Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:reactive type II pneumocyte hyperplasia
go back to main search page
Accession:MP:0031238 term browser browse the term
Definition:alteration to type II pneumocytes following lung injury that results in increased numbers of these cells occurring in clusters and having morphological alterations including: cuboidal shapes, increased nucleocytoplasmic ratio, enlarged nuclei, prominent nucleoli, and various alterations in their nuclear chromatin
Comment:reactive type II pneumocyte hyperplasia develops as a response to alveolar injury in various pulmonary disorders, esp. in the setting of inflammation and interstitial fibrosis and during the healing phase of diffuse alveolar damage
Synonyms:exact_synonym: reactive alveolar type II cell hyperplasia
 narrow_synonym: Type II pneumocyte hyperplasia
 xref: HP:0033328


show annotations for term's descendants           Sort by:
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 8
    respiratory system phenotype 0
      abnormal respiratory system morphology 0
        abnormal lung morphology 0
          abnormal lung epithelium morphology 0
            abnormal pulmonary alveolus epithelium morphology 0
              abnormal pulmonary alveolus epithelial cell morphology 0
                abnormal type II pneumocyte morphology 0
                  increased type II pneumocyte number 0
                    reactive type II pneumocyte hyperplasia 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 8
    respiratory system phenotype 0
      abnormal respiratory system morphology 0
        abnormal lung morphology 0
          abnormal pulmonary alveolar system morphology 0
            abnormal pulmonary acinus morphology 0
              abnormal pulmonary alveolus morphology 0
                abnormal pulmonary alveolus epithelium morphology 0
                  abnormal pulmonary alveolus epithelial cell morphology 0
                    abnormal type II pneumocyte morphology 0
                      increased type II pneumocyte number 0
                        reactive type II pneumocyte hyperplasia 0
paths to the root