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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased CSF3 level
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Accession:MP:0031241 term browser browse the term
Definition:reduction in the amount of CSF3, a cytokine glycoprotein produced by endothelium, macrophages and other immune cells that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream; it also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils via signal transduction pathways
Synonyms:exact_synonym: decreased G-CSF level;   decreased GCSF level;   decreased colony stimulating factor 3 (granulocyte) level;   decreased colony stimulating factor 3 level;   decreased granulocyte colony stimulating factor level;   reduced G-CSF level;   reduced GCSF level;   reduced colony stimulating factor 3 (granulocyte) level;   reduced colony stimulating factor 3 level;   reduced granulocyte colony stimulating factor level


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Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal immune serum protein physiology 0
          abnormal cytokine level 0
            abnormal CSF3 level 0
              decreased CSF3 level 0
                decreased circulating CSF3 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    homeostasis/metabolism phenotype 0
      abnormal homeostasis 0
        abnormal protein level 0
          abnormal intercellular signaling peptide or protein level 0
            abnormal cytokine level 0
              decreased cytokine level 0
                decreased CSF3 level 0
                  decreased circulating CSF3 level 0
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