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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:signaling pathway pertinent to the brain and nervous system
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Accession:PW:0000059 term browser browse the term
Definition:Those signaling pathways that are involved in or mediate the various aspects of nervous system and/or brain function.


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signaling pathway pertinent to the brain and nervous system term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16600505 RGD:1581409 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) ISO RGD PMID:17786266 RGD:8549506 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184
JBrowse link
G CHAT choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chr10:44,574,925...44,629,618 JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:23759942 RGD:8549590 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:19478075 RGD:8549592 NCBI chr10:115,776,236...116,026,221
Ensembl chr10:119,200,688...119,450,809
JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:22685433 RGD:8549594 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:22685433 RGD:8549594 NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225
JBrowse link
G RGS6 regulator of G protein signaling 6 ISO RGD PMID:22685433 RGD:8549594 NCBI chr14:52,511,846...53,146,872 JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chr10:44,630,006...44,632,419 JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chr2A:93,917,086...93,944,308
Ensembl chr2A:109,017,805...109,046,860
JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM2 cholinergic receptor muscarinic 2 ISO RGD PMID:23841840 RGD:8549585 NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796
JBrowse link
G CHRM4 cholinergic receptor muscarinic 4 ISO RGD PMID:23841840 RGD:8549585 NCBI chr11:46,342,384...46,350,366
Ensembl chr11:46,894,615...46,896,054
JBrowse link
G GNAI1 G protein subunit alpha i1 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 7:72,102,937...72,188,124
Ensembl chr 7:85,812,249...85,851,283
JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988
JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM1 cholinergic receptor muscarinic 1 ISO RGD PMID:23841840 RGD:8549585 NCBI chr11:58,261,476...58,274,685
Ensembl chr11:61,614,818...61,616,200
JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:23841840 RGD:8549585 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G CHRM5 cholinergic receptor muscarinic 5 ISO RGD PMID:23841840 RGD:8549585 NCBI chr15:12,478,656...12,575,512
Ensembl chr15:31,406,198...31,407,796
JBrowse link
G GNA11 G protein subunit alpha 11 ISO RGD PMID:23759942 RGD:8549590 NCBI chr19:2,120,398...2,149,161
Ensembl chr19:3,074,483...3,102,124
JBrowse link
G GNAQ G protein subunit alpha q ISO RGD PMID:23759942 RGD:8549590 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849
JBrowse link
G LOC100987065 guanine nucleotide-binding protein subunit alpha-14 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 9:47,196,338...47,423,388 JBrowse link
acetylcholine signaling pathway via nicotinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) ISO RGD PMID:17786266 RGD:8549506 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184
JBrowse link
G AGRN agrin ISO RGD PMID:23032192 RGD:8549508 Ensembl chr 1:936,000...966,808 JBrowse link
G CHAT choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chr10:44,574,925...44,629,618 JBrowse link
G CHRNA1 cholinergic receptor nicotinic alpha 1 subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr2B:62,022,498...62,039,370
Ensembl chr2B:179,476,677...179,504,763
JBrowse link
G CHRNA10 cholinergic receptor nicotinic alpha 10 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr11:3,543,450...3,552,036
Ensembl chr11:3,651,580...3,656,780
JBrowse link
G CHRNA2 cholinergic receptor nicotinic alpha 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 8:26,729,767...26,749,277
Ensembl chr 8:23,932,846...23,952,377
JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005
JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr15:57,493,730...57,530,463
Ensembl chr15:76,455,165...76,486,376
JBrowse link
G CHRNA6 cholinergic receptor nicotinic alpha 6 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 8:42,000,748...42,016,913
Ensembl chr 8:39,444,447...39,460,569
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194
JBrowse link
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 4:34,654,043...34,675,984
Ensembl chr 4:40,509,475...40,528,869
JBrowse link
G CHRNB1 cholinergic receptor nicotinic beta 1 subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr17:7,479,056...7,490,314
Ensembl chr17:7,465,229...7,476,099
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361
JBrowse link
G CHRNB3 cholinergic receptor nicotinic beta 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 8:41,947,062...41,987,159
Ensembl chr 8:39,391,001...39,429,926
JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr15:57,552,697...57,570,828
Ensembl chr15:76,515,455...76,532,712
JBrowse link
G CHRND cholinergic receptor nicotinic delta subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr2B:119,757,722...119,768,254
Ensembl chr2B:238,676,495...238,686,987
JBrowse link
G CHRNE cholinergic receptor nicotinic epsilon subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr17:4,944,046...4,950,288
Ensembl chr17:4,932,862...4,937,963
JBrowse link
G CHRNG cholinergic receptor nicotinic gamma subunit ISO RGD PMID:19126755, PMID:23032192 RGD:8549508, RGD:8549510 NCBI chr2B:119,770,636...119,779,332
Ensembl chr2B:238,689,935...238,696,526
JBrowse link
G DOK7 docking protein 7 ISO RGD PMID:23032192 RGD:8549508 NCBI chr 4:3,613,018...3,653,764
Ensembl chr 4:3,605,185...3,628,570
JBrowse link
G LRP4 LDL receptor related protein 4 ISO RGD PMID:23032192 RGD:8549508 NCBI chr11:46,808,090...46,868,649
Ensembl chr11:47,366,321...47,411,105
JBrowse link
G MUSK muscle associated receptor tyrosine kinase ISO RGD PMID:23032192 RGD:8549508 NCBI chr 9:81,814,766...81,947,341
Ensembl chr 9:109,980,748...110,107,480
JBrowse link
G RAPSN receptor associated protein of the synapse ISO RGD PMID:23032192 RGD:8549508 NCBI chr11:47,387,324...47,398,579
Ensembl chr11:47,940,530...47,951,667
JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chr10:44,630,006...44,632,419 JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chr2A:93,917,086...93,944,308
Ensembl chr2A:109,017,805...109,046,860
JBrowse link
altered clathrin-dependent synaptic vesicle endocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 ISO RGD PMID:25302295 RGD:10450553 NCBI chr 1:64,501,805...64,662,999
Ensembl chr 1:66,399,968...66,550,879
JBrowse link
G SYNJ1 synaptojanin 1 ISO RGD PMID:25302295 RGD:10450553 NCBI chr21:18,990,526...19,088,839
Ensembl chr21:32,368,949...32,466,994
JBrowse link
altered Reelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB1 DAB adaptor protein 1 ISO RGD PMID:12670697, PMID:12764038, PMID:16266828 RGD:1358468, RGD:2324967, RGD:727518 NCBI chr 1:56,279,089...57,529,881
Ensembl chr 1:58,005,136...58,286,708
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:12778121 RGD:2324970 NCBI chr 6:109,469,750...109,684,086
Ensembl chr 6:113,545,944...113,604,451
JBrowse link
G ITGA3 integrin subunit alpha 3 ISO RGD PMID:15583703 RGD:2325851 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245
JBrowse link
G ITGB1 integrin subunit beta 1 ISO RGD PMID:15583703 RGD:2325851 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031
JBrowse link
G LRP8 LDL receptor related protein 8 ISO RGD PMID:19846452 RGD:2324974 NCBI chr 1:52,515,534...52,600,390
Ensembl chr 1:54,114,909...54,199,452
JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 ISO RGD PMID:17330141 RGD:4107040 NCBI chr17:2,584,349...2,676,928
Ensembl chr17:2,590,007...2,680,994
JBrowse link
G PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 ISO RGD PMID:17330141 RGD:4107040 NCBI chr11:111,978,368...112,005,064
Ensembl chr11:115,911,803...115,944,351
JBrowse link
G PAFAH1B3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 ISO RGD PMID:17330141 RGD:4107040 NCBI chr19:39,184,734...39,190,522 JBrowse link
G RELN reelin ISO RGD PMID:12670697, PMID:12764038 RGD:1358468, RGD:727518 NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:18237558 RGD:2325284 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G VLDLR very low density lipoprotein receptor ISO RGD PMID:12764038 RGD:1358468 NCBI chr 9:2,428,639...2,463,796
Ensembl chr 9:2,621,199...2,653,980
JBrowse link
altered visual phototransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:20212494 RGD:8547536 NCBI chr 4:74,196,877...74,213,563
Ensembl chr 4:84,910,653...84,945,248
JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:20212494 RGD:8547536 NCBI chr16:38,160,056...38,249,474
Ensembl chr16:57,292,093...57,375,460
JBrowse link
G GUCA1B guanylate cyclase activator 1B ISO RGD PMID:20212494 RGD:8547536 NCBI chr 6:41,771,537...41,783,364
Ensembl chr 6:43,072,469...43,083,838
JBrowse link
G PDE6A phosphodiesterase 6A ISO RGD PMID:20212494 RGD:8547536 NCBI chr 5:145,283,505...145,369,596
Ensembl chr 5:151,294,041...151,375,832
JBrowse link
G PDE6G phosphodiesterase 6G ISO RGD PMID:20212494 RGD:8547536 NCBI chr17:76,105,827...76,122,750 JBrowse link
G RHO rhodopsin ISO RGD PMID:20212494 RGD:8547536 NCBI chr 3:126,586,510...126,593,028
Ensembl chr 3:133,938,419...133,944,928
JBrowse link
G SAG S-antigen visual arrestin ISO RGD PMID:20212494 RGD:8547536 NCBI chr2B:120,532,049...120,574,914
Ensembl chr2B:239,449,910...239,487,537
JBrowse link
auditory mechanotransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTG1 actin gamma 1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr17:75,965,911...75,968,822
Ensembl chr17:81,668,221...81,671,087
JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr 5:24,208,844...24,811,284
Ensembl chr 5:24,341,808...24,945,477
JBrowse link
G CDH23 cadherin related 23 ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr10:67,866,979...68,286,008
Ensembl chr10:70,434,801...70,810,240
JBrowse link
G ESPN espin ISO RGD PMID:19804752, PMID:20624897 RGD:8547667, RGD:8547669 NCBI chr 1:5,184,666...5,222,473 JBrowse link
G LOC100971960 unconventional myosin-XV ISO RGD PMID:19804752 RGD:8547667 NCBI chr17:32,661,499...32,723,320 JBrowse link
G MYO1C myosin IC ISO RGD PMID:19804752 RGD:8547667 NCBI chr17:1,446,506...1,475,634
Ensembl chr17:1,345,143...1,375,540
JBrowse link
G MYO3A myosin IIIA ISO RGD PMID:19804752 RGD:8547667 NCBI chr10:26,104,588...26,389,942
Ensembl chr10:26,469,742...26,754,989
JBrowse link
G MYO6 myosin VI ISO RGD PMID:20624897, PMID:22715884 RGD:8547669, RGD:8547672 NCBI chr 6:73,593,794...73,764,352
Ensembl chr 6:76,951,634...77,048,796
JBrowse link
G MYO7A myosin VIIA ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752
JBrowse link
G OTOF otoferlin ISO RGD PMID:22715884 RGD:8547672 NCBI chr2A:26,454,010...26,555,642
Ensembl chr2A:26,546,959...26,647,278
JBrowse link
G PCDH15 protocadherin related 15 ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr10:50,452,290...52,236,538
Ensembl chr10:52,666,969...53,536,611
JBrowse link
G PLS1 plastin 1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr 3:139,629,825...139,747,080
Ensembl chr 3:147,289,205...147,338,600
JBrowse link
G PLS3 plastin 3 ISO RGD PMID:20624897 RGD:8547669 NCBI chr  X:104,656,110...104,745,702
Ensembl chr  X:115,160,032...115,250,144
JBrowse link
G PTPRQ protein tyrosine phosphatase receptor type Q ISO RGD PMID:20624897 RGD:8547669 NCBI chr12:77,957,758...78,200,206
Ensembl chr12:81,068,545...81,310,857
JBrowse link
G SLC17A8 solute carrier family 17 member 8 ISO RGD PMID:22715884 RGD:8547672 NCBI chr12:97,935,177...98,001,240
Ensembl chr12:101,342,113...101,405,844
JBrowse link
G USH1C USH1 protein network component harmonin ISO RGD PMID:19804752, PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr11:17,548,501...17,598,923
Ensembl chr11:17,233,854...17,284,256
JBrowse link
G USH1G USH1 protein network component sans ISO RGD PMID:22177415 RGD:8547671 NCBI chr17:68,861,622...68,868,822
Ensembl chr17:74,419,769...74,424,794
JBrowse link
G USH2A usherin ISO RGD PMID:20624897 RGD:8547669 NCBI chr 1:191,193,130...191,994,664
Ensembl chr 1:196,048,086...196,850,216
JBrowse link
G WHRN whirlin ISO RGD PMID:19804752 RGD:8547667 NCBI chr 9:85,500,222...85,604,417
Ensembl chr 9:113,863,872...113,966,758
JBrowse link
brain-derived neurotrophic factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor ISO RGD PMID:23670594 RGD:11062158 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239
JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr12:66,992,207...67,107,313
Ensembl chr12:69,829,435...69,878,293
JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr17:69,265,307...69,352,835
Ensembl chr17:74,817,471...74,903,796
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678
JBrowse link
G SHC1 SHC adaptor protein 1 ISO RGD PMID:23670594 RGD:11062158 NCBI chr 1:130,310,778...130,323,001
Ensembl chr 1:133,920,532...133,929,008
JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:23670594 RGD:11062158 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883
JBrowse link
clathrin-dependent synaptic vesicle endocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP2A1 adaptor related protein complex 2 subunit alpha 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr19:46,779,196...46,820,055
Ensembl chr19:55,694,070...55,736,570
JBrowse link
G AP2A2 adaptor related protein complex 2 subunit alpha 2 ISO RGD PMID:22763746 RGD:10450547 NCBI chr11:945,170...1,034,860
Ensembl chr11:1,005,473...1,076,652
JBrowse link
G AP2B1 adaptor related protein complex 2 subunit beta 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr17:21,070,132...21,208,610
Ensembl chr17:21,363,121...21,501,721
JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 3:181,210,045...181,219,327
Ensembl chr 3:189,692,898...189,702,261
JBrowse link
G AP2S1 adaptor related protein complex 2 subunit sigma 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr19:43,827,907...43,840,682 JBrowse link
G CLTA clathrin light chain A ISO RGD PMID:22763746 RGD:10450547 NCBI chr 9:36,040,566...36,061,744
Ensembl chr 9:36,840,868...36,862,528
JBrowse link
G CLTB clathrin light chain B ISO RGD PMID:22763746 RGD:10450547 NCBI chr 5:171,689,273...171,713,198 JBrowse link
G CLTC clathrin heavy chain ISO RGD PMID:22763746 RGD:10450547 NCBI chr17:53,685,865...53,761,008
Ensembl chr17:58,529,750...58,603,636
JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 1:64,501,805...64,662,999
Ensembl chr 1:66,399,968...66,550,879
JBrowse link
G DNM1 dynamin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 9:99,324,385...99,376,262
Ensembl chr 9:128,004,508...128,044,690
JBrowse link
G DNM3 dynamin 3 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 1:147,339,773...147,916,513
Ensembl chr 1:151,049,346...151,615,808
JBrowse link
G DNMBP dynamin binding protein ISO RGD PMID:22763746 RGD:10450547 NCBI chr10:96,479,312...96,615,079
Ensembl chr10:99,972,725...100,066,397
JBrowse link
G EPN1 epsin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr19:52,722,107...52,743,321
Ensembl chr19:61,408,695...61,427,647
JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 1:50,598,692...50,763,585
Ensembl chr 1:52,097,387...52,223,533
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:22763746 RGD:10450547 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773
JBrowse link
G ITSN1 intersectin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr21:20,009,385...20,266,835
Ensembl chr21:33,457,081...33,625,248
JBrowse link
G PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma ISO RGD PMID:22763746 RGD:10450547 NCBI chr19:2,655,674...2,727,454
Ensembl chr19:3,606,279...3,641,933
JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 ISO RGD PMID:22763746 RGD:10450547 NCBI chr19:3,383,267...3,423,165
Ensembl chr19:4,329,750...4,340,121
JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 9:17,386,298...17,605,722
Ensembl chr 9:18,045,198...18,097,579
JBrowse link
G SH3GL3 SH3 domain containing GRB2 like 3, endophilin A3 ISO RGD PMID:22763746 RGD:10450547 NCBI chr15:61,988,584...62,153,543
Ensembl chr15:81,337,529...81,501,770
JBrowse link
G SNAP91 synaptosome associated protein 91 ISO RGD PMID:22763746 RGD:10450547 NCBI chr 6:81,441,792...81,600,505
Ensembl chr 6:84,720,850...84,874,407
JBrowse link
G SYNJ1 synaptojanin 1 ISO RGD PMID:22763746 RGD:10450547 NCBI chr21:18,990,526...19,088,839
Ensembl chr21:32,368,949...32,466,994
JBrowse link
dopamine signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK5 cyclin dependent kinase 5 ISO RGD PMID:21927600 RGD:11041163 NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499
JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 ISO RGD PMID:21927600 RGD:11041163 NCBI chr 5:144,919,775...144,977,105
Ensembl chr 5:150,929,420...150,985,912
JBrowse link
G DRD1 dopamine receptor D1 ISO heterodimer coupled to Galphaq RGD PMID:17314300, PMID:25671228 RGD:11041142, RGD:1625010 NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257
JBrowse link
G DRD2 dopamine receptor D2 ISO heterodimer coupled to Galphaq RGD PMID:12121979, PMID:16490190, PMID:17314300, PMID:25671228 RGD:11041142, RGD:1581445, RGD:1625010, RGD:1625068 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:16490190 RGD:1625068 NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403
JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:17314300 RGD:1625010 NCBI chr11:640,401...646,775 JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:25671228 RGD:11041142 NCBI chr 4:4,189,536...4,193,144
Ensembl chr 4:9,509,094...9,510,527
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr11:62,756,659...62,760,369
Ensembl chr11:66,068,007...66,071,611
JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr2A:28,758,176...28,809,561
Ensembl chr2A:28,862,083...28,889,401
JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chr12:108,288,158...108,311,128 JBrowse link
G PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B ISO RGD PMID:21303898, PMID:21927600 RGD:11041134, RGD:11041163 NCBI chr17:17,652,216...17,662,085
Ensembl chr17:17,868,965...17,878,120
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr 8:30,099,605...30,126,917
Ensembl chr 8:27,288,263...27,302,606
JBrowse link
G PPP2R3A protein phosphatase 2 regulatory subunit B''alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr 3:133,017,166...133,202,163
Ensembl chr 3:140,485,925...140,666,592
JBrowse link
G PPP2R5D protein phosphatase 2 regulatory subunit B'delta ISO RGD PMID:21927600 RGD:11041163 NCBI chr 6:42,576,759...42,604,609
Ensembl chr 6:43,871,915...43,899,183
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394
JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr10:69,984,241...70,043,352
Ensembl chr10:72,443,051...72,501,752
JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chr 8:21,690,598...21,791,335
Ensembl chr 8:18,629,261...18,729,995
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205
JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr 1:116,625,640...116,786,396
Ensembl chr 1:85,487,681...85,644,253
JBrowse link
G PRKACG protein kinase cAMP-activated catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chr 9:55,775,913...55,777,497
Ensembl chr 9:67,778,293...67,779,348
JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr11:18,758,285...18,822,845
Ensembl chr11:18,673,366...18,711,885
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16529858 RGD:1581410 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
dopamine signaling pathway via D1 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00308 NCBI chr 5:7,718,581...8,154,006
Ensembl chr 5:7,540,790...7,975,853
JBrowse link
G ADCY5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chr 3:120,380,094...120,545,725
Ensembl chr 3:127,283,921...127,446,508
JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:21303898 RGD:11041134 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB
RGD
PMID:21303898 RGD:11041134, SMP:00308 NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257
JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 4:4,189,536...4,193,144
Ensembl chr 4:9,509,094...9,510,527
JBrowse link
G GNAL G protein subunit alpha L ISO RGD PMID:24144882 RGD:11041135 NCBI chr18:2,420,578...2,615,947 JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00308 NCBI chr 1:490,415...596,826
Ensembl chr 1:1,647,340...1,701,614
JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00308 NCBI chr 1:66,941,315...67,071,442
Ensembl chr 1:68,901,264...68,903,487
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr22:6,579,664...6,789,846
Ensembl chr22:24,353,533...24,509,560
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr10:115,776,236...116,026,221
Ensembl chr10:119,200,688...119,450,809
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 5:172,704,978...172,744,907
Ensembl chr 5:179,790,662...179,807,410
JBrowse link
G LOC100990650 guanine nucleotide-binding protein G(s) subunit alpha ISO SMPDB SMP:00308 NCBI chr20:55,190,607...55,262,245 JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00308 NCBI chr 1:116,625,640...116,786,396
Ensembl chr 1:85,487,681...85,644,253
JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225
JBrowse link
G RGS7 regulator of G protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:216,329,373...216,919,898
Ensembl chr 1:221,313,924...221,899,627
JBrowse link
G RGS7BP regulator of G protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chr 5:49,385,866...49,494,601
Ensembl chr 5:51,040,699...51,144,406
JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chr17:59,085,707...59,176,368
Ensembl chr17:64,262,585...64,389,559
JBrowse link
dopamine signaling pathway via D2 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chr 3:120,380,094...120,545,725
Ensembl chr 3:127,283,921...127,446,508
JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:21303898 RGD:11041134 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403
JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr11:640,401...646,775 JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:24831693 RGD:11041136 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988
JBrowse link
G GNAO1 G protein subunit alpha o1 ISO RGD PMID:24831693 RGD:11041136 NCBI chr16:36,473,852...36,643,789
Ensembl chr16:55,606,920...55,776,619
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898, PMID:23940634 RGD:11041134, RGD:13792715 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr22:6,579,664...6,789,846
Ensembl chr22:24,353,533...24,509,560
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr10:115,776,236...116,026,221
Ensembl chr10:119,200,688...119,450,809
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 5:172,704,978...172,744,907
Ensembl chr 5:179,790,662...179,807,410
JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225
JBrowse link
G RGS7 regulator of G protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:216,329,373...216,919,898
Ensembl chr 1:221,313,924...221,899,627
JBrowse link
G RGS7BP regulator of G protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chr 5:49,385,866...49,494,601
Ensembl chr 5:51,040,699...51,144,406
JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chr17:59,085,707...59,176,368
Ensembl chr17:64,262,585...64,389,559
JBrowse link
epinephrine signaling pathway via adrenergic receptor beta term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19110970 RGD:4140391 NCBI chr10:110,642,491...110,646,595 JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:19110970 RGD:4140391 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:18268361, PMID:19229505 RGD:4140419, RGD:5135529 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:18268361, PMID:19229505 RGD:4140419, RGD:5135529 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:19110970, PMID:19229505 RGD:4140391, RGD:5135529 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:19110970, PMID:19229505 RGD:4140391, RGD:5135529 NCBI chr10:115,776,236...116,026,221
Ensembl chr10:119,200,688...119,450,809
JBrowse link
G LOC100990650 guanine nucleotide-binding protein G(s) subunit alpha ISO RGD PMID:19110970 RGD:4140391 NCBI chr20:55,190,607...55,262,245 JBrowse link
G SNX13 sorting nexin 13 ISO RGD PMID:17173929 RGD:4140388 NCBI chr 7:18,444,092...18,593,950
Ensembl chr 7:17,749,772...17,920,085
JBrowse link
excitatory synaptic transmission pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISO RGD PMID:17314300 RGD:1625010 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:17314300 RGD:1625010 NCBI chr11:640,401...646,775 JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:16477151 RGD:1642190 NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16477151 RGD:1642190 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:16477151 RGD:1642190 NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799
JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO RGD PMID:16477151 RGD:1642190 NCBI chr 9:72,773,866...72,943,790
Ensembl chr 9:100,767,715...100,941,323
JBrowse link
G KCND1 potassium voltage-gated channel subfamily D member 1 ISO RGD PMID:16141270 RGD:1581430 NCBI chr  X:41,258,803...41,270,036
Ensembl chr  X:49,115,933...49,127,030
JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO RGD PMID:16141270 RGD:1581430 NCBI chr 7:112,277,018...112,751,896
Ensembl chr 7:124,966,816...125,437,430
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO RGD PMID:16141270 RGD:1581430 NCBI chr 1:114,433,203...114,651,894
Ensembl chr 1:125,696,907...125,909,814
JBrowse link
Inhibitory synaptic transmission pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRA1 glycine receptor alpha 1 ISO RGD PMID:14749434 RGD:1598573 NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567
JBrowse link
G GLRB glycine receptor beta ISO RGD PMID:14749434 RGD:1598573 NCBI chr 4:149,422,654...149,518,669
Ensembl chr 4:161,236,610...161,333,035
JBrowse link
G GPHN gephyrin ISO RGD PMID:14976213 RGD:1300220 NCBI chr14:47,081,527...47,755,182
Ensembl chr14:66,137,166...66,634,550
JBrowse link
kallikrein-kinin cascade pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:16177542 RGD:7401223 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr14:76,885,923...76,894,456 JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:16177542 RGD:7401223 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253
JBrowse link
G CPM carboxypeptidase M ISO RGD PMID:16177542 RGD:7401223 NCBI chr12:66,367,023...66,445,801
Ensembl chr12:69,147,579...69,225,283
JBrowse link
G CPN1 carboxypeptidase N subunit 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr10:96,647,273...96,689,346
Ensembl chr10:100,130,688...100,171,687
JBrowse link
G F12 coagulation factor XII ISO RGD PMID:16177542 RGD:7401223 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485
JBrowse link
G KLK1 kallikrein 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr19:47,784,368...47,789,004
Ensembl chr19:56,677,579...56,682,216
JBrowse link
G KLKB1 kallikrein B1 ISO RGD PMID:16177542, PMID:18396440 RGD:7401223, RGD:7401224 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300
JBrowse link
G KNG1 kininogen 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149
JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:16177542 RGD:7401223 NCBI chr 3:152,085,694...152,240,148
Ensembl chr 3:160,197,566...160,292,119
JBrowse link
G PRCP prolylcarboxypeptidase ISO RGD PMID:18396440 RGD:7401224 NCBI chr11:77,890,115...77,967,056
Ensembl chr11:81,502,658...81,578,361
JBrowse link
G SERPINA4 serpin family A member 4 ISO RGD PMID:16177542 RGD:7401223 NCBI chr14:75,185,501...75,194,061
Ensembl chr14:94,517,341...94,525,820
JBrowse link
G SERPING1 serpin family G member 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr11:52,838,502...52,855,781
Ensembl chr11:56,309,686...56,326,639
JBrowse link
G XPNPEP1 X-prolyl aminopeptidase 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr10:106,457,390...106,516,111
Ensembl chr10:109,908,285...109,967,094
JBrowse link
G XPNPEP2 X-prolyl aminopeptidase 2 ISO RGD PMID:16177542 RGD:7401223 NCBI chr  X:118,869,083...118,900,639
Ensembl chr  X:129,165,882...129,197,347
JBrowse link
kinin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 ISO RGD PMID:21145390 RGD:7411621 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:21145390 RGD:7411621 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:15734727, PMID:16177542 RGD:7401223, RGD:7401225 NCBI chr14:76,885,923...76,894,456 JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:15734727, PMID:16177542 RGD:7401223, RGD:7401225 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO RGD PMID:15734727 RGD:7401225 NCBI chr 4:3,106,064...3,181,270
Ensembl chr 4:3,008,126...3,083,094
JBrowse link
G KNG1 kininogen 1 ISO RGD PMID:16177542 RGD:7401223 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149
JBrowse link
long term depression term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16904707, PMID:17655746 RGD:1642204, RGD:1642207 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:17329210 RGD:1641844 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
long term potentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11282364 RGD:1582105 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G EGR1 early growth response 1 ISO RGD PMID:16930406 RGD:1626499 NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260
JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 ISO RGD PMID:10580501 RGD:1642498 NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:16904707, PMID:17655746 RGD:1642204, RGD:1642207 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:16904707, PMID:17655746, PMID:20164351 RGD:1642204, RGD:1642207, RGD:2325882 NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799
JBrowse link
G KCND1 potassium voltage-gated channel subfamily D member 1 ISO RGD PMID:16141270 RGD:1581430 NCBI chr  X:41,258,803...41,270,036
Ensembl chr  X:49,115,933...49,127,030
JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO RGD PMID:16141270 RGD:1581430 NCBI chr 7:112,277,018...112,751,896
Ensembl chr 7:124,966,816...125,437,430
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO RGD PMID:16141270 RGD:1581430 NCBI chr 1:114,433,203...114,651,894
Ensembl chr 1:125,696,907...125,909,814
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO RGD PMID:11282364 RGD:1582105 NCBI chr 5:92,247,060...92,348,900
Ensembl chr 5:97,842,110...97,893,876
JBrowse link
G PTK2 protein tyrosine kinase 2 ISO RGD PMID:12764094 RGD:2292620 NCBI chr 8:137,330,777...137,677,306
Ensembl chr 8:140,412,773...140,684,898
JBrowse link
nerve growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO RGD PMID:15728722 RGD:1581104 NCBI chr2A:39,019,046...39,162,248
Ensembl chr2A:39,773,760...39,911,961
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:15546918 RGD:1580675 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
neuron-to-neuron signaling pathway via the chemical synapse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNJ12 potassium inwardly rectifying channel subfamily J member 12 ISO RGD PMID:15936845 RGD:1581471 NCBI chr17:30,190,240...30,233,740 JBrowse link
G KCNJ14 potassium inwardly rectifying channel subfamily J member 14 ISO RGD PMID:15936845 RGD:1581471 NCBI chr19:45,456,082...45,469,017
Ensembl chr19:54,055,580...54,060,204
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO RGD PMID:15936845 RGD:1581471 NCBI chr17:64,097,908...64,112,914
Ensembl chr17:69,487,846...69,489,129
JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO RGD PMID:15936845 RGD:1581471 NCBI chr22:19,341,699...19,370,666
Ensembl chr22:37,163,760...37,165,097
JBrowse link
neuron-to-neuron signaling pathway via the electrical synapse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PANX1 pannexin 1 ISO RGD PMID:14597722 RGD:1299639 NCBI chr11:89,142,686...89,295,972
Ensembl chr11:92,628,760...92,685,109
JBrowse link
G PANX2 pannexin 2 ISO RGD PMID:14597722 RGD:1299639 NCBI chr22:30,398,717...30,408,358
Ensembl chr22:49,404,624...49,408,045
JBrowse link
Reelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200062 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 ISO PID PID:200062 NCBI chr 1:131,282,514...131,326,535
Ensembl chr 1:135,112,040...135,159,299
JBrowse link
G CBL Cbl proto-oncogene ISO PID PID:200062 NCBI chr11:114,044,996...114,149,204
Ensembl chr11:117,973,187...118,074,671
JBrowse link
G CDK5 cyclin dependent kinase 5 ISO PID PID:200062 NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 ISO PID PID:200062 NCBI chr17:24,285,069...24,289,311
Ensembl chr17:24,577,537...24,579,232
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO PID PID:200062 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858
JBrowse link
G DAB1 DAB adaptor protein 1 ISO PID
RGD
PMID:12670697, PMID:12764038, PMID:16266828 PID:200062, RGD:1358468, RGD:2324967, RGD:727518 NCBI chr 1:56,279,089...57,529,881
Ensembl chr 1:58,005,136...58,286,708
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO PID
RGD
PMID:12778121 PID:200062, RGD:2324970 NCBI chr 6:109,469,750...109,684,086
Ensembl chr 6:113,545,944...113,604,451
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO RGD PMID:18237558 RGD:2325284 NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO PID
RGD
PMID:18237558 PID:200062, RGD:2325284 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO PID
RGD
PMID:18237558 PID:200062, RGD:2325284 NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO PID PID:200062 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G ITGA3 integrin subunit alpha 3 ISO PID
RGD
PMID:15583703 PID:200062, RGD:2325851 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245
JBrowse link
G ITGB1 integrin subunit beta 1 ISO PID
RGD
PMID:15583703 PID:200062, RGD:2325851 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031
JBrowse link
G LRP8 LDL receptor related protein 8 ISO PID
RGD
PMID:19846452 PID:200062, RGD:2324974 NCBI chr 1:52,515,534...52,600,390
Ensembl chr 1:54,114,909...54,199,452
JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 ISO PID PID:200062 NCBI chr 4:3,663,649...3,683,450
Ensembl chr 4:3,646,179...3,666,098
JBrowse link
G MAP1B microtubule associated protein 1B ISO PID PID:200062 NCBI chr 5:43,102,739...43,204,978
Ensembl chr 5:43,701,530...43,803,393
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO PID PID:200062 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 ISO PID PID:200062 NCBI chr11:60,956,880...60,973,972
Ensembl chr11:64,291,635...64,307,737
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO PID PID:200062 NCBI chr10:45,806,748...45,936,362 JBrowse link
G MAPT microtubule associated protein tau ISO PID PID:200062 NCBI chr17:11,373,220...11,506,669
Ensembl chr17:11,458,159...11,523,129
JBrowse link
G NCK2 NCK adaptor protein 2 ISO PID PID:200062 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 ISO PID
RGD
PMID:17330141 PID:200062, RGD:4107040 NCBI chr17:2,584,349...2,676,928
Ensembl chr17:2,590,007...2,680,994
JBrowse link
G PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 ISO RGD PMID:17330141 RGD:4107040 NCBI chr11:111,978,368...112,005,064
Ensembl chr11:115,911,803...115,944,351
JBrowse link
G PAFAH1B3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 ISO RGD PMID:17330141 RGD:4107040 NCBI chr19:39,184,734...39,190,522 JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200062 NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID
RGD
PMID:17167084 PID:200062, RGD:4108507 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO PID PID:200062 NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO PID PID:200062 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664
JBrowse link
G RELN reelin ISO PID
RGD
PMID:12670697, PMID:12893944 PID:200062, RGD:1358346, RGD:727518 NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:18237558 RGD:2325284 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G VLDLR very low density lipoprotein receptor ISO PID
RGD
PMID:12670697, PMID:12764038, PMID:12893944 PID:200062, RGD:1358346, RGD:1358468, RGD:727518 NCBI chr 9:2,428,639...2,463,796
Ensembl chr 9:2,621,199...2,653,980
JBrowse link
serotonin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100967334 G-protein coupled estrogen receptor 1 ISO RGD PMID:19095043 RGD:39939084 NCBI chr 7:1,245,873...1,251,915 JBrowse link
serotonin signaling pathway via receptors engaging G alphas protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 5:7,718,581...8,154,006
Ensembl chr 5:7,540,790...7,975,853
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130
JBrowse link
G ESR1 estrogen receptor 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 1:490,415...596,826
Ensembl chr 1:1,647,340...1,701,614
JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 1:66,941,315...67,071,442
Ensembl chr 1:68,901,264...68,903,487
JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 ISO SMPDB SMP:00309 NCBI chr 5:143,918,925...144,208,779
Ensembl chr 5:149,889,969...150,108,357
JBrowse link
G HTR6 5-hydroxytryptamine receptor 6 ISO SMPDB SMP:00312 NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO SMPDB SMP:00311 NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158
JBrowse link
G LOC100990650 guanine nucleotide-binding protein G(s) subunit alpha ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr20:55,190,607...55,262,245 JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr11:62,756,659...62,760,369
Ensembl chr11:66,068,007...66,071,611
JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00309, SMP:00311, SMP:00312 NCBI chr 1:116,625,640...116,786,396
Ensembl chr 1:85,487,681...85,644,253
JBrowse link
synaptic vesicle exocytosis - neurotransmitter release pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:8247129 RGD:1299066 NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152
JBrowse link
visual phototransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARR3 arrestin 3 ISO RGD PMID:21824527, PMID:22074925 RGD:6893539, RGD:6893556 NCBI chr  X:59,536,796...59,550,274
Ensembl chr  X:69,596,163...69,609,624
JBrowse link
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:12087135 RGD:6893549 NCBI chr 4:74,196,877...74,213,563
Ensembl chr 4:84,910,653...84,945,248
JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 ISO RGD PMID:12087135 RGD:6893549 NCBI chr2A:100,911,053...100,962,278
Ensembl chr2A:99,259,808...99,308,517
JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:12087135 RGD:6893549 NCBI chr16:38,160,056...38,249,474
Ensembl chr16:57,292,093...57,375,460
JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 ISO RGD PMID:12087135 RGD:6893549 NCBI chr 8:83,269,589...83,439,999
Ensembl chr 8:85,238,043...85,407,059
JBrowse link
G GNAT1 G protein subunit alpha transducin 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chr 3:50,119,267...50,126,131
Ensembl chr 3:51,354,472...51,360,568
JBrowse link
G GNAT2 G protein subunit alpha transducin 2 ISO RGD PMID:22074925 RGD:6893539 NCBI chr 1:111,980,855...111,990,686
Ensembl chr 1:111,208,510...111,225,808
JBrowse link
G GNB1 G protein subunit beta 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chr 1:490,415...596,826
Ensembl chr 1:1,647,340...1,701,614
JBrowse link
G GNB3 G protein subunit beta 3 ISO RGD PMID:22074925 RGD:6893539 NCBI chr12:6,971,854...6,979,214
Ensembl chr12:6,883,280...6,890,692
JBrowse link
G GNB5 G protein subunit beta 5 ISO RGD PMID:22074925 RGD:6893539 NCBI chr15:31,061,310...31,122,427
Ensembl chr15:49,388,026...49,452,123
JBrowse link
G GNGT1 G protein subunit gamma transducin 1 ISO RGD PMID:22074925 RGD:6893539 NCBI chr 7:85,839,639...85,859,844
Ensembl chr 7:99,446,623...99,451,185
JBrowse link
G GNGT2 G protein subunit gamma transducin 2 ISO RGD PMID:22074925 RGD:6893539 NCBI chr17:8,382,933...8,398,544 JBrowse link
G GRK1 G protein-coupled receptor kinase 1 ISO RGD PMID:21903131 RGD:6893555 NCBI chr13:94,816,045...94,838,509
Ensembl chr13:113,867,002...113,885,610
JBrowse link
G GRK7 G protein-coupled receptor kinase 7 ISO RGD PMID:21903131 RGD:6893555 NCBI chr 3:138,806,056...138,847,891
Ensembl chr 3:146,403,211...146,443,474
JBrowse link
G GUCA1ANB GUCA1A neighbor ISO RGD PMID:22074925 RGD:6893539 NCBI chr 6:41,743,396...41,751,883 JBrowse link
G GUCA1B guanylate cyclase activator 1B ISO RGD PMID:22074925 RGD:6893539 NCBI chr 6:41,771,537...41,783,364
Ensembl chr 6:43,072,469...43,083,838
JBrowse link
G GUCY2D guanylate cyclase 2D, retinal ISO RGD PMID:22074925 RGD:6893539 NCBI chr17:8,037,301...8,051,478
Ensembl chr17:8,023,519...8,036,065
JBrowse link
G GUCY2F guanylate cyclase 2F, retinal ISO RGD PMID:22074925 RGD:6893539 NCBI chr  X:98,481,609...98,590,680
Ensembl chr  X:108,952,200...109,061,441
JBrowse link
G OPN1SW opsin 1, short wave sensitive ISO RGD PMID:21704730 RGD:6893536 NCBI chr 7:120,724,363...120,727,649
Ensembl chr 7:133,246,131...133,251,464
JBrowse link
G PDE6A phosphodiesterase 6A ISO RGD PMID:15224133 RGD:6893540 NCBI chr 5:145,283,505...145,369,596
Ensembl chr 5:151,294,041...151,375,832
JBrowse link
G PDE6C phosphodiesterase 6C ISO RGD PMID:15224133 RGD:6893540 NCBI chr10:90,361,003...90,414,169
Ensembl chr10:93,871,704...93,924,654
JBrowse link
G PDE6G phosphodiesterase 6G ISO RGD PMID:15224133 RGD:6893540 NCBI chr17:76,105,827...76,122,750 JBrowse link
G PDE6H phosphodiesterase 6H ISO RGD PMID:15224133 RGD:6893540 NCBI chr12:14,890,192...14,984,542
Ensembl chr12:15,372,413...15,381,249
JBrowse link
G RCVRN recoverin ISO RGD PMID:22074925 RGD:6893539 NCBI chr17:41,747,255...41,759,074
Ensembl chr17:46,490,605...46,502,962
JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:22074925 RGD:6893539 NCBI chr17:59,085,707...59,176,368
Ensembl chr17:64,262,585...64,389,559
JBrowse link
G RGS9BP regulator of G protein signaling 9 binding protein ISO RGD PMID:22074925 RGD:6893539 NCBI chr19:29,595,159...29,597,612
Ensembl chr19:38,343,663...38,344,370
JBrowse link
G RHO rhodopsin ISO RGD PMID:21704730 RGD:6893536 NCBI chr 3:126,586,510...126,593,028
Ensembl chr 3:133,938,419...133,944,928
JBrowse link
G SAG S-antigen visual arrestin ISO RGD PMID:21824527, PMID:22074925 RGD:6893539, RGD:6893556 NCBI chr2B:120,532,049...120,574,914
Ensembl chr2B:239,449,910...239,487,537
JBrowse link
G SLC24A1 solute carrier family 24 member 1 ISO RGD PMID:18690016 RGD:6893550 NCBI chr15:44,552,886...44,597,640
Ensembl chr15:62,831,987...62,882,431
JBrowse link
G SLC24A2 solute carrier family 24 member 2 ISO RGD PMID:18690016 RGD:6893550 NCBI chr 9:19,317,132...19,593,503
Ensembl chr 9:19,814,244...20,249,225
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4036
    signaling pathway 1929
      signaling pathway pertinent to the brain and nervous system 228
        Reelin signaling pathway + 32
        altered signaling pathway pertinent to the brain and nervous system + 11
        gasotransmitter mediated signaling pathway + 0
        melatonin signaling pathway 0
        neuron-to-neuron signaling pathways + 131
        neurotrophic factor signaling pathway + 8
        sensory system signaling pathway + 67
        thyroid hormone signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.