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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:signaling pathway pertinent to the brain and nervous system
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Accession:PW:0000059 term browser browse the term
Definition:Those signaling pathways that are involved in or mediate the various aspects of nervous system and/or brain function.


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signaling pathway pertinent to the brain and nervous system term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16600505 RGD:1581409 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase (Cartwright blood group) ISO RGD PMID:17786266 RGD:8549506 NCBI chrNW_004936543:856,678...862,080 JBrowse link
G Chat choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936728:653,654...702,433 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936599:2,437,061...2,456,141 JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:19478075 RGD:8549592 NCBI chrNW_004936486:8,720,036...8,830,472 JBrowse link
G Rgs2 regulator of G protein signaling 2 ISO RGD PMID:22685433 RGD:8549594 NCBI chrNW_004936638:1,065,866...1,068,649 JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:22685433 RGD:8549594 NCBI chrNW_004937238:101,948...109,513 JBrowse link
G Rgs6 regulator of G protein signaling 6 ISO RGD PMID:22685433 RGD:8549594 NCBI chrNW_004936488:1,336,075...1,924,635 JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936728:703,688...706,317 JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936729:1,511,648...1,534,042 JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm2 cholinergic receptor muscarinic 2 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936592:1,396,939...1,525,255 JBrowse link
G Chrm4 cholinergic receptor muscarinic 4 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936562:2,685,209...2,687,751 JBrowse link
G Gnai1 G protein subunit alpha i1 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936810:353,405...435,087 JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936529:1,779,582...1,801,251 JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor muscarinic 1 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936581:387,939...400,740 JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936484:13,953,141...14,373,174 JBrowse link
G Chrm5 cholinergic receptor muscarinic 5 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936673:2,607,906...2,610,885 JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936588:1,770,777...1,789,143 JBrowse link
G Gna14 G protein subunit alpha 14 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936503:12,860,296...13,056,880 JBrowse link
G Gnaq G protein subunit alpha q ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936503:13,098,517...13,276,106 JBrowse link
acetylcholine signaling pathway via nicotinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase (Cartwright blood group) ISO RGD PMID:17786266 RGD:8549506 NCBI chrNW_004936543:856,678...862,080 JBrowse link
G Agrn agrin ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936737:2,010,647...2,041,401 JBrowse link
G Chat choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936728:653,654...702,433 JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chrNW_004936509:4,452,382...4,470,658 JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936498:1,224,123...1,230,640 JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936675:327,501...334,493 JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936471:36,427,598...36,447,903 JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936514:10,680,893...10,695,859 JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936471:36,451,070...36,492,774 JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936785:17,588...28,565 JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936482:7,792,292...7,801,152 JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chrNW_004936595:727,907...735,783 JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936580:4,165,255...4,179,285 JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936785:46,076...72,529 JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936471:36,408,471...36,425,571 JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chrNW_004936525:4,560,293...4,568,431 JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chrNW_004936677:2,809,057...2,813,838 JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chrNW_004936525:4,550,987...4,556,574 JBrowse link
G Dok7 docking protein 7 ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936477:20,251,154...20,278,476 JBrowse link
G Lrp4 LDL receptor related protein 4 ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936562:2,211,519...2,262,899 JBrowse link
G Musk muscle associated receptor tyrosine kinase ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936559:2,387,019...2,486,685 JBrowse link
G Rapsn receptor associated protein of the synapse ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936562:1,796,087...1,804,153 JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936728:703,688...706,317 JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936729:1,511,648...1,534,042 JBrowse link
altered clathrin-dependent synaptic vesicle endocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 ISO RGD PMID:25302295 RGD:10450553 NCBI chrNW_004936692:2,788,477...2,836,094 JBrowse link
G Synj1 synaptojanin 1 ISO RGD PMID:25302295 RGD:10450553 NCBI chrNW_004936500:9,484,571...9,565,980 JBrowse link
altered Reelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab1 DAB adaptor protein 1 ISO RGD PMID:12670697, PMID:12764038, PMID:16266828 RGD:1358468, RGD:2324967, RGD:727518 NCBI chrNW_004936522:3,498,395...4,612,560 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:12778121 RGD:2324970 NCBI chrNW_004936679:388,500...588,518 JBrowse link
G Itga3 integrin subunit alpha 3 ISO RGD PMID:15583703 RGD:2325851 NCBI chrNW_004936490:11,553,904...11,583,387 JBrowse link
G Itgb1 integrin subunit beta 1 ISO RGD PMID:15583703 RGD:2325851 NCBI chrNW_004936574:1,465,981...1,495,717 JBrowse link
G Lrp8 LDL receptor related protein 8 ISO RGD PMID:19846452 RGD:2324974 NCBI chrNW_004936522:7,740,887...7,820,488 JBrowse link
G Pafah1b1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 ISO RGD PMID:17330141 RGD:4107040 NCBI chrNW_004936538:8,612,142...8,693,698 JBrowse link
G Pafah1b2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 ISO RGD PMID:17330141 RGD:4107040 NCBI chrNW_004936542:2,390,904...2,417,596 JBrowse link
G Pafah1b3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 ISO RGD PMID:17330141 RGD:4107040 NCBI chrNW_004936706:212,635...215,498 JBrowse link
G Reln reelin ISO RGD PMID:12670697, PMID:12764038 RGD:1358468, RGD:727518 NCBI chrNW_004936479:19,628,488...20,088,278 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:18237558 RGD:2325284 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Vldlr very low density lipoprotein receptor ISO RGD PMID:12764038 RGD:1358468 NCBI chrNW_004936503:2,407,040...2,440,366 JBrowse link
altered visual phototransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:20212494 RGD:8547536 NCBI chrNW_004936482:14,091,343...14,107,793 JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:20212494 RGD:8547536 NCBI chrNW_004936475:9,844,438...9,908,009 JBrowse link
G Guca1b guanylate cyclase activator 1B ISO RGD PMID:20212494 RGD:8547536 NCBI chrNW_004936476:17,679,505...17,688,970 JBrowse link
G Pde6a phosphodiesterase 6A ISO RGD PMID:20212494 RGD:8547536 NCBI chrNW_004936504:5,018,171...5,088,333 JBrowse link
G Pde6b phosphodiesterase 6B ISO RGD PMID:20212494 RGD:8547536 NCBI chrNW_004936477:22,418,037...22,472,251 JBrowse link
G Pde6g phosphodiesterase 6G ISO RGD PMID:20212494 RGD:8547536 NCBI chrNW_004936594:5,263,345...5,267,240 JBrowse link
G Rho rhodopsin ISO RGD PMID:20212494 RGD:8547536 NCBI chrNW_004936602:896,730...901,480 JBrowse link
G Sag S-antigen visual arrestin ISO RGD PMID:20212494 RGD:8547536 NCBI chrNW_004936525:3,932,118...3,965,651 JBrowse link
auditory mechanotransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin beta ISO RGD PMID:20624897 RGD:8547669 NCBI chrNW_004936765:667,107...670,627 JBrowse link
G Actg1 actin gamma 1 ISO RGD PMID:20624897 RGD:8547669 NCBI chrNW_004936594:5,170,711...5,173,251 JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 ISO RGD PMID:20624897 RGD:8547669 NCBI chrNW_004936469:8,653,031...9,209,840 JBrowse link
G Cdh23 cadherin related 23 ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chrNW_004936521:7,078,874...7,285,361 JBrowse link
G Espn espin ISO RGD PMID:19804752, PMID:20624897 RGD:8547667, RGD:8547669 NCBI chrNW_004936623:1,220,435...1,249,743 JBrowse link
G LOC101965031 protocadherin-15 ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chrNW_004936910:233,800...602,145 JBrowse link
G Myo15a myosin XVA ISO RGD PMID:19804752 RGD:8547667 NCBI chrNW_004936741:1,669,680...1,724,929 JBrowse link
G Myo1c myosin IC ISO RGD PMID:19804752 RGD:8547667 NCBI chrNW_004936538:7,614,985...7,639,603 JBrowse link
G Myo3a myosin IIIA ISO RGD PMID:19804752 RGD:8547667 NCBI chrNW_004936484:1,509,248...1,723,717 JBrowse link
G Myo6 myosin VI ISO RGD PMID:20624897, PMID:22715884 RGD:8547669, RGD:8547672 NCBI chrNW_004936788:1,125,332...1,264,372 JBrowse link
G Myo7a myosin VIIA ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chrNW_004936498:5,758,572...5,824,526 JBrowse link
G Otof otoferlin ISO RGD PMID:22715884 RGD:8547672 NCBI chrNW_004936493:5,916,113...5,999,867 JBrowse link
G Pls1 plastin 1 ISO RGD PMID:20624897 RGD:8547669 NCBI chrNW_004936540:4,205,871...4,323,121 JBrowse link
G Pls3 plastin 3 ISO RGD PMID:20624897 RGD:8547669 NCBI chrNW_004936499:246,042...335,440 JBrowse link
G Ptprq protein tyrosine phosphatase receptor type Q ISO RGD PMID:20624897 RGD:8547669 NCBI chrNW_004936698:1,372,604...1,569,905 JBrowse link
G Slc17a8 solute carrier family 17 member 8 ISO RGD PMID:22715884 RGD:8547672 NCBI chrNW_004936492:13,436,136...13,486,173 JBrowse link
G Ush1c USH1 protein network component harmonin ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chrNW_004936528:1,552,175...1,594,740 JBrowse link
G Ush1g USH1 protein network component sans ISO RGD PMID:22177415 RGD:8547671 NCBI chrNW_004936594:258,115...262,739 JBrowse link
G Ush2a usherin ISO RGD PMID:20624897 RGD:8547669 NCBI chrNW_004936628:2,123,917...2,859,958 JBrowse link
G Whrn whirlin ISO RGD PMID:19804752 RGD:8547667 NCBI chrNW_004936487:3,668,465...3,748,234 JBrowse link
brain-derived neurotrophic factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain derived neurotrophic factor ISO RGD PMID:23670594 RGD:11062158 NCBI chrNW_004936540:5,530,081...5,582,765 JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chrNW_004936545:7,286,018...7,407,623 JBrowse link
G Grb2 growth factor receptor bound protein 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chrNW_004936594:592,760...661,369 JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chrNW_004936680:267,850...621,467 JBrowse link
G Shc1 SHC adaptor protein 1 ISO RGD PMID:23670594 RGD:11062158 NCBI chrNW_004936580:4,511,560...4,522,003 JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 ISO RGD PMID:23670594 RGD:11062158 NCBI chrNW_004936500:10,451,599...10,812,239 JBrowse link
clathrin-dependent synaptic vesicle endocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936664:3,562,800...3,596,983 JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936888:689,673...735,119 JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936490:5,156...127,666 JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936578:5,680,748...5,691,666 JBrowse link
G Clta clathrin light chain A ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936524:4,170,425...4,191,951 JBrowse link
G Cltb clathrin light chain B ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936597:665,365...689,867 JBrowse link
G Cltc clathrin heavy chain ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936490:3,659,682...3,726,222 JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936692:2,788,477...2,836,094 JBrowse link
G Dnm1 dynamin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936487:15,767,897...15,797,722 JBrowse link
G Dnm3 dynamin 3 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936481:14,971,977...15,411,253 JBrowse link
G Dnmbp dynamin binding protein ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936636:212,572...279,815 JBrowse link
G Epn1 epsin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936981:194,176...213,021 JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936522:9,438,929...9,486,781 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936542:7,577,192...7,581,598 JBrowse link
G Itsn1 intersectin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936500:8,490,514...8,678,127 JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936588:2,070,873...2,088,144 JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936588:2,504,372...2,535,993 JBrowse link
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936483:18,051,023...18,176,514 JBrowse link
G Snap91 synaptosome associated protein 91 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936510:7,222,200...7,345,138 JBrowse link
G Synj1 synaptojanin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chrNW_004936500:9,484,571...9,565,980 JBrowse link
dopamine signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5 cyclin dependent kinase 5 ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936527:6,478,934...6,483,848 JBrowse link
G Csnk1a1 casein kinase 1 alpha 1 ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936504:5,351,354...5,394,856 JBrowse link
G Drd1 dopamine receptor D1 ISO heterodimer coupled to Galphaq RGD PMID:17314300, PMID:25671228 RGD:11041142, RGD:1625010 NCBI chrNW_004936609:790,647...795,187 JBrowse link
G Drd2 dopamine receptor D2 ISO heterodimer coupled to Galphaq RGD PMID:12121979, PMID:16490190, PMID:17314300, PMID:25671228 RGD:11041142, RGD:1581445, RGD:1625010, RGD:1625068 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Drd3 dopamine receptor D3 ISO RGD PMID:16490190 RGD:1625068 NCBI chrNW_004936536:1,580,732...1,616,726 JBrowse link
G Drd4 dopamine receptor D4 ISO RGD PMID:17314300 RGD:1625010 NCBI chrNW_004936888:468,334...471,254 JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:25671228 RGD:11041142 NCBI chrNW_004936477:16,860,222...16,863,505 JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936599:2,345,982...2,348,494 JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936493:3,981,364...4,002,083 JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936558:3,631,794...3,651,754 JBrowse link
G Ppp1r1b protein phosphatase 1 regulatory inhibitor subunit 1B ISO RGD PMID:21303898, PMID:21927600 RGD:11041134, RGD:11041163 NCBI chrNW_004936490:14,822,246...14,831,337 JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936647:1,031,118...1,055,961 JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936792:622,105...633,800 JBrowse link
G Ppp2r3a protein phosphatase 2 regulatory subunit B''alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936529:8,885,803...9,034,217 JBrowse link
G Ppp2r5d protein phosphatase 2 regulatory subunit B'delta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936476:16,922,204...16,945,400 JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936520:1,987,989...2,146,473 JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936521:5,576,705...5,614,738 JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936555:6,216,202...6,283,012 JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936659:2,750,015...2,765,914 JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936608:1,353,905...1,464,636 JBrowse link
G Ptpn5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936528:523,884...586,306 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16529858 RGD:1581410 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
dopamine signaling pathway via D1 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00308 NCBI chrNW_004936643:47,830...338,891 JBrowse link
G Adcy5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chrNW_004936725:1,751,272...1,897,937 JBrowse link
G Arrb1 arrestin beta 1 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936498:4,089,621...4,172,749 JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Drd1 dopamine receptor D1 ISO SMPDB
RGD
PMID:21303898 RGD:11041134, SMP:00308 NCBI chrNW_004936609:790,647...795,187 JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936477:16,860,222...16,863,505 JBrowse link
G Gnal G protein subunit alpha L ISO RGD PMID:24144882 RGD:11041135 NCBI chrNW_004936626:372,893...460,884 JBrowse link
G Gnas GNAS complex locus ISO SMPDB SMP:00308 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00308 NCBI chrNW_004936737:1,518,855...1,554,926 JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00308 NCBI chrNW_004936591:3,860,668...3,983,305 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936599:2,437,061...2,456,141 JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936657:425,902...522,331 JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936486:8,720,036...8,830,472 JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936597:1,706,671...1,722,370 JBrowse link
G LOC101958197 regulator of G protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936541:7,472,195...7,525,220 JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00308 NCBI chrNW_004936608:1,353,905...1,464,636 JBrowse link
G Rgs2 regulator of G protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936638:1,065,866...1,068,649 JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004937238:101,948...109,513 JBrowse link
G Rgs7 regulator of G protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936526:9,087,820...9,552,482 JBrowse link
G Rgs7bp regulator of G protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936480:4,466,355...4,565,322 JBrowse link
dopamine signaling pathway via D2 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chrNW_004936725:1,751,272...1,897,937 JBrowse link
G Arrb1 arrestin beta 1 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936498:4,089,621...4,172,749 JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Drd3 dopamine receptor D3 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936536:1,580,732...1,616,726 JBrowse link
G Drd4 dopamine receptor D4 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936888:468,334...471,254 JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:24831693 RGD:11041136 NCBI chrNW_004936529:1,779,582...1,801,251 JBrowse link
G Gnao1 G protein subunit alpha o1 ISO RGD PMID:24831693 RGD:11041136 NCBI chrNW_004936475:8,610,123...8,681,606 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898, PMID:23940634 RGD:11041134, RGD:13792715 NCBI chrNW_004936599:2,437,061...2,456,141 JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936657:425,902...522,331 JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936486:8,720,036...8,830,472 JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936597:1,706,671...1,722,370 JBrowse link
G LOC101958197 regulator of G protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936541:7,472,195...7,525,220 JBrowse link
G Rgs2 regulator of G protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936638:1,065,866...1,068,649 JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004937238:101,948...109,513 JBrowse link
G Rgs7 regulator of G protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936526:9,087,820...9,552,482 JBrowse link
G Rgs7bp regulator of G protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936480:4,466,355...4,565,322 JBrowse link
epinephrine signaling pathway via adrenergic receptor beta term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:19110970 RGD:4140391 NCBI chrNW_004936486:4,400,467...4,401,588 JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:19110970 RGD:4140391 NCBI chrNW_004936504:5,985,407...5,987,453 JBrowse link
G Arrb1 arrestin beta 1 ISO RGD PMID:18268361, PMID:19229505 RGD:4140419, RGD:5135529 NCBI chrNW_004936498:4,089,621...4,172,749 JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:18268361, PMID:19229505 RGD:4140419, RGD:5135529 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Gnas GNAS complex locus ISO RGD PMID:19110970 RGD:4140391 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:19110970, PMID:19229505 RGD:4140391, RGD:5135529 NCBI chrNW_004936599:2,437,061...2,456,141 JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:19110970, PMID:19229505 RGD:4140391, RGD:5135529 NCBI chrNW_004936486:8,720,036...8,830,472 JBrowse link
G Snx13 sorting nexin 13 ISO RGD PMID:17173929 RGD:4140388 NCBI chrNW_004936546:4,127,333...4,270,107 JBrowse link
excitatory synaptic transmission pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 ISO RGD PMID:17314300 RGD:1625010 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Drd4 dopamine receptor D4 ISO RGD PMID:17314300 RGD:1625010 NCBI chrNW_004936888:468,334...471,254 JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:16477151 RGD:1642190 NCBI chrNW_004936669:814,330...838,881 JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16477151 RGD:1642190 NCBI chrNW_004936530:8,286,101...8,612,183 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:16477151 RGD:1642190 NCBI chrNW_004936587:3,406,055...3,806,956 JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A ISO RGD PMID:16477151 RGD:1642190 NCBI chrNW_004936524:9,720,777...9,884,984 JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B ISO RGD PMID:11823786 RGD:632842 NCBI chrNW_004936588:433,544...440,534 JBrowse link
G Kcnd1 potassium voltage-gated channel subfamily D member 1 ISO RGD PMID:16141270 RGD:1581430 NCBI chrNW_004936721:881,162...890,939 JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 ISO RGD PMID:16141270 RGD:1581430 NCBI chrNW_004936605:4,370,222...4,828,972 JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 ISO RGD PMID:16141270 RGD:1581430 NCBI chrNW_004936690:417,907...627,025 JBrowse link
Inhibitory synaptic transmission pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glra1 glycine receptor alpha 1 ISO RGD PMID:14749434 RGD:1598573 NCBI chrNW_004936515:10,816,712...10,896,958 JBrowse link
G Glrb glycine receptor beta ISO RGD PMID:14749434 RGD:1598573 NCBI chrNW_004936576:3,665,128...3,752,592 JBrowse link
G Gphn gephyrin ISO RGD PMID:14976213 RGD:1300220 NCBI chrNW_004936495:9,970,683...10,565,467 JBrowse link
kallikrein-kinin cascade pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936870:424,832...468,303 JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936604:551,774...567,014 JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936604:548,844...551,031 JBrowse link
G Cpm carboxypeptidase M ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936545:6,739,658...6,803,501 JBrowse link
G Cpn1 carboxypeptidase N subunit 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936636:145,148...172,865 JBrowse link
G F12 coagulation factor XII ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G Klk1 kallikrein 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936889:534,127...537,913 JBrowse link
G Klkb1 kallikrein B1 ISO RGD PMID:16177542, PMID:18396440 RGD:7401223, RGD:7401224 NCBI chrNW_004936554:3,227,395...3,256,710 JBrowse link
G Kng1 kininogen 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936578:3,255,335...3,281,296 JBrowse link
G LOC101968921 angiotensin-converting enzyme ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936541:4,157,847...4,178,156 JBrowse link
G Mme membrane metalloendopeptidase ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936519:2,513,896...2,595,896 JBrowse link
G Prcp prolylcarboxypeptidase ISO RGD PMID:18396440 RGD:7401224 NCBI chrNW_004936498:11,037,294...11,109,657 JBrowse link
G Serping1 serpin family G member 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936581:4,911,403...4,924,484 JBrowse link
G Xpnpep1 X-prolyl aminopeptidase 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936486:801,563...853,107 JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936479:1,773,797...1,883,606 JBrowse link
kinin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb1 arrestin beta 1 ISO RGD PMID:21145390 RGD:7411621 NCBI chrNW_004936498:4,089,621...4,172,749 JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:21145390 RGD:7411621 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:15734727, PMID:16177542 RGD:7401223, RGD:7401225 NCBI chrNW_004936604:551,774...567,014 JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO RGD PMID:15734727, PMID:16177542 RGD:7401223, RGD:7401225 NCBI chrNW_004936604:548,844...551,031 JBrowse link
G Grk4 G protein-coupled receptor kinase 4 ISO RGD PMID:15734727 RGD:7401225 NCBI chrNW_004936477:20,580,794...20,668,259 JBrowse link
G Kng1 kininogen 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chrNW_004936578:3,255,335...3,281,296 JBrowse link
long term depression term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16904707, PMID:17655746 RGD:1642204, RGD:1642207 NCBI chrNW_004936530:8,286,101...8,612,183 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO RGD PMID:17329210 RGD:1641844 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
long term potentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO RGD PMID:11282364 RGD:1582105 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Egr1 early growth response 1 ISO RGD PMID:16930406 RGD:1626499 NCBI chrNW_004936531:7,625,956...7,629,041 JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 ISO RGD PMID:10580501 RGD:1642498 NCBI chrNW_004936500:12,157,215...12,536,555 JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16904707, PMID:17655746 RGD:1642204, RGD:1642207 NCBI chrNW_004936530:8,286,101...8,612,183 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:16904707, PMID:17655746, PMID:20164351 RGD:1642204, RGD:1642207, RGD:2325882 NCBI chrNW_004936587:3,406,055...3,806,956 JBrowse link
G Kcnd1 potassium voltage-gated channel subfamily D member 1 ISO RGD PMID:16141270 RGD:1581430 NCBI chrNW_004936721:881,162...890,939 JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 ISO RGD PMID:16141270 RGD:1581430 NCBI chrNW_004936605:4,370,222...4,828,972 JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 ISO RGD PMID:16141270 RGD:1581430 NCBI chrNW_004936690:417,907...627,025 JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase ISO RGD PMID:11282364 RGD:1582105 NCBI chrNW_004936523:6,443,571...6,533,122 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO RGD PMID:12764094 RGD:2292620 NCBI chrNW_004936470:10,379,855...10,578,531 JBrowse link
nerve growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO RGD PMID:15728722 RGD:1581104 NCBI chrNW_004936508:12,162,553...12,281,812 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:15546918 RGD:1580675 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
neuron-to-neuron signaling pathway via the chemical synapse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj12 potassium inwardly rectifying channel subfamily J member 12 ISO RGD PMID:15936845 RGD:1581471 NCBI chrNW_004936741:266,311...303,947 JBrowse link
G Kcnj14 potassium inwardly rectifying channel subfamily J member 14 ISO RGD PMID:15936845 RGD:1581471 NCBI chrNW_004936664:2,555,727...2,564,245 JBrowse link
G Kcnj2 potassium inwardly rectifying channel subfamily J member 2 ISO RGD PMID:15936845 RGD:1581471 NCBI chrNW_004936655:3,447,026...3,459,569 JBrowse link
G Kcnj4 potassium inwardly rectifying channel subfamily J member 4 ISO RGD PMID:15936845 RGD:1581471 NCBI chrNW_004936492:2,865,803...2,867,657 JBrowse link
neuron-to-neuron signaling pathway via the electrical synapse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Panx1 pannexin 1 ISO RGD PMID:14597722 RGD:1299639 NCBI chrNW_004936674:736,911...773,406 JBrowse link
G Panx2 pannexin 2 ISO RGD PMID:14597722 RGD:1299639 NCBI chrNW_004936629:618,758...626,446 JBrowse link
Reelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO PID PID:200062 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 ISO PID PID:200062 NCBI chrNW_004936580:5,213,323...5,230,861 JBrowse link
G Cbl Cbl proto-oncogene ISO PID PID:200062 NCBI chrNW_004936542:4,136,389...4,235,746 JBrowse link
G Cdk5 cyclin dependent kinase 5 ISO PID PID:200062 NCBI chrNW_004936527:6,478,934...6,483,848 JBrowse link
G Cdk5r1 cyclin dependent kinase 5 regulatory subunit 1 ISO PID PID:200062 NCBI chrNW_004936538:2,411,194...2,415,106 JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO PID PID:200062 NCBI chrNW_004936619:2,447,686...2,479,589 JBrowse link
G Dab1 DAB adaptor protein 1 ISO PID
RGD
PMID:12670697, PMID:12764038, PMID:16266828 PID:200062, RGD:1358468, RGD:2324967, RGD:727518 NCBI chrNW_004936522:3,498,395...4,612,560 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO PID
RGD
PMID:12778121 PID:200062, RGD:2324970 NCBI chrNW_004936679:388,500...588,518 JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ISO RGD PMID:18237558 RGD:2325284 NCBI chrNW_004936515:8,937,391...9,236,438 JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO PID
RGD
PMID:18237558 PID:200062, RGD:2325284 NCBI chrNW_004936530:8,286,101...8,612,183 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO PID
RGD
PMID:18237558 PID:200062, RGD:2325284 NCBI chrNW_004936587:3,406,055...3,806,956 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO PID PID:200062 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Itga3 integrin subunit alpha 3 ISO PID
RGD
PMID:15583703 PID:200062, RGD:2325851 NCBI chrNW_004936490:11,553,904...11,583,387 JBrowse link
G Itgb1 integrin subunit beta 1 ISO PID
RGD
PMID:15583703 PID:200062, RGD:2325851 NCBI chrNW_004936574:1,465,981...1,495,717 JBrowse link
G Lrp8 LDL receptor related protein 8 ISO PID
RGD
PMID:19846452 PID:200062, RGD:2324974 NCBI chrNW_004936522:7,740,887...7,820,488 JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 ISO PID PID:200062 NCBI chrNW_004936477:20,234,582...20,250,756 JBrowse link
G Map1b microtubule associated protein 1B ISO PID PID:200062 NCBI chrNW_004936549:4,266,371...4,371,579 JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 ISO PID PID:200062 NCBI chrNW_004936588:4,882,191...4,891,807 JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO PID PID:200062 NCBI chrNW_004936599:3,847,637...3,862,895 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO PID PID:200062 NCBI chrNW_004936728:1,775,746...1,893,895 JBrowse link
G Mapt microtubule associated protein tau ISO PID PID:200062 NCBI chrNW_004936541:2,381,411...2,479,984 JBrowse link
G Nck2 NCK adaptor protein 2 ISO PID PID:200062 NCBI chrNW_004936764:141,159...185,482 JBrowse link
G Pafah1b1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 ISO PID
RGD
PMID:17330141 PID:200062, RGD:4107040 NCBI chrNW_004936538:8,612,142...8,693,698 JBrowse link
G Pafah1b2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 ISO RGD PMID:17330141 RGD:4107040 NCBI chrNW_004936542:2,390,904...2,417,596 JBrowse link
G Pafah1b3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 ISO RGD PMID:17330141 RGD:4107040 NCBI chrNW_004936706:212,635...215,498 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200062 NCBI chrNW_004936566:3,924,013...3,951,052 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID
RGD
PMID:17167084 PID:200062, RGD:4108507 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO PID PID:200062 NCBI chrNW_004936690:275,840...363,752 JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 ISO PID PID:200062 NCBI chrNW_004936487:18,305,537...18,411,170 JBrowse link
G Reln reelin ISO PID
RGD
PMID:12670697, PMID:12893944 PID:200062, RGD:1358346, RGD:727518 NCBI chrNW_004936479:19,628,488...20,088,278 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:18237558 RGD:2325284 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Vldlr very low density lipoprotein receptor ISO PID
RGD
PMID:12670697, PMID:12764038, PMID:12893944 PID:200062, RGD:1358346, RGD:1358468, RGD:727518 NCBI chrNW_004936503:2,407,040...2,440,366 JBrowse link
serotonin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 ISO RGD PMID:19095043 RGD:39939084 NCBI chrNW_004936754:1,288,891...1,293,555 JBrowse link
serotonin signaling pathway via receptors engaging G alphas protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chrNW_004936643:47,830...338,891 JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chrNW_004936631:3,721,307...3,785,346 JBrowse link
G Esr1 estrogen receptor 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chrNW_004936489:4,616,839...4,887,179 JBrowse link
G Gnas GNAS complex locus ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chrNW_004936737:1,518,855...1,554,926 JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chrNW_004936591:3,860,668...3,983,305 JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 ISO SMPDB SMP:00309 NCBI chrNW_004936504:6,146,974...6,306,000 JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO SMPDB SMP:00312 NCBI chrNW_004936474:5,848,719...5,858,520 JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO SMPDB SMP:00311 NCBI chrNW_004936601:3,569,626...3,626,782 JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chrNW_004936599:2,345,982...2,348,494 JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chrNW_004936608:1,353,905...1,464,636 JBrowse link
synaptic vesicle exocytosis - neurotransmitter release pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stxbp1 syntaxin binding protein 1 ISO RGD PMID:8247129 RGD:1299066 NCBI chrNW_004936487:15,300,758...15,367,475 JBrowse link
visual phototransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arr3 arrestin 3 ISO RGD PMID:21824527, PMID:22074925 RGD:6893539, RGD:6893556 NCBI chrNW_004936762:1,194,251...1,207,914 JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:12087135 RGD:6893549 NCBI chrNW_004936482:14,091,343...14,107,793 JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 ISO RGD PMID:12087135 RGD:6893549 NCBI chrNW_004936744:1,499,431...1,537,784 JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:12087135 RGD:6893549 NCBI chrNW_004936475:9,844,438...9,908,009 JBrowse link
G Cngb3 cyclic nucleotide gated channel subunit beta 3 ISO RGD PMID:12087135 RGD:6893549 NCBI chrNW_004936544:1,166,896...1,305,339 JBrowse link
G Gnat1 G protein subunit alpha transducin 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936529:1,735,258...1,740,297 JBrowse link
G Gnat2 G protein subunit alpha transducin 2 ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936704:1,079,255...1,093,732 JBrowse link
G Gnb1 G protein subunit beta 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936737:1,518,855...1,554,926 JBrowse link
G Gnb3 G protein subunit beta 3 ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936709:970,169...977,059 JBrowse link
G Gnb5 G protein subunit beta 5 ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936471:13,952,462...14,001,663 JBrowse link
G Gngt1 G protein subunit gamma transducin 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936803:67,933...71,508 JBrowse link
G Gngt2 G protein subunit gamma transducin 2 ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936490:12,292,462...12,294,302 JBrowse link
G Grk1 G protein-coupled receptor kinase 1 ISO RGD PMID:21903131 RGD:6893555 NCBI chrNW_004936472:152,202...165,134 JBrowse link
G Grk7 G protein-coupled receptor kinase 7 ISO RGD PMID:21903131 RGD:6893555 NCBI chrNW_004936540:3,516,706...3,553,102 JBrowse link
G Guca1b guanylate cyclase activator 1B ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936476:17,679,505...17,688,970 JBrowse link
G Gucy2d guanylate cyclase 2D, retinal ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936595:1,235,747...1,250,294 JBrowse link
G Gucy2f guanylate cyclase 2F, retinal ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936499:5,653,384...5,752,732 JBrowse link
G LOC101958197 regulator of G protein signaling 9 ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936541:7,472,195...7,525,220 JBrowse link
G Opn1sw opsin 1, short wave sensitive ISO RGD PMID:21704730 RGD:6893536 NCBI chrNW_004936479:15,696,063...15,702,311 JBrowse link
G Pde6a phosphodiesterase 6A ISO RGD PMID:15224133 RGD:6893540 NCBI chrNW_004936504:5,018,171...5,088,333 JBrowse link
G Pde6b phosphodiesterase 6B ISO RGD PMID:15224133 RGD:6893540 NCBI chrNW_004936477:22,418,037...22,472,251 JBrowse link
G Pde6c phosphodiesterase 6C ISO RGD PMID:15224133 RGD:6893540 NCBI chrNW_004936601:1,343,538...1,393,605 JBrowse link
G Pde6g phosphodiesterase 6G ISO RGD PMID:15224133 RGD:6893540 NCBI chrNW_004936594:5,263,345...5,267,240 JBrowse link
G Pde6h phosphodiesterase 6H ISO RGD PMID:15224133 RGD:6893540 NCBI chrNW_004936587:2,505,755...2,514,103 JBrowse link
G Rcvrn recoverin ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936595:2,873,739...2,882,150 JBrowse link
G Rgs9bp regulator of G protein signaling 9 binding protein ISO RGD PMID:22074925 RGD:6893539 NCBI chrNW_004936570:3,042,233...3,043,884 JBrowse link
G Rho rhodopsin ISO RGD PMID:21704730 RGD:6893536 NCBI chrNW_004936602:896,730...901,480 JBrowse link
G Sag S-antigen visual arrestin ISO RGD PMID:21824527, PMID:22074925 RGD:6893539, RGD:6893556 NCBI chrNW_004936525:3,932,118...3,965,651 JBrowse link
G Slc24a1 solute carrier family 24 member 1 ISO RGD PMID:18690016 RGD:6893550 NCBI chrNW_004936471:25,872,854...25,909,102 JBrowse link
G Slc24a2 solute carrier family 24 member 2 ISO RGD PMID:18690016 RGD:6893550 NCBI chrNW_004936652:1,375,292...1,585,718 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3930
    signaling pathway 1884
      signaling pathway pertinent to the brain and nervous system 226
        Reelin signaling pathway + 32
        altered signaling pathway pertinent to the brain and nervous system + 11
        gasotransmitter mediated signaling pathway + 0
        melatonin signaling pathway 0
        neuron-to-neuron signaling pathways + 128
        neurotrophic factor signaling pathway + 8
        sensory system signaling pathway + 68
        thyroid hormone signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.