Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:fatty acid biosynthetic pathway
go back to main search page
Accession:PW:0000029 term browser browse the term
Definition:Acetyl-CoA, the starting material for fatty acid biosynthesis, can be derived from amino acid and lipid degradation or the oxidative decarboxylation of pyruvate. Fatty acid biosynthesis involves the condensation of C2 units; it requires seven enzymatic reactions which are carried out by the multifunctional enzyme fatty acid synthase.
Synonyms:related_synonym: fatty acid biosynthetic process
 alt_id: PW:0000030
View Interactive Diagram


show annotations for term's descendants           Sort by:
fatty acid biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha IEA
ISO
IDA 		KEGG
SMPDB
RGD		 PMID:11735100 PMID:17882277 SMP:00456 rno:00061, RGD:2317316, RGD:2317309 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Acacb acetyl-CoA carboxylase beta IEA KEGG rno:00061 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214 		JBrowse link
G Acly ATP citrate lyase ISO
IDA 		RGD PMID:17882277 PMID:11735100 RGD:2317309, RGD:2317316 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631 		JBrowse link
G Fasn fatty acid synthase ISO
IEA
IMP 		SMPDB
KEGG
RGD		 PMID:19181734 PMID:15715522 PMID:17882277 SMP:00456 rno:00061, RGD:2317204, RGD:2317317, RGD:2317309 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Mcat malonyl-CoA-acyl carrier protein transacylase IEA KEGG rno:00061 NCBI chr 7:116,573,632...116,585,767
Ensembl chr 7:116,573,368...116,584,562 		JBrowse link
G Olah oleoyl-ACP hydrolase IEA KEGG rno:00061 NCBI chr17:79,786,441...79,811,692
Ensembl chr17:79,786,832...79,811,688 		JBrowse link
G Oxsm 3-oxoacyl-ACP synthase, mitochondrial IEA KEGG rno:00061 NCBI chr15:11,641,177...11,645,370
Ensembl chr15:11,634,473...11,683,429 		JBrowse link
fatty acid elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 IEA
ISO 		KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 IEA
ISO 		KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEA KEGG rno:00062 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha IEA
ISO 		KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta IEA
ISO 		KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO SMPDB SMP:00054 NCBI chr  X:24,568,551...24,571,012
Ensembl chr  X:24,568,551...24,574,681 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase IEA
ISO 		KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 5:149,313,765...149,339,964
Ensembl chr 5:149,313,774...149,342,825 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 5:140,406,318...140,427,201
Ensembl chr 5:140,406,214...140,427,200 		JBrowse link
G Ppt2 palmitoyl-protein thioesterase 2 IEA KEGG rno:00062 NCBI chr20:4,117,088...4,137,382
Ensembl chr20:4,127,164...4,137,381 		JBrowse link
unsaturated fatty acid biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A IEA KEGG rno:01040 NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B IEA KEGG rno:01040 NCBI chr 8:127,750,771...127,759,589
Ensembl chr 8:127,750,743...127,759,569 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 IEA KEGG rno:01040 NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 IEA KEGG rno:01040 NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502 		JBrowse link
G Acot3 acyl-CoA thioesterase 3 IEA KEGG rno:01040 NCBI chr 6:109,413,617...109,419,840
Ensembl chr 6:109,413,534...109,421,427
Ensembl chr 6:109,413,534...109,421,427 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 IEA KEGG rno:01040 NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138 		JBrowse link
G Acot5 acyl-CoA thioesterase 5 IEA KEGG rno:01040 NCBI chr 6:109,433,062...109,439,846
Ensembl chr 6:109,453,391...109,461,035
Ensembl chr 6:109,453,391...109,461,035 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 IEA KEGG rno:01040 NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033 		JBrowse link
G Acox1 acyl-CoA oxidase 1 IEA KEGG rno:01040 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136 		JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl IEA KEGG rno:01040 NCBI chr14:79,358,604...79,405,160
Ensembl chr14:79,302,042...79,400,881 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase IEA KEGG rno:01040 NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 IEA KEGG rno:01040 NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 IEA KEGG rno:01040 NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 IEA KEGG rno:01040 NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549 		JBrowse link
G Fads1 fatty acid desaturase 1 IEA KEGG rno:01040 NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615 		JBrowse link
G Fads2 fatty acid desaturase 2 IEA KEGG rno:01040 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 IEA KEGG rno:01040 NCBI chr17:81,992,284...82,014,676
Ensembl chr17:81,992,292...82,014,592 		JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 IEA KEGG rno:01040 NCBI chr11:79,175,470...79,268,975
Ensembl chr11:79,175,482...79,268,126 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha IEA KEGG rno:01040 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 IEA KEGG rno:01040 NCBI chr 3:100,445,393...100,568,898
Ensembl chr 3:100,445,400...100,568,938 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase IEA KEGG rno:01040 NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806 		JBrowse link
G Scd stearoyl-CoA desaturase IEA KEGG rno:01040 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 IEA KEGG rno:01040 NCBI chr 1:253,118,377...253,131,436
Ensembl chr 1:253,117,655...253,128,874 		JBrowse link
G Scd4 stearoyl-coenzyme A desaturase 4 IEA KEGG rno:01040 NCBI chr 1:253,152,519...253,165,216
Ensembl chr 1:253,139,826...253,165,235 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase IEA KEGG rno:01040 NCBI chr19:41,431,422...41,472,880
Ensembl chr19:41,446,071...41,474,432 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1852
      lipid metabolic pathway 488
        fatty acid metabolic pathway 191
          fatty acid biosynthetic pathway 40
            fatty acid elongation pathway 9
            fatty-acyl-CoA biosynthetic pathway 0
            unsaturated fatty acid biosynthetic pathway + 25
            wax biosynthetic pathway 0
paths to the root