900
Ensembl chr12:49,866,896...49,904,217 		JBrowse link
G FAS Fas cell surface death receptor ISO
EXP
TAS 		PID
RGD		 PMID:18090083 PMID:19107989 PMID:19239902 PID:200080, RGD:2314002, RGD:8662854, RGD:4143196 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand ISO
EXP
TAS 		PID
RGD		 PMID:18090083 PMID:19239902 PID:200080, RGD:2314002, RGD:4143196 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,102...172,666,876 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta EXP PID PID:200080 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma EXP PID PID:200080 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,179...154,565,047 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 EXP PID PID:200080 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,683...69,553,865 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 EXP PID PID:200080 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,480 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 EXP PID PID:200080 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,538...56,896,152 		JBrowse link
G MAPK10 mitogen-activated protein kinase 10 EXP PID PID:200080 NCBI chr 4:86,010,405...86,594,074
Ensembl chr 4:85,990,007...86,594,625 		JBrowse link
G MAPK11 mitogen-activated protein kinase 11 EXP PID PID:200080 NCBI chr22:50,263,713...50,270,380
Ensembl chr22:50,263,713...50,270,767 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 EXP PID PID:200080 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,738...36,122,511 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 EXP PID PID:200080 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 EXP PID PID:200080 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 EXP PID PID:200080 NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,978...2,603,190 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha EXP PID PID:200080 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta EXP PID PID:200080 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,336...138,834,957 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta EXP PID PID:200080 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,730,117 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 EXP PID PID:200080 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 EXP PID PID:200080 NCBI chr19:18,153,163...18,170,532
Ensembl chr19:18,153,160...18,170,541 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 EXP PID PID:200080 NCBI chr 1:46,040,140...46,174,901
Ensembl chr 1:46,040,140...46,133,338 		JBrowse link
G RFC1 replication factor C subunit 1 EXP PID PID:200080 NCBI chr 4:39,287,456...39,366,362
Ensembl chr 4:39,287,456...39,366,395 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 EXP PID PID:200080 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 EXP PID PID:200080 NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,414...6,394,998 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase EXP PID PID:200080 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,673...37,406,050 		JBrowse link
G SYK spleen associated tyrosine kinase EXP PID PID:200080 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,579...90,898,549 		JBrowse link
intrinsic apoptotic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 ISO RGD PMID:18931364 RGD:2313998 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO
TAS 		RGD PMID:15632274 PMID:19641503 RGD:1579966, RGD:2314029 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,828...64,291,946 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO
TAS 		RGD PMID:18817839 PMID:17322918 RGD:2313963, RGD:2313975 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,305 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO
TAS 		RGD PMID:15632274 PMID:18959742 PMID:18931364 PMID:17322918 PMID:18817839 RGD:1579966, RGD:2314140, RGD:2313998, RGD:2313975, RGD:2313963 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BBC3 BCL2 binding component 3 ISO
TAS 		RGD PMID:19095966 PMID:19641503 RGD:2313994, RGD:2314029 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,233,019 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO
TAS 		RGD PMID:15632274 PMID:18959742 PMID:18931364 PMID:17322918 RGD:1579966, RGD:2314140, RGD:2313998, RGD:2313975 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2A1 BCL2 related protein A1 TAS RGD PMID:17322918 RGD:2313975 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196 		JBrowse link
G BCL2L1 BCL2 like 1 ISO
TAS 		RGD PMID:15632274 PMID:18959742 PMID:17322918 RGD:1579966, RGD:2314140, RGD:2313975 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BCL2L10 BCL2 like 10 TAS RGD PMID:17322918 RGD:2313975 NCBI chr15:52,109,263...52,112,775
Ensembl chr15:52,109,263...52,112,775 		JBrowse link
G BCL2L11 BCL2 like 11 TAS RGD PMID:19641503 RGD:2314029 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444 		JBrowse link
G BCL2L2 BCL2 like 2 ISO
TAS 		RGD PMID:18817839 PMID:17322918 RGD:2313963, RGD:2313975 NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,313,069 		JBrowse link
G BID BH3 interacting domain death agonist ISO
TAS 		RGD PMID:18931364 PMID:19641503 PMID:18090083 RGD:2313998, RGD:2314029, RGD:2314002 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BIK BCL2 interacting killer TAS RGD PMID:19641503 RGD:2314029 NCBI chr22:43,110,750...43,129,712
Ensembl chr22:43,110,748...43,129,712 		JBrowse link
G BMF Bcl2 modifying factor TAS RGD PMID:19641503 RGD:2314029 NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,889...40,108,928 		JBrowse link
G BNIP1 BCL2 interacting protein 1 ISO
TAS 		RGD PMID:12714334 PMID:19641503 RGD:634759, RGD:2314029 NCBI chr 5:173,144,531...173,164,387
Ensembl chr 5:173,144,442...173,164,397 		JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO
TAS 		RGD PMID:14972662 PMID:19641503 RGD:2314028, RGD:2314029 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,966,461...131,981,984 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like TAS RGD PMID:19641503 RGD:2314029 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,037...26,505,636 		JBrowse link
G BOK BCL2 family apoptosis regulator BOK ISO
TAS 		RGD PMID:9356461 PMID:17322918 RGD:70678, RGD:2313975 NCBI chr 2:241,551,393...241,574,131
Ensembl chr 2:241,551,300...241,574,568 		JBrowse link
G CASP3 caspase 3 ISO
TAS 		RGD PMID:18817839 PMID:17869439 PMID:17082813 PMID:18090083 PMID:18931364 RGD:2313963, RGD:2314390, RGD:2314187, RGD:2314002, RGD:2313998 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,695...184,650,418 		JBrowse link
G CASP7 caspase 7 TAS RGD PMID:17082813 RGD:2314187 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,731,290 		JBrowse link
G CASP9 caspase 9 ISO
TAS 		RGD PMID:18817839 PMID:17869439 PMID:17082813 PMID:18090083 PMID:18931364 RGD:2313963, RGD:2314390, RGD:2314187, RGD:2314002, RGD:2313998 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CYCS cytochrome c, somatic ISO RGD PMID:18817839 PMID:18931364 RGD:2313963, RGD:2313998 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,266 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:17195944 RGD:1626509 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G HRK harakiri, BCL2 interacting protein ISO
TAS 		RGD PMID:10075695 PMID:19641503 PMID:17428807 RGD:70327, RGD:2314029, RGD:2290488 NCBI chr12:116,856,144...116,881,441
Ensembl chr12:116,856,144...116,881,441 		JBrowse link
G HTRA2 HtrA serine peptidase 2 ISO RGD PMID:16978742 RGD:2314385 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member ISO
TAS 		RGD PMID:9356461 PMID:17322918 RGD:70678, RGD:2313975 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 TAS
ISO 		RGD PMID:19641503 PMID:18959742 RGD:2314029, RGD:2314140 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,644...59,904,305 		JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO RGD PMID:17869439 RGD:2314390 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,693...123,913,972 		JBrowse link
mitochondrial autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 TAS RGD PMID:23065344 RGD:10401098 NCBI chr11:46,396,412...46,594,023
Ensembl chr11:46,396,414...46,594,125 		JBrowse link
G ATG7 autophagy related 7 TAS RGD PMID:25840011 RGD:10400888 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G ATXN3 ataxin 3 TAS RGD PMID:25995186 RGD:10401790 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,622 		JBrowse link
G BECN1 beclin 1 TAS RGD PMID:23065344 RGD:10401098 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,809,870...42,833,350 		JBrowse link
G BNIP3 BCL2 interacting protein 3 TAS RGD PMID:25840011 PMID:23065344 RGD:10400888, RGD:10401098 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,966,461...131,981,984 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like TAS RGD PMID:25840011 PMID:23065344 RGD:10400888, RGD:10401098 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,037...26,505,636 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 TAS RGD PMID:25840011 RGD:10400888 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 TAS RGD PMID:25840011 RGD:10400888 NCBI chr16:58,157,907...58,198,106
Ensembl chr16:58,157,907...58,198,191 		JBrowse link
G CSNK2B casein kinase 2 beta TAS RGD PMID:25840011 RGD:10400888 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343 		JBrowse link
G FUNDC1 FUN14 domain containing 1 TAS RGD PMID:25840011 RGD:10400888 NCBI chr  X:44,523,639...44,542,859
Ensembl chr  X:44,523,639...44,542,972 		JBrowse link
G OPTN optineurin TAS RGD PMID:25995186 RGD:10401790 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,140,320 		JBrowse link
G PARL presenilin associated rhomboid like TAS RGD PMID:25526784 RGD:10402124 NCBI chr 3:183,826,489...183,884,880
Ensembl chr 3:183,829,271...183,884,933 		JBrowse link
G PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase TAS RGD PMID:25840011 RGD:10400888 NCBI chr12:132,710,842...132,722,734
Ensembl chr12:132,710,786...132,722,734 		JBrowse link
G PINK1 PTEN induced kinase 1 TAS RGD PMID:25840011 PMID:25995186 PMID:23065344 RGD:10400888, RGD:10401790, RGD:10401098 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase TAS RGD PMID:25840011 PMID:25995186 PMID:23065344 RGD:10400888, RGD:10401790, RGD:10401098 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G SQSTM1 sequestosome 1 TAS RGD PMID:23065344 PMID:25995186 RGD:10401098, RGD:10401790 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase TAS RGD PMID:25840011 RGD:10400888 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,673...37,406,050 		JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 TAS RGD PMID:25526784 RGD:10402124 NCBI chr 7:22,812,974...22,822,849
Ensembl chr 7:22,812,628...22,822,849 		JBrowse link
G UBE2L3 ubiquitin conjugating enzyme E2 L3 TAS RGD PMID:25995186 RGD:10401790 NCBI chr22:21,549,447...21,624,034
Ensembl chr22:21,549,447...21,624,034 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 TAS RGD PMID:25840011 RGD:10400888 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,621...131,923,161 		JBrowse link
G USP15 ubiquitin specific peptidase 15 TAS RGD PMID:25995186 RGD:10401790 NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431 		JBrowse link
G USP30 ubiquitin specific peptidase 30 TAS RGD PMID:25995186 RGD:10401790 NCBI chr12:109,023,089...109,088,023
Ensembl chr12:109,023,089...109,088,023 		JBrowse link
G USP8 ubiquitin specific peptidase 8 TAS RGD PMID:25995186 RGD:10401790 NCBI chr15:50,424,405...50,514,421
Ensembl chr15:50,424,372...50,514,421 		JBrowse link
Trail mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BID BH3 interacting domain death agonist TAS RGD PMID:17403612 PMID:19961901 RGD:4143170, RGD:4143171 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CASP10 caspase 10 EXP PID PID:200068 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,693...201,229,428 		JBrowse link
G CASP3 caspase 3 TAS RGD PMID:17403612 PMID:19961901 RGD:4143170, RGD:4143171 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,695...184,650,418 		JBrowse link
G CASP7 caspase 7 TAS RGD PMID:19961901 RGD:4143171 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,731,290 		JBrowse link
G CASP8 caspase 8 TAS
EXP 		PID
RGD		 PMID:17403612 PMID:19961901 PID:200068, RGD:4143170, RGD:4143171 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator TAS
EXP 		PID
RGD		 PMID:17403612 PMID:19961901 PID:200068, RGD:4143170, RGD:4143171 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex EXP PID PID:200068 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G DAP3 death associated protein 3 EXP PID PID:200068 NCBI chr 1:155,687,948...155,739,010
Ensembl chr 1:155,687,833...155,739,014 		JBrowse link
G FADD Fas associated via death domain TAS
EXP 		PID
RGD		 PMID:17403612 PMID:19961901 PID:200068, RGD:4143170, RGD:4143171 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,295...70,207,395 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta EXP PID PID:200068 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma EXP PID PID:200068 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,179...154,565,047 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 EXP PID PID:200068 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,828...12,143,830 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 EXP PID PID:200068 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,538...56,896,152 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 EXP PID PID:200068 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,755,537...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 EXP PID PID:200068 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 EXP PID PID:200068 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha EXP PID PID:200068 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta EXP PID PID:200068 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,336...138,834,957 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta EXP PID PID:200068 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,730,117 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 EXP PID PID:200068 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 EXP PID PID:200068 NCBI chr19:18,153,163...18,170,532
Ensembl chr19:18,153,160...18,170,541 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 EXP PID PID:200068 NCBI chr 1:46,040,140...46,174,901
Ensembl chr 1:46,040,140...46,133,338 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 EXP PID PID:200068 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 EXP PID PID:200068 NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,414...6,394,998 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a TAS
EXP 		PID
RGD		 PMID:17403612 PMID:19961901 PID:200068, RGD:4143170, RGD:4143171 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,121 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b ISO
EXP
TAS 		PID
RGD		 PMID:19934367 PMID:19961901 PMID:17403612 PID:200068, RGD:4142856, RGD:4143171, RGD:4143170 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,071 		JBrowse link
G TNFRSF10C TNF receptor superfamily member 10c EXP PID PID:200068 NCBI chr 8:23,102,921...23,117,445
Ensembl chr 8:23,102,921...23,118,759 		JBrowse link
G TNFRSF10D TNF receptor superfamily member 10d EXP PID PID:200068 NCBI chr 8:23,135,588...23,164,027
Ensembl chr 8:23,135,588...23,164,027 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO
EXP
TAS 		PID
RGD		 PMID:19385008 PMID:19961901 PMID:17403612 PID:200068, RGD:2312745, RGD:4143171, RGD:4143170 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,476 		JBrowse link
G TRADD TNFRSF1A associated via death domain EXP PID PID:200068 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,153,969...67,163,760 		JBrowse link
G TRAF2 TNF receptor associated factor 2 EXP PID PID:200068 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,903...136,929,221 		JBrowse link
tumor necrosis factor mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G BAG4 BAG cochaperone 4 TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 EXP
TAS 		PID
RGD		 PMID:23085193 PID:200102, RGD:7800730 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,208...102,378,680 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 EXP
TAS 		PID
RGD		 PMID:23085193 PID:200102, RGD:7800730 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G CASP8 caspase 8 EXP PID PID:200102 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAV1 caveolin 1 EXP PID PID:200102 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase EXP
TAS 		PID
RGD		 PMID:21119682 PMID:23312890 PID:200102, RGD:7800735, RGD:7800734 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,032...50,801,935 		JBrowse link
G FADD Fas associated via death domain TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,295...70,207,395 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,179...154,565,047 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase TAS RGD PMID:23312890 PMID:21119682 RGD:7800734, RGD:7800735 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G MADD MAP kinase activating death domain EXP PID PID:200102 NCBI chr11:47,269,188...47,330,031
Ensembl chr11:47,269,161...47,330,038 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 EXP PID PID:200102 NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,240 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 EXP PID PID:200102 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,480 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 EXP PID PID:200102 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,538...56,896,152 		JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 EXP PID PID:200102 NCBI chr17:63,622,417...63,696,305
Ensembl chr17:63,622,381...63,696,305 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 EXP PID PID:200102 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,034...136,793,097 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 EXP
TAS 		PID
RGD		 PMID:21135871 PID:200102, RGD:5490225 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,093 		JBrowse link
G MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 EXP PID PID:200102 NCBI chr11:64,784,918...64,803,214
Ensembl chr11:64,784,918...64,803,241 		JBrowse link
G MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 EXP PID PID:200102 NCBI chr 2:39,249,266...39,437,285
Ensembl chr 2:39,249,266...39,437,324 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 EXP PID PID:200102 NCBI chr 2:101,697,707...101,894,690
Ensembl chr 2:101,696,850...101,894,690 		JBrowse link
G MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 EXP PID PID:200102 NCBI chr14:50,418,521...50,561,126
Ensembl chr14:50,417,845...50,561,126 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 EXP PID PID:200102 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,500,937...102,617,302 		JBrowse link
G NRK Nik related kinase EXP PID PID:200102 NCBI chr  X:105,821,786...105,958,610
Ensembl chr  X:105,822,394...105,958,611 		JBrowse link
G NSMAF neutral sphingomyelinase activation associated factor EXP PID PID:200102 NCBI chr 8:58,583,504...58,659,853
Ensembl chr 8:58,583,504...58,659,959 		JBrowse link
G PRKCI protein kinase C iota EXP PID PID:200102 NCBI chr 3:170,222,424...170,305,977
Ensembl chr 3:170,222,124...170,305,978 		JBrowse link
G PRKCZ protein kinase C zeta EXP PID PID:200102 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395 		JBrowse link
G RACK1 receptor for activated C kinase 1 EXP PID PID:200102 NCBI chr 5:181,236,897...181,243,906
Ensembl chr 5:181,236,897...181,248,096 		JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 TAS RGD PMID:23085193 RGD:7800730 NCBI chr20:408,299...432,139
Ensembl chr20:407,498...432,139 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit EXP PID PID:200102 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase EXP PID PID:200102 NCBI chr17:35,005,990...35,089,226
Ensembl chr17:35,005,990...35,089,899 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 TAS
EXP 		PID
RGD		 PMID:12655295 PMID:23085193 PID:200102, RGD:2292150, RGD:7800730 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RNF11 ring finger protein 11 TAS RGD PMID:23312890 PMID:21119682 RGD:7800734, RGD:7800735 NCBI chr 1:51,236,273...51,273,447
Ensembl chr 1:51,235,625...51,273,447 		JBrowse link
G RNF31 ring finger protein 31 TAS RGD PMID:23085193 RGD:7800730 NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660 		JBrowse link
G SHARPIN SHANK associated RH domain interactor TAS RGD PMID:23085193 RGD:7800730 NCBI chr 8:144,098,637...144,103,773
Ensembl chr 8:144,097,513...144,108,124 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 EXP PID PID:200102 NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,414...6,394,998 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 EXP PID PID:200102 NCBI chr 6:109,440,724...109,443,919
Ensembl chr 6:109,440,678...109,443,920 		JBrowse link
G SQSTM1 sequestosome 1 EXP PID PID:200102 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 EXP PID PID:200102 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 EXP
TAS 		PID
RGD		 PMID:21135871 PID:200102, RGD:5490225 NCBI chr22:39,399,780...39,437,132
Ensembl chr22:39,399,778...39,437,060 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 EXP
TAS 		PID
RGD		 PMID:21135871 PID:200102, RGD:5490225 NCBI chr 6:149,217,926...149,411,607
Ensembl chr 6:149,218,641...149,411,613 		JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TAS RGD PMID:21135871 RGD:5490225 NCBI chr  X:30,827,442...30,889,254
Ensembl chr  X:30,827,442...30,975,084 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 TAS RGD PMID:23312890 PMID:21119682 RGD:7800734, RGD:7800735 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TNF tumor necrosis factor TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 EXP
TAS 		PID
RGD		 PMID:21119682 PMID:23312890 PID:200102, RGD:7800735, RGD:7800734 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,866,383...137,885,836 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A TAS
EXP
ISO 		PID
RGD		 PMID:12655295 PMID:20967881 PID:200102, RGD:2292150, RGD:5130945 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,977...12,209,228 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase EXP PID PID:200102 NCBI chr 3:171,058,414...171,460,408
Ensembl chr 3:171,058,414...171,460,408 		JBrowse link
G TRADD TNFRSF1A associated via death domain TAS
EXP 		PID
RGD		 PMID:12655295 PID:200102, RGD:2292150 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,153,969...67,163,760 		JBrowse link
G TRAF1 TNF receptor associated factor 1 EXP PID PID:200102 NCBI chr 9:120,902,393...120,929,171
Ensembl chr 9:120,902,393...120,931,875 		JBrowse link
G TRAF2 TNF receptor associated factor 2 TAS
EXP
ISO 		PID
RGD		 PMID:12655295 PMID:23085193 PMID:20967881 PID:200102, RGD:2292150, RGD:7800730, RGD:5130945 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,903...136,929,221 		JBrowse link
G TRAF5 TNF receptor associated factor 5 TAS RGD PMID:23085193 RGD:7800730 NCBI chr 1:211,326,635...211,374,946
Ensembl chr 1:211,326,325...211,375,036 		JBrowse link
G TXN thioredoxin EXP PID PID:200102 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,604 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    regulatory pathway 3599
      cell death pathway 250
        altered cell death pathway + 2
        non-programmed cell death pathway + 0
        programmed cell death pathway + 250
paths to the root