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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased CSF3 level
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Accession:MP:0031241 term browser browse the term
Definition:reduction in the amount of CSF3, a cytokine glycoprotein produced by endothelium, macrophages and other immune cells that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream; it also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils via signal transduction pathways
Synonyms:exact_synonym: decreased G-CSF level;   decreased GCSF level;   decreased colony stimulating factor 3 (granulocyte) level;   decreased colony stimulating factor 3 level;   decreased granulocyte colony stimulating factor level;   reduced G-CSF level;   reduced GCSF level;   reduced colony stimulating factor 3 (granulocyte) level;   reduced colony stimulating factor 3 level;   reduced granulocyte colony stimulating factor level



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Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    immune system phenotype 5763
      abnormal immune system physiology 3496
        abnormal immune serum protein physiology 1479
          abnormal cytokine level 606
            abnormal CSF3 level 0
              decreased CSF3 level 0
                decreased circulating CSF3 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 17065
    homeostasis/metabolism phenotype 7909
      abnormal homeostasis 7051
        abnormal protein level 2371
          abnormal intercellular signaling peptide or protein level 621
            abnormal cytokine level 606
              decreased cytokine level 77
                decreased CSF3 level 0
                  decreased circulating CSF3 level 0
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