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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal circulating CSF3 level
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Accession:MP:0031243 term browser browse the term
Definition:deviation from the normal blood levels of CSF3, a cytokine glycoprotein produced by endothelium, macrophages and other immune cells that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream; it also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils via signal transduction pathways
Synonyms:exact_synonym: abnormal circulating G-CSF level;   abnormal circulating GCSF level;   abnormal circulating colony stimulating factor 3 (granulocyte) level;   abnormal circulating colony stimulating factor 3 level;   abnormal circulating granulocyte colony stimulating factor level



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal circulating protein level 109
            abnormal circulating cytokine level 29
              abnormal circulating CSF3 level 0
                decreased circulating CSF3 level 0
                increased circulating CSF3 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal CSF3 level 0
                abnormal circulating CSF3 level 0
                  decreased circulating CSF3 level 0
                  increased circulating CSF3 level 0
paths to the root