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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased tubuloglomerular feedback response
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Accession:MP:0031404 term browser browse the term
Definition:enhancement of the blood flow control mechanism that is operated in the juxtaglomerular apparatus of the kidney and involved in renal autoregulation by limiting changes in the glomerular filtration rate. TGF responds to changes in the concentration of NaCl in the tubular fluid at the level of the macula densa
Synonyms:exact_synonym: enhanced TGF response;   enhanced tubuloglomerular feedback response;   improved TGF response;   improved tubuloglomerular feedback response;   increased TGF response



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increased tubuloglomerular feedback response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ets1 ETS proto-oncogene 1, transcription factor induces IMP compared to wild type littermate RGD PMID:31932071 RGD:150429812 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G Ets1em1Mcwi v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); zinc finger nuclease induced mutant 1, Medical College of Wisconsin induces IMP compared to wild type littermate RGD PMID:31932071 RGD:150429812

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  mammalian phenotype 5402
    renal/urinary system phenotype 649
      abnormal renal/urinary system physiology 478
        abnormal kidney physiology 142
          abnormal tubuloglomerular feedback response 14
            increased tubuloglomerular feedback response 3
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