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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:retinol metabolic pathway
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Accession:PW:0000141 term browser browse the term
Definition:Those reactions involving retinol, a fat-soluble vitamin that is the dietary form of vitamin A and is important for bone growth and in vision. Precursors of retinol such as carotenoid or retinyl esters are derived from diet and are converted to retinal and retinol, respectively.
Synonyms:related_synonym: Retinoid metabolism and transport;   retinol metabolic process
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retinol metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO RGD PMID:21718801 RGD:6484679 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide IEA KEGG rno:00830 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879 		JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide IEA KEGG rno:00830 NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232 		JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) IEA KEGG rno:00830 NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:229,576,636...229,607,914 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide IEA KEGG rno:00830 NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:229,421,252...229,436,691 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 IDA
ISO 		RGD PMID:20709016 PMID:16970545 RGD:6903952, RGD:6903957 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 ISO SMPDB SMP:00074 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 IDA
IEA
ISO 		KEGG
SMPDB
RGD		 PMID:12547725 SMP:00074 rno:00830, RGD:1576367 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883 		JBrowse link
G Awat1 acyl-CoA wax alcohol acyltransferase 1 ISO SMPDB SMP:00074 NCBI chr  X:69,708,286...69,714,531
Ensembl chr  X:69,708,286...69,714,531 		JBrowse link
G Awat2 acyl-CoA wax alcohol acyltransferase 2 IEA KEGG rno:00830 NCBI chr  X:69,521,778...69,530,664
Ensembl chr  X:69,521,778...69,530,664 		JBrowse link
G Bco1 beta-carotene oxygenase 1 ISO
TAS
IEA 		KEGG
SMPDB
RGD		 PMID:21569862 PMID:21718801 SMP:00074 rno:00830, RGD:6903956, RGD:6484679 NCBI chr19:62,058,061...62,094,923
Ensembl chr19:62,058,089...62,094,917 		JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:21718801 RGD:6484679 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEA KEGG rno:00830 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEA KEGG rno:00830 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 IEA KEGG rno:00830 NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:118,599,356...118,616,176 		JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 IEA KEGG rno:00830 NCBI chr 1:244,870,412...244,881,610
Ensembl chr 1:244,871,612...244,880,297 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 IEA KEGG rno:00830 NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730 		JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 IEA KEGG rno:00830 NCBI chr 1:91,391,492...91,417,158
Ensembl chr 1:91,391,502...91,417,158 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IEA KEGG rno:00830 NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 IEA KEGG rno:00830 NCBI chr 1:91,135,294...91,147,094
Ensembl chr 1:91,135,294...91,208,159 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 IEA KEGG rno:00830 NCBI chr 1:90,722,243...90,736,272 JBrowse link
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 IEA KEGG rno:00830 NCBI chr 1:91,013,781...91,042,752
Ensembl chr 1:91,013,782...91,042,752 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 IEA KEGG rno:00830 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 IEA KEGG rno:00830 NCBI chr 1:248,619,887...248,681,945
Ensembl chr 1:248,619,882...248,677,042 		JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 IEA KEGG rno:00830 NCBI chr 1:248,706,787...248,787,239
Ensembl chr 1:248,706,788...248,787,210 		JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 IEA KEGG rno:00830 NCBI chr 1:248,941,143...248,980,767
Ensembl chr 1:248,904,062...248,971,182 		JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 IEA KEGG rno:00830 NCBI chr 1:252,838,427...252,863,081
Ensembl chr 1:252,838,433...252,863,067 		JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 IEA KEGG rno:00830 NCBI chr 1:247,966,295...248,022,393
Ensembl chr 1:247,966,346...248,022,388 		JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 IEA KEGG rno:00830 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IEA KEGG rno:00830 NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 IEA KEGG rno:00830 NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231 		JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 IEA KEGG rno:00830 NCBI chr 5:134,160,356...134,170,908
Ensembl chr 5:134,160,358...134,176,156 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 IEA KEGG rno:00830 NCBI chr 5:134,334,396...134,352,268
Ensembl chr 5:134,334,701...134,352,236 		JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 IEA KEGG rno:00830 NCBI chr 5:133,938,882...133,970,226
Ensembl chr 5:133,938,883...133,970,226 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:162,031,386...162,065,653 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 3:74,553,357...74,579,535
Ensembl chr 3:74,555,606...74,581,376 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00074 NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00074 NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 ISO SMPDB SMP:00074 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO SMPDB SMP:00074 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hyou1 hypoxia up-regulated 1 ISO SMPDB SMP:00074 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997 		JBrowse link
G Lrat lecithin retinol acyltransferase TAS
IEA
ISO 		KEGG
SMPDB
RGD		 PMID:21718801 SMP:00074 rno:00830, RGD:6484679 NCBI chr 2:170,562,148...170,571,212
Ensembl chr 2:170,565,543...170,571,148 		JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 ISO SMPDB SMP:00074 NCBI chr10:15,720,301...15,723,386
Ensembl chr10:15,720,301...15,723,396 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 ISO SMPDB SMP:00074 NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 ISO SMPDB SMP:00074 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091 		JBrowse link
G Plb1 phospholipase B1 IDA
TAS 		RGD PMID:8117729 PMID:21718801 RGD:6903951, RGD:6484679 NCBI chr 6:29,807,127...29,945,607
Ensembl chr 6:29,809,290...29,930,183 		JBrowse link
G Pnlip pancreatic lipase TAS RGD PMID:21718801 RGD:6484679 NCBI chr 1:267,760,073...267,797,797
Ensembl chr 1:267,784,724...267,797,795 		JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 ISO RGD PMID:21718801 RGD:6484679 NCBI chr 1:267,883,906...267,902,572
Ensembl chr 1:267,883,906...267,902,572 		JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr  X:46,200,351...46,205,517
Ensembl chr  X:46,193,332...46,205,089 		JBrowse link
G Ppib peptidylprolyl isomerase B ISO SMPDB SMP:00074 NCBI chr 8:75,498,966...75,504,823
Ensembl chr 8:75,498,797...75,504,847 		JBrowse link
G Rbp2 retinol binding protein 2 ISO RGD PMID:21718801 RGD:6484679 NCBI chr 8:107,958,670...107,983,850 JBrowse link
G Rdh10 retinol dehydrogenase 10 IEA KEGG rno:00830 NCBI chr 5:7,969,931...7,998,834
Ensembl chr 5:7,971,705...7,999,019 		JBrowse link
G Rdh11 retinol dehydrogenase 11 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 6:103,712,373...103,728,247
Ensembl chr 6:103,712,374...103,729,741 		JBrowse link
G Rdh12 retinol dehydrogenase 12 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 6:103,748,457...103,761,379
Ensembl chr 6:103,748,427...103,761,380 		JBrowse link
G Rdh16 retinol dehydrogenase 16 ISO SMPDB SMP:00074 NCBI chr 7:65,499,763...65,510,304 JBrowse link
G Rdh5 retinol dehydrogenase 5 IEA KEGG rno:00830 NCBI chr 7:1,912,120...1,931,836
Ensembl chr 7:1,925,335...1,936,049 		JBrowse link
G Rdh7 retinol dehydrogenase 7 IEA KEGG rno:00830 NCBI chr 7:65,561,259...65,574,618
Ensembl chr 7:65,560,822...65,574,635 		JBrowse link
G Rdh8 retinol dehydrogenase 8 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 8:27,629,380...27,636,651
Ensembl chr 8:27,629,380...27,636,651 		JBrowse link
G Retsat retinol saturase IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:106,211,436...106,229,552 		JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 2:251,425,228...251,457,209
Ensembl chr 2:251,425,368...251,457,156 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO RGD PMID:21718801 RGD:6484679 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 ISO SMPDB SMP:00074 NCBI chr11:97,376,878...97,379,120
Ensembl chr11:97,376,878...97,379,120 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IEA
ISO 		KEGG
SMPDB		 SMP:00074 rno:00830 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 IEA KEGG rno:00830 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 IEA KEGG rno:00830 NCBI chr 9:96,228,134...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 IEA KEGG rno:00830 NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a6a UDP glucuronosyltransferase family 1 member A6a IEA KEGG rno:00830 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C IEA KEGG rno:00830 NCBI chr 9:96,187,382...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 IEA KEGG rno:00830 NCBI chr 9:96,174,899...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 IEA KEGG rno:00830 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 IEA KEGG rno:00830 NCBI chr14:20,797,262...20,825,111
Ensembl chr14:20,800,263...20,825,111 		JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 IEA KEGG rno:00830 NCBI chr14:20,851,970...20,869,974
Ensembl chr14:20,851,969...20,869,973 		JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B IEA KEGG rno:00830 NCBI chr14:20,985,449...21,006,267
Ensembl chr14:20,985,108...21,020,850 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IEA KEGG rno:00830 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331 		JBrowse link
G Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37 IEA KEGG rno:00830 NCBI chr14:21,172,136...21,188,768
Ensembl chr14:21,172,133...21,190,661 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6090
    classic metabolic pathway 1853
      metabolic pathway pertinent to the brain 131
        retinoid metabolic pathway 97
          retinol metabolic pathway 82
Path 2
Term Annotations click to browse term
  pathway 6090
    regulatory pathway 3864
      homeostasis pathway 1772
        organic chemical homeostasis pathway 767
          vitamin homeostasis 151
            vitamin A homeostasis 151
              retinoid metabolic pathway 97
                retinol metabolic pathway 82
paths to the root