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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:cell death pathway
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Accession:PW:0000275 term browser browse the term
Definition:A cell death pathway represents the particular series of events leading to the demise of a whole cell or parts of its contents. It plays an essential role in cellular and tissue homeostasis. Biochemical and morphological characteristics are used in the classification of various forms of cell death. Deregulation of cell death can contribute to the development of cancer and neurodegeneration.
Synonyms:related_synonym: cell death

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altered mitochondrial autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PINK1 PTEN induced kinase 1 ISO RGD PMID:24735649 RGD:10450527 NCBI chr20:111,902,135...111,919,082
Ensembl chr20:111,902,765...111,919,069 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24735649 RGD:10450527 NCBI chr13:88,856,056...90,329,379 JBrowse link
apoptotic cell death pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 ISO RGD PMID:10646526 RGD:38596326 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:26485208 RGD:12910856 NCBI chr20:119,787,700...119,818,455
Ensembl chr20:119,787,370...119,816,693 		JBrowse link
G SNCA synuclein alpha ISO RGD PMID:16837598 RGD:13506279 NCBI chr 7:38,083,154...38,194,068
Ensembl chr 7:38,081,509...38,191,479 		JBrowse link
autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP2 acid phosphatase 2, lysosomal ISO RGD PMID:18690537 RGD:4892631 NCBI chr 1:18,061,094...18,070,929
Ensembl chr 1:18,060,994...18,072,208 		JBrowse link
G ATG10 autophagy related 10 ISO RGD PMID:15325588 PMID:20034776 RGD:1643329 RGD:4889529 NCBI chr 4:76,092,887...76,378,175
Ensembl chr 4:76,092,832...76,377,403 		JBrowse link
G ATG12 autophagy related 12 ISO RGD PMID:15325588 PMID:18059433 PMID:20034776 RGD:1643329 RGD:2301217 RGD:4889529 NCBI chr23:19,073,545...19,087,603
Ensembl chr23:19,072,401...19,087,625 		JBrowse link
G ATG13 autophagy related 13 ISO RGD PMID:20034776 RGD:4889529 NCBI chr 1:18,651,872...18,712,395
Ensembl chr 1:18,652,998...18,712,482 		JBrowse link
G ATG14 autophagy related 14 ISO RGD PMID:20034776 RGD:4889529 NCBI chr24:32,560,580...32,605,336
Ensembl chr24:32,559,955...32,605,282 		JBrowse link
G ATG16L1 autophagy related 16 like 1 ISO RGD PMID:15325588 PMID:20034776 RGD:1643329 RGD:4889529 NCBI chr10:119,286,609...119,331,226
Ensembl chr10:119,286,751...119,333,267 		JBrowse link
G ATG16L2 autophagy related 16 like 2 ISO RGD PMID:15325588 PMID:20034776 RGD:1643329 RGD:4889529 NCBI chr 1:64,051,793...64,066,204
Ensembl chr 1:64,052,390...64,065,972 		JBrowse link
G ATG3 autophagy related 3 ISO RGD PMID:15325588 PMID:17110912 PMID:20034776 RGD:1643237 RGD:1643329 RGD:4889529 NCBI chr22:68,227,772...68,256,555
Ensembl chr22:68,228,203...68,257,503 		JBrowse link
G ATG4A autophagy related 4A cysteine peptidase ISO RGD PMID:15325588 RGD:1643329 NCBI chr  X:95,936,385...96,011,541
Ensembl chr  X:95,983,662...96,010,578 		JBrowse link
G ATG4B autophagy related 4B cysteine peptidase ISO RGD PMID:15325588 RGD:1643329 NCBI chr10:127,689,577...127,720,232 JBrowse link
G ATG4C autophagy related 4C cysteine peptidase ISO RGD PMID:15325588 RGD:1643329 NCBI chr20:70,209,536...70,291,750
Ensembl chr20:70,208,716...70,291,718 		JBrowse link
G ATG4D autophagy related 4D cysteine peptidase ISO RGD PMID:15325588 RGD:1643329 NCBI chr 6:9,555,792...9,565,295
Ensembl chr 6:9,555,780...9,568,814 		JBrowse link
G ATG5 autophagy related 5 ISO RGD PMID:18059433 PMID:20034776 RGD:2301217 RGD:4889529 NCBI chr13:67,482,538...67,619,201
Ensembl chr13:67,482,595...67,617,902 		JBrowse link
G ATG7 autophagy related 7 ISO RGD PMID:15325588 PMID:17665967 PMID:20034776 RGD:1643198 RGD:1643329 RGD:4889529 NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070 		JBrowse link
G ATG9A autophagy related 9A ISO RGD PMID:20034776 RGD:4889529 NCBI chr10:105,123,039...105,133,057
Ensembl chr10:105,124,412...105,131,409 		JBrowse link
G ATG9B autophagy related 9B ISO RGD PMID:20034776 RGD:4889529 NCBI chr21:119,197,387...119,209,578
Ensembl chr21:119,198,125...119,206,599 		JBrowse link
G BECN1 beclin 1 ISO RGD PMID:15325588 PMID:16697404 PMID:20034776 RGD:1643194 RGD:1643329 RGD:4889529 NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322 		JBrowse link
G CHMP2B charged multivesicular body protein 2B ISO RGD PMID:19535733 RGD:4892619 NCBI chr22:89,672,043...89,701,801
Ensembl chr22:89,672,022...89,701,897 		JBrowse link
G CHMP3 charged multivesicular body protein 3 ISO RGD PMID:19535733 RGD:4892619 NCBI chr14:20,536,490...20,654,761
Ensembl chr14:20,594,817...20,654,404 		JBrowse link
G GABARAP GABA type A receptor-associated protein ISO RGD PMID:15325588 PMID:20562859 RGD:1643329 RGD:4890444 NCBI chr16:6,614,478...6,616,516
Ensembl chr16:6,614,688...6,616,443 		JBrowse link
G GABARAPL1 GABA type A receptor associated protein like 1 ISO RGD PMID:20562859 RGD:4890444 NCBI chr11:10,087,582...10,099,125
Ensembl chr11:10,087,604...10,096,612 		JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 ISO RGD PMID:15325588 PMID:20562859 RGD:1643329 RGD:4890444 NCBI chr 5:61,053,283...61,078,675
Ensembl chr 5:61,053,262...61,066,083 		JBrowse link
G HGS hepatocyte growth factor-regulated tyrosine kinase substrate ISO RGD PMID:19535733 RGD:4892619 NCBI chr16:73,613,711...73,632,527
Ensembl chr16:73,613,786...73,632,016 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 ISO RGD PMID:18690537 PMID:20548331 RGD:4892310 RGD:4892631 NCBI chr 3:91,295,758...91,319,881
Ensembl chr 3:91,295,681...91,321,333 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO RGD PMID:20548331 RGD:4892310
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:15325588 PMID:17665967 PMID:20562859 RGD:1643198 RGD:1643329 RGD:4890444 NCBI chr 2:38,857,235...38,858,955
Ensembl chr 2:38,857,299...38,858,505 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta ISO RGD PMID:15325588 PMID:20562859 RGD:1643329 RGD:4890444 NCBI chr 5:72,762,428...72,774,204
Ensembl chr 5:72,763,050...72,772,770 		JBrowse link
G MAP1LC3C microtubule associated protein 1 light chain 3 gamma ISO RGD PMID:20562859 RGD:4890444 NCBI chr25:79,079,750...79,084,248
Ensembl chr25:79,080,728...79,083,762 		JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 ISO RGD PMID:20034776 RGD:4889529 NCBI chr18:38,785,476...38,914,279
Ensembl chr18:38,787,717...38,914,185 		JBrowse link
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 ISO RGD PMID:20034776 RGD:4889529 NCBI chr15:59,444,570...59,515,619
Ensembl chr15:59,444,616...59,515,240 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family ISO RGD PMID:20548331 RGD:4892310 NCBI chr26:17,682,629...17,702,325
Ensembl chr26:17,682,874...17,702,309 		JBrowse link
G RAB33B RAB33B, member RAS oncogene family ISO RGD PMID:20548331 RGD:4892310 NCBI chr 7:86,422,234...86,446,341
Ensembl chr 7:86,422,612...86,446,338 		JBrowse link
G RAB5A RAB5A, member RAS oncogene family ISO RGD PMID:20548331 RGD:4892310 NCBI chr15:64,678,910...64,715,228
Ensembl chr15:64,682,723...64,713,928 		JBrowse link
G RAB7A RAB7A, member RAS oncogene family ISO RGD PMID:20548331 RGD:4892310 NCBI chr22:52,231,481...52,309,276
Ensembl chr22:52,230,835...52,309,306 		JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 ISO RGD PMID:20034776 RGD:4889529 NCBI chr 8:48,726,551...48,818,027
Ensembl chr 8:48,724,393...48,817,928 		JBrowse link
G RUBCN rubicon autophagy regulator ISO RGD PMID:20034776 RGD:4889529 NCBI chr15:91,401,565...91,468,837
Ensembl chr15:91,400,031...91,457,933 		JBrowse link
G SNF8 SNF8 subunit of ESCRT-II ISO RGD PMID:19535733 RGD:4892619 NCBI chr16:69,343,260...69,357,843
Ensembl chr16:69,339,804...69,357,860 		JBrowse link
G TSG101 tumor susceptibility 101 ISO RGD PMID:19535733 RGD:4892619 NCBI chr 1:46,401,889...46,451,122
Ensembl chr 1:46,402,024...46,450,916 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 ISO RGD PMID:15325588 PMID:20034776 RGD:1643329 RGD:4889529 NCBI chr11:127,276,172...127,304,270
Ensembl chr11:127,276,210...127,304,497 		JBrowse link
G ULK2 unc-51 like autophagy activating kinase 2 ISO RGD PMID:20034776 RGD:4889529 NCBI chr16:18,335,095...18,434,031
Ensembl chr16:18,335,235...18,433,578 		JBrowse link
G UVRAG UV radiation resistance associated ISO RGD PMID:20034776 RGD:4889529 NCBI chr 1:67,032,575...67,353,207
Ensembl chr 1:67,032,436...67,353,166 		JBrowse link
G VAMP3 vesicle associated membrane protein 3 ISO RGD PMID:20548331 RGD:4892310 NCBI chr20:123,973,672...123,984,230
Ensembl chr20:123,971,992...123,984,187 		JBrowse link
G VAMP7 vesicle associated membrane protein 7 ISO RGD PMID:20548331 RGD:4892310 NCBI chr  X:129,937,026...129,984,071
Ensembl chr  X:129,937,046...129,984,119 		JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A ISO RGD PMID:19535733 RGD:4892619 NCBI chr 5:58,081,800...58,095,115
Ensembl chr 5:58,082,521...58,095,173 		JBrowse link
chaperone mediated autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG1 BAG cochaperone 1 ISO RGD PMID:25724482 RGD:10755685 NCBI chr12:47,006,177...47,016,177 JBrowse link
G CTSB cathepsin B ISO RGD PMID:24323530 RGD:10755730 NCBI chr 8:7,246,076...7,269,655
Ensembl chr 8:7,246,013...7,268,854 		JBrowse link
G CTSD cathepsin D ISO RGD PMID:24323530 PMID:25766616 RGD:10755729 RGD:10755730 NCBI chr 1:1,570,163...1,581,857
Ensembl chr 1:1,570,069...1,581,833 		JBrowse link
G CTSL cathepsin L ISO RGD PMID:24323530 RGD:10755730 NCBI chr12:98,347,770...98,353,426
Ensembl chr12:98,347,800...98,353,467 		JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 ISO RGD PMID:25724482 RGD:10755685 NCBI chr 6:13,173,197...13,176,826
Ensembl chr 6:13,173,157...13,176,877 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:24281265 PMID:25724482 RGD:10755322 RGD:10755685 NCBI chr17:1,626,701...1,630,445
Ensembl chr17:1,627,901...1,630,150 		JBrowse link
G GFAP glial fibrillary acidic protein ISO RGD PMID:24281265 PMID:25724482 RGD:10755322 RGD:10755685 NCBI chr16:61,489,090...61,499,672
Ensembl chr16:61,489,421...61,500,646 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:25724482 RGD:10755685 NCBI chr24:80,016,352...80,019,130
Ensembl chr24:80,016,232...80,019,120 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:24281265 PMID:25724482 RGD:10755322 RGD:10755685 NCBI chr 1:114,447,348...114,452,693
Ensembl chr 1:114,446,544...114,451,562 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO RGD PMID:24281265 PMID:25724482 RGD:10755322 RGD:10755685
G ST13 ST13 Hsp70 interacting protein ISO RGD PMID:25724482 RGD:10755685 NCBI chr19:23,373,970...23,413,054
Ensembl chr19:23,375,723...23,412,742 		JBrowse link
G STIP1 stress induced phosphoprotein 1 ISO RGD PMID:25724482 RGD:10755685 NCBI chr 1:10,033,317...10,052,406 JBrowse link
extrinsic apoptotic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP10 caspase 10 ISO RGD PMID:17082813 RGD:2314187 NCBI chr10:86,830,101...86,884,729
Ensembl chr10:86,830,589...86,871,200 		JBrowse link
G CASP3 caspase 3 ISO RGD PMID:17082813 RGD:2314187 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G CASP7 caspase 7 ISO RGD PMID:17082813 RGD:2314187 NCBI chr 9:106,558,291...106,607,662
Ensembl chr 9:106,559,445...106,607,663 		JBrowse link
G CASP8 caspase 8 ISO RGD PMID:17082813 RGD:2314187 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G FASLG Fas ligand ISO RGD PMID:16154149 RGD:1582433 NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251 		JBrowse link
FasL mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200080 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G BID BH3 interacting domain death agonist ISO PID
RGD		 PMID:18090083 PMID:19239902 PID:200080 RGD:2314002 RGD:4143196
G BIRC2 baculoviral IAP repeat containing 2 ISO PID PID:200080 NCBI chr 1:93,721,449...93,746,638 JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ISO PID PID:200080 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G BTK Bruton tyrosine kinase ISO PID PID:200080 NCBI chr  X:89,690,569...89,727,420 JBrowse link
G CASP10 caspase 10 ISO PID PID:200080 NCBI chr10:86,830,101...86,884,729
Ensembl chr10:86,830,589...86,871,200 		JBrowse link
G CASP3 caspase 3 ISO PID
RGD		 PMID:19239902 PID:200080 RGD:4143196 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G CASP7 caspase 7 ISO RGD PMID:19239902 RGD:4143196 NCBI chr 9:106,558,291...106,607,662
Ensembl chr 9:106,559,445...106,607,663 		JBrowse link
G CASP8 caspase 8 ISO PID
RGD		 PMID:18090083 PMID:19239902 PID:200080 RGD:2314002 RGD:4143196 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD
PID		 PMID:19107989 PMID:19239902 PID:200080 RGD:4143196 RGD:8662854 NCBI chr10:86,768,252...86,819,963
Ensembl chr10:86,782,240...86,816,652 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO PID PID:200080 NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700 		JBrowse link
G CLTC clathrin heavy chain ISO PID PID:200080 NCBI chr16:33,751,641...33,826,415
Ensembl chr16:33,752,556...33,799,102 		JBrowse link
G EZR ezrin ISO PID PID:200080 NCBI chr13:86,342,954...86,399,827
Ensembl chr13:86,344,051...86,370,622 		JBrowse link
G FADD Fas associated via death domain ISO RGD
PID		 PMID:19239902 PID:200080 RGD:4143196 NCBI chr 1:4,358,314...4,361,863 JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 ISO PID PID:200080 NCBI chr11:46,100,437...46,131,046
Ensembl chr11:46,099,895...46,131,155 		JBrowse link
G FASLG Fas ligand ISO RGD
PID		 PMID:18090083 PMID:19239902 PID:200080 RGD:2314002 RGD:4143196 NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO PID PID:200080 NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381 		JBrowse link
G LOC103232832 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO PID PID:200080 NCBI chr  X:128,781,975...128,816,039
Ensembl chr  X:128,787,785...128,806,083 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 ISO PID PID:200080 NCBI chr16:52,045,398...52,188,416
Ensembl chr16:52,057,784...52,187,997 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO PID PID:200080 NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200080 NCBI chr 4:53,040,731...53,120,784
Ensembl chr 4:53,084,023...53,120,772 		JBrowse link
G MAPK10 mitogen-activated protein kinase 10 ISO PID PID:200080 NCBI chr 7:34,394,600...34,725,658
Ensembl chr 7:34,399,544...34,564,212 		JBrowse link
G MAPK11 mitogen-activated protein kinase 11 ISO PID PID:200080 NCBI chr19:32,754,261...32,760,859
Ensembl chr19:32,752,546...32,760,798 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO PID PID:200080 NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO PID PID:200080 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO PID PID:200080 NCBI chr23:81,965,330...82,026,414
Ensembl chr23:81,963,899...82,013,659 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO PID PID:200080
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200080 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO PID PID:200080 NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO PID PID:200080 NCBI chr20:122,040,131...122,111,397
Ensembl chr20:122,041,963...122,078,504 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200080 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 ISO PID PID:200080 NCBI chr 6:16,620,673...16,637,511
Ensembl chr 6:16,621,606...16,636,937 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 ISO PID PID:200080 NCBI chr20:86,651,692...86,748,670
Ensembl chr20:86,651,520...86,745,116 		JBrowse link
G RFC1 replication factor C subunit 1 ISO PID PID:200080 NCBI chr27:10,936,445...11,013,457
Ensembl chr27:10,936,461...11,006,679 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 ISO PID PID:200080 NCBI chr17:69,065,509...69,117,825
Ensembl chr17:69,063,047...69,105,348 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 ISO PID PID:200080 NCBI chr 1:58,431,677...58,436,233
Ensembl chr 1:58,432,068...58,436,236 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200080 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G SYK spleen associated tyrosine kinase ISO PID PID:200080 NCBI chr12:101,254,085...101,374,724
Ensembl chr12:101,260,061...101,349,856 		JBrowse link
intrinsic apoptotic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 ISO RGD PMID:18931364 RGD:2313998 NCBI chr11:93,942,137...94,024,728
Ensembl chr11:93,942,103...94,024,457 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO RGD PMID:15632274 PMID:19641503 RGD:1579966 RGD:2314029 NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO RGD PMID:17322918 PMID:18817839 RGD:2313963 RGD:2313975 NCBI chr17:38,492,776...38,502,534
Ensembl chr17:38,492,858...38,501,281 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO RGD PMID:15632274 PMID:17322918 PMID:18817839 PMID:18931364 PMID:18959742 RGD:1579966 RGD:2313963 RGD:2313975 RGD:2313998 RGD:2314140 NCBI chr 6:42,186,028...42,193,105 JBrowse link
G BBC3 BCL2 binding component 3 ISO RGD PMID:19095966 PMID:19641503 RGD:2313994 RGD:2314029 NCBI chr 6:40,560,550...40,572,428
Ensembl chr 6:40,561,274...40,567,853 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO RGD PMID:15632274 PMID:17322918 PMID:18931364 PMID:18959742 RGD:1579966 RGD:2313975 RGD:2313998 RGD:2314140 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BCL2A1 BCL2 related protein A1 ISO RGD PMID:17322918 RGD:2313975 NCBI chr26:3,451,773...3,461,215
Ensembl chr26:3,451,873...3,461,180 		JBrowse link
G BCL2L1 BCL2 like 1 ISO RGD PMID:15632274 PMID:17322918 PMID:18959742 RGD:1579966 RGD:2313975 RGD:2314140 NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470 		JBrowse link
G BCL2L10 BCL2 like 10 ISO RGD PMID:17322918 RGD:2313975 NCBI chr26:31,274,015...31,277,377
Ensembl chr26:31,274,119...31,276,937 		JBrowse link
G BCL2L11 BCL2 like 11 ISO RGD PMID:19641503 RGD:2314029 NCBI chr14:14,178,159...14,205,337 JBrowse link
G BID BH3 interacting domain death agonist ISO RGD PMID:18090083 PMID:18931364 PMID:19641503 RGD:2313998 RGD:2314002 RGD:2314029
G BIK BCL2 interacting killer ISO RGD PMID:19641503 RGD:2314029 NCBI chr19:25,632,837...25,658,951
Ensembl chr19:25,652,945...25,658,541 		JBrowse link
G BMF Bcl2 modifying factor ISO RGD PMID:19641503 RGD:2314029 NCBI chr26:42,893,997...42,915,062
Ensembl chr26:42,894,460...42,915,062 		JBrowse link
G BNIP1 BCL2 interacting protein 1 ISO RGD PMID:12714334 PMID:19641503 RGD:2314029 RGD:634759 NCBI chr23:75,307,222...75,339,356
Ensembl chr23:75,307,304...75,327,256 		JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO RGD PMID:14972662 PMID:19641503 RGD:2314028 RGD:2314029 NCBI chr 9:124,570,958...124,586,002
Ensembl chr 9:124,568,695...124,585,980 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like ISO RGD PMID:19641503 RGD:2314029 NCBI chr 8:24,497,311...24,521,424
Ensembl chr 8:24,497,351...24,523,553 		JBrowse link
G BOK BCL2 family apoptosis regulator BOK ISO RGD PMID:9356461 PMID:17322918 RGD:2313975 RGD:70678 NCBI chr10:127,621,936...127,634,091
Ensembl chr10:127,622,149...127,635,833 		JBrowse link
G CASP3 caspase 3 ISO RGD PMID:17082813 PMID:17869439 PMID:18090083 PMID:18817839 PMID:18931364 RGD:2313963 RGD:2313998 RGD:2314002 RGD:2314187 RGD:2314390 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G CASP7 caspase 7 ISO RGD PMID:17082813 RGD:2314187 NCBI chr 9:106,558,291...106,607,662
Ensembl chr 9:106,559,445...106,607,663 		JBrowse link
G CASP9 caspase 9 ISO RGD PMID:17082813 PMID:17869439 PMID:18090083 PMID:18817839 PMID:18931364 RGD:2313963 RGD:2313998 RGD:2314002 RGD:2314187 RGD:2314390 NCBI chr20:116,772,819...116,798,402
Ensembl chr20:116,772,155...116,798,930 		JBrowse link
G CYCS cytochrome c, somatic ISO RGD PMID:18817839 PMID:18931364 RGD:2313963 RGD:2313998 NCBI chr21:33,251,825...33,253,298 JBrowse link
G HRK harakiri, BCL2 interacting protein ISO RGD PMID:10075695 PMID:17428807 PMID:19641503 RGD:2290488 RGD:2314029 RGD:70327 NCBI chr11:112,171,912...112,195,256
Ensembl chr11:112,193,561...112,193,836 		JBrowse link
G HTRA2 HtrA serine peptidase 2 ISO RGD PMID:16978742 RGD:2314385 NCBI chr14:32,745,436...32,749,176
Ensembl chr14:32,743,708...32,748,577 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member ISO RGD PMID:9356461 PMID:17322918 RGD:2313975 RGD:70678
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 ISO RGD PMID:18959742 PMID:19641503 RGD:2314029 RGD:2314140 NCBI chr18:19,861,182...19,865,628
Ensembl chr18:19,862,743...19,865,250 		JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO RGD PMID:17869439 RGD:2314390
mitochondrial autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 ISO RGD PMID:23065344 RGD:10401098 NCBI chr 1:18,777,807...18,932,784
Ensembl chr 1:18,734,926...18,932,785 		JBrowse link
G ATG7 autophagy related 7 ISO RGD PMID:25840011 RGD:10400888 NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070 		JBrowse link
G ATXN3 ataxin 3 ISO RGD PMID:25995186 RGD:10401790 NCBI chr24:69,810,433...69,855,308 JBrowse link
G BECN1 beclin 1 ISO RGD PMID:23065344 RGD:10401098 NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322 		JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO RGD PMID:23065344 PMID:25840011 RGD:10400888 RGD:10401098 NCBI chr 9:124,570,958...124,586,002
Ensembl chr 9:124,568,695...124,585,980 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like ISO RGD PMID:23065344 PMID:25840011 RGD:10400888 RGD:10401098 NCBI chr 8:24,497,311...24,521,424
Ensembl chr 8:24,497,351...24,523,553 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO RGD PMID:25840011 RGD:10400888 NCBI chr 2:55,982,259...56,047,023 JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 ISO RGD PMID:25840011 RGD:10400888 NCBI chr 5:44,093,320...44,133,352
Ensembl chr 5:44,093,215...44,133,335 		JBrowse link
G CSNK2B casein kinase 2 beta ISO RGD PMID:25840011 RGD:10400888 NCBI chr17:40,354,520...40,359,136
Ensembl chr17:40,352,367...40,358,401 		JBrowse link
G FUNDC1 FUN14 domain containing 1 ISO RGD PMID:25840011 RGD:10400888 NCBI chr  X:41,685,945...41,705,037 JBrowse link
G OPTN optineurin ISO RGD PMID:25995186 RGD:10401790 NCBI chr 9:13,142,036...13,176,996
Ensembl chr 9:13,150,426...13,177,021 		JBrowse link
G PARL presenilin associated rhomboid like ISO RGD PMID:25526784 RGD:10402124 NCBI chr15:5,536,556...5,589,522
Ensembl chr15:5,536,610...5,590,825 		JBrowse link
G PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase ISO RGD PMID:25840011 RGD:10400888 NCBI chr11:128,053,176...128,064,030
Ensembl chr11:128,053,795...128,065,720 		JBrowse link
G PINK1 PTEN induced kinase 1 ISO RGD PMID:23065344 PMID:25840011 PMID:25995186 RGD:10400888 RGD:10401098 RGD:10401790 NCBI chr20:111,902,135...111,919,082
Ensembl chr20:111,902,765...111,919,069 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:23065344 PMID:25840011 PMID:25995186 RGD:10400888 RGD:10401098 RGD:10401790 NCBI chr13:88,856,056...90,329,379 JBrowse link
G SQSTM1 sequestosome 1 ISO RGD PMID:23065344 PMID:25995186 RGD:10401098 RGD:10401790 NCBI chr23:81,536,271...81,571,061
Ensembl chr23:81,558,082...81,574,830 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:25840011 RGD:10400888 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 ISO RGD PMID:25526784 RGD:10402124 NCBI chr21:35,485,860...35,496,281
Ensembl chr21:35,485,685...35,497,325 		JBrowse link
G UBE2L3 ubiquitin conjugating enzyme E2 L3 ISO RGD PMID:25995186 RGD:10401790 NCBI chr19:4,485,960...4,538,838 JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 ISO RGD PMID:25840011 RGD:10400888 NCBI chr11:127,276,172...127,304,270
Ensembl chr11:127,276,210...127,304,497 		JBrowse link
G USP15 ubiquitin specific peptidase 15 ISO RGD PMID:25995186 RGD:10401790 NCBI chr11:58,154,905...58,300,431
Ensembl chr11:58,154,919...58,300,522 		JBrowse link
G USP30 ubiquitin specific peptidase 30 ISO RGD PMID:25995186 RGD:10401790 NCBI chr11:104,254,923...104,292,373
Ensembl chr11:104,255,012...104,290,273 		JBrowse link
G USP8 ubiquitin specific peptidase 8 ISO RGD PMID:25995186 RGD:10401790 NCBI chr26:32,829,627...32,906,493
Ensembl chr26:32,829,523...32,866,073 		JBrowse link
Trail mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BID BH3 interacting domain death agonist ISO RGD PMID:17403612 PMID:19961901 RGD:4143170 RGD:4143171
G CASP10 caspase 10 ISO PID PID:200068 NCBI chr10:86,830,101...86,884,729
Ensembl chr10:86,830,589...86,871,200 		JBrowse link
G CASP3 caspase 3 ISO RGD PMID:17403612 PMID:19961901 RGD:4143170 RGD:4143171 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G CASP7 caspase 7 ISO RGD PMID:19961901 RGD:4143171 NCBI chr 9:106,558,291...106,607,662
Ensembl chr 9:106,559,445...106,607,663 		JBrowse link
G CASP8 caspase 8 ISO PID
RGD		 PMID:17403612 PMID:19961901 PID:200068 RGD:4143170 RGD:4143171 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD
PID		 PMID:17403612 PMID:19961901 PID:200068 RGD:4143170 RGD:4143171 NCBI chr10:86,768,252...86,819,963
Ensembl chr10:86,782,240...86,816,652 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO PID PID:200068 NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700 		JBrowse link
G DAP3 death associated protein 3 ISO PID PID:200068 NCBI chr20:8,122,440...8,174,665
Ensembl chr20:8,128,014...8,173,852 		JBrowse link
G FADD Fas associated via death domain ISO PID
RGD		 PMID:17403612 PMID:19961901 PID:200068 RGD:4143170 RGD:4143171 NCBI chr 1:4,358,314...4,361,863 JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO PID PID:200068 NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381 		JBrowse link
G LOC103215471 tumor necrosis factor receptor superfamily member 10D ISO PID PID:200068 NCBI chr 8:21,242,378...21,300,551 JBrowse link
G LOC103232832 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO PID PID:200068 NCBI chr  X:128,781,975...128,816,039
Ensembl chr  X:128,787,785...128,806,083 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ISO PID PID:200068 NCBI chr16:11,366,610...11,485,411
Ensembl chr16:11,366,751...11,486,125 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200068 NCBI chr 4:53,040,731...53,120,784
Ensembl chr 4:53,084,023...53,120,772 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200068 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO PID PID:200068 NCBI chr 5:26,536,471...26,545,666
Ensembl chr 5:26,536,532...26,546,461 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO PID PID:200068 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200068 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO PID PID:200068 NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO PID PID:200068 NCBI chr20:122,040,131...122,111,397
Ensembl chr20:122,041,963...122,078,504 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200068 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 ISO PID PID:200068 NCBI chr 6:16,620,673...16,637,511
Ensembl chr 6:16,621,606...16,636,937 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 ISO PID PID:200068 NCBI chr20:86,651,692...86,748,670
Ensembl chr20:86,651,520...86,745,116 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 ISO PID PID:200068 NCBI chr17:69,065,509...69,117,825
Ensembl chr17:69,063,047...69,105,348 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 ISO PID PID:200068 NCBI chr 1:58,431,677...58,436,233
Ensembl chr 1:58,432,068...58,436,236 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO PID
RGD		 PMID:17403612 PMID:19934367 PMID:19961901 PID:200068 RGD:4142856 RGD:4143170 RGD:4143171 NCBI chr 8:21,318,987...21,351,641
Ensembl chr 8:21,315,149...21,351,673 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b ISO RGD
PID		 PMID:17403612 PMID:19961901 PID:200068 RGD:4143170 RGD:4143171 NCBI chr 8:21,101,945...21,150,362
Ensembl chr 8:21,102,267...21,150,267 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO RGD
PID		 PMID:17403612 PMID:19385008 PMID:19961901 PID:200068 RGD:2312745 RGD:4143170 RGD:4143171 NCBI chr15:16,934,982...16,953,155
Ensembl chr15:16,934,962...16,954,860 		JBrowse link
G TRADD TNFRSF1A associated via death domain ISO PID PID:200068 NCBI chr 5:60,296,777...60,303,076
Ensembl chr 5:60,297,375...60,303,579 		JBrowse link
G TRAF2 TNF receptor associated factor 2 ISO PID PID:200068 NCBI chr12:1,263,688...1,309,626
Ensembl chr12:1,263,274...1,290,907 		JBrowse link
tumor necrosis factor mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO PID
RGD		 PMID:12655295 PID:200102 RGD:2292150 NCBI chr14:98,092,093...98,157,657
Ensembl chr14:98,092,044...98,157,217 		JBrowse link
G BAG4 BAG cochaperone 4 ISO PID
RGD		 PMID:12655295 PID:200102 RGD:2292150 NCBI chr 8:36,198,547...36,231,550
Ensembl chr 8:36,198,811...36,231,828 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 ISO RGD
PID		 PMID:23085193 PID:200102 RGD:7800730 NCBI chr 1:93,721,449...93,746,638 JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ISO RGD
PID		 PMID:23085193 PID:200102 RGD:7800730 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G CASP8 caspase 8 ISO PID PID:200102 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G CAV1 caveolin 1 ISO PID PID:200102 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO PID
RGD		 PMID:12655295 PID:200102 RGD:2292150 NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase ISO PID
RGD		 PMID:21119682 PMID:23312890 PID:200102 RGD:7800734 RGD:7800735 NCBI chr 5:36,541,022...36,600,874
Ensembl chr 5:36,541,764...36,595,417 		JBrowse link
G FADD Fas associated via death domain ISO PID
RGD		 PMID:12655295 PID:200102 RGD:2292150 NCBI chr 1:4,358,314...4,361,863 JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO PID
RGD		 PMID:12655295 PID:200102 RGD:2292150 NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase ISO RGD PMID:21119682 PMID:23312890 RGD:7800734 RGD:7800735 NCBI chr 2:38,671,170...38,808,621
Ensembl chr 2:38,701,396...38,805,005 		JBrowse link
G LOC103232832 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chr  X:128,781,975...128,816,039
Ensembl chr  X:128,787,785...128,806,083 		JBrowse link
G MADD MAP kinase activating death domain ISO PID PID:200102 NCBI chr 1:17,987,573...18,041,317
Ensembl chr 1:17,986,860...18,042,266 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 ISO PID PID:200102 NCBI chr16:19,396,377...19,427,617
Ensembl chr16:19,396,452...19,427,652 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO PID PID:200102 NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200102 NCBI chr 4:53,040,731...53,120,784
Ensembl chr 4:53,084,023...53,120,772 		JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 ISO PID PID:200102 NCBI chr16:57,594,770...57,670,047
Ensembl chr16:57,597,288...57,669,720 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO PID PID:200102 NCBI chr13:36,614,489...36,858,524
Ensembl chr13:36,615,633...36,858,601 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO RGD
PID		 PMID:21135871 PID:200102 RGD:5490225 NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832 		JBrowse link
G MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 ISO PID PID:200102 NCBI chr 1:9,437,953...9,449,539
Ensembl chr 1:9,437,962...9,451,818 		JBrowse link
G MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 ISO PID PID:200102 NCBI chr14:67,931,906...68,121,640
Ensembl chr14:67,931,940...68,122,556 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 ISO PID PID:200102 NCBI chr14:5,391,416...5,579,163
Ensembl chr14:5,391,449...5,583,916 		JBrowse link
G MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 ISO PID PID:200102 NCBI chr24:27,496,269...27,604,726
Ensembl chr24:27,493,322...27,604,295 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 ISO PID PID:200102 NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498 		JBrowse link
G NRK Nik related kinase ISO PID PID:200102 NCBI chr  X:93,688,895...93,822,776
Ensembl chr  X:93,689,023...93,825,346 		JBrowse link
G NSMAF neutral sphingomyelinase activation associated factor ISO PID PID:200102 NCBI chr 8:54,565,714...54,642,896
Ensembl chr 8:54,567,121...54,642,054 		JBrowse link
G PRKCI protein kinase C iota ISO PID PID:200102 NCBI chr15:19,103,682...19,180,689 JBrowse link
G PRKCZ protein kinase C zeta ISO PID PID:200102 NCBI chr20:129,367,309...129,502,681
Ensembl chr20:129,365,679...129,485,818 		JBrowse link
G RACK1 receptor for activated C kinase 1 ISO PID PID:200102 NCBI chr23:82,800,211...82,805,769
Ensembl chr23:82,798,085...82,805,936 		JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 ISO RGD PMID:23085193 RGD:7800730 NCBI chr 2:35,537,387...35,559,628
Ensembl chr 2:35,538,127...35,560,129
Ensembl chr 2:35,538,127...35,560,129 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO PID PID:200102 NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase ISO PID PID:200102 NCBI chr16:28,515,393...28,593,289
Ensembl chr16:28,518,231...28,533,070 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 ISO PID
RGD		 PMID:12655295 PMID:23085193 PID:200102 RGD:2292150 RGD:7800730 NCBI chr17:69,065,509...69,117,825
Ensembl chr17:69,063,047...69,105,348 		JBrowse link
G RNF11 ring finger protein 11 ISO RGD PMID:21119682 PMID:23312890 RGD:7800734 RGD:7800735 NCBI chr20:81,681,975...81,718,622
Ensembl chr20:81,681,096...81,718,573 		JBrowse link
G RNF31 ring finger protein 31 ISO RGD PMID:23085193 RGD:7800730 NCBI chr24:1,133,589...1,146,020
Ensembl chr24:1,133,723...1,142,943 		JBrowse link
G SHARPIN SHANK associated RH domain interactor ISO RGD PMID:23085193 RGD:7800730 NCBI chr 8:138,310,036...138,315,120
Ensembl chr 8:138,307,581...138,315,101 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 ISO PID PID:200102 NCBI chr 1:58,431,677...58,436,233
Ensembl chr 1:58,432,068...58,436,236 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 ISO PID PID:200102 NCBI chr13:64,424,236...64,427,435
Ensembl chr13:64,424,250...64,427,366 		JBrowse link
G SQSTM1 sequestosome 1 ISO PID PID:200102 NCBI chr23:81,536,271...81,571,061
Ensembl chr23:81,558,082...81,574,830 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO PID PID:200102 NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO RGD
PID		 PMID:21135871 PID:200102 RGD:5490225 NCBI chr19:21,971,362...22,004,289 JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 ISO RGD
PID		 PMID:21135871 PID:200102 RGD:5490225 NCBI chr13:22,234,736...22,312,985
Ensembl chr13:22,234,012...22,282,562 		JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 ISO RGD PMID:21135871 RGD:5490225 NCBI chr  X:29,256,176...29,318,129
Ensembl chr  X:29,256,104...29,288,960 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 ISO RGD PMID:21119682 PMID:23312890 RGD:7800734 RGD:7800735 NCBI chr21:30,539,867...30,629,372
Ensembl chr21:30,540,791...30,629,345 		JBrowse link
G TNF tumor necrosis factor ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150
G TNFAIP3 TNF alpha induced protein 3 ISO RGD
PID		 PMID:21119682 PMID:23312890 PID:200102 RGD:7800734 RGD:7800735 NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO RGD
PID		 PMID:12655295 PMID:20967881 PID:200102 RGD:2292150 RGD:5130945 NCBI chr11:6,364,544...6,378,880
Ensembl chr11:6,364,330...6,378,902 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO RGD
PID		 PMID:12655295 PID:200102 RGD:2292150 NCBI chr20:119,590,621...119,633,562
Ensembl chr20:119,590,325...119,633,497 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase ISO PID PID:200102 NCBI chr15:18,011,137...18,403,676
Ensembl chr15:18,011,170...18,399,981 		JBrowse link
G TRADD TNFRSF1A associated via death domain ISO PID
RGD		 PMID:12655295 PID:200102 RGD:2292150 NCBI chr 5:60,296,777...60,303,076
Ensembl chr 5:60,297,375...60,303,579 		JBrowse link
G TRAF1 TNF receptor associated factor 1 ISO PID PID:200102 NCBI chr12:18,647,131...18,672,685
Ensembl chr12:18,650,190...18,670,643 		JBrowse link
G TRAF2 TNF receptor associated factor 2 ISO PID
RGD		 PMID:12655295 PMID:20967881 PMID:23085193 PID:200102 RGD:2292150 RGD:5130945 RGD:7800730 NCBI chr12:1,263,688...1,309,626
Ensembl chr12:1,263,274...1,290,907 		JBrowse link
G TRAF5 TNF receptor associated factor 5 ISO RGD PMID:23085193 RGD:7800730 NCBI chr25:18,124,720...18,173,601
Ensembl chr25:18,126,973...18,152,172 		JBrowse link
G TXN thioredoxin ISO PID PID:200102 NCBI chr12:29,296,166...29,308,979 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4056
    regulatory pathway 2500
      cell death pathway 185
        altered cell death pathway + 2
        non-programmed cell death pathway + 0
        programmed cell death pathway + 185
paths to the root