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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:lysine degradation pathway
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Accession:PW:0000073 term browser browse the term
Definition:Those metabolic reactions involved in the degradation of lysine. In mammals, lysine is metabolized to acetyl-CoA. A derivative of lysine, allysine, is used in the production of elastin and collagen.
Synonyms:related_synonym: Lysine catabolism;   lysine catabolic process


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lysine degradation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr16:34,520,236...34,566,388
Ensembl chr16:34,520,238...34,566,540 		JBrowse link
G Aass aminoadipate-semialdehyde synthase IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:52,572,147...52,657,600 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 IEA KEGG rno:00310 NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IEA KEGG rno:00310 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 IEA KEGG rno:00310 NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 IEA KEGG rno:00310 NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEA KEGG rno:00310 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 IEA KEGG rno:00310 NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 IEA KEGG rno:00310 NCBI chr13:82,038,679...82,055,478
Ensembl chr13:82,038,533...82,055,481 		JBrowse link
G Arxes1 adipocyte-related X-chromosome expressed sequence 1 IEA KEGG rno:00310 NCBI chr  X:103,742,157...103,743,676 JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase IEA KEGG rno:00310 NCBI chr 2:176,644,393...176,780,848
Ensembl chr 2:176,644,924...176,780,847 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 IEA KEGG rno:00310 NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064 		JBrowse link
G Colgalt1 collagen beta(1-O)galactosyltransferase 1 IEA KEGG rno:00310 NCBI chr16:18,353,779...18,366,087
Ensembl chr16:18,353,570...18,366,086 		JBrowse link
G Colgalt2 collagen beta(1-O)galactosyltransferase 2 IEA KEGG rno:00310 NCBI chr13:67,073,551...67,178,194
Ensembl chr13:67,073,551...67,178,194 		JBrowse link
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 ISO SMPDB SMP:00037 NCBI chr17:77,242,512...77,316,074
Ensembl chr17:77,264,514...77,316,071 		JBrowse link
G Dld dihydrolipoamide dehydrogenase ISO SMPDB SMP:00037 NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:53,619,631...53,652,354 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr 6:110,489,576...110,512,841
Ensembl chr 6:110,489,392...110,514,357 		JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase IEA KEGG rno:00310 NCBI chr 7:9,569,439...9,607,095
Ensembl chr 7:9,569,439...9,607,095 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase IEA KEGG rno:00310 NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662 		JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 IEA KEGG rno:00310 NCBI chr 3:27,978,888...28,127,178
Ensembl chr 3:27,978,888...28,127,349 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 IEA KEGG rno:00310 NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,924,263...3,941,384 		JBrowse link
G Gcdh glutaryl-CoA dehydrogenase IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr19:40,168,038...40,174,536
Ensembl chr19:40,168,141...40,175,686 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha IEA KEGG rno:00310 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Kmt2d lysine methyltransferase 2D IEA KEGG rno:00310 NCBI chr 7:131,859,696...131,901,032
Ensembl chr 7:131,859,696...131,900,072 		JBrowse link
G Kmt2e lysine methyltransferase 2E IEA KEGG rno:00310 NCBI chr 4:12,550,570...12,655,329
Ensembl chr 4:12,550,570...12,619,721 		JBrowse link
G Kmt5a lysine methyltransferase 5A IEA KEGG rno:00310 NCBI chr12:37,800,339...37,823,706
Ensembl chr12:37,800,344...37,823,783 		JBrowse link
G Kmt5al2 lysine methyltransferase 5A like 2 IEA KEGG rno:00310 NCBI chr  X:96,451,051...96,454,623 JBrowse link
G Kmt5al3 lysine methyltransferase 5A like 3 IEA KEGG rno:00310 NCBI chr11:16,925,044...16,927,264 JBrowse link
G Kmt5b lysine methyltransferase 5B IEA KEGG rno:00310 NCBI chr 1:210,429,672...210,479,042
Ensembl chr 1:210,430,127...210,479,035 		JBrowse link
G Kmt5c lysine methyltransferase 5C IEA KEGG rno:00310 NCBI chr 1:78,128,325...78,135,931
Ensembl chr 1:78,128,325...78,135,931 		JBrowse link
G Nsd1 nuclear receptor binding SET domain protein 1 IEA KEGG rno:00310 NCBI chr17:9,317,085...9,431,528
Ensembl chr17:9,317,085...9,452,250 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 IEA KEGG rno:00310 NCBI chr14:81,057,727...81,135,866
Ensembl chr14:81,057,727...81,123,027 		JBrowse link
G Nsd3 nuclear receptor binding SET domain protein 3 IEA KEGG rno:00310 NCBI chr16:73,056,748...73,170,082
Ensembl chr16:73,061,694...73,168,130 		JBrowse link
G Ogdh oxoglutarate dehydrogenase IEA KEGG rno:00310 NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271 		JBrowse link
G Ogdhl oxoglutarate dehydrogenase L IEA KEGG rno:00310 NCBI chr16:7,584,666...7,610,705
Ensembl chr16:7,584,657...7,610,698 		JBrowse link
G Pipox pipecolic acid and sarcosine oxidase IEA
ISO 		KEGG
SMPDB		 SMP:00037 rno:00310 NCBI chr10:63,267,946...63,281,556
Ensembl chr10:63,267,972...63,282,273 		JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 IEA KEGG rno:00310 NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 IEA KEGG rno:00310 NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 IEA KEGG rno:00310 NCBI chr12:25,313,070...25,323,631
Ensembl chr12:25,313,072...25,323,631 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase IEA KEGG rno:00310 NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:119,390,207...119,475,863 		JBrowse link
G Setd7 SET domain containing 7, histone lysine methyltransferase IEA KEGG rno:00310 NCBI chr 2:137,713,545...137,756,319
Ensembl chr 2:137,713,545...137,756,319 		JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 IEA KEGG rno:00310 NCBI chr 2:185,587,722...185,619,084
Ensembl chr 2:185,587,722...185,618,982 		JBrowse link
G Setmar SET domain and mariner transposase fusion gene IEA KEGG rno:00310 NCBI chr 4:142,602,066...142,614,208
Ensembl chr 4:142,602,088...142,614,206 		JBrowse link
G Slc25a2 solute carrier family 25 member 2 ISO SMPDB SMP:00037 NCBI chr18:29,704,182...29,707,563
Ensembl chr18:29,703,871...29,708,827 		JBrowse link
G Slc7a2 solute carrier family 7 member 2 ISO SMPDB SMP:00037 NCBI chr16:58,115,991...58,174,256
Ensembl chr16:58,120,968...58,174,256 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase IEA KEGG rno:00310 NCBI chr  X:17,093,059...17,105,942
Ensembl chr  X:17,092,986...17,105,942 		JBrowse link
G Suv39h2 SUV39H2 histone lysine methyltransferase IEA KEGG rno:00310 NCBI chr17:79,665,467...79,684,492
Ensembl chr17:79,665,376...79,684,492 		JBrowse link
G Tmlhe trimethyllysine hydroxylase, epsilon IEA KEGG rno:00310 NCBI chr20:96,561...144,414
Ensembl chr20:107,516...144,543 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      amino acid metabolic pathway 308
        amino acid metabolic pathway (KEGG) 266
          lysine degradation pathway 52
paths to the root