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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:diffuse alveolar damage
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Accession:MP:0031237 term browser browse the term
Definition:a common histological injury pattern of the lung, whereby the early stages are characterized by epithelial cell necrosis and sloughing, fibrous exudate, edema, and hyaline membranes made of surfactant and proteins, filling the alveoli and resulting in impaired gas exchange; in later stages, alveolar type II cells and myofibroblasts proliferate within the interstitium and airspaces; the corresponding clinical entity is ARDS (acute respiratory distress syndrome)
Synonyms:xref: HP:0033006



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  mammalian phenotype 5432
    respiratory system phenotype 48
      abnormal respiratory system morphology 34
        abnormal lung morphology 27
          abnormal pulmonary alveolar system morphology 7
            diffuse alveolar damage 0
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