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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased CSF3 level
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Accession:MP:0031241 term browser browse the term
Definition:reduction in the amount of CSF3, a cytokine glycoprotein produced by endothelium, macrophages and other immune cells that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream; it also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils via signal transduction pathways
Synonyms:exact_synonym: decreased G-CSF level;   decreased GCSF level;   decreased colony stimulating factor 3 (granulocyte) level;   decreased colony stimulating factor 3 level;   decreased granulocyte colony stimulating factor level;   reduced G-CSF level;   reduced GCSF level;   reduced colony stimulating factor 3 (granulocyte) level;   reduced colony stimulating factor 3 level;   reduced granulocyte colony stimulating factor level


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    immune system phenotype 519
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal CSF3 level 0
              decreased CSF3 level 0
                decreased circulating CSF3 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5420
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              decreased cytokine level 4
                decreased CSF3 level 0
                  decreased circulating CSF3 level 0
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