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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal circulating angiotensin II level
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Accession:MP:0031230 term browser browse the term
Definition:aberrant concentration in the blood of angiotensin II, a vasoactive octapeptide produced by the action of angiotensin-converting enzyme on angiotensin I; it acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone
Synonyms:narrow_synonym: abnormal plasma angiotensin II level;   abnormal serum angiotensin II level



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  mammalian phenotype 5402
    homeostasis/metabolism phenotype 1418
      abnormal homeostasis 1319
        abnormal hormone level 320
          abnormal circulating hormone level 287
            abnormal circulating angiotensin II level 0
              decreased circulating angiotensin II level 0
              increased circulating angiotensin II level 0
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