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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:valine, leucine and isoleucine degradation pathway
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Accession:PW:0000071 term browser browse the term
Definition:Those metabolic reactions involved in the degradation of valine, leucine and isoleucine - the three dietary-essential branched amino acids.
Synonyms:related_synonym: Branched-chain amino acid catabolism;   branched-chain amino acid catabolic process


show annotations for term's descendants           Sort by:
valine, leucine and isoleucine degradation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A IEA KEGG rno:00280 NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B IEA KEGG rno:00280 NCBI chr 8:127,750,771...127,759,589
Ensembl chr 8:127,750,743...127,759,569 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420 		JBrowse link
G Acad8 acyl-CoA dehydrogenase family, member 8 ISO SMPDB SMP:00032 NCBI chr 8:25,382,271...25,406,404
Ensembl chr 8:33,641,420...33,665,542 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr12:47,154,259...47,163,580
Ensembl chr12:47,154,276...47,164,103 		JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 1:195,619,088...195,660,564
Ensembl chr 1:195,619,038...195,660,561 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 IEA KEGG rno:00280 NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IEA KEGG rno:00280 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 IEA KEGG rno:00280 NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 IEA KEGG rno:00280 NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 IEA KEGG rno:00280 NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:109,809,122...109,829,743 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 IEA KEGG rno:00280 NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 IEA KEGG rno:00280 NCBI chr13:82,038,679...82,055,478
Ensembl chr13:82,038,533...82,055,481 		JBrowse link
G Aox1 aldehyde oxidase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980 		JBrowse link
G Aox2 aldehyde oxidase 2 IEA KEGG rno:00280 NCBI chr 9:67,322,291...67,411,694
Ensembl chr 9:67,322,598...67,410,363 		JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr17:12,481,396...12,576,748
Ensembl chr17:12,481,416...12,602,587 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 IEA
IDA 		KEGG
RGD		 PMID:11733007 rno:00280, RGD:1582175 NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 1:90,266,731...90,295,521
Ensembl chr 1:90,261,629...90,295,749 		JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:93,725,275...93,907,798 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525 		JBrowse link
G Dld dihydrolipoamide dehydrogenase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:53,619,631...53,652,354 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase IEA KEGG rno:00280 NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEA KEGG rno:00280 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha IEA KEGG rno:00280 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta IEA KEGG rno:00280 NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835 		JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:82,979,765...83,111,242 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886 		JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 5:153,461,738...153,475,552
Ensembl chr 5:153,461,769...153,475,604 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IEA KEGG rno:00280 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr  X:24,568,551...24,571,012
Ensembl chr  X:24,568,551...24,574,681 		JBrowse link
G Ivd isovaleryl-CoA dehydrogenase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 3:126,305,584...126,326,016
Ensembl chr 3:126,305,364...126,328,160 		JBrowse link
G Lao1 L-amino acid oxidase 1 IEA KEGG rno:00280 NCBI chr 5:137,859,033...137,868,926
Ensembl chr 5:137,859,033...137,868,917 		JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:120,727,313...120,779,334
Ensembl chr 2:120,727,316...120,779,554 		JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:33,039,044...33,110,092
Ensembl chr 2:33,039,045...33,110,299 		JBrowse link
G Mcee methylmalonyl CoA epimerase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:127,376,298...127,400,367 		JBrowse link
G Mmut methylmalonyl-CoA mutase IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342 		JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:54,963,964...55,112,303
Ensembl chr 2:54,963,784...55,112,298 		JBrowse link
G Oxct2a 3-oxoacid CoA transferase 2A IEA KEGG rno:00280 NCBI chr 5:140,885,914...140,887,672
Ensembl chr 5:140,874,503...140,902,881 		JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr15:106,034,586...106,374,908
Ensembl chr15:106,034,610...106,374,908 		JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta IEA
ISO 		KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 8:110,470,197...110,520,222
Ensembl chr 8:110,469,934...110,520,187 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      amino acid metabolic pathway 308
        amino acid metabolic pathway (KEGG) 266
          valine, leucine and isoleucine degradation pathway 48
paths to the root