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Pathways

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).

Term:tyrosine metabolic pathway
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Accession:PW:0000052 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of tyrosine - a non-essential amino acid produced from phenylalanine and a precursor of thyroid hormones, catecholamines and melanin. Along with phenylalanine and tryptophan, it is one of the three aromatic amino acids.
Synonyms:related_synonym: tyrosine metabolic process



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tyrosine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide IEA KEGG rno:00350 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide IEA KEGG rno:00350 NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) IEA KEGG rno:00350 NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:229,576,636...229,607,914
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide IEA KEGG rno:00350 NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:229,421,252...229,436,691
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 IEA KEGG rno:00350 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 IEA KEGG rno:00350 NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538
JBrowse link
G Aoc1 amine oxidase, copper containing 1 ISO SMPDB SMP:00006 NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:79,143,126...79,162,704
JBrowse link
G Aoc3 amine oxidase, copper containing 3 IEA KEGG rno:00350 NCBI chr10:86,773,018...86,780,961 JBrowse link
G Aox1 aldehyde oxidase 1 IEA KEGG rno:00350 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
JBrowse link
G Aox2 aldehyde oxidase 2 IEA KEGG rno:00350 NCBI chr 9:59,828,403...59,916,175
Ensembl chr 9:67,322,598...67,410,363
JBrowse link
G Comt catechol-O-methyltransferase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
JBrowse link
G Dbh dopamine beta-hydroxylase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316
JBrowse link
G Dct dopachrome tautomerase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr15:101,469,159...101,508,029
Ensembl chr15:101,469,159...101,508,029
JBrowse link
G Ddc dopa decarboxylase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806
JBrowse link
G Fah fumarylacetoacetate hydrolase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:147,957,935...147,981,046
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 IEA KEGG rno:00350 NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,180,431...9,206,111
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase ISO SMPDB SMP:00006 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:16,598,087...16,617,356
JBrowse link
G Hemk1 HemK methyltransferase family member 1 IEA KEGG rno:00350 NCBI chr 8:116,878,317...116,889,342
Ensembl chr 8:116,878,318...116,888,873
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:76,592,204...76,643,767
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:39,042,238...39,053,612
JBrowse link
G Lao1 L-amino acid oxidase 1 IEA KEGG rno:00350 NCBI chr 5:132,573,698...132,583,591
Ensembl chr 5:137,859,033...137,868,917
JBrowse link
G Maoa monoamine oxidase A IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631
JBrowse link
G Maob monoamine oxidase B IEA KEGG rno:00350 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375
JBrowse link
G Mettl6 methyltransferase 6, tRNA N3-cytidine IEA KEGG rno:00350 NCBI chr16:6,667,971...6,705,385
Ensembl chr16:6,689,248...6,705,359
JBrowse link
G Mif macrophage migration inhibitory factor IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr10:83,881,211...83,882,849
Ensembl chr10:83,881,185...83,882,849
JBrowse link
G Tat tyrosine aminotransferase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482
JBrowse link
G Th tyrosine hydroxylase IEA KEGG rno:00350 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
JBrowse link
G Tpo thyroid peroxidase IEA KEGG rno:00350 NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793
JBrowse link
G Tyr tyrosinase IEA
ISO
KEGG
SMPDB
SMP:00006 rno:00350 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
JBrowse link
G Tyrp1 tyrosinase-related protein 1 IEA KEGG rno:00350 NCBI chr 5:100,327,111...100,345,657
Ensembl chr 5:100,327,125...100,345,657
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      amino acid metabolic pathway 308
        amino acid metabolic pathway (KEGG) 266
          tyrosine metabolic pathway 34
            melanin biosynthetic pathway 0
            tyrosine biosynthetic pathway 0
            tyrosine degradation pathway 0
paths to the root