Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal CSF3 level
go back to main search page
Accession:MP:0031240 term browser browse the term
Definition:deviation from the normal levels of CSF3, a cytokine glycoprotein produced by endothelium, macrophages and other immune cells that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream; it also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils via signal transduction pathways
Synonyms:exact_synonym: abnormal G-CSF level;   abnormal GCSF level;   abnormal colony stimulating factor 3 (granulocyte) level;   abnormal colony stimulating factor 3 level;   abnormal granulocyte colony stimulating factor level



show annotations for term's descendants           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal CSF3 level 0
              abnormal circulating CSF3 level + 0
              decreased CSF3 level + 0
              increased CSF3 level + 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal CSF3 level 0
                abnormal circulating CSF3 level + 0
                decreased CSF3 level + 0
                increased CSF3 level + 0
paths to the root