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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:signaling pathway pertinent to the brain and nervous system
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Accession:PW:0000059 term browser browse the term
Definition:Those signaling pathways that are involved in or mediate the various aspects of nervous system and/or brain function.


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signaling pathway pertinent to the brain and nervous system term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16600505 RGD:1581409 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase ISO RGD PMID:17786266 RGD:8549506 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
G CHAT choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chr28:1,480,364...1,528,858
Ensembl chr28:1,482,202...1,528,776
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:23759942 RGD:8549590 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:19478075 RGD:8549592 NCBI chr28:29,424,350...29,636,552
Ensembl chr28:29,424,593...29,632,741
JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:22685433 RGD:8549594 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:22685433 RGD:8549594 NCBI chr38:19,771,454...19,778,917
Ensembl chr38:19,771,441...19,779,190
JBrowse link
G RGS6 regulator of G protein signaling 6 ISO RGD PMID:22685433 RGD:8549594 NCBI chr 8:45,392,246...45,975,073
Ensembl chr 8:45,438,239...46,009,049
JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chr28:1,476,873...1,478,538
Ensembl chr28:1,476,774...1,478,505
JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chr10:35,879,880...35,908,203
Ensembl chr10:35,883,245...35,908,569
JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM2 cholinergic receptor muscarinic 2 ISO RGD PMID:23841840 RGD:8549585 NCBI chr16:11,515,727...11,665,651
Ensembl chr16:11,515,426...11,664,977
JBrowse link
G CHRM4 cholinergic receptor muscarinic 4 ISO RGD PMID:23841840 RGD:8549585 NCBI chr18:43,077,115...43,084,298
Ensembl chr18:43,082,404...43,083,840
JBrowse link
G GNAI1 G protein subunit alpha i1 ISO RGD PMID:23759942 RGD:8549590 NCBI chr18:19,924,381...19,952,956
Ensembl chr18:19,924,235...19,951,244
JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:23759942 RGD:8549590 NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697
JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM1 cholinergic receptor muscarinic 1 ISO RGD PMID:23841840 RGD:8549585 NCBI chr18:53,783,938...53,797,750
Ensembl chr18:53,795,326...53,796,708
JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:23841840 RGD:8549585 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613
JBrowse link
G CHRM5 cholinergic receptor muscarinic 5 ISO RGD PMID:23841840 RGD:8549585 NCBI chr30:988,764...1,074,599
Ensembl chr30:990,208...991,806
JBrowse link
G GNA14 G protein subunit alpha 14 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 1:80,992,992...81,178,362
Ensembl chr 1:80,992,863...81,177,674
JBrowse link
G GNAQ G protein subunit alpha q ISO RGD PMID:23759942 RGD:8549590 NCBI chr 1:80,733,530...80,928,065
Ensembl chr 1:80,715,366...80,928,065
JBrowse link
acetylcholine signaling pathway via nicotinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase ISO RGD PMID:17786266 RGD:8549506 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
G AGRN agrin ISO RGD PMID:23032192 RGD:8549508 NCBI chr 5:56,239,621...56,273,679
Ensembl chr 5:56,239,701...56,272,745
JBrowse link
G CHAT choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chr28:1,480,364...1,528,858
Ensembl chr28:1,482,202...1,528,776
JBrowse link
G CHRNA1 cholinergic receptor nicotinic alpha 1 subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr36:18,726,243...18,742,505
Ensembl chr36:18,726,243...18,742,505
JBrowse link
G CHRNA10 cholinergic receptor nicotinic alpha 10 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr21:26,216,862...26,233,226 JBrowse link
G CHRNA2 cholinergic receptor nicotinic alpha 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr25:30,117,384...30,137,223
Ensembl chr25:30,117,239...30,135,599
JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr13:38,330,287...38,343,142
Ensembl chr13:38,328,814...38,346,246
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr24:47,024,948...47,036,507
Ensembl chr24:47,025,187...47,042,266
JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr13:38,343,966...38,355,534
Ensembl chr13:38,346,104...38,355,468
JBrowse link
G CHRNA6 cholinergic receptor nicotinic alpha 6 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr16:22,990,377...23,009,257
Ensembl chr16:22,990,167...23,009,106
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 3:36,852,082...37,164,930
Ensembl chr 3:36,852,543...36,978,399
JBrowse link
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 3:72,190,431...72,204,092
Ensembl chr 3:72,190,555...72,203,404
JBrowse link
G CHRNB1 cholinergic receptor nicotinic beta 1 subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr 5:32,375,152...32,383,517
Ensembl chr 5:32,375,215...32,382,929
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 7:42,786,505...42,797,976
Ensembl chr 7:42,789,600...42,795,722
JBrowse link
G CHRNB3 cholinergic receptor nicotinic beta 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr16:23,021,652...23,040,907
Ensembl chr16:23,021,645...23,048,347
JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr13:38,312,537...38,327,242
Ensembl chr13:38,312,173...38,328,341
JBrowse link
G CHRND cholinergic receptor nicotinic delta subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr25:44,166,089...44,175,047
Ensembl chr25:44,165,819...44,174,216
JBrowse link
G CHRNE cholinergic receptor nicotinic epsilon subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr 5:31,696,710...31,707,639
Ensembl chr 5:31,696,993...31,708,671
JBrowse link
G CHRNG cholinergic receptor nicotinic gamma subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr25:44,178,149...44,183,623
Ensembl chr25:44,178,181...44,183,626
JBrowse link
G DOK7 docking protein 7 ISO RGD PMID:23032192 RGD:8549508 NCBI chr 3:60,873,298...60,897,047
Ensembl chr 3:60,869,206...60,897,318
JBrowse link
G LRP4 LDL receptor related protein 4 ISO RGD PMID:23032192 RGD:8549508 NCBI chr18:42,616,683...42,667,297
Ensembl chr18:42,616,426...42,665,794
JBrowse link
G MUSK muscle associated receptor tyrosine kinase ISO RGD PMID:23032192 RGD:8549508 NCBI chr11:65,552,320...65,642,165
Ensembl chr11:65,551,889...65,642,349
JBrowse link
G RAPSN receptor associated protein of the synapse ISO RGD PMID:23032192 RGD:8549508 NCBI chr18:42,199,160...42,210,668
Ensembl chr18:42,199,412...42,210,673
JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chr28:1,476,873...1,478,538
Ensembl chr28:1,476,774...1,478,505
JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chr10:35,879,880...35,908,203
Ensembl chr10:35,883,245...35,908,569
JBrowse link
altered clathrin-dependent synaptic vesicle endocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 ISO RGD PMID:25302295 RGD:10450553 NCBI chr 5:44,882,111...45,021,152
Ensembl chr 5:44,884,283...45,120,203
JBrowse link
G SYNJ1 synaptojanin 1 ISO RGD PMID:25302295 RGD:10450553 NCBI chr31:27,308,169...27,399,226
Ensembl chr31:27,308,169...27,399,197
JBrowse link
altered Reelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB1 DAB adaptor protein 1 ISO RGD PMID:12670697, PMID:12764038, PMID:16266828 RGD:1358468, RGD:2324967, RGD:727518 NCBI chr 5:51,397,837...52,505,513
Ensembl chr 5:52,231,141...52,502,336
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:12778121 RGD:2324970 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541
JBrowse link
G ITGA3 integrin subunit alpha 3 ISO RGD PMID:15583703 RGD:2325851 NCBI chr 9:26,065,792...26,095,649
Ensembl chr 9:26,062,393...26,094,422
JBrowse link
G ITGB1 integrin subunit beta 1 ISO RGD PMID:15583703 RGD:2325851 NCBI chr 2:3,728,472...3,757,696
Ensembl chr 2:3,670,596...3,756,961
JBrowse link
G LRP8 LDL receptor related protein 8 ISO RGD PMID:19846452 RGD:2324974 NCBI chr 5:55,604,878...55,684,666
Ensembl chr 5:55,604,878...55,699,736
JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 ISO RGD PMID:17330141 RGD:4107040 NCBI chr 9:46,648,057...46,731,259
Ensembl chr 9:46,648,052...46,771,400
JBrowse link
G PAFAH1B3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 ISO RGD PMID:17330141 RGD:4107040 NCBI chr 1:112,078,131...112,080,874
Ensembl chr 1:112,063,074...112,080,873
JBrowse link
G RELN reelin ISO RGD PMID:12670697, PMID:12764038 RGD:1358468, RGD:727518 NCBI chr18:16,275,822...16,773,875
Ensembl chr18:16,275,837...16,773,875
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:18237558 RGD:2325284 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
G VLDLR very low density lipoprotein receptor ISO RGD PMID:12764038 RGD:1358468 NCBI chr 1:91,242,010...91,277,030
Ensembl chr 1:91,241,509...91,272,495
JBrowse link
altered visual phototransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:20212494 RGD:8547536 NCBI chr13:43,831,159...43,864,276
Ensembl chr13:43,831,163...43,864,276
JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:20212494 RGD:8547536 NCBI chr 2:58,574,552...58,641,631
Ensembl chr 2:58,574,552...58,640,812
JBrowse link
G GUCA1B guanylate cyclase activator 1B ISO RGD PMID:20212494 RGD:8547536 NCBI chr12:10,796,961...10,806,796
Ensembl chr12:10,797,921...10,834,237
JBrowse link
G PDE6A phosphodiesterase 6A ISO RGD PMID:20212494 RGD:8547536 NCBI chr 4:59,103,965...59,163,857
Ensembl chr 4:59,103,945...59,163,857
JBrowse link
G PDE6B phosphodiesterase 6B ISO RGD PMID:20212494 RGD:8547536 NCBI chr 3:91,746,571...91,775,372
Ensembl chr 3:91,746,571...91,775,372
JBrowse link
G PDE6G phosphodiesterase 6G ISO RGD PMID:20212494 RGD:8547536 NCBI chr 9:525,123...529,406
Ensembl chr 9:526,577...529,526
JBrowse link
G RHO rhodopsin ISO RGD PMID:20212494 RGD:8547536 NCBI chr20:5,630,735...5,638,906 JBrowse link
G SAG S-antigen visual arrestin ISO RGD PMID:20212494 RGD:8547536 NCBI chr25:44,800,141...44,843,580
Ensembl chr25:44,812,362...44,843,579
JBrowse link
auditory mechanotransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTB actin beta ISO RGD PMID:20624897 RGD:8547669 NCBI chr 6:12,421,006...12,424,449
Ensembl chr 6:12,418,932...12,462,845
JBrowse link
G ACTG1 actin gamma 1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr 9:635,978...638,328
Ensembl chr 9:635,978...638,328
JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr 3:17,866,459...18,351,532
Ensembl chr 3:17,866,808...18,351,532
JBrowse link
G CDH23 cadherin related 23 ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr 4:22,206,972...22,570,875
Ensembl chr 4:22,207,001...22,571,131
JBrowse link
G ESPN espin ISO RGD PMID:19804752, PMID:20624897 RGD:8547667, RGD:8547669 NCBI chr 5:60,285,185...60,316,261
Ensembl chr 5:60,285,312...60,315,676
JBrowse link
G MYO15A myosin XVA ISO RGD PMID:19804752 RGD:8547667 NCBI chr 5:41,369,484...41,421,303
Ensembl chr 5:41,370,509...41,392,881
JBrowse link
G MYO1C myosin IC ISO RGD PMID:19804752 RGD:8547667 NCBI chr 9:45,635,295...45,658,226
Ensembl chr 9:45,636,208...45,658,035
JBrowse link
G MYO3A myosin IIIA ISO RGD PMID:19804752 RGD:8547667 NCBI chr 2:7,455,125...7,695,483
Ensembl chr 2:7,455,625...7,696,043
JBrowse link
G MYO6 myosin VI ISO RGD PMID:20624897, PMID:22715884 RGD:8547669, RGD:8547672 NCBI chr12:37,359,200...37,502,342
Ensembl chr12:37,413,570...37,500,724
JBrowse link
G MYO7A myosin VIIA ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr21:21,539,735...21,624,063
Ensembl chr21:21,539,785...21,624,279
JBrowse link
G OTOF otoferlin ISO RGD PMID:22715884 RGD:8547672 NCBI chr17:20,518,480...20,619,713
Ensembl chr17:20,518,813...20,614,750
JBrowse link
G PCDH15 protocadherin related 15 ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr26:33,426,728...34,589,208
Ensembl chr26:33,719,839...34,588,017
JBrowse link
G PLS1 plastin 1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr23:38,243,631...38,347,195
Ensembl chr23:38,243,024...38,347,202
JBrowse link
G PLS3 plastin 3 ISO RGD PMID:20624897 RGD:8547669 NCBI chr  X:88,308,817...88,399,682
Ensembl chr  X:88,308,888...88,398,810
JBrowse link
G PTPRQ protein tyrosine phosphatase receptor type Q ISO RGD PMID:20624897 RGD:8547669 NCBI chr15:22,771,653...23,017,694
Ensembl chr15:22,825,348...23,013,762
JBrowse link
G SLC17A8 solute carrier family 17 member 8 ISO RGD PMID:22715884 RGD:8547672 NCBI chr15:39,443,790...39,489,988
Ensembl chr15:39,443,518...39,486,595
JBrowse link
G USH1C USH1 protein network component harmonin ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr21:40,055,786...40,100,685
Ensembl chr21:40,055,730...40,101,430
JBrowse link
G USH1G USH1 protein network component sans ISO RGD PMID:22177415 RGD:8547671 NCBI chr 9:5,527,935...5,532,940
Ensembl chr 9:5,528,492...5,533,900
JBrowse link
G USH2A usherin ISO RGD PMID:20624897 RGD:8547669 NCBI chr38:11,063,221...11,750,444
Ensembl chr38:11,063,817...11,750,444
JBrowse link
G WHRN whirlin ISO RGD PMID:19804752 RGD:8547667 NCBI chr11:68,617,383...68,699,824
Ensembl chr11:68,617,377...68,699,977
JBrowse link
brain-derived neurotrophic factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor ISO RGD PMID:23670594 RGD:11062158 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480
JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr10:11,445,843...11,552,325
Ensembl chr10:11,539,994...11,552,890
JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr 1:74,447,927...74,777,910
Ensembl chr 1:74,449,060...74,777,032
JBrowse link
G SHC1 SHC adaptor protein 1 ISO RGD PMID:23670594 RGD:11062158 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276
JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:23670594 RGD:11062158 NCBI chr31:26,058,858...26,440,059
Ensembl chr31:25,932,697...26,202,756
JBrowse link
clathrin-dependent synaptic vesicle endocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP2A1 adaptor related protein complex 2 subunit alpha 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 1:106,752,326...106,784,803
Ensembl chr 1:106,751,800...106,784,663
JBrowse link
G AP2A2 adaptor related protein complex 2 subunit alpha 2 ISO RGD PMID:22763746 RGD:10450547 NCBI chr18:45,269,962...45,358,020
Ensembl chr18:45,253,772...45,358,018
JBrowse link
G AP2B1 adaptor related protein complex 2 subunit beta 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 9:37,946,761...38,078,074
Ensembl chr 9:37,946,788...38,078,041
JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr34:17,071,199...17,080,445
Ensembl chr34:17,071,235...17,080,445
JBrowse link
G AP2S1 adaptor related protein complex 2 subunit sigma 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 1:109,094,098...109,105,233
Ensembl chr 1:109,082,221...109,105,230
JBrowse link
G CLTA clathrin light chain A ISO RGD PMID:22763746 RGD:10450547 NCBI chr11:52,636,328...52,681,258
Ensembl chr11:52,615,039...52,681,270
JBrowse link
G CLTB clathrin light chain B ISO RGD PMID:22763746 RGD:10450547 NCBI chr 4:36,915,106...36,935,565
Ensembl chr 4:36,791,891...36,935,278
JBrowse link
G CLTC clathrin heavy chain ISO RGD PMID:22763746 RGD:10450547 NCBI chr 9:34,116,344...34,183,023
Ensembl chr 9:34,116,634...34,182,719
JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 5:44,882,111...45,021,152
Ensembl chr 5:44,884,283...45,120,203
JBrowse link
G DNM1 dynamin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 9:55,252,802...55,298,244
Ensembl chr 9:55,252,347...55,298,244
JBrowse link
G DNM3 dynamin 3 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 7:26,569,708...27,024,939
Ensembl chr 7:26,574,453...27,024,759
JBrowse link
G DNMBP dynamin binding protein ISO RGD PMID:22763746 RGD:10450547 NCBI chr28:12,751,870...12,825,654
Ensembl chr28:12,753,305...12,825,494
JBrowse link
G EPN1 epsin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 1:102,059,022...102,073,665
Ensembl chr 1:102,059,181...102,073,561
JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 ISO RGD PMID:22763746 RGD:10450547 NCBI chr15:9,834,285...9,895,755
Ensembl chr15:9,787,260...9,893,540
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 5:11,292,219...11,296,851
Ensembl chr 5:11,292,262...11,296,797
JBrowse link
G ITSN1 intersectin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr31:29,144,754...29,360,134 JBrowse link
G PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma ISO RGD PMID:22763746 RGD:10450547 NCBI chr20:55,751,055...55,801,740
Ensembl chr20:55,751,158...55,799,160
JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 ISO RGD PMID:22763746 RGD:10450547 NCBI chr20:55,279,622...55,311,579
Ensembl chr20:55,279,621...55,311,536
JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr11:37,720,793...37,769,027
Ensembl chr11:37,577,053...37,767,572
JBrowse link
G SH3GL3 SH3 domain containing GRB2 like 3, endophilin A3 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 3:55,287,460...55,340,736
Ensembl chr 3:55,287,460...55,340,571
JBrowse link
G SNAP91 synaptosome associated protein 91 ISO RGD PMID:22763746 RGD:10450547 NCBI chr12:43,919,925...44,058,315
Ensembl chr12:43,919,925...44,058,616
JBrowse link
G SYNJ1 synaptojanin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr31:27,308,169...27,399,226
Ensembl chr31:27,308,169...27,399,197
JBrowse link
dopamine signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK5 cyclin dependent kinase 5 ISO RGD PMID:21927600 RGD:11041163 NCBI chr16:15,105,177...15,113,085
Ensembl chr16:15,101,230...15,109,269
JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 ISO RGD PMID:21927600 RGD:11041163 NCBI chr 4:59,435,530...59,485,591
Ensembl chr 4:59,435,764...59,483,475
JBrowse link
G DRD1 dopamine receptor D1 ISO heterodimer coupled to Galphaq RGD PMID:17314300, PMID:25671228 RGD:11041142, RGD:1625010 NCBI chr 4:37,550,454...37,554,641
Ensembl chr 4:37,549,708...37,553,287
JBrowse link
G DRD2 dopamine receptor D2 ISO heterodimer coupled to Galphaq RGD PMID:12121979, PMID:16490190, PMID:17314300, PMID:25671228 RGD:11041142, RGD:1581445, RGD:1625010, RGD:1625068 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:16490190 RGD:1625068 NCBI chr33:18,369,362...18,414,465
Ensembl chr33:18,372,865...18,412,277
JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:25671228 RGD:11041142 NCBI chr 3:69,621,187...69,623,522
Ensembl chr 3:69,621,734...69,623,893
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr18:50,062,352...50,065,166
Ensembl chr18:50,062,352...50,065,166
JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr17:22,680,691...22,699,999
Ensembl chr17:22,679,783...22,699,999
JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chr26:8,497,350...8,518,467
Ensembl chr26:8,495,067...8,518,675
JBrowse link
G PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B ISO RGD PMID:21303898, PMID:21927600 RGD:11041134, RGD:11041163 NCBI chr 9:22,838,198...22,847,924
Ensembl chr 9:22,838,576...22,848,142
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052
JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr16:33,532,703...33,567,011
Ensembl chr16:33,532,958...33,566,640
JBrowse link
G PPP2R3A protein phosphatase 2 regulatory subunit B''alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr23:32,441,130...32,628,588
Ensembl chr23:32,471,921...32,626,548
JBrowse link
G PPP2R5D protein phosphatase 2 regulatory subunit B'delta ISO RGD PMID:21927600 RGD:11041163 NCBI chr12:11,519,194...11,540,658
Ensembl chr12:11,519,092...11,540,109
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr32:22,688,141...22,996,693
Ensembl chr32:22,688,143...22,996,688
JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr 4:23,976,023...24,028,139
Ensembl chr 4:23,977,317...24,028,153
JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chr25:34,732,268...34,839,743
Ensembl chr25:34,725,226...34,838,994
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669
JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr 6:63,615,445...63,729,386
Ensembl chr 6:63,618,323...63,730,146
JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr21:41,097,563...41,154,247
Ensembl chr21:41,097,569...41,136,706
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16529858 RGD:1581410 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
dopamine signaling pathway via D1 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00308 NCBI chr34:6,139,931...6,527,677
Ensembl chr34:6,140,276...6,527,677
JBrowse link
G ADCY5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chr33:26,345,617...26,490,120
Ensembl chr33:26,345,617...26,504,616
JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:21303898 RGD:11041134 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB
RGD
PMID:21303898 RGD:11041134, SMP:00308 NCBI chr 4:37,550,454...37,554,641
Ensembl chr 4:37,549,708...37,553,287
JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 3:69,621,187...69,623,522
Ensembl chr 3:69,621,734...69,623,893
JBrowse link
G GNAL G protein subunit alpha L ISO RGD PMID:24144882 RGD:11041135 NCBI chr 7:77,378,134...77,521,215
Ensembl chr 7:77,413,986...77,521,042
JBrowse link
G GNAS GNAS complex locus ISO SMPDB SMP:00308 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657
JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00308 NCBI chr 5:56,777,854...56,879,619
Ensembl chr 5:56,779,354...56,817,295
JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00308 NCBI chr 6:77,316,649...77,378,356
Ensembl chr 6:77,338,685...77,374,937
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr26:19,385,059...19,512,528
Ensembl chr26:19,385,058...19,516,077
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr28:29,424,350...29,636,552
Ensembl chr28:29,424,593...29,632,741
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 4:35,927,470...35,943,218
Ensembl chr 4:35,913,472...35,943,221
JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00308 NCBI chr 6:63,615,445...63,729,386
Ensembl chr 6:63,618,323...63,730,146
JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr38:19,771,454...19,778,917
Ensembl chr38:19,771,441...19,779,190
JBrowse link
G RGS7 regulator of G protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 7:32,296,337...32,792,085
Ensembl chr 7:32,296,695...32,792,036
JBrowse link
G RGS7BP regulator of G protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chr 2:50,430,806...50,530,092
Ensembl chr 2:50,430,844...50,528,673
JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 9:14,809,977...14,905,299
Ensembl chr 9:14,809,864...14,905,197
JBrowse link
dopamine signaling pathway via D2 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chr33:26,345,617...26,490,120
Ensembl chr33:26,345,617...26,504,616
JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:21303898 RGD:11041134 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr33:18,369,362...18,414,465
Ensembl chr33:18,372,865...18,412,277
JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:24831693 RGD:11041136 NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697
JBrowse link
G GNAO1 G protein subunit alpha o1 ISO RGD PMID:24831693 RGD:11041136 NCBI chr 2:59,805,675...59,980,782
Ensembl chr 2:59,806,689...59,980,398
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898, PMID:23940634 RGD:11041134, RGD:13792715 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr26:19,385,059...19,512,528
Ensembl chr26:19,385,058...19,516,077
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr28:29,424,350...29,636,552
Ensembl chr28:29,424,593...29,632,741
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 4:35,927,470...35,943,218
Ensembl chr 4:35,913,472...35,943,221
JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr38:19,771,454...19,778,917
Ensembl chr38:19,771,441...19,779,190
JBrowse link
G RGS7 regulator of G protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 7:32,296,337...32,792,085
Ensembl chr 7:32,296,695...32,792,036
JBrowse link
G RGS7BP regulator of G protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chr 2:50,430,806...50,530,092
Ensembl chr 2:50,430,844...50,528,673
JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 9:14,809,977...14,905,299
Ensembl chr 9:14,809,864...14,905,197
JBrowse link
epinephrine signaling pathway via adrenergic receptor beta term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19110970 RGD:4140391 NCBI chr28:24,908,224...24,909,684
Ensembl chr28:24,908,224...24,909,684
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:19110970 RGD:4140391 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:18268361, PMID:19229505 RGD:4140419, RGD:5135529 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:18268361, PMID:19229505 RGD:4140419, RGD:5135529 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G GNAS GNAS complex locus ISO RGD PMID:19110970 RGD:4140391 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:19110970, PMID:19229505 RGD:4140391, RGD:5135529 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:19110970, PMID:19229505 RGD:4140391, RGD:5135529 NCBI chr28:29,424,350...29,636,552
Ensembl chr28:29,424,593...29,632,741
JBrowse link
G SNX13 sorting nexin 13 ISO RGD PMID:17173929 RGD:4140388 NCBI chr14:32,173,630...32,291,039
Ensembl chr14:32,173,181...32,291,039
JBrowse link
excitatory synaptic transmission pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISO RGD PMID:17314300 RGD:1625010 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:16477151 RGD:1642190 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16477151 RGD:1642190 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:16477151 RGD:1642190 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680
JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO RGD PMID:16477151 RGD:1642190 NCBI chr11:58,271,808...58,421,887
Ensembl chr11:58,273,377...58,421,761
JBrowse link
G GRIN3B glutamate ionotropic receptor NMDA type subunit 3B ISO RGD PMID:11823786 RGD:632842 NCBI chr20:57,703,569...57,710,119 JBrowse link
G KCND1 potassium voltage-gated channel subfamily D member 1 ISO RGD PMID:16141270 RGD:1581430 NCBI chr  X:42,111,817...42,119,939
Ensembl chr  X:42,111,837...42,118,375
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO RGD PMID:16141270 RGD:1581430 NCBI chr17:63,470,829...63,668,354
Ensembl chr17:63,470,415...63,668,035
JBrowse link
G LOC607881 potassium voltage-gated channel subfamily D member 2-like ISO RGD PMID:16141270 RGD:1581430
Inhibitory synaptic transmission pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRA1 glycine receptor alpha 1 ISO RGD PMID:14749434 RGD:1598573 NCBI chr 4:57,443,094...57,541,494
Ensembl chr 4:57,443,999...57,528,376
JBrowse link
G GLRB glycine receptor beta ISO RGD PMID:14749434 RGD:1598573 NCBI chr15:54,429,131...54,519,844
Ensembl chr15:54,429,765...54,518,456
JBrowse link
G GPHN gephyrin ISO RGD PMID:14976213 RGD:1300220 NCBI chr 8:40,585,625...41,204,007
Ensembl chr 8:40,585,883...41,203,245
JBrowse link
kallikrein-kinin cascade pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:16177542 RGD:7401223 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr 8:65,017,655...65,028,899 JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:16177542 RGD:7401223 NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407
JBrowse link
G CPM carboxypeptidase M ISO RGD PMID:16177542 RGD:7401223 NCBI chr10:10,968,830...10,999,887 JBrowse link
G CPN1 carboxypeptidase N subunit 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr28:12,875,737...12,902,514
Ensembl chr28:12,875,249...12,902,264
JBrowse link
G F12 coagulation factor XII ISO RGD PMID:16177542 RGD:7401223 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025
JBrowse link
G KLK1 kallikrein 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr 1:106,009,125...106,028,331
Ensembl chr 1:105,963,564...106,028,331
JBrowse link
G KLKB1 kallikrein B1 ISO RGD PMID:16177542, PMID:18396440 RGD:7401223, RGD:7401224 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292
JBrowse link
G KNG1 kininogen 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081
JBrowse link
G LOC477699 alpha-2-macroglobulin ISO RGD PMID:16177542 RGD:7401223 NCBI chr27:36,654,328...36,695,775 JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:16177542 RGD:7401223 NCBI chr23:48,966,222...49,059,919
Ensembl chr23:48,971,066...49,059,919
JBrowse link
G PRCP prolylcarboxypeptidase ISO RGD PMID:18396440 RGD:7401224 NCBI chr21:16,219,688...16,285,186
Ensembl chr21:16,219,831...16,285,188
JBrowse link
G SERPINA4 serpin family A member 4 ISO RGD PMID:16177542 RGD:7401223 NCBI chr 8:63,552,033...63,560,667
Ensembl chr 8:63,552,107...63,560,667
JBrowse link
G SERPING1 serpin family G member 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr18:38,570,354...38,580,751
Ensembl chr18:38,570,607...38,581,665
JBrowse link
G XPNPEP1 X-prolyl aminopeptidase 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr28:21,267,588...21,322,044
Ensembl chr28:21,246,467...21,321,953
JBrowse link
G XPNPEP2 X-prolyl aminopeptidase 2 ISO RGD PMID:16177542 RGD:7401223 NCBI chr  X:100,951,679...100,979,666
Ensembl chr  X:100,951,888...100,978,766
JBrowse link
kinin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 ISO RGD PMID:21145390 RGD:7411621 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:21145390 RGD:7411621 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:15734727, PMID:16177542 RGD:7401223, RGD:7401225 NCBI chr 8:65,017,655...65,028,899 JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:15734727, PMID:16177542 RGD:7401223, RGD:7401225 NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO RGD PMID:15734727 RGD:7401225 NCBI chr 3:61,233,066...61,331,094
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
G KNG1 kininogen 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081
JBrowse link
long term depression term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16904707, PMID:17655746 RGD:1642204, RGD:1642207 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:17329210 RGD:1641844 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666
JBrowse link
long term potentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11282364 RGD:1582105 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G EGR1 early growth response 1 ISO RGD PMID:16930406 RGD:1626499 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575
JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 ISO RGD PMID:10580501 RGD:1642498 NCBI chr31:24,477,319...24,839,502
Ensembl chr31:24,478,696...24,839,434
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16904707, PMID:17655746 RGD:1642204, RGD:1642207 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:16904707, PMID:17655746, PMID:20164351 RGD:1642204, RGD:1642207, RGD:2325882 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680
JBrowse link
G KCND1 potassium voltage-gated channel subfamily D member 1 ISO RGD PMID:16141270 RGD:1581430 NCBI chr  X:42,111,817...42,119,939
Ensembl chr  X:42,111,837...42,118,375
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO RGD PMID:16141270 RGD:1581430 NCBI chr17:63,470,829...63,668,354
Ensembl chr17:63,470,415...63,668,035
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO RGD PMID:11282364 RGD:1582105 NCBI chr 3:12,668,994...12,766,712
Ensembl chr 3:12,681,577...12,767,183
JBrowse link
G LOC607881 potassium voltage-gated channel subfamily D member 2-like ISO RGD PMID:16141270 RGD:1581430
G PTK2 protein tyrosine kinase 2 ISO RGD PMID:12764094 RGD:2292620 NCBI chr13:35,302,439...35,541,336
Ensembl chr13:35,303,380...35,541,294
JBrowse link
nerve growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO RGD PMID:15728722 RGD:1581104 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:15546918 RGD:1580675 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
neuron-to-neuron signaling pathway via the chemical synapse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNJ12 potassium inwardly rectifying channel subfamily J member 12 ISO RGD PMID:15936845 RGD:1581471 NCBI chr 5:42,819,412...42,860,916
Ensembl chr 5:42,850,372...42,860,899
JBrowse link
G KCNJ14 potassium inwardly rectifying channel subfamily J member 14 ISO RGD PMID:15936845 RGD:1581471 NCBI chr 1:107,804,400...107,813,888
Ensembl chr 1:107,806,285...107,809,199
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO RGD PMID:15936845 RGD:1581471 NCBI chr 9:16,468,938...16,475,722
Ensembl chr 9:16,468,938...16,475,722
JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO RGD PMID:15936845 RGD:1581471 NCBI chr10:26,321,274...26,348,978
Ensembl chr10:26,347,140...26,348,486
JBrowse link
neuron-to-neuron signaling pathway via the electrical synapse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PANX1 pannexin 1 ISO RGD PMID:14597722 RGD:1299639 NCBI chr21:6,665,730...6,715,272
Ensembl chr21:6,668,269...6,715,858
JBrowse link
G PANX2 pannexin 2 ISO RGD PMID:14597722 RGD:1299639 NCBI chr10:17,052,972...17,059,756
Ensembl chr10:17,052,956...17,055,880
JBrowse link
Reelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200062 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 ISO PID PID:200062 NCBI chr 7:41,835,322...41,850,488
Ensembl chr 7:41,812,353...41,850,488
JBrowse link
G CBL Cbl proto-oncogene ISO PID PID:200062 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G CDK5 cyclin dependent kinase 5 ISO PID PID:200062 NCBI chr16:15,105,177...15,113,085
Ensembl chr16:15,101,230...15,109,269
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 ISO PID PID:200062 NCBI chr 9:40,481,111...40,502,689
Ensembl chr 9:40,501,646...40,502,569
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO PID PID:200062 NCBI chr26:30,542,276...30,582,479
Ensembl chr26:30,545,311...30,581,964
JBrowse link
G DAB1 DAB adaptor protein 1 ISO PID
RGD
PMID:12670697, PMID:12764038, PMID:16266828 PID:200062, RGD:1358468, RGD:2324967, RGD:727518 NCBI chr 5:51,397,837...52,505,513
Ensembl chr 5:52,231,141...52,502,336
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO PID
RGD
PMID:12778121 PID:200062, RGD:2324970 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO RGD PMID:18237558 RGD:2325284 NCBI chr 4:55,801,269...56,103,383
Ensembl chr 4:55,803,296...56,103,669
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO PID
RGD
PMID:18237558 PID:200062, RGD:2325284 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO PID
RGD
PMID:18237558 PID:200062, RGD:2325284 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO PID PID:200062 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666
JBrowse link
G ITGA3 integrin subunit alpha 3 ISO PID
RGD
PMID:15583703 PID:200062, RGD:2325851 NCBI chr 9:26,065,792...26,095,649
Ensembl chr 9:26,062,393...26,094,422
JBrowse link
G ITGB1 integrin subunit beta 1 ISO PID
RGD
PMID:15583703 PID:200062, RGD:2325851 NCBI chr 2:3,728,472...3,757,696
Ensembl chr 2:3,670,596...3,756,961
JBrowse link
G LRP8 LDL receptor related protein 8 ISO PID
RGD
PMID:19846452 PID:200062, RGD:2324974 NCBI chr 5:55,604,878...55,684,666
Ensembl chr 5:55,604,878...55,699,736
JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 ISO PID PID:200062 NCBI chr 3:60,840,804...60,852,821
Ensembl chr 3:60,840,882...60,901,258
JBrowse link
G MAP1B microtubule associated protein 1B ISO PID PID:200062 NCBI chr 2:55,175,000...55,258,160
Ensembl chr 2:55,174,837...55,253,975
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO PID PID:200062 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150
JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 ISO PID PID:200062 NCBI chr18:51,593,641...51,609,245
Ensembl chr18:51,594,274...51,608,696
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO PID PID:200062 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401
JBrowse link
G MAPT microtubule associated protein tau ISO PID PID:200062 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349
JBrowse link
G NCK2 NCK adaptor protein 2 ISO PID PID:200062 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994
JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 ISO PID
RGD
PMID:17330141 PID:200062, RGD:4107040 NCBI chr 9:46,648,057...46,731,259
Ensembl chr 9:46,648,052...46,771,400
JBrowse link
G PAFAH1B3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 ISO RGD PMID:17330141 RGD:4107040 NCBI chr 1:112,078,131...112,080,874
Ensembl chr 1:112,063,074...112,080,873
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200062 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID
RGD
PMID:17167084 PID:200062, RGD:4108507 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO PID PID:200062 NCBI chr17:63,725,812...63,795,359
Ensembl chr17:63,726,248...63,746,881
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO PID PID:200062 NCBI chr 9:52,429,204...52,566,775
Ensembl chr 9:52,450,597...52,563,778
JBrowse link
G RELN reelin ISO PID
RGD
PMID:12670697, PMID:12893944 PID:200062, RGD:1358346, RGD:727518 NCBI chr18:16,275,822...16,773,875
Ensembl chr18:16,275,837...16,773,875
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:18237558 RGD:2325284 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
G VLDLR very low density lipoprotein receptor ISO PID
RGD
PMID:12670697, PMID:12764038, PMID:12893944 PID:200062, RGD:1358346, RGD:1358468, RGD:727518 NCBI chr 1:91,242,010...91,277,030
Ensembl chr 1:91,241,509...91,272,495
JBrowse link
serotonin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 ISO RGD PMID:19095043 RGD:39939084 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051
JBrowse link
serotonin signaling pathway via receptors engaging G alphas protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr34:6,139,931...6,527,677
Ensembl chr34:6,140,276...6,527,677
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556
JBrowse link
G ESR1 estrogen receptor 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544
JBrowse link
G GNAS GNAS complex locus ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657
JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 5:56,777,854...56,879,619
Ensembl chr 5:56,779,354...56,817,295
JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 6:77,316,649...77,378,356
Ensembl chr 6:77,338,685...77,374,937
JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 ISO SMPDB SMP:00309 NCBI chr 4:60,224,534...60,359,244
Ensembl chr 4:60,185,056...60,353,439
JBrowse link
G HTR6 5-hydroxytryptamine receptor 6 ISO SMPDB SMP:00312 NCBI chr 2:79,022,790...79,033,975
Ensembl chr 2:79,022,775...79,033,975
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO SMPDB SMP:00311 NCBI chr28:5,438,872...5,524,385
Ensembl chr28:5,440,388...5,524,191
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr18:50,062,352...50,065,166
Ensembl chr18:50,062,352...50,065,166
JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 6:63,615,445...63,729,386
Ensembl chr 6:63,618,323...63,730,146
JBrowse link
synaptic vesicle exocytosis - neurotransmitter release pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:8247129 RGD:1299066 NCBI chr 9:55,690,939...55,768,008
Ensembl chr 9:55,678,264...55,727,680
JBrowse link
visual phototransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARR3 arrestin 3 ISO RGD PMID:21824527, PMID:22074925 RGD:6893539, RGD:6893556 NCBI chr  X:54,725,034...54,730,920
Ensembl chr  X:54,718,323...54,730,852
JBrowse link
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:12087135 RGD:6893549 NCBI chr13:43,831,159...43,864,276
Ensembl chr13:43,831,163...43,864,276
JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 ISO RGD PMID:12087135 RGD:6893549 NCBI chr10:44,232,716...44,278,555
Ensembl chr10:44,234,004...44,260,746
JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:12087135 RGD:6893549 NCBI chr 2:58,574,552...58,641,631
Ensembl chr 2:58,574,552...58,640,812
JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 ISO RGD PMID:12087135 RGD:6893549 NCBI chr29:32,744,946...32,992,715
Ensembl chr29:32,749,389...32,893,077
JBrowse link
G GNAT1 G protein subunit alpha transducin 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chr20:39,128,244...39,133,280
Ensembl chr20:39,128,244...39,133,280
JBrowse link
G GNAT2 G protein subunit alpha transducin 2 ISO RGD PMID:22074925 RGD:6893539 NCBI chr 6:42,259,404...42,271,197
Ensembl chr 6:42,259,702...42,268,082
JBrowse link
G GNB1 G protein subunit beta 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chr 5:56,777,854...56,879,619
Ensembl chr 5:56,779,354...56,817,295
JBrowse link
G GNB3 G protein subunit beta 3 ISO RGD PMID:22074925 RGD:6893539 NCBI chr27:38,175,928...38,182,473
Ensembl chr27:38,175,931...38,181,763
JBrowse link
G GNB5 G protein subunit beta 5 ISO RGD PMID:22074925 RGD:6893539 NCBI chr30:17,835,051...17,876,443
Ensembl chr30:17,837,220...17,881,036
JBrowse link
G GNGT1 G protein subunit gamma transducin 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chr14:19,081,676...19,420,261
Ensembl chr14:19,415,510...19,420,255
JBrowse link
G GNGT2 G protein subunit gamma transducin 2 ISO RGD PMID:22074925 RGD:6893539 NCBI chr 9:25,369,751...25,374,812
Ensembl chr 9:25,369,753...25,372,655
JBrowse link
G GRK1 G protein-coupled receptor kinase 1 ISO RGD PMID:21903131 RGD:6893555 NCBI chr22:60,911,953...60,929,330
Ensembl chr22:60,911,953...60,926,146
JBrowse link
G GRK7 G protein-coupled receptor kinase 7 ISO RGD PMID:21903131 RGD:6893555 NCBI chr23:37,578,364...37,638,266
Ensembl chr23:37,606,969...37,636,458
JBrowse link
G GUCA1A guanylate cyclase activator 1A ISO RGD PMID:22074925 RGD:6893539 NCBI chr12:10,786,284...10,795,974
Ensembl chr12:10,788,424...10,795,442
JBrowse link
G GUCA1B guanylate cyclase activator 1B ISO RGD PMID:22074925 RGD:6893539 NCBI chr12:10,796,961...10,806,796
Ensembl chr12:10,797,921...10,834,237
JBrowse link
G GUCY2D guanylate cyclase 2D, retinal ISO RGD PMID:22074925 RGD:6893539 NCBI chr 5:32,844,033...32,859,263
Ensembl chr 5:32,844,033...32,857,687
JBrowse link
G GUCY2F guanylate cyclase 2F, retinal ISO RGD PMID:22074925 RGD:6893539 NCBI chr  X:82,648,673...82,751,394
Ensembl chr  X:82,649,601...82,751,394
JBrowse link
G OPN1LW opsin 1, medium wave sensitive ISO RGD PMID:21704730 RGD:6893536 NCBI chr  X:121,974,552...121,987,418
Ensembl chr  X:121,974,552...121,987,418
JBrowse link
G OPN1SW opsin 1, short wave sensitive ISO RGD PMID:21704730 RGD:6893536 NCBI chr14:7,865,370...7,869,516
Ensembl chr14:7,865,561...7,868,745
JBrowse link
G PDE6A phosphodiesterase 6A ISO RGD PMID:15224133 RGD:6893540 NCBI chr 4:59,103,965...59,163,857
Ensembl chr 4:59,103,945...59,163,857
JBrowse link
G PDE6B phosphodiesterase 6B ISO RGD PMID:15224133 RGD:6893540 NCBI chr 3:91,746,571...91,775,372
Ensembl chr 3:91,746,571...91,775,372
JBrowse link
G PDE6C phosphodiesterase 6C ISO RGD PMID:15224133 RGD:6893540 NCBI chr28:7,839,604...7,887,827
Ensembl chr28:7,839,847...7,887,776
JBrowse link
G PDE6G phosphodiesterase 6G ISO RGD PMID:15224133 RGD:6893540 NCBI chr 9:525,123...529,406
Ensembl chr 9:526,577...529,526
JBrowse link
G PDE6H phosphodiesterase 6H ISO RGD PMID:15224133 RGD:6893540 NCBI chr27:31,640,731...31,664,494
Ensembl chr27:31,640,737...31,664,401
JBrowse link
G RCVRN recoverin ISO RGD PMID:22074925 RGD:6893539 NCBI chr 5:34,323,580...34,330,667
Ensembl chr 5:34,323,576...34,330,667
JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:22074925 RGD:6893539 NCBI chr 9:14,809,977...14,905,299
Ensembl chr 9:14,809,864...14,905,197
JBrowse link
G RGS9BP regulator of G protein signaling 9 binding protein ISO RGD PMID:22074925 RGD:6893539 NCBI chr 1:119,316,799...119,322,856
Ensembl chr 1:119,321,909...119,322,625
JBrowse link
G RHO rhodopsin ISO RGD PMID:21704730 RGD:6893536 NCBI chr20:5,630,735...5,638,906 JBrowse link
G SAG S-antigen visual arrestin ISO RGD PMID:21824527, PMID:22074925 RGD:6893539, RGD:6893556 NCBI chr25:44,800,141...44,843,580
Ensembl chr25:44,812,362...44,843,579
JBrowse link
G SLC24A1 solute carrier family 24 member 1 ISO RGD PMID:18690016 RGD:6893550 NCBI chr30:29,967,762...29,996,762
Ensembl chr30:29,967,762...29,995,005
JBrowse link
G SLC24A2 solute carrier family 24 member 2 ISO RGD PMID:18690016 RGD:6893550 NCBI chr11:39,273,285...39,521,223
Ensembl chr11:39,278,370...39,519,222
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4016
    signaling pathway 1918
      signaling pathway pertinent to the brain and nervous system 229
        Reelin signaling pathway + 31
        altered signaling pathway pertinent to the brain and nervous system + 10
        gasotransmitter mediated signaling pathway + 0
        melatonin signaling pathway 0
        neuron-to-neuron signaling pathways + 129
        neurotrophic factor signaling pathway + 8
        sensory system signaling pathway + 71
        thyroid hormone signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.